Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.8655 | 0.5 |
Onchocerca volvulus | 0.0028 | 1 | 0.5 | |
Echinococcus granulosus | lamin dm0 | 0.0028 | 1 | 0.5 |
Echinococcus multilocularis | musashi | 0.0028 | 1 | 0.5 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.8655 | 0.5 |
Schistosoma mansoni | intermediate filament proteins | 0.0028 | 1 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.8655 | 0.5 |
Schistosoma mansoni | lamin | 0.0028 | 1 | 0.5 |
Schistosoma mansoni | lamin | 0.0028 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.9606 | 0.9606 |
Brugia malayi | hypothetical protein | 0.0017 | 0.1499 | 0.1499 |
Brugia malayi | hypothetical protein | 0.0026 | 0.8655 | 0.8655 |
Echinococcus granulosus | lamin | 0.0028 | 1 | 0.5 |
Onchocerca volvulus | 0.0028 | 1 | 0.5 | |
Echinococcus multilocularis | lamin | 0.0028 | 1 | 0.5 |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 1 | 0.5 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 1 | 1 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 1 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 1 | 0.5 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.8655 | 0.5 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.8655 | 0.5 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.8655 | 0.5 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.8655 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.8655 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.8655 | 0.8655 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.