Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.2501 | 0.2501 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.2501 | 0.3552 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.2501 | 0.2501 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.5155 | 0.7321 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0034 | 0.0925 | 0.1313 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.314 | 0.6092 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0028 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.5155 | 0.7321 |
Plasmodium falciparum | phd finger protein, putative | 0.0028 | 0 | 0.5 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0034 | 0.0925 | 0.1313 |
Echinococcus granulosus | jumonji domain containing protein | 0.0039 | 0.1721 | 0.1721 |
Brugia malayi | RNA binding protein | 0.0062 | 0.5155 | 0.5155 |
Brugia malayi | jmjC domain containing protein | 0.0034 | 0.0925 | 0.0925 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.5155 | 0.5155 |
Giardia lamblia | PHD finger protein 15 | 0.0028 | 0 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.2501 | 0.2501 |
Onchocerca volvulus | Alhambra homolog | 0.0028 | 0 | 0.5 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0044 | 0.2501 | 0.4851 |
Schistosoma mansoni | jumonji domain containing protein | 0.0074 | 0.7041 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.5155 | 0.7321 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0028 | 0 | 0.5 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0093 | 1 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0028 | 0 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.5155 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0044 | 0.2501 | 0.2501 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.2501 | 0.3552 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.5155 | 1 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0039 | 0.1721 | 0.1721 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.2501 | 0.2501 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.2501 | 0.3552 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.5155 | 0.5155 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.5155 | 0.7321 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.5155 | 1 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0034 | 0.0925 | 0.0925 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0093 | 1 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.5155 | 0.5155 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.5155 | 0.5155 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.5155 | 0.7321 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0034 | 0.0925 | 0.1794 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0034 | 0.0925 | 0.0925 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0058 | 0.468 | 0.9079 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.