Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1174 | 0.4919 |
Mycobacterium leprae | conserved hypothetical protein | 0.007 | 0.1174 | 0.5 |
Echinococcus multilocularis | GPCR, family 2 | 0.0032 | 0.0277 | 0.0339 |
Brugia malayi | RNA binding protein | 0.0061 | 0.0963 | 0.4036 |
Echinococcus multilocularis | geminin | 0.0349 | 0.7665 | 0.939 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.007 | 0.1174 | 0.4919 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0069 | 0.1137 | 0.4766 |
Onchocerca volvulus | 0.007 | 0.1174 | 1 | |
Echinococcus multilocularis | expressed protein | 0.037 | 0.8163 | 1 |
Brugia malayi | beta-lactamase family protein | 0.007 | 0.1174 | 0.4919 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.007 | 0.1174 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0061 | 0.0963 | 0.4036 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.1878 | 0.7872 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.007 | 0.1174 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.01 | 0.1875 | 0.786 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.01 | 0.1878 | 0.7872 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0963 | 0.1256 |
Echinococcus granulosus | GPCR family 2 | 0.0032 | 0.0277 | 0.0314 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.007 | 0.1174 | 0.1329 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1174 | 0.4919 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.007 | 0.1174 | 0.1438 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0277 | 0.1161 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1174 | 0.4919 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0032 | 0.0277 | 0.1161 |
Loa Loa (eye worm) | beta-lactamase | 0.007 | 0.1174 | 0.4919 |
Echinococcus granulosus | expressed protein | 0.037 | 0.8163 | 0.9244 |
Brugia malayi | MH2 domain containing protein | 0.0122 | 0.2386 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.007 | 0.1174 | 0.5 |
Loa Loa (eye worm) | TAR-binding protein | 0.0061 | 0.0963 | 0.4036 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0277 | 0.0314 |
Toxoplasma gondii | ABC1 family protein | 0.007 | 0.1174 | 0.5 |
Echinococcus granulosus | tar DNA binding protein | 0.0061 | 0.0963 | 0.1091 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.007 | 0.1174 | 0.1531 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.007 | 0.1174 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.007 | 0.1174 | 0.5 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.01 | 0.1875 | 0.2447 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0277 | 0.0361 |
Trichomonas vaginalis | esterase, putative | 0.007 | 0.1174 | 0.5 |
Brugia malayi | beta-lactamase | 0.007 | 0.1174 | 0.4919 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.007 | 0.1174 | 0.5 |
Mycobacterium ulcerans | lipase LipD | 0.007 | 0.1174 | 0.5 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.007 | 0.1174 | 0.5 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0032 | 0.0277 | 0.1161 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.01 | 0.1878 | 0.7872 |
Brugia malayi | TAR-binding protein | 0.0061 | 0.0963 | 0.4036 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.01 | 0.1878 | 0.7872 |
Onchocerca volvulus | 0.007 | 0.1174 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1174 | 0.4919 |
Brugia malayi | beta-lactamase family protein | 0.007 | 0.1174 | 0.4919 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1174 | 0.4919 |
Loa Loa (eye worm) | RNA binding protein | 0.0061 | 0.0963 | 0.4036 |
Mycobacterium leprae | Probable lipase LipE | 0.007 | 0.1174 | 0.5 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.007 | 0.1174 | 0.5 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.01 | 0.1875 | 0.2297 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.007 | 0.1174 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0963 | 0.1256 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.007 | 0.1174 | 0.1531 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0122 | 0.2386 | 1 |
Echinococcus granulosus | geminin | 0.0349 | 0.7665 | 0.868 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0122 | 0.2386 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0349 | 0.7665 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0349 | 0.7665 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0277 | 0.0314 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0277 | 0.0339 |
Onchocerca volvulus | 0.007 | 0.1174 | 1 | |
Plasmodium vivax | hypothetical protein, conserved | 0.007 | 0.1174 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.1137 | 0.4766 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.1875 | 0.786 |
Leishmania major | hypothetical protein, conserved | 0.007 | 0.1174 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0277 | 0.0361 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0963 | 0.1256 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0277 | 0.0361 |
Echinococcus multilocularis | FTZ F1 alpha | 0.01 | 0.1875 | 0.2297 |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.1137 | 0.1483 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0963 | 0.1256 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.01 | 0.1875 | 0.786 |
Schistosoma mansoni | hypothetical protein | 0.008 | 0.1411 | 0.1841 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0061 | 0.0963 | 0.4036 |
Mycobacterium ulcerans | beta-lactamase | 0.007 | 0.1174 | 0.5 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.007 | 0.1174 | 0.4919 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.01 | 0.1875 | 0.2124 |
Trypanosoma brucei | hypothetical protein, conserved | 0.007 | 0.1174 | 0.5 |
Echinococcus granulosus | FTZ F1 alpha | 0.0399 | 0.883 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0061 | 0.0963 | 0.1256 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0277 | 0.0361 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.007 | 0.1174 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1174 | 0.4919 |
Echinococcus multilocularis | tar DNA binding protein | 0.0061 | 0.0963 | 0.118 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0032 | 0.0277 | 0.1161 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0277 | 0.0339 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.