Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Alhambra homolog | 0.006 | 0.0242 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0332 | 0.1262 |
Brugia malayi | Heterochromatin protein 1 | 0.007 | 0.0358 | 0.1362 |
Loa Loa (eye worm) | TAR-binding protein | 0.0267 | 0.2629 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.0697 | 0.2651 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0267 | 0.2629 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0267 | 0.2629 | 0.2446 |
Brugia malayi | TAR-binding protein | 0.0267 | 0.2629 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0267 | 0.2629 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0267 | 0.2629 | 1 |
Brugia malayi | PHD-finger family protein | 0.006 | 0.0242 | 0.092 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0073 | 0.0389 | 0.0616 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0146 | 0.1233 | 0.4154 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0146 | 0.1233 | 0.1016 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.01 | 0.0697 | 0.2651 |
Schistosoma mansoni | tar DNA-binding protein | 0.0267 | 0.2629 | 1 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0073 | 0.0389 | 0.0616 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0146 | 0.1233 | 0.4692 |
Trichomonas vaginalis | chromobox protein, putative | 0.007 | 0.0358 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0073 | 0.0389 | 0.1479 |
Schistosoma mansoni | jumonji domain containing protein | 0.0157 | 0.1361 | 0.4689 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0146 | 0.1233 | 0.1016 |
Trichomonas vaginalis | chromobox protein, putative | 0.0042 | 0.0035 | 0.0969 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0242 | 0.092 |
Brugia malayi | jmjC domain containing protein | 0.0198 | 0.1831 | 0.6967 |
Schistosoma mansoni | tar DNA-binding protein | 0.0267 | 0.2629 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0125 | 0.0986 | 0.375 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0267 | 0.2629 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.01 | 0.0697 | 0.2651 |
Echinococcus multilocularis | chromobox protein 1 | 0.007 | 0.0358 | 0.0119 |
Plasmodium vivax | hypothetical protein, conserved | 0.006 | 0.0242 | 0.5 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.007 | 0.0358 | 0.1362 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0198 | 0.1831 | 0.1629 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0042 | 0.0035 | 0.1434 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0146 | 0.1233 | 0.4154 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0228 | 0.2176 | 0.5 |
Brugia malayi | RNA binding protein | 0.0267 | 0.2629 | 1 |
Giardia lamblia | PHD finger protein 15 | 0.006 | 0.0242 | 0.5 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0073 | 0.0389 | 0.0616 |
Echinococcus granulosus | chromobox protein 1 | 0.007 | 0.0358 | 0.0487 |
Plasmodium falciparum | phd finger protein, putative | 0.006 | 0.0242 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.0332 | 0.0377 |
Schistosoma mansoni | tar DNA-binding protein | 0.0267 | 0.2629 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0267 | 0.2629 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0042 | 0.0035 | 0.0969 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0073 | 0.0389 | 0.0151 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0068 | 0.0332 | 0.1262 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0146 | 0.1233 | 0.4154 |
Trichomonas vaginalis | chromobox protein, putative | 0.007 | 0.0358 | 1 |
Echinococcus multilocularis | chromobox protein 1 | 0.007 | 0.0358 | 0.0119 |
Echinococcus granulosus | chromobox protein 1 | 0.007 | 0.0358 | 0.0487 |
Echinococcus granulosus | jumonji domain containing protein | 0.0084 | 0.0515 | 0.1146 |
Schistosoma mansoni | tar DNA-binding protein | 0.0267 | 0.2629 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.01 | 0.0697 | 0.2651 |
Brugia malayi | Bromodomain containing protein | 0.006 | 0.0242 | 0.092 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0198 | 0.1831 | 0.6659 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0073 | 0.0389 | 0.1479 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0146 | 0.1233 | 0.4692 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.006 | 0.0242 | 0.5 |
Schistosoma mansoni | chromobox protein | 0.007 | 0.0358 | 0.0487 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0084 | 0.0515 | 0.028 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0146 | 0.1233 | 0.4154 |
Loa Loa (eye worm) | PHD-finger family protein | 0.006 | 0.0242 | 0.092 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.0741 | 0.2819 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.006 | 0.0242 | 0.5 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0146 | 0.1233 | 0.4154 |
Schistosoma mansoni | chromobox protein | 0.007 | 0.0358 | 0.0487 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.