Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0074 | 0.0387 | 0.0635 |
Trichomonas vaginalis | chromobox protein, putative | 0.0074 | 0.0383 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0101 | 0.0708 | 0.2687 |
Echinococcus granulosus | jumonji domain containing protein | 0.0085 | 0.0519 | 0.1181 |
Loa Loa (eye worm) | TAR-binding protein | 0.0264 | 0.2636 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0146 | 0.1235 | 0.4686 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0074 | 0.0387 | 0.0635 |
Loa Loa (eye worm) | hypothetical protein | 0.0105 | 0.0752 | 0.2855 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0061 | 0.0235 | 0.5 |
Echinococcus granulosus | chromobox protein 1 | 0.0074 | 0.0383 | 0.0617 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0085 | 0.0519 | 0.029 |
Onchocerca volvulus | Alhambra homolog | 0.0061 | 0.0235 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0146 | 0.1235 | 0.4165 |
Schistosoma mansoni | chromobox protein | 0.0074 | 0.0383 | 0.0617 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0146 | 0.1235 | 0.1024 |
Brugia malayi | Bromodomain containing protein | 0.0061 | 0.0235 | 0.0892 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.02 | 0.1882 | 0.1687 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0146 | 0.1235 | 0.4165 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0074 | 0.0383 | 0.1454 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0061 | 0.0235 | 0.5 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0044 | 0.0037 | 0.1579 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.02 | 0.1882 | 0.6862 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0264 | 0.2636 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0146 | 0.1235 | 0.4686 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0224 | 0.2155 | 0.5 |
Brugia malayi | RNA binding protein | 0.0264 | 0.2636 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0264 | 0.2636 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0126 | 0.1006 | 0.3817 |
Brugia malayi | jmjC domain containing protein | 0.0074 | 0.0387 | 0.147 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0101 | 0.0708 | 0.2687 |
Brugia malayi | Heterochromatin protein 1 | 0.0074 | 0.0383 | 0.1454 |
Plasmodium vivax | hypothetical protein, conserved | 0.0061 | 0.0235 | 0.5 |
Trichomonas vaginalis | chromobox protein, putative | 0.0044 | 0.0037 | 0.0969 |
Schistosoma mansoni | tar DNA-binding protein | 0.0264 | 0.2636 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0329 | 0.125 |
Trichomonas vaginalis | chromobox protein, putative | 0.0074 | 0.0383 | 1 |
Echinococcus multilocularis | chromobox protein 1 | 0.0074 | 0.0383 | 0.0152 |
Brugia malayi | PHD-finger family protein | 0.0061 | 0.0235 | 0.0892 |
Schistosoma mansoni | tar DNA-binding protein | 0.0264 | 0.2636 | 1 |
Plasmodium falciparum | phd finger protein, putative | 0.0061 | 0.0235 | 0.5 |
Schistosoma mansoni | chromobox protein | 0.0074 | 0.0383 | 0.0617 |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.0329 | 0.0393 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0101 | 0.0708 | 0.2687 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0146 | 0.1235 | 0.1024 |
Trichomonas vaginalis | chromobox protein, putative | 0.0044 | 0.0037 | 0.0969 |
Schistosoma mansoni | jumonji domain containing protein | 0.0159 | 0.1395 | 0.4832 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0146 | 0.1235 | 0.4165 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0061 | 0.0235 | 0.0892 |
Brugia malayi | jmjC domain containing protein | 0.02 | 0.1882 | 0.7142 |
Schistosoma mansoni | tar DNA-binding protein | 0.0264 | 0.2636 | 1 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0074 | 0.0387 | 0.0156 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0074 | 0.0387 | 0.0635 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0146 | 0.1235 | 0.4165 |
Echinococcus multilocularis | chromobox protein 1 | 0.0074 | 0.0383 | 0.0152 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.0708 | 0.2687 |
Echinococcus granulosus | chromobox protein 1 | 0.0074 | 0.0383 | 0.0617 |
Schistosoma mansoni | tar DNA-binding protein | 0.0264 | 0.2636 | 1 |
Giardia lamblia | PHD finger protein 15 | 0.0061 | 0.0235 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0069 | 0.0329 | 0.125 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0074 | 0.0387 | 0.147 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0146 | 0.1235 | 0.4165 |
Loa Loa (eye worm) | RNA binding protein | 0.0264 | 0.2636 | 1 |
Brugia malayi | TAR-binding protein | 0.0264 | 0.2636 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0264 | 0.2636 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0264 | 0.2636 | 0.2458 |
Echinococcus granulosus | tar DNA binding protein | 0.0264 | 0.2636 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0235 | 0.0892 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.