Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Bile acid receptor homolog | 0.0223 | 0.4837 | 1 |
Brugia malayi | ecdysteroid receptor | 0.0223 | 0.4837 | 0.8583 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 0.5636 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0051 | 0 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0174 | 0.345 | 0.1027 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0165 | 0.32 | 0.6615 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0051 | 0 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0051 | 0 | 0.5 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0051 | 0 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 0.5636 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 0.5636 | 1 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0251 | 0.5636 | 1 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0251 | 0.5636 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 0.5636 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0223 | 0.4837 | 0.8583 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0051 | 0 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 0.5636 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0051 | 0 | 0.5 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0051 | 0 | 0.5 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0051 | 0 | 0.5 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0051 | 0 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0174 | 0.345 | 0.1027 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0051 | 0 | 0.5 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0051 | 0 | 0.5 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0051 | 0 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0251 | 0.5636 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0051 | 0 | 0.5 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0051 | 0 | 0.5 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0051 | 0 | 0.5 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0051 | 0 | 0.5 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0051 | 0 | 0.5 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0051 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.