Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0081 | 0.4362 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.4362 | 0.4362 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0081 | 0.4362 | 0.4362 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0081 | 0.4362 | 0.4362 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0081 | 0.4362 | 0.4362 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0081 | 0.4362 | 0.4362 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0081 | 0.4362 | 0.4362 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0081 | 0.4362 | 0.4362 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.4362 | 0.4362 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0081 | 0.4362 | 0.4362 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0081 | 0.4362 | 0.4362 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0081 | 0.4362 | 0.4362 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.4362 | 0.4362 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.4362 | 0.4362 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0081 | 0.4362 | 0.4362 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0081 | 0.4362 | 0.4362 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0131 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0081 | 0.4362 | 0.4362 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0081 | 0.4362 | 0.4362 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0081 | 0.4362 | 0.4362 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0131 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0081 | 0.4362 | 0.4362 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0081 | 0.4362 | 0.4362 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0081 | 0.4362 | 0.4362 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0081 | 0.4362 | 0.4362 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0081 | 0.4362 | 0.4362 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0081 | 0.4362 | 0.4362 |
Schistosoma mansoni | thyroid hormone receptor | 0.0081 | 0.4362 | 0.4362 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0081 | 0.4362 | 0.4362 |
Loa Loa (eye worm) | hypothetical protein | 0.0131 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0131 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0131 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0131 | 1 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0131 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0081 | 0.4362 | 0.4362 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0081 | 0.4362 | 0.4362 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.4362 | 0.4362 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0081 | 0.4362 | 0.4362 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0081 | 0.4362 | 0.4362 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0081 | 0.4362 | 0.4362 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0081 | 0.4362 | 0.4362 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0081 | 0.4362 | 0.4362 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0081 | 0.4362 | 0.4362 |
Brugia malayi | steroid hormone receptor | 0.0081 | 0.4362 | 0.4362 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.4362 | 0.4362 |
Echinococcus granulosus | FTZ F1 alpha | 0.0081 | 0.4362 | 0.4362 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0081 | 0.4362 | 0.4362 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0081 | 0.4362 | 0.5 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0081 | 0.4362 | 0.4362 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0081 | 0.4362 | 0.4362 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0081 | 0.4362 | 0.4362 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0081 | 0.4362 | 0.4362 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0081 | 0.4362 | 0.4362 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.4362 | 0.4362 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.4362 | 0.4362 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0081 | 0.4362 | 0.4362 |
Schistosoma mansoni | nuclear hormone receptor | 0.0081 | 0.4362 | 0.4362 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0081 | 0.4362 | 0.4362 |
Echinococcus granulosus | acetylcholinesterase | 0.0131 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0081 | 0.4362 | 0.4362 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0081 | 0.4362 | 0.4362 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0081 | 0.4362 | 0.4362 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0081 | 0.4362 | 0.4362 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0081 | 0.4362 | 0.4362 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0081 | 0.4362 | 0.4362 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0081 | 0.4362 | 0.5 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0081 | 0.4362 | 0.4362 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0081 | 0.4362 | 0.4362 |
Brugia malayi | nuclear hormone receptor | 0.0081 | 0.4362 | 0.4362 |
Echinococcus granulosus | acetylcholinesterase | 0.0131 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0131 | 1 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0081 | 0.4362 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0081 | 0.4362 | 0.4362 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0081 | 0.4362 | 0.4362 |
Brugia malayi | ecdysteroid receptor | 0.0081 | 0.4362 | 0.4362 |
Schistosoma mansoni | coup transcription factor | 0.0081 | 0.4362 | 0.4362 |
Loa Loa (eye worm) | carboxylesterase | 0.0131 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0131 | 1 | 1 |
Brugia malayi | nuclear receptor NHR-88 | 0.0081 | 0.4362 | 0.4362 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0081 | 0.4362 | 0.4362 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0081 | 0.4362 | 0.4362 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0081 | 0.4362 | 0.4362 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0081 | 0.4362 | 0.4362 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.