Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative | 0.0123 | 0.0868 | 0.1727 |
Brugia malayi | Pre-SET motif family protein | 0.0204 | 0.1497 | 0.1496 |
Plasmodium vivax | SET domain protein, putative | 0.0029 | 0.0136 | 0.1424 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0034 | 0.0038 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0258 | 0.0243 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0648 | 0.4955 | 0.4955 |
Echinococcus granulosus | pyruvate kinase | 0.0017 | 0.0039 | 0.0024 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0123 | 0.0868 | 0.1727 |
Echinococcus multilocularis | pyruvate kinase | 0.0033 | 0.0163 | 0.0149 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0033 | 0.0163 | 0.0872 |
Brugia malayi | AMP-binding enzyme family protein | 0.0046 | 0.027 | 0.027 |
Echinococcus multilocularis | protein patched | 0.0041 | 0.0231 | 0.0216 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0124 | 0.0874 | 0.086 |
Mycobacterium tuberculosis | Probable protease II PtrBb [second part] (oligopeptidase B) | 0.0123 | 0.0868 | 0.9935 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0123 | 0.0868 | 0.0855 |
Echinococcus multilocularis | Ankyrin | 0.0014 | 0.0019 | 0.0004 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0034 | 0.0038 |
Giardia lamblia | Pyruvate kinase | 0.0017 | 0.0039 | 0.0067 |
Brugia malayi | glutathione reductase | 0.0046 | 0.0269 | 0.0269 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0016 | 0.0034 | 0.0219 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0046 | 0.027 | 0.2975 |
Schistosoma mansoni | pyruvate kinase | 0.0033 | 0.0163 | 0.0149 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0034 | 0.0038 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0014 | 0.0015 | 0.0169 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0258 | 0.0243 |
Loa Loa (eye worm) | pyruvate kinase-PB | 0.0023 | 0.0086 | 0.0071 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.0648 | 0.4955 | 1 |
Mycobacterium tuberculosis | Probable reductase | 0.0106 | 0.0732 | 0.8371 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0029 | 0.0136 | 0.0122 |
Brugia malayi | Protein kinase domain containing protein | 0.0014 | 0.0018 | 0.0018 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0164 | 0.1878 |
Loa Loa (eye worm) | carboxylesterase | 0.0124 | 0.0874 | 0.086 |
Brugia malayi | AMP-binding enzyme family protein | 0.0014 | 0.0015 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0286 | 0.0272 |
Loa Loa (eye worm) | hypothetical protein | 0.0248 | 0.1844 | 0.1832 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0106 | 0.0732 | 0.8371 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0219 | 0.0205 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0041 | 0.0231 | 0.0216 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0046 | 0.027 | 0.2995 |
Chlamydia trachomatis | pyruvate kinase | 0.0033 | 0.0163 | 0.8912 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.0183 | 0.0169 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0016 | 0.0034 | 0.0219 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0046 | 0.0269 | 0.0255 |
Brugia malayi | Death domain containing protein | 0.0014 | 0.0018 | 0.0018 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0733 | 0.5622 | 0.5616 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0018 | 0.0003 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0124 | 0.0874 | 0.086 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0123 | 0.0868 | 1 |
Trypanosoma brucei | serine peptidase, clan SC, family S9A-like protein | 0.0123 | 0.0868 | 0.1727 |
Toxoplasma gondii | acylaminoacyl-peptidase, putative | 0.0123 | 0.0868 | 0.2153 |
Trypanosoma cruzi | serine peptidase, clan SC, family S9A-like protein, putative | 0.0123 | 0.0868 | 0.1727 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0046 | 0.027 | 0.0517 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0016 | 0.0034 | 0.011 |
Echinococcus multilocularis | neuroligin | 0.0124 | 0.0874 | 0.086 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0124 | 0.0874 | 1 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0014 | 0.0018 | 0.0003 |
Mycobacterium ulcerans | hypothetical protein | 0.0046 | 0.027 | 0.2975 |
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.0648 | 0.4955 | 0.4948 |
Echinococcus multilocularis | acylamino acid releasing enzyme | 0.0123 | 0.0868 | 0.0855 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0041 | 0.0231 | 0.0216 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0123 | 0.0868 | 0.0855 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0086 | 0.0071 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0183 | 0.1972 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0046 | 0.027 | 0.2975 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0014 | 0.0015 | 0.0014 |
Onchocerca volvulus | 0.0124 | 0.0874 | 0.086 | |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0136 | 0.0122 |
Echinococcus multilocularis | tumor protein p63 | 0.0331 | 0.2487 | 0.2476 |
Onchocerca volvulus | 0.0029 | 0.0136 | 0.0122 | |
Toxoplasma gondii | hypothetical protein | 0.0123 | 0.0868 | 0.2153 |
Onchocerca volvulus | Prolyl endopeptidase homolog | 0.0123 | 0.0868 | 0.0855 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0258 | 0.0243 |
Echinococcus granulosus | pyruvate kinase | 0.0017 | 0.0039 | 0.0024 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0136 | 0.0122 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0258 | 0.0243 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0123 | 0.0868 | 0.5016 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0303 | 0.0289 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0034 | 0.0038 |
Brugia malayi | Thioredoxin reductase | 0.0046 | 0.0269 | 0.0269 |
Leishmania major | pyruvate kinase | 0.0033 | 0.0163 | 0.03 |
Onchocerca volvulus | 0.0047 | 0.0277 | 0.0262 | |
Loa Loa (eye worm) | thioredoxin reductase | 0.0046 | 0.0269 | 0.0255 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0046 | 0.027 | 0.2975 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0046 | 0.0269 | 0.0515 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0123 | 0.0868 | 0.0855 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0258 | 0.0243 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0016 | 0.0034 | 0.0038 |
Mycobacterium tuberculosis | Probable peptidase | 0.0123 | 0.0868 | 0.9935 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0179 | 0.0164 |
Echinococcus granulosus | death domain containing protein | 0.0014 | 0.0018 | 0.0003 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0123 | 0.0868 | 1 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0106 | 0.0732 | 0.8371 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0258 | 0.0243 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.1295 | 1 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0123 | 0.0868 | 0.0868 |
Brugia malayi | AMP-binding enzyme family protein | 0.0046 | 0.027 | 0.027 |
Brugia malayi | Carboxylesterase family protein | 0.0124 | 0.0874 | 0.0874 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0232 | 0.1713 | 0.1701 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0106 | 0.0732 | 0.8371 |
Echinococcus multilocularis | prolyl endopeptidase | 0.0123 | 0.0868 | 0.0855 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0035 | 0.0179 | 1 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0138 | 0.0982 | 0.0969 |
Echinococcus granulosus | Ankyrin | 0.0014 | 0.0019 | 0.0004 |
Onchocerca volvulus | 0.0124 | 0.0874 | 0.086 | |
Plasmodium falciparum | glutathione reductase | 0.0046 | 0.0269 | 0.2983 |
Onchocerca volvulus | 0.0124 | 0.0874 | 0.086 | |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0096 | 0.066 | 0.0646 |
Echinococcus granulosus | tumor protein p63 | 0.0331 | 0.2487 | 0.2476 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.0874 | 0.086 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0106 | 0.0732 | 0.8399 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0035 | 0.0179 | 0.1923 |
Schistosoma mansoni | patched 1 | 0.0041 | 0.0231 | 0.0216 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0123 | 0.0868 | 0.5016 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0123 | 0.0868 | 1 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0014 | 0.0015 | 0.0014 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0014 | 0.0015 | 0.0169 |
Mycobacterium leprae | Probable pyruvate kinase PykA | 0.0033 | 0.0163 | 0.1738 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0124 | 0.0874 | 0.086 |
Brugia malayi | Pyruvate kinase, muscle isozyme | 0.0033 | 0.0163 | 0.0163 |
Echinococcus granulosus | pyruvate kinase | 0.0033 | 0.0163 | 0.0149 |
Onchocerca volvulus | 0.0232 | 0.1717 | 0.1705 | |
Onchocerca volvulus | 0.0124 | 0.0874 | 0.086 | |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0056 | 0.0346 | 0.0332 |
Echinococcus granulosus | pyruvate kinase | 0.0017 | 0.0039 | 0.0024 |
Brugia malayi | Uncoordinated protein 44 | 0.0014 | 0.0018 | 0.0018 |
Schistosoma mansoni | pyruvate kinase | 0.0033 | 0.0163 | 0.0149 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0041 | 0.0231 | 0.0216 |
Loa Loa (eye worm) | pyruvate kinase | 0.0033 | 0.0163 | 0.0149 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0014 | 0.0015 | 0.0169 |
Onchocerca volvulus | 0.0124 | 0.0874 | 0.086 | |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0046 | 0.027 | 0.2995 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0048 | 0.0286 | 0.0272 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0098 | 0.0671 | 0.0658 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0123 | 0.0868 | 0.0855 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0123 | 0.0868 | 0.0868 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0231 | 0.1271 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0056 | 0.0346 | 0.0332 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0277 | 0.0262 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0016 | 0.0034 | 0.0047 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0219 | 0.0205 |
Echinococcus granulosus | expressed conserved protein | 0.0091 | 0.0614 | 0.06 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.0648 | 0.4955 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.0874 | 0.086 |
Brugia malayi | Carboxylesterase family protein | 0.0733 | 0.5622 | 0.5622 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0046 | 0.027 | 0.2995 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0124 | 0.0874 | 0.086 |
Toxoplasma gondii | thioredoxin reductase | 0.0046 | 0.0269 | 0.0642 |
Echinococcus granulosus | neuroligin | 0.0124 | 0.0874 | 0.086 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0033 | 0.0163 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0019 | 0.0004 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0035 | 0.0179 | 0.1923 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0029 | 0.0136 | 0.0122 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0124 | 0.0874 | 0.086 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0124 | 0.0874 | 0.086 |
Schistosoma mansoni | pyruvate kinase | 0.0017 | 0.0039 | 0.0024 |
Plasmodium vivax | glutathione reductase, putative | 0.0046 | 0.0269 | 0.2983 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0035 | 0.0179 | 0.191 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0016 | 0.0034 | 0.022 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0016 | 0.0034 | 0.0219 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0056 | 0.0346 | 0.3962 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0046 | 0.027 | 0.2995 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.1295 | 1 | 1 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0794 | 0.6096 | 0.6091 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0016 | 0.0034 | 0.022 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0231 | 0.0216 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0016 | 0.0034 | 0.022 |
Leishmania major | pyruvate kinase | 0.0033 | 0.0163 | 0.03 |
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.0123 | 0.0868 | 1 |
Mycobacterium tuberculosis | Probable pyruvate kinase PykA | 0.0033 | 0.0163 | 0.1866 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0046 | 0.027 | 0.3094 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0123 | 0.0868 | 1 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0014 | 0.0015 | 0.0169 |
Leishmania major | oligopeptidase b | 0.0123 | 0.0868 | 0.1727 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0046 | 0.027 | 0.2975 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0014 | 0.0015 | 0.0169 |
Plasmodium falciparum | thioredoxin reductase | 0.0046 | 0.0269 | 0.2983 |
Onchocerca volvulus | Netrin receptor homolog | 0.0014 | 0.0018 | 0.0003 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0046 | 0.027 | 0.2975 |
Onchocerca volvulus | 0.0048 | 0.0286 | 0.0272 | |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0016 | 0.0034 | 0.0038 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0034 | 0.5 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0046 | 0.027 | 0.2975 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0258 | 0.0243 |
Brugia malayi | Pre-SET motif family protein | 0.0029 | 0.0136 | 0.0136 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0183 | 0.1972 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0046 | 0.0269 | 0.3082 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0014 | 0.0019 | 0.0004 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0014 | 0.0015 | 0.0169 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0123 | 0.0868 | 1 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0033 | 0.0163 | 0.03 |
Trypanosoma brucei | Alpha/beta hydrolase domain-containing protein | 0.0123 | 0.0868 | 0.1727 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.0648 | 0.4955 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0164 | 0.1878 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0034 | 0.0038 |
Brugia malayi | hypothetical protein | 0.0124 | 0.0874 | 0.0874 |
Trypanosoma brucei | oligopeptidase b | 0.0123 | 0.0868 | 0.1727 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0033 | 0.0163 | 0.0149 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0117 | 0.0823 | 0.9475 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0096 | 0.066 | 0.0646 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0014 | 0.0018 | 0.0018 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0123 | 0.0868 | 0.0868 |
Loa Loa (eye worm) | pyruvate kinase | 0.0033 | 0.0163 | 0.0149 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0204 | 0.1497 | 0.1484 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0014 | 0.0015 | 0.0169 |
Plasmodium falciparum | pyruvate kinase 2 | 0.0017 | 0.0039 | 0.0286 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0124 | 0.0874 | 0.086 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0046 | 0.0269 | 0.0255 |
Echinococcus multilocularis | pyruvate kinase | 0.0026 | 0.0109 | 0.0095 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0124 | 0.0874 | 0.505 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.027 | 0.0256 |
Echinococcus multilocularis | protein dispatched 1 | 0.0047 | 0.0276 | 0.0262 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0016 | 0.0034 | 0.0038 |
Onchocerca volvulus | 0.0046 | 0.027 | 0.0256 | |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0138 | 0.0982 | 0.0969 |
Echinococcus granulosus | prolyl endopeptidase | 0.0123 | 0.0868 | 0.0855 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.1295 | 1 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0046 | 0.027 | 0.2975 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0014 | 0.0018 | 0.0003 |
Echinococcus granulosus | pyruvate kinase | 0.0033 | 0.0163 | 0.0149 |
Schistosoma mansoni | acetylcholinesterase | 0.0124 | 0.0874 | 0.086 |
Brugia malayi | Carboxylesterase family protein | 0.0124 | 0.0874 | 0.0874 |
Leishmania major | oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein | 0.0123 | 0.0868 | 0.1727 |
Brugia malayi | AMP-binding enzyme family protein | 0.0014 | 0.0015 | 0.0014 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0014 | 0.0015 | 0.0169 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0056 | 0.0346 | 0.3859 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0123 | 0.0868 | 0.1727 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0016 | 0.0034 | 0.0038 |
Echinococcus multilocularis | pyruvate kinase | 0.0017 | 0.0039 | 0.0024 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0029 | 0.0136 | 0.0307 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.027 | 0.0256 |
Echinococcus multilocularis | pyruvate kinase | 0.0017 | 0.0039 | 0.0024 |
Brugia malayi | hypothetical protein | 0.0399 | 0.302 | 0.3019 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0016 | 0.0034 | 0.5 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0106 | 0.0732 | 0.8371 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0183 | 0.0183 |
Toxoplasma gondii | pyruvate kinase PyKII | 0.0017 | 0.0039 | 0.0062 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0117 | 0.0823 | 0.9422 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0056 | 0.0346 | 0.0332 |
Brugia malayi | hypothetical protein | 0.0232 | 0.1713 | 0.1713 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0034 | 0.0038 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0034 | 0.0038 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0016 | 0.0034 | 0.022 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0016 | 0.0034 | 0.011 |
Trypanosoma brucei | prolyl endopeptidase | 0.0123 | 0.0868 | 0.1727 |
Schistosoma mansoni | acylaminoacyl-peptidase (S09 family) | 0.0123 | 0.0868 | 0.0855 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0183 | 0.0169 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0106 | 0.0732 | 0.8371 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0124 | 0.0874 | 0.505 |
Trypanosoma cruzi | pyruvate kinase 2, putative | 0.0033 | 0.0163 | 0.03 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0258 | 0.0243 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0117 | 0.0823 | 0.9422 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0016 | 0.0034 | 0.0033 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0117 | 0.0823 | 0.9422 |
Giardia lamblia | Pyruvate kinase | 0.0033 | 0.0163 | 0.1552 |
Brugia malayi | AMP-binding enzyme family protein | 0.0014 | 0.0015 | 0.0014 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.0277 | 0.0276 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0123 | 0.0868 | 1 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0016 | 0.0034 | 0.0038 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0035 | 0.0179 | 0.2047 |
Trypanosoma cruzi | prolyl endopeptidase | 0.0123 | 0.0868 | 0.1727 |
Loa Loa (eye worm) | hypothetical protein | 0.0733 | 0.5622 | 0.5616 |
Toxoplasma gondii | pyruvate kinase PyK1 | 0.0033 | 0.0163 | 0.0374 |
Schistosoma mansoni | gliotactin | 0.0124 | 0.0874 | 0.086 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.0277 | 0.0262 |
Brugia malayi | Pyruvate kinase, M2 isozyme | 0.0033 | 0.0163 | 0.0163 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0046 | 0.027 | 0.3094 |
Loa Loa (eye worm) | pyruvate kinase | 0.0033 | 0.0163 | 0.0149 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0096 | 0.066 | 0.0659 |
Entamoeba histolytica | pyruvate kinase, putative | 0.0023 | 0.0086 | 0.0835 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.027 | 0.0256 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0232 | 0.1713 | 0.1701 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0123 | 0.0868 | 1 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0014 | 0.0015 | 0.0169 |
Echinococcus granulosus | acylamino acid releasing enzyme | 0.0123 | 0.0868 | 0.0855 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0029 | 0.0136 | 0.0122 |
Trypanosoma brucei | pyruvate kinase 1 | 0.0033 | 0.0163 | 0.03 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.0123 | 0.0868 | 0.9933 |
Plasmodium vivax | hypothetical protein, conserved | 0.0123 | 0.0868 | 1 |
Trichomonas vaginalis | Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase | 0.0123 | 0.0868 | 0.5016 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0029 | 0.0136 | 0.0122 |
Echinococcus multilocularis | expressed conserved protein | 0.0091 | 0.0614 | 0.06 |
Loa Loa (eye worm) | carboxylesterase | 0.0124 | 0.0874 | 0.086 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0016 | 0.0034 | 0.0047 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0164 | 0.1878 |
Plasmodium falciparum | glutathione reductase | 0.0016 | 0.0034 | 0.022 |
Loa Loa (eye worm) | hypothetical protein | 0.0733 | 0.5622 | 0.5616 |
Plasmodium vivax | pyruvate kinase, putative | 0.0033 | 0.0163 | 0.1738 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.0183 | 0.0169 |
Brugia malayi | Carboxylesterase family protein | 0.0733 | 0.5622 | 0.5622 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0056 | 0.0346 | 0.0671 |
Mycobacterium ulcerans | pyruvate kinase | 0.0033 | 0.0163 | 0.1726 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.1295 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0124 | 0.0874 | 1 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.0648 | 0.4955 | 0.4948 |
Echinococcus granulosus | carboxylesterase 5A | 0.0733 | 0.5622 | 0.5616 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0124 | 0.0874 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0179 | 0.0164 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0733 | 0.5622 | 0.5616 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.0874 | 0.086 |
Trypanosoma cruzi | oligopeptidase B-like protein, putative | 0.0123 | 0.0868 | 0.1727 |
Echinococcus granulosus | acetylcholinesterase | 0.0733 | 0.5622 | 0.5616 |
Plasmodium falciparum | pyruvate kinase | 0.0033 | 0.0163 | 0.1738 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0136 | 0.0122 |
Echinococcus granulosus | acetylcholinesterase | 0.0733 | 0.5622 | 0.5616 |
Schistosoma mansoni | hypothetical protein | 0.0014 | 0.0018 | 0.0003 |
Brugia malayi | CHE-14 protein | 0.0041 | 0.0231 | 0.0231 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0016 | 0.0034 | 0.0038 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.1295 | 1 | 1 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0016 | 0.0034 | 0.0019 |
Schistosoma mansoni | netrin receptor unc5 | 0.0014 | 0.0018 | 0.0003 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0216 | 0.1594 | 0.1582 |
Trypanosoma brucei | prolyl oligopeptidase, putative | 0.0123 | 0.0868 | 0.1727 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.0874 | 0.086 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0016 | 0.0034 | 0.0038 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0016 | 0.0034 | 0.0384 |
Onchocerca volvulus | 0.0017 | 0.0044 | 0.003 | |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0014 | 0.0015 | 0.0169 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0046 | 0.0269 | 0.2983 |
Echinococcus multilocularis | pyruvate kinase | 0.0017 | 0.0039 | 0.0024 |
Trypanosoma brucei | pyruvate kinase 1, putative | 0.0033 | 0.0163 | 0.03 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0216 | 0.1594 | 0.1582 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0056 | 0.0346 | 0.0346 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0052 | 0.0317 | 0.0302 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0124 | 0.0874 | 0.086 |
Echinococcus multilocularis | acetylcholinesterase | 0.0733 | 0.5622 | 0.5616 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0183 | 0.1972 |
Loa Loa (eye worm) | glutathione reductase | 0.0046 | 0.0269 | 0.0255 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0258 | 0.0257 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0128 | 0.0113 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.0874 | 0.086 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0046 | 0.027 | 0.0517 |
Trichomonas vaginalis | pyruvate kinase, putative | 0.0033 | 0.0163 | 0.0872 |
Plasmodium vivax | pyruvate kinase 2, putative | 0.0017 | 0.0039 | 0.0286 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.1713 | 0.1701 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0016 | 0.0034 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0179 | 0.0164 |
Plasmodium falciparum | peptidase, putative | 0.0123 | 0.0868 | 1 |
Toxoplasma gondii | dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein | 0.0522 | 0.3979 | 1 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0124 | 0.0874 | 0.086 |
Brugia malayi | Carboxylesterase family protein | 0.0124 | 0.0874 | 0.0874 |
Brugia malayi | Carboxylesterase family protein | 0.0124 | 0.0874 | 0.0874 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0179 | 0.0164 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0014 | 0.0018 | 0.0003 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0124 | 0.0874 | 0.086 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.0183 | 0.0169 |
Echinococcus multilocularis | netrin receptor unc 5 | 0.0014 | 0.0018 | 0.0003 |
Brugia malayi | AMP-binding enzyme family protein | 0.0014 | 0.0015 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.0868 | 0.0855 |
Brugia malayi | AMP-binding enzyme family protein | 0.0046 | 0.027 | 0.027 |
Onchocerca volvulus | Pyruvate kinase homolog | 0.0033 | 0.0163 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.066 | 0.0646 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0136 | 0.0122 |
Echinococcus multilocularis | acetylcholinesterase | 0.0733 | 0.5622 | 0.5616 |
Echinococcus multilocularis | pyruvate kinase | 0.0033 | 0.0163 | 0.0149 |
Toxoplasma gondii | prolyl endopeptidase | 0.0123 | 0.0868 | 0.2153 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.0874 | 0.086 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0733 | 0.5622 | 0.5616 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0016 | 0.0034 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0179 | 0.0164 |
Loa Loa (eye worm) | carboxylesterase | 0.0733 | 0.5622 | 0.5616 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0016 | 0.0034 | 0.0019 |
Trypanosoma brucei | trypanothione reductase | 0.0046 | 0.0269 | 0.0515 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0046 | 0.027 | 0.0517 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.0868 | 0.0855 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0219 | 0.0205 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0124 | 0.0874 | 1 |
Trypanosoma cruzi | oligopeptidase b | 0.0123 | 0.0868 | 0.1727 |
Plasmodium falciparum | thioredoxin reductase | 0.0016 | 0.0034 | 0.022 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0046 | 0.027 | 0.2995 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.0648 | 0.4955 | 1 |
Leishmania major | trypanothione reductase | 0.0046 | 0.0269 | 0.0515 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0124 | 0.0874 | 0.086 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0096 | 0.066 | 0.7558 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0123 | 0.0868 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0164 | 0.1878 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.0874 | 0.086 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0041 | 0.0231 | 0.0216 |
Trypanosoma cruzi | oligopeptidase b | 0.0123 | 0.0868 | 0.1727 |
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.0648 | 0.4955 | 0.4948 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0056 | 0.0346 | 0.3859 |
Loa Loa (eye worm) | hypothetical protein | 0.0399 | 0.302 | 0.3009 |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0014 | 0.0018 | 0.0003 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.0183 | 0.1972 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0016 | 0.0034 | 0.0038 |
Treponema pallidum | NADH oxidase | 0.0016 | 0.0034 | 0.5 |
Echinococcus granulosus | netrin receptor unc 5 | 0.0014 | 0.0018 | 0.0003 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0163 | 0.0149 |
Trichomonas vaginalis | set domain proteins, putative | 0.0232 | 0.1716 | 1 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.0648 | 0.4955 | 1 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0016 | 0.0034 | 0.0019 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.0219 | 0.0205 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0014 | 0.0015 | 0.0169 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Antifertility potency (functional) | < 10 | In vivo for antifertility potency in rat at 200 microg/Kg/day | ChEMBL. | 2738897 |
Estrogenic potency (functional) | = 0.05 | Compound was evaluated in vivo for estrogenic receptor potency relative to ethynylestradiol in rat . | ChEMBL. | 2738897 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.