Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.041 | 0.041 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.3492 | 0.5983 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.3492 | 1 |
Echinococcus granulosus | lamin | 0.0026 | 0.3492 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.041 | 0.041 |
Schistosoma mansoni | lamin | 0.0026 | 0.3492 | 0.5983 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.3492 | 0.3492 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3354 | 0.3354 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.5561 | 0.5561 |
Onchocerca volvulus | 0.0026 | 0.3492 | 0.5 | |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.041 | 0.041 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.3492 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.5561 | 0.5561 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.3492 | 0.3492 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.3492 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.3492 | 0.3492 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.5561 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 1 | 1 |
Onchocerca volvulus | 0.0026 | 0.3492 | 0.5 | |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.041 | 0.041 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 1 | 1 |
Echinococcus multilocularis | lamin | 0.0026 | 0.3492 | 1 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.3492 | 0.3492 |
Echinococcus multilocularis | musashi | 0.0026 | 0.3492 | 1 |
Schistosoma mansoni | lamin | 0.0026 | 0.3492 | 0.5983 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.3492 | 0.3492 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.