Detailed information for compound 619510

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 347.432 | Formula: C17H21N3O3S
  • H donors: 1 H acceptors: 3 LogP: 1.62 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC/N=C\1/SC(C(=O)N1CC)CC(=O)Nc1ccc(cc1)C(=O)C
  • InChi: 1S/C17H21N3O3S/c1-4-18-17-20(5-2)16(23)14(24-17)10-15(22)19-13-8-6-12(7-9-13)11(3)21/h6-9,14H,4-5,10H2,1-3H3,(H,19,22)/b18-17+
  • InChiKey: XAAPWLPKAVIJAU-ISLYRVAYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica hypothetical protein 0.0132 0.0348 0.3126
Onchocerca volvulus 0.0713 0.2058 0.9196
Entamoeba histolytica cysteine protease, putative 0.023 0.0637 0.5719
Trypanosoma cruzi major cysteine proteinase, putative 0.012 0.0312 0.0531
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1115 0.5484
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0139 0.0368 0.1809
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.012 0.0312 0.1517
Brugia malayi nuclear receptor RXR 0.0044 0.0087 0.0148
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0022 0.0107
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0017 0.0007 0.0012
Loa Loa (eye worm) runx1 0.0059 0.0134 0.0136
Loa Loa (eye worm) latrophilin receptor protein 2 0.0111 0.0284 0.029
Echinococcus multilocularis nuclear receptor nhr 48 0.0039 0.0073 0.0073
Trypanosoma brucei protein kinase, putative 0.0039 0.0075 0.0367
Brugia malayi hypothetical protein 0.0474 0.1355 0.2306
Schistosoma mansoni hypothetical protein 0.0835 0.242 0.4118
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0816 0.3963
Schistosoma mansoni jumonji/arid domain-containing protein 0.0067 0.0157 0.0267
Brugia malayi Cathepsin L-like precursor 0.0392 0.1115 0.1897
Schistosoma mansoni alpha-glucosidase 0.0142 0.0377 0.0643
Brugia malayi jmjC domain containing protein 0.0017 0.0007 0.0012
Loa Loa (eye worm) hypothetical protein 0.035 0.0989 0.101
Plasmodium vivax serine-repeat antigen (SERA), putative 0.012 0.0312 0.2753
Schistosoma mansoni hypothetical protein 0.0093 0.0231 0.0393
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0066 0.0596
Echinococcus granulosus cathepsin L 0.023 0.0637 0.0637
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.012 0.0312 0.0531
Echinococcus granulosus mothers against decapentaplegic 5 0.0024 0.0028 0.0028
Echinococcus multilocularis dnaJ subfamily B 0.0835 0.242 0.242
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0025 0.0031 0.0053
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0018 0.0011 0.0011
Mycobacterium tuberculosis Conserved protein 0.0025 0.0031 0.0738
Echinococcus multilocularis cathepsin L 0.023 0.0637 0.0637
Echinococcus granulosus tar DNA binding protein 0.0241 0.0667 0.0667
Trichomonas vaginalis ran, putative 0.0031 0.0051 0.0246
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0083 0.0202 0.0344
Plasmodium vivax hypothetical protein, conserved 0.0025 0.0031 0.0219
Leishmania major 4-coumarate:coa ligase-like protein 0.0015 0.0001 0.0006
Giardia lamblia Cathepsin L precursor 0.012 0.0312 0.1535
Mycobacterium leprae Probable lipase LipE 0.0025 0.0031 0.0799
Echinococcus granulosus cysteine protease 0.023 0.0637 0.0637
Toxoplasma gondii isocitrate dehydrogenase 0.0023 0.0025 0.0088
Brugia malayi RNA, U transporter 1 0.0121 0.0315 0.0536
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0023 0.0025 0.0122
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0011 0.0011
Echinococcus multilocularis survival motor neuron protein 1 0.0173 0.0468 0.0468
Brugia malayi Cathepsin L-like precursor 0.0392 0.1115 0.1897
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0039 0.0073 0.0125
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0024 0.0028 0.0048
Brugia malayi Bromodomain containing protein 0.0039 0.0073 0.0124
Entamoeba histolytica cysteine protease, putative 0.023 0.0637 0.5719
Brugia malayi nuclear receptor RXR 0.0039 0.0073 0.0125
Echinococcus multilocularis lysine specific demethylase 5A 0.0062 0.0141 0.0141
Brugia malayi Papain family cysteine protease containing protein 0.0392 0.1115 0.1897
Toxoplasma gondii t-complex protein beta subunit 0.0017 0.0007 0.0002
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0023 0.0025 0.0025
Brugia malayi Cathepsin L-like precursor 0.0392 0.1115 0.1897
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0066 0.0323
Mycobacterium tuberculosis Probable hydrolase 0.0025 0.0031 0.0738
Trypanosoma cruzi cysteine peptidase, putative 0.023 0.0637 0.1085
Echinococcus multilocularis mothers against decapentaplegic 5 0.0024 0.0028 0.0028
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0012 0.0059
Schistosoma mansoni smad1 5 8 and 0.0024 0.0028 0.0048
Loa Loa (eye worm) hypothetical protein 0.0224 0.0617 0.063
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0039 0.0073 0.0075
Mycobacterium tuberculosis Conserved protein 0.0025 0.0031 0.0738
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0083 0.0202 0.0206
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.008 0.0136
Brugia malayi Pre-SET motif family protein 0.0626 0.1803 0.3069
Onchocerca volvulus Cathepsin F homolog 0.0392 0.1115 0.4979
Giardia lamblia Fructose-bisphosphate aldolase 0.0291 0.0816 0.4012
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.002 0.002
Giardia lamblia Cathepsin L precursor 0.012 0.0312 0.1535
Giardia lamblia Dipeptidyl-peptidase I precursor 0.012 0.0312 0.1535
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0004 0.0019
Echinococcus multilocularis chromobox protein 1 0.0051 0.0109 0.0109
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0066 0.0323
Echinococcus granulosus mixed lineage leukemia protein mll 0.0018 0.0011 0.0011
Echinococcus multilocularis tar DNA binding protein 0.0241 0.0667 0.0667
Trichomonas vaginalis CAMK family protein kinase 0.0035 0.006 0.0293
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1115 0.5484
Trypanosoma cruzi major cysteine proteinase, putative 0.012 0.0312 0.0531
Entamoeba histolytica cysteine protease, putative 0.023 0.0637 0.5719
Schistosoma mansoni coup transcription factor 0.0083 0.0202 0.0344
Trypanosoma cruzi cysteine peptidase, putative 0.0392 0.1115 0.1897
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0039 0.0075 0.0127
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0036 0.0176
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.012 0.0312 0.1517
Giardia lamblia Dipeptidyl-peptidase I precursor 0.012 0.0312 0.1535
Brugia malayi cathepsin L-like cysteine proteinase 0.012 0.0312 0.0531
Loa Loa (eye worm) hypothetical protein 0.011 0.0284 0.029
Loa Loa (eye worm) hypothetical protein 0.012 0.0312 0.0319
Echinococcus granulosus dnaJ subfamily B 0.0835 0.242 0.242
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0392 0.1115 0.1138
Brugia malayi RNA recognition motif domain containing protein 0.0241 0.0667 0.1136
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.023 0.0637 0.1085
Plasmodium vivax unspecified product 0.023 0.0637 0.5691
Schistosoma mansoni cathepsin S (C01 family) 0.012 0.0312 0.0531
Echinococcus multilocularis protein dispatched 1 0.011 0.0281 0.0281
Brugia malayi Heterochromatin protein 1 0.0051 0.0109 0.0185
Trichomonas vaginalis D-aminoacylase, putative 0.0025 0.0031 0.0152
Loa Loa (eye worm) hypothetical protein 0.0083 0.0203 0.0208
Echinococcus multilocularis smoothened 0.3408 1 1
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0039 0.0073 0.0073
Schistosoma mansoni jumonji domain containing protein 0.0092 0.0229 0.0389
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.023 0.0637 0.1085
Echinococcus granulosus secreted frizzled protein 0.007 0.0166 0.0166
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0098 0.0248 0.0422
Leishmania major 4-coumarate:coa ligase-like protein 0.0015 0.0001 0.0006
Plasmodium vivax unspecified product 0.011 0.0284 0.2498
Trichomonas vaginalis chromobox protein, putative 0.0031 0.0049 0.0238
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0039 0.0073 0.0125
Schistosoma mansoni ap endonuclease 0.0018 0.0012 0.0021
Onchocerca volvulus 0.0059 0.0131 0.0581
Trypanosoma brucei DNA polymerase eta, putative 0.0033 0.0055 0.027
Echinococcus granulosus frizzled 0.0154 0.0411 0.0411
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0012 0.0012
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0111 0.0284 0.0284
Brugia malayi beta-lactamase family protein 0.0025 0.0031 0.0053
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.012 0.0312 0.2753
Echinococcus multilocularis tumor protein p63 0.0261 0.0729 0.0729
Entamoeba histolytica hypothetical protein 0.0132 0.0348 0.3126
Entamoeba histolytica cysteine protease, putative 0.023 0.0637 0.5719
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0083 0.0202 0.0202
Mycobacterium ulcerans beta-lactamase 0.0025 0.0031 0.0757
Trypanosoma cruzi cruzipain precursor, putative 0.0392 0.1115 0.1897
Mycobacterium tuberculosis Probable esterase LipL 0.0025 0.0031 0.0738
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0035 0.006 0.0292
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0075
Echinococcus granulosus transcription factor Dp 1 0.0024 0.003 0.003
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0023 0.0025 0.0025
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0059 0.0132 0.0651
Leishmania major hypothetical protein, conserved 0.0016 0.0004 0.002
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0009 0.0009
Loa Loa (eye worm) T-complex protein 1 0.0017 0.0007 0.0008
Brugia malayi hypothetical protein 0.0124 0.0325 0.0552
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0015 0.0001 0.0032
Brugia malayi chromobox protein homolog 3 0.0029 0.0043 0.0073
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0042 0.0082 0.0406
Trichomonas vaginalis importin beta-1, putative 0.0035 0.006 0.0292
Trypanosoma cruzi cysteine protease, putative 0.023 0.0637 0.1085
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.012 0.0312 0.1517
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.011 0.0284 0.0483
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0392 0.1115 0.5417
Loa Loa (eye worm) Smad1 0.0024 0.0028 0.0029
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.0242 0.0242
Echinococcus granulosus frizzled 0.0154 0.0411 0.0411
Loa Loa (eye worm) hypothetical protein 0.3338 0.9792 1
Schistosoma mansoni zinc finger protein 0.0016 0.0004 0.0007
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.0028 0.0029
Echinococcus granulosus cathepsin b 0.2008 0.5875 0.5875
Brugia malayi MAP kinase sur-1 0.0039 0.0075 0.0127
Brugia malayi Latrophilin receptor protein 2 0.0111 0.0284 0.0484
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0032
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.012 0.0312 0.1517
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0039 0.0073 0.0322
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0816 0.3963
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0282 0.0789 0.3836
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.012 0.0312 0.0531
Onchocerca volvulus 0.0099 0.0251 0.1116
Loa Loa (eye worm) hypothetical protein 0.0282 0.0789 0.0806
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0392 0.1115 0.5417
Echinococcus multilocularis neuropeptide receptor A26 0.0607 0.1747 0.1747
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0024 0.0028 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.012 0.0312 0.1517
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0009 0.0016
Brugia malayi hypothetical protein 0.0774 0.2238 0.3809
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.2008 0.5875 1
Plasmodium falciparum phd finger protein, putative 0.0021 0.0021 0.0128
Giardia lamblia Encystation-specific protease 0.012 0.0312 0.1535
Echinococcus granulosus survival motor neuron protein 1 0.0173 0.0468 0.0468
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0015 0.0001 0.0031
Schistosoma mansoni nuclear receptor 0.0039 0.0073 0.0125
Schistosoma mansoni thyroid hormone receptor 0.0083 0.0202 0.0344
Loa Loa (eye worm) hypothetical protein 0.0098 0.0248 0.0253
Brugia malayi MH2 domain containing protein 0.0024 0.0028 0.0048
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0025 0.0031 0.0053
Brugia malayi Nuclear hormone receptor E75 0.0039 0.0073 0.0125
Schistosoma mansoni tar DNA-binding protein 0.0241 0.0667 0.1136
Leishmania major DNA polymerase eta, putative 0.0023 0.0026 0.0129
Loa Loa (eye worm) MBCTL1 0.0098 0.0248 0.0253
Echinococcus granulosus frizzled 0.0154 0.0411 0.0411
Loa Loa (eye worm) hypothetical protein 0.012 0.0312 0.0319
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0139 0.0368 0.1809
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0096 0.0242 0.0412
Schistosoma mansoni hypothetical protein 0.0621 0.1787 0.3041
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0083 0.0202 0.0344
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0012 0.006
Echinococcus granulosus Protein patched homolog 1 0.0096 0.0241 0.0241
Giardia lamblia Kinase, PLK 0.007 0.0163 0.0803
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.012 0.0312 0.0319
Brugia malayi nuclear hormone receptor 0.0039 0.0073 0.0125
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0392 0.1115 0.5417
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0022 0.0107
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0242 0.0412
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0132 0.3195
Echinococcus multilocularis transcription factor Dp 1 0.0024 0.003 0.003
Echinococcus granulosus chromobox protein 1 0.0051 0.0109 0.0109
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.012 0.0312 0.2753
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0017 0.0007 0.0013
Echinococcus granulosus importin subunit beta 1 0.0043 0.0084 0.0084
Trichomonas vaginalis CAMK family protein kinase 0.007 0.0163 0.0793
Plasmodium falciparum importin beta, putative 0.0043 0.0084 0.0692
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.012 0.0312 0.2753
Loa Loa (eye worm) hypothetical protein 0.0072 0.017 0.0173
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.012 0.0312 0.2753
Brugia malayi nuclear hormone receptor family member odr-7 0.0039 0.0073 0.0125
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0091 0.0226 0.0226
Giardia lamblia Cathepsin B precursor 0.0704 0.2033 1
Brugia malayi cathepsin L precursor 0.012 0.0312 0.0531
Echinococcus granulosus polycomb protein SCMH1 0.0086 0.0213 0.0213
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.012 0.0312 0.0531
Leishmania major cathepsin L-like protease 0.0392 0.1115 0.5484
Trypanosoma brucei hypothetical protein, conserved 0.0025 0.0031 0.0154
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.012 0.0312 0.2753
Schistosoma mansoni thyroid hormone receptor 0.0083 0.0202 0.0344
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0012 0.0021
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0044 0.0087 0.0087
Schistosoma mansoni cathepsin C 0.012 0.0312 0.0531
Schistosoma mansoni hypothetical protein 0.0083 0.0203 0.0346
Echinococcus granulosus ecdysone induced protein 78C 0.0083 0.0202 0.0202
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0066 0.0323
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0083 0.0202 0.0897
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0039 0.0073 0.0073
Brugia malayi hypothetical protein 0.0132 0.0348 0.0593
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0816 0.3963
Trypanosoma cruzi cysteine peptidase, putative 0.0392 0.1115 0.1897
Brugia malayi Cathepsin L-like precursor 0.0392 0.1115 0.1897
Onchocerca volvulus 0.0025 0.0031 0.0134
Giardia lamblia Cathepsin B precursor 0.012 0.0312 0.1535
Brugia malayi cathepsin F-like cysteine proteinase 0.011 0.0284 0.0483
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0075
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0083 0.0202 0.0344
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0083 0.0202 0.0344
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0015 0.0001 0.0032
Toxoplasma gondii ABC1 family protein 0.0025 0.0031 0.012
Loa Loa (eye worm) hypothetical protein 0.011 0.0284 0.029
Leishmania major 4-coumarate:coa ligase-like protein 0.0015 0.0001 0.0006
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0066 0.0066
Echinococcus granulosus cathepsin L 0.012 0.0312 0.0312
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0018 0.0088
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0035 0.006 0.0292
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0032
Schistosoma mansoni importin beta-1 0.0043 0.0084 0.0143
Loa Loa (eye worm) hypothetical protein 0.0083 0.0202 0.0206
Echinococcus multilocularis importin subunit beta 1 0.0043 0.0084 0.0084
Echinococcus granulosus neuropeptide receptor A26 0.0607 0.1747 0.1747
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2399 0.7027 0.7027
Leishmania major T-complex protein 1, beta subunit, putative 0.0017 0.0007 0.0037
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Schistosoma mansoni nuclear receptor 0.0039 0.0073 0.0125
Brugia malayi Niemann-Pick C1 protein precursor 0.0224 0.0617 0.1051
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0043 0.0207
Echinococcus granulosus expressed conserved protein 0.021 0.0577 0.0577
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0031 0.0051 0.0051
Plasmodium vivax vivapain-2 0.0392 0.1115 1
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0023 0.0025 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0392 0.1115 0.5417
Echinococcus multilocularis protein patched 0.0096 0.0241 0.0241
Brugia malayi Importin beta-1 subunit 0.0043 0.0084 0.0143
Plasmodium falciparum serine repeat antigen 3 0.012 0.0312 0.2753
Brugia malayi Fz domain containing protein 0.007 0.0166 0.0282
Trichomonas vaginalis CAMK family protein kinase 0.007 0.0163 0.0793
Trypanosoma cruzi hypothetical protein, conserved 0.0025 0.0031 0.0053
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0075
Schistosoma mansoni cathepsin F (C01 family) 0.0392 0.1115 0.1897
Mycobacterium ulcerans esterase/lipase LipP 0.0025 0.0031 0.0757
Echinococcus granulosus SAM and MBT domain containing protein 0.0086 0.0213 0.0213
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0816 0.3963
Schistosoma mansoni cathepsin s 0.011 0.0284 0.0483
Schistosoma mansoni nuclear hormone receptor 0.0039 0.0073 0.0125
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.012 0.0312 0.1517
Loa Loa (eye worm) hypothetical protein 0.0474 0.1355 0.1384
Echinococcus multilocularis secreted frizzled protein 0.007 0.0166 0.0166
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0011 0.0011
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0023 0.0025 0.0122
Brugia malayi Cathepsin L-like cysteine proteinase 0.0282 0.0789 0.1344
Brugia malayi isocitrate dehydrogenase 0.0023 0.0025 0.0042
Loa Loa (eye worm) hypothetical protein 0.0392 0.1115 0.1138
Echinococcus granulosus dna polymerase eta 0.0033 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.011 0.0284 0.029
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0032
Echinococcus multilocularis chromobox protein 1 0.0051 0.0109 0.0109
Schistosoma mansoni intermediate filament proteins 0.002 0.0018 0.0031
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0032
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0001 0.0002
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2008 0.5875 1
Loa Loa (eye worm) isocitrate dehydrogenase 0.0023 0.0025 0.0025
Plasmodium falciparum cysteine proteinase falcipain 1 0.023 0.0637 0.5691
Schistosoma mansoni cathepsin F (C01 family) 0.0392 0.1115 0.1897
Schistosoma mansoni ran 0.0031 0.0051 0.0086
Loa Loa (eye worm) hypothetical protein 0.012 0.0312 0.0319
Schistosoma mansoni kinase 0.0036 0.0063 0.0107
Echinococcus multilocularis cathepsin L cysteine protease 0.0392 0.1115 0.1115
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0021 0.0022
Echinococcus granulosus thyroid hormone receptor alpha 0.0039 0.0073 0.0073
Onchocerca volvulus Huntingtin homolog 0.0124 0.0325 0.1445
Entamoeba histolytica papain family cysteine protease domain containing protein 0.012 0.0312 0.2799
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2008 0.5875 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0083 0.0202 0.0344
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0012 0.0046
Onchocerca volvulus 0.002 0.0018 0.0076
Trichomonas vaginalis D-aminoacylase, putative 0.0025 0.0031 0.0152
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0022 0.0107
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0132 0.0348 0.0348
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.012 0.0312 0.1517
Entamoeba histolytica cysteine proteinase, putative 0.0392 0.1115 1
Trypanosoma cruzi cysteine peptidase, putative 0.0392 0.1115 0.1897
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2008 0.5875 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0083 0.0202 0.0344
Onchocerca volvulus Huntingtin homolog 0.0124 0.0325 0.1445
Trichomonas vaginalis CAMK family protein kinase 0.007 0.0163 0.0793
Giardia lamblia Cathepsin L precursor 0.012 0.0312 0.1535
Leishmania major cathepsin L-like protease 0.0392 0.1115 0.5484
Giardia lamblia Cathepsin B precursor 0.012 0.0312 0.1535
Entamoeba histolytica cysteine protease, putative 0.012 0.0312 0.2799
Echinococcus multilocularis GPCR, family 2 0.0111 0.0284 0.0284
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0023 0.0025 0.0161
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0023 0.0025 0.0042
Loa Loa (eye worm) hypothetical protein 0.0044 0.0087 0.0089
Plasmodium falciparum serine repeat antigen 1 0.012 0.0312 0.2753
Toxoplasma gondii cathepsin CPL 0.0392 0.1115 0.5469
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0017 0.0007 0.0007
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.0036 0.0036
Brugia malayi serine/threonine-protein kinase plk-2 0.007 0.0163 0.0278
Echinococcus multilocularis zinc finger protein 0.0023 0.0027 0.0027
Trypanosoma cruzi ISWI complex protein 0.0016 0.0004 0.0007
Giardia lamblia Cathepsin L precursor 0.012 0.0312 0.1535
Schistosoma mansoni frizzled-like receptor 0.0083 0.0203 0.0346
Echinococcus granulosus Nuclear hormone receptor HR96 0.0039 0.0073 0.0073
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0022 0.0023 0.0023
Schistosoma mansoni survival motor neuron protein 0.0035 0.0062 0.0106
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0022 0.0107
Echinococcus granulosus cathepsin l1 0.0282 0.0789 0.0789
Echinococcus multilocularis Niemann Pick C1 protein 0.032 0.09 0.09
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.007 0.0163 0.0803
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0075
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0086 0.0213 0.0213
Echinococcus multilocularis polycomb protein SCMH1 0.0086 0.0213 0.0213
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0031 0.0051 0.0215
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0066 0.0066
Trichomonas vaginalis CMGC family protein kinase 0.0039 0.0075 0.0363
Brugia malayi nuclear receptor NHR-88 0.0039 0.0073 0.0125
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0012 0.0295
Echinococcus multilocularis PHD finger protein rhinoceros 0.0021 0.0021 0.0021
Onchocerca volvulus Bile acid receptor homolog 0.0083 0.0202 0.0897
Toxoplasma gondii cathepsin CPC2 0.012 0.0312 0.1506
Echinococcus multilocularis geminin 0.0621 0.1787 0.1787
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0007
Plasmodium falciparum serine repeat antigen 5 0.012 0.0312 0.2753
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1115 0.5484
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0018
Echinococcus multilocularis frizzled 0.0154 0.0411 0.0411
Schistosoma mansoni phd/f-box containing protein 0.0017 0.0007 0.0012
Onchocerca volvulus Cathepsin L homolog 0.0392 0.1115 0.4979
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0132 0.3195
Brugia malayi Papain family cysteine protease containing protein 0.012 0.0312 0.0531
Entamoeba histolytica cysteine protease, putative 0.012 0.0312 0.2799
Echinococcus granulosus serine:threonine protein kinase PLK1 0.007 0.0163 0.0163
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0075
Schistosoma mansoni steroid hormone receptor ad4bp 0.0083 0.0202 0.0344
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0039 0.0073 0.0073
Schistosoma mansoni transcription factor btf3 0.0026 0.0036 0.0062
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0012 0.0059
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0001 0.0005
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0001 0.0032
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0242 0.0412
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.0028 0.0029
Plasmodium falciparum T-complex protein 1 subunit beta 0.0017 0.0007 0.0003
Giardia lamblia PHD finger protein 15 0.0021 0.0021 0.0105
Brugia malayi MH2 domain containing protein 0.0348 0.0983 0.1674
Loa Loa (eye worm) hypothetical protein 0.0118 0.0305 0.0311
Onchocerca volvulus 0.0392 0.1115 0.4979
Echinococcus multilocularis mitogen activated protein kinase 0.0039 0.0075 0.0075
Brugia malayi mbt repeat family protein 0.0086 0.0213 0.0362
Schistosoma mansoni RAR-like nuclear receptor 0.0083 0.0202 0.0344
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0083 0.0202 0.0344
Entamoeba histolytica Ran family GTPase 0.0031 0.0051 0.0454
Loa Loa (eye worm) hypothetical protein 0.0173 0.0468 0.0478
Trichomonas vaginalis CMGC family protein kinase 0.0039 0.0075 0.0363
Onchocerca volvulus 0.0039 0.0073 0.0322
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0132 0.0225
Loa Loa (eye worm) hypothetical protein 0.0282 0.0789 0.0806
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0066 0.0323
Trichomonas vaginalis penicillin-binding protein, putative 0.0025 0.0031 0.0152
Brugia malayi T-complex protein 1, beta subunit 0.0017 0.0007 0.0013
Loa Loa (eye worm) TAR-binding protein 0.0241 0.0667 0.0682
Echinococcus multilocularis microtubule associated protein 2 0.0521 0.1494 0.1494
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.0036 0.0036
Brugia malayi cahepsin L-like non-peptiedase homolog 0.012 0.0312 0.0531
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.012 0.0312 0.1517
Trypanosoma cruzi cysteine proteinase, putative 0.023 0.0637 0.1085
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0007 0.0012
Echinococcus multilocularis sterol regulatory element binding protein 0.0096 0.0241 0.0241
Echinococcus multilocularis secreted frizzled protein 5 0.007 0.0166 0.0166
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0098 0.0248 0.0248
Loa Loa (eye worm) jmjC domain-containing protein 0.0044 0.0088 0.009
Trichomonas vaginalis CAMK family protein kinase 0.007 0.0163 0.0793
Brugia malayi beta-lactamase family protein 0.0025 0.0031 0.0053
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0017 0.0007 0.0035
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0031 0.0049 0.0213
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0291 0.0816 0.7316
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0035 0.0062 0.0106
Brugia malayi hypothetical protein 0.0044 0.0087 0.0148
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1115 0.5484
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0086 0.0213 0.0946
Loa Loa (eye worm) hypothetical protein 0.0124 0.0325 0.0331
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.012 0.0312 0.1517
Brugia malayi ImpB/MucB/SamB family protein 0.0033 0.0055 0.0094
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0031 0.0051 0.0052
Echinococcus granulosus secreted frizzled protein 5 0.007 0.0166 0.0166
Echinococcus multilocularis Niemann Pick C1 protein 0.0224 0.0617 0.0617
Schistosoma mansoni ran 0.0031 0.0051 0.0086
Leishmania major hypothetical protein, conserved 0.0017 0.0007 0.0035
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.012 0.0312 0.2753
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0064 0.0147 0.0147
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0392 0.1115 0.5417
Loa Loa (eye worm) hypothetical protein 0.012 0.0312 0.0319
Echinococcus multilocularis lysine specific demethylase 6a 0.0017 0.0007 0.0007
Onchocerca volvulus Cathepsin L homolog 0.0392 0.1115 0.4979
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0059 0.0132 0.0132
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0022 0.0023 0.0023
Schistosoma mansoni patched 1 0.0096 0.0241 0.041
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.012 0.0312 0.1517
Trypanosoma cruzi transcription factor btf3, putative 0.0026 0.0036 0.0062
Onchocerca volvulus 0.012 0.0312 0.139
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.0107 0.0181
Echinococcus multilocularis transcription factor btf3 0.0026 0.0036 0.0036
Echinococcus granulosus cathepsin l cysteine peptidase 0.0392 0.1115 0.1115
Trypanosoma cruzi importin beta-1 subunit, putative 0.0035 0.006 0.0102
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0392 0.1115 0.5417
Echinococcus granulosus geminin 0.0621 0.1787 0.1787
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1115 0.5484
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0001 0.0032
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0344 0.0972 0.0972
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0392 0.1115 0.1115
Brugia malayi jmjC domain containing protein 0.0017 0.0007 0.0012
Loa Loa (eye worm) fibroinase 0.0392 0.1115 0.1138
Onchocerca volvulus 0.0025 0.0031 0.0134
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0344 0.0972 0.0972
Loa Loa (eye worm) hypothetical protein 0.0022 0.0024 0.0025
Loa Loa (eye worm) hypothetical protein 0.0038 0.0071 0.0073
Echinococcus multilocularis beta LACTamase domain containing family member 0.0025 0.0031 0.0031
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0044 0.0087 0.0148
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0294 0.0823 0.4051
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0816 0.3963
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0083 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0083 0.0202 0.0206
Brugia malayi mbt repeat family protein 0.0086 0.0213 0.0362
Trypanosoma cruzi polo-like protein kinase, putative 0.007 0.0163 0.0278
Echinococcus multilocularis jumonji domain containing 1A 0.0017 0.0007 0.0007
Brugia malayi orphan nuclear receptor NR2E1 0.0039 0.0073 0.0125
Echinococcus granulosus zinc finger protein 0.0023 0.0027 0.0027
Echinococcus granulosus beta LACTamase domain containing family member 0.0025 0.0031 0.0031
Schistosoma mansoni myelin transcription factor 1 myt1 0.0098 0.0248 0.0422
Loa Loa (eye worm) hypothetical protein 0.0047 0.0096 0.0098
Echinococcus multilocularis jumonji domain containing protein 0.003 0.0046 0.0046
Loa Loa (eye worm) histone methyltransferase 0.0021 0.0022 0.0022
Giardia lamblia Kinase, CMGC MAPK 0.0039 0.0075 0.0367
Loa Loa (eye worm) beta-lactamase 0.0025 0.0031 0.0032
Echinococcus multilocularis phd:f box containing protein 0.0017 0.0007 0.0007
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.0242 0.0242
Schistosoma mansoni hypothetical protein 0.0529 0.1516 0.258
Echinococcus multilocularis dna polymerase eta 0.0033 0.0055 0.0055
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.012 0.0312 0.2753
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0086 0.0213 0.0362
Schistosoma mansoni hypothetical protein 0.0016 0.0004 0.0007
Loa Loa (eye worm) ICD-1 protein 0.0026 0.0036 0.0037
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0012 0.0288
Toxoplasma gondii PHD-finger domain-containing protein 0.0021 0.0021 0.007
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0042 0.0082 0.0739
Echinococcus granulosus chromobox protein 1 0.0051 0.0109 0.0109
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.012 0.0312 0.0531
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0012 0.0046
Onchocerca volvulus 0.0282 0.0789 0.3524
Onchocerca volvulus 0.0038 0.0071 0.0312
Echinococcus multilocularis muscleblind protein 1 0.0305 0.0857 0.0857
Brugia malayi cathepsin L-like precursor 0.0282 0.0789 0.1344
Schistosoma mansoni hypothetical protein 0.0111 0.0284 0.0484
Trypanosoma cruzi hypothetical protein, conserved 0.0025 0.0031 0.0053
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.007 0.0163 0.0167
Plasmodium vivax vivapain-1 0.023 0.0637 0.5691
Giardia lamblia Cathepsin B precursor 0.012 0.0312 0.1535
Plasmodium falciparum cysteine proteinase falcipain 3 0.0392 0.1115 1
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0039 0.0075 0.0127
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0392 0.1115 0.1115
Brugia malayi T-complex protein 1, beta subunit 0.0017 0.0007 0.0013
Brugia malayi intermediate filament protein 0.002 0.0018 0.0031
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0039 0.0075 0.0367
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0021 0.0022 0.0022
Echinococcus granulosus cathepsin L cysteine protease 0.023 0.0637 0.0637
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.012 0.0312 0.1517
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0083 0.0202 0.0206
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0066 0.0323
Brugia malayi cathepsin Z-like cysteine proteinase 0.012 0.0312 0.0531
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0025 0.0032 0.0054
Entamoeba histolytica cysteine proteinase 2 0.023 0.0637 0.5719
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0018 0.0088
Brugia malayi jmjC domain containing protein 0.0067 0.0157 0.0267
Brugia malayi nuclear hormone receptor family member nhr-6 0.0039 0.0073 0.0125
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0017 0.0007 0.0036
Loa Loa (eye worm) hypothetical protein 0.0044 0.0087 0.0089
Brugia malayi photoreceptor-specific nuclear receptor 0.0083 0.0202 0.0344
Toxoplasma gondii preprocathepsin c precursor, putative 0.012 0.0312 0.1506
Brugia malayi conserved hypotetical protein 0.0039 0.0073 0.0125
Loa Loa (eye worm) hypothetical protein 0.0096 0.0241 0.0246
Brugia malayi tailless protein 0.0039 0.0073 0.0125
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0132 0.0348 0.0348
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0009 0.0016
Trypanosoma brucei cysteine peptidase C (CPC) 0.0704 0.2033 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0111 0.0284 0.0284
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0012 0.5
Echinococcus multilocularis mitogen activated protein kinase 3 0.0039 0.0075 0.0075
Onchocerca volvulus 0.0774 0.2238 1
Echinococcus multilocularis peregrin 0.0024 0.0028 0.0028
Echinococcus granulosus cathepsin L cysteine proteinase 0.0392 0.1115 0.1115
Loa Loa (eye worm) RNA binding protein 0.0241 0.0667 0.0682
Trypanosoma brucei RNA helicase, putative 0.0069 0.0161 0.0794
Entamoeba histolytica serine/threonine protein kinase, putative 0.007 0.0163 0.1464
Plasmodium falciparum serine repeat antigen 7 0.012 0.0312 0.2753
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0392 0.1115 0.5417
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0096 0.0241 0.0246
Schistosoma mansoni frizzled-like receptor 0.0083 0.0203 0.0346
Entamoeba histolytica cysteine protease, putative 0.012 0.0312 0.2799
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0224 0.0617 0.5537
Loa Loa (eye worm) MH2 domain-containing protein 0.0348 0.0983 0.1004
Schistosoma mansoni transcription factor LCR-F1 0.0132 0.0348 0.0593
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.012 0.0312 0.0531
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0025 0.0031 0.0757
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0023 0.0025 0.0025
Leishmania major hypothetical protein, conserved 0.0025 0.0031 0.0154
Loa Loa (eye worm) hypothetical protein 0.0025 0.0031 0.0032
Trypanosoma cruzi polo-like protein kinase, putative 0.007 0.0163 0.0278
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1115 0.5484
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0039 0.0073 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.012 0.0312 0.1517
Giardia lamblia Cathepsin B precursor 0.0704 0.2033 1
Echinococcus multilocularis cathepsin b 0.2008 0.5875 0.5875
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0704 0.2033 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0392 0.1115 0.5417
Loa Loa (eye worm) ctsf protein 0.0392 0.1115 0.1138
Schistosoma mansoni cathepsin F (C01 family) 0.0282 0.0789 0.1344
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0043 0.0207
Schistosoma mansoni alpha glucosidase 0.0037 0.0066 0.0113
Echinococcus granulosus lamin 0.002 0.0018 0.0018
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0083 0.0202 0.0202
Brugia malayi CHE-14 protein 0.0096 0.0241 0.041
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.012 0.0312 0.2753
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0083 0.0202 0.0344
Entamoeba histolytica cysteine protease, putative 0.012 0.0312 0.2799
Entamoeba histolytica cysteine protease, putative 0.023 0.0637 0.5719
Echinococcus granulosus tumor protein p63 0.0261 0.0729 0.0729
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.012 0.0312 0.1517
Plasmodium vivax vivapain-3 0.023 0.0637 0.5691
Toxoplasma gondii isocitrate dehydrogenase 0.0023 0.0025 0.0088
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0392 0.1115 0.5417
Loa Loa (eye worm) papain family cysteine protease containing protein 0.012 0.0312 0.0319
Brugia malayi Calcitonin receptor-like protein seb-1 0.035 0.0989 0.1683
Schistosoma mansoni hypothetical protein 0.0621 0.1787 0.3041
Trypanosoma brucei importin beta-1 subunit, putative 0.0043 0.0084 0.0412
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0031 0.0051 0.0086
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.012 0.0312 0.2753
Loa Loa (eye worm) hypothetical protein 0.0086 0.0213 0.0217
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0025 0.0031 0.0738
Mycobacterium ulcerans hypothetical protein 0.0015 0.0001 0.0032
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0007 0.0007
Schistosoma mansoni zinc finger protein 0.0039 0.0073 0.0125
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0075
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.0036 0.0061
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0083 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0015 0.0001 0.0001
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0023 0.0026 0.0095
Brugia malayi Frizzled/Smoothened family membrane region containing protein 0.0154 0.0411 0.0699
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0017 0.0007 0.0013
Brugia malayi Cathepsin L-like precursor 0.0282 0.0789 0.1344
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0083 0.0202 0.0202
Brugia malayi cathepsin Z-like cysteine proteinase 0.012 0.0312 0.0531
Echinococcus granulosus cathepsin l1 0.0392 0.1115 0.1115
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0465 0.1327 0.1356
Loa Loa (eye worm) transcription factor SMAD2 0.0348 0.0983 0.1004
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0066 0.0323
Loa Loa (eye worm) frizzled/Smoothened family membrane region containing protein 0.0154 0.0411 0.042
Plasmodium vivax vivapain-2 0.0392 0.1115 1
Brugia malayi latrophilin 2 splice variant baaae 0.0239 0.0663 0.1128
Entamoeba histolytica cysteine proteinase, putative 0.023 0.0637 0.5719
Echinococcus multilocularis ecdysone induced protein 78C 0.0083 0.0202 0.0202
Echinococcus multilocularis snurportin 1 0.0454 0.1297 0.1297
Entamoeba histolytica hypothetical protein 0.0132 0.0348 0.3126
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0392 0.1115 0.5417
Loa Loa (eye worm) papain family cysteine protease containing protein 0.012 0.0312 0.0319
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0036 0.0176
Brugia malayi Nuclear hormone receptor-like 1 0.0044 0.0087 0.0148
Plasmodium falciparum serine repeat antigen 2 0.012 0.0312 0.2753
Leishmania major cathepsin L-like protease 0.0392 0.1115 0.5484
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.0242 0.0242
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0039 0.0073 0.0125
Giardia lamblia Hypothetical protein 0.012 0.0312 0.1535
Schistosoma mansoni hypothetical protein 0.0093 0.0231 0.0393
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0139 0.0368 0.0626
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0064 0.0147 0.0147
Giardia lamblia Cysteine protease 0.012 0.0312 0.1535
Entamoeba histolytica hypothetical protein 0.0035 0.006 0.0539
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0108 0.0277 0.0277
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0017 0.0007 0.0007
Brugia malayi Nuclear hormone receptor-like 1 0.0044 0.0087 0.0148
Giardia lamblia Dipeptidyl-peptidase I precursor 0.012 0.0312 0.1535
Plasmodium falciparum serine repeat antigen 8 0.012 0.0312 0.2753
Brugia malayi PHD-finger family protein 0.0029 0.0043 0.0073
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0017 0.0007 0.0003
Schistosoma mansoni sex comb on midleg homolog 0.0086 0.0213 0.0362
Toxoplasma gondii histone lysine methyltransferase SET1 0.0117 0.0303 0.1459
Mycobacterium tuberculosis Probable lipase LipD 0.0025 0.0031 0.0738
Leishmania major cathepsin L-like protease 0.0392 0.1115 0.5484
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.012 0.0312 0.2753
Loa Loa (eye worm) hypothetical protein 0.0044 0.0087 0.0089
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0106 0.0271 0.0271
Echinococcus multilocularis lysosomal alpha glucosidase 0.0165 0.0445 0.0445
Brugia malayi MH1 domain containing protein 0.0024 0.0028 0.0048
Brugia malayi steroid hormone receptor 0.0083 0.0202 0.0344
Giardia lamblia Cathepsin L-like protease 0.012 0.0312 0.1535
Mycobacterium ulcerans acyl-CoA synthetase 0.0015 0.0001 0.0032
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0083 0.0202 0.0202
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0109 0.0528
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0704 0.2033 0.346
Mycobacterium tuberculosis Conserved hypothetical protein 0.0155 0.0414 0.9752
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.023 0.0637 0.3098
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0066 0.0323
Schistosoma mansoni cathepsin B (C01 family) 0.012 0.0312 0.0531
Brugia malayi Isocitrate dehydrogenase 0.0023 0.0025 0.0042
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0816 0.3963
Leishmania major cathepsin L-like protease 0.0392 0.1115 0.5484
Mycobacterium ulcerans lipase LipD 0.0025 0.0031 0.0757
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0044 0.0087 0.0148
Echinococcus multilocularis smad 0.0024 0.0028 0.0028
Leishmania major importin beta-1 subunit, putative 0.0035 0.006 0.0295
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.012 0.0312 0.1517
Loa Loa (eye worm) hypothetical protein 0.0083 0.0202 0.0206
Echinococcus multilocularis JmjC domain containing protein 4 0.0017 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0111 0.0284 0.029
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0039 0.0075 0.0127
Giardia lamblia Cathepsin B precursor 0.012 0.0312 0.1535
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0083 0.0202 0.0206
Onchocerca volvulus 0.0474 0.1355 0.6053
Giardia lamblia Cysteine protease 0.012 0.0312 0.1535
Schistosoma mansoni cpg binding protein 0.0059 0.0131 0.0223
Mycobacterium tuberculosis Probable lipase LipE 0.0025 0.0031 0.0738
Trichomonas vaginalis esterase, putative 0.0025 0.0031 0.0152
Treponema pallidum fructose-bisphosphate aldolase 0.0291 0.0816 1
Brugia malayi Cathepsin L-like precursor 0.011 0.0284 0.0483
Echinococcus granulosus peregrin 0.0024 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0774 0.2238 0.2285
Onchocerca volvulus 0.0022 0.0024 0.0103
Schistosoma mansoni phosphatidylserine receptor 0.0017 0.0007 0.0012
Schistosoma mansoni wnt inhibitor frzb2 0.007 0.0166 0.0282
Trichomonas vaginalis D-aminoacylase, putative 0.0025 0.0031 0.0152
Schistosoma mansoni nuclear hormone receptor 0.0083 0.0202 0.0344
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0042 0.0082 0.014
Schistosoma mansoni hypothetical protein 0.0111 0.0284 0.0484
Schistosoma mansoni smad1 5 8 and 0.0024 0.0028 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0392 0.1115 0.5417
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1115 0.5484
Leishmania major cathepsin L-like protease 0.0392 0.1115 0.5484
Toxoplasma gondii NAC domain-containing protein 0.0026 0.0036 0.0144
Brugia malayi Fz domain containing protein 0.007 0.0166 0.0282
Schistosoma mansoni hypothetical protein 0.0035 0.0062 0.0106
Trichomonas vaginalis chromobox protein, putative 0.0031 0.0049 0.0238
Loa Loa (eye worm) cathepsin B 0.0704 0.2033 0.2076
Echinococcus granulosus frizzled 4 0.0154 0.0411 0.0411
Trichomonas vaginalis CAMK family protein kinase 0.007 0.0163 0.0793
Echinococcus multilocularis cathepsin L cysteine protease 0.0392 0.1115 0.1115
Echinococcus granulosus Smad4 0.0024 0.0028 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0704 0.2033 0.9878
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0626 0.1803 0.1842
Schistosoma mansoni hypothetical protein 0.0111 0.0284 0.0484
Brugia malayi Papain family cysteine protease containing protein 0.023 0.0637 0.1085
Loa Loa (eye worm) hypothetical protein 0.0083 0.0202 0.0206
Echinococcus granulosus smad 0.0024 0.0028 0.0028
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0025 0.0031 0.0738
Schistosoma mansoni hypothetical protein 0.0111 0.0284 0.0484
Brugia malayi Papain family cysteine protease containing protein 0.023 0.0637 0.1085
Brugia malayi Steroid receptor seven-up type 2 0.0083 0.0202 0.0344
Entamoeba histolytica cysteine protease, putative 0.023 0.0637 0.5719
Schistosoma mansoni cpg binding protein 0.0064 0.0147 0.025
Onchocerca volvulus 0.0392 0.1115 0.4979
Schistosoma mansoni sex comb on midleg homolog 0.0086 0.0213 0.0362
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.012 0.0312 0.0531
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0083 0.0202 0.0344
Echinococcus granulosus nuclear receptor nhr 48 0.0039 0.0073 0.0073
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1115 0.5484
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0066 0.0596
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0111 0.0284 0.0284
Trypanosoma brucei importin beta-1 subunit, putative 0.0043 0.0084 0.0412
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0031 0.0051 0.0086
Echinococcus granulosus Niemann Pick C1 protein 0.032 0.09 0.09
Toxoplasma gondii hypothetical protein 0.0047 0.0098 0.0448
Brugia malayi Nuclear hormone receptor-like 1 0.0083 0.0202 0.0344
Brugia malayi TAR-binding protein 0.0241 0.0667 0.1136
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0022 0.0022 0.0107
Toxoplasma gondii cathepsin B 0.0704 0.2033 1
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0227 0.0627 0.1068
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0142 0.0377 1
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0023 0.0025 0.0161
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.023 0.0637 0.3136
Schistosoma mansoni hypothetical protein 0.0454 0.1297 0.2207
Schistosoma mansoni tar DNA-binding protein 0.0241 0.0667 0.1136
Loa Loa (eye worm) mbt repeat family protein 0.0086 0.0213 0.0217
Echinococcus multilocularis muscleblind protein 0.0305 0.0857 0.0857
Loa Loa (eye worm) frizzled/Smoothened family membrane region containing protein 0.0083 0.0203 0.0208
Loa Loa (eye worm) hypothetical protein 0.002 0.0018 0.0019
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0007 0.0007
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0011 0.0011
Brugia malayi Pre-SET motif family protein 0.0091 0.0226 0.0385
Trichomonas vaginalis penicillin-binding protein, putative 0.0025 0.0031 0.0152
Schistosoma mansoni Smad4 0.0024 0.0028 0.0048
Onchocerca volvulus 0.0392 0.1115 0.4979
Schistosoma mansoni jumonji domain containing protein 0.0017 0.0007 0.0012
Entamoeba histolytica cysteine protease, putative 0.012 0.0312 0.2799
Brugia malayi ecdysone receptor 0.0039 0.0073 0.0125
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0075
Echinococcus multilocularis SAM and MBT domain containing protein 0.0086 0.0213 0.0213
Plasmodium vivax importin-beta 2, putative 0.0043 0.0084 0.0692
Plasmodium vivax basic transcription factor 3b, putative 0.0026 0.0036 0.0263
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0282 0.0789 0.1344
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0075
Brugia malayi Glycosyl hydrolases family 31 protein 0.0165 0.0445 0.0758
Echinococcus granulosus lysosomal alpha glucosidase 0.0165 0.0445 0.0445
Schistosoma mansoni frizzled-like receptor 0.0154 0.0411 0.0699
Entamoeba histolytica cysteine protease, putative 0.023 0.0637 0.5719
Entamoeba histolytica cysteine protease, putative 0.023 0.0637 0.5719
Giardia lamblia Cathepsin L precursor 0.012 0.0312 0.1535
Brugia malayi STAT protein, DNA binding domain containing protein 0.0141 0.0373 0.0635
Brugia malayi ecdysteroid receptor 0.0083 0.0202 0.0344
Mycobacterium leprae conserved hypothetical protein 0.0025 0.0031 0.0799
Loa Loa (eye worm) hypothetical protein 0.0239 0.0663 0.0677
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0083 0.0202 0.0202
Echinococcus multilocularis neuropeptide s receptor 0.0607 0.1747 0.1747
Schistosoma mansoni hypothetical protein 0.0083 0.0203 0.0346
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0091 0.0226 0.1082
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0454 0.1297 0.1324
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0031 0.0051 0.0249
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0083 0.0202 0.0202
Plasmodium vivax SET domain protein, putative 0.0091 0.0226 0.1979
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0029 0.0043 0.0185
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0023 0.0025 0.0042
Leishmania major mitochondrial DNA polymerase beta 0.0294 0.0823 0.4051
Brugia malayi Muscleblind-like protein 0.0305 0.0857 0.1459
Mycobacterium tuberculosis Conserved protein 0.0025 0.0031 0.0738
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0075
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0392 0.1115 0.5417
Echinococcus multilocularis lamin 0.002 0.0018 0.0018
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0042 0.0082 0.0406
Loa Loa (eye worm) pigment dispersing factor receptor c 0.035 0.0989 0.101
Echinococcus granulosus histone lysine methyltransferase setb 0.0108 0.0277 0.0277
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.012 0.0312 0.1517
Echinococcus granulosus mitogen activated protein kinase 0.0039 0.0075 0.0075
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0039 0.0075 0.0367
Echinococcus multilocularis thyroid hormone receptor alpha 0.0083 0.0202 0.0202
Brugia malayi nuclear receptor NHR-67 0.0039 0.0073 0.0125
Entamoeba histolytica cysteine proteinase, putative 0.023 0.0637 0.5719
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0023 0.0025 0.0586
Leishmania major DNA polymerase eta, putative 0.0033 0.0055 0.027
Toxoplasma gondii aldehyde dehydrogenase 0.0059 0.0132 0.0618
Trypanosoma cruzi cysteine peptidase, putative 0.011 0.0284 0.0483
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0066 0.0113
Schistosoma mansoni frizzled 0.0154 0.0411 0.0699
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0031 0.0051 0.0393
Entamoeba histolytica papain family cysteine protease domain containing protein 0.012 0.0312 0.2799
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0031 0.0051 0.0086
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0098 0.0248 0.0248
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0816 0.3963
Brugia malayi Bromodomain containing protein 0.0079 0.0192 0.0327
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0004 0.0019
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0042 0.0082 0.014
Trichomonas vaginalis chaperonin, putative 0.0017 0.0007 0.0036
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0083 0.0202 0.0344
Giardia lamblia Cysteine protease 0.012 0.0312 0.1535
Plasmodium vivax unspecified product 0.012 0.0312 0.2753
Mycobacterium ulcerans hypothetical protein 0.0025 0.0031 0.0757
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0083 0.0202 0.0344
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0075
Echinococcus granulosus sterol regulatory element binding protein 0.0096 0.0241 0.0241
Schistosoma mansoni hypothetical protein 0.0021 0.0021 0.0036
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0012 0.0021
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0012 0.011
Loa Loa (eye worm) hypothetical protein 0.0083 0.0202 0.0206
Loa Loa (eye worm) nuclear receptor NHR-67 0.0039 0.0073 0.0075
Echinococcus granulosus intermediate filament protein 0.002 0.0018 0.0018
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0083 0.0202 0.0344
Brugia malayi jmjC domain containing protein 0.0017 0.0007 0.0012
Schistosoma mansoni jumonji/arid domain-containing protein 0.0067 0.0157 0.0267
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.012 0.0312 0.2753
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0039 0.0073 0.0073
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0083 0.0202 0.0202
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0083 0.0202 0.0202
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0066 0.0323
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0066 0.0323
Loa Loa (eye worm) jmjC domain-containing protein 0.0067 0.0157 0.016
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.0242 0.0242
Toxoplasma gondii HEAT repeat-containing protein 0.0043 0.0084 0.0378
Loa Loa (eye worm) hypothetical protein 0.0124 0.0325 0.0331
Echinococcus granulosus transcription factor btf3 0.0026 0.0036 0.0036
Entamoeba histolytica cysteine protease, putative 0.023 0.0637 0.5719
Loa Loa (eye worm) hypothetical protein 0.0305 0.0857 0.0875
Loa Loa (eye worm) intermediate filament protein 0.002 0.0018 0.0019
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0042 0.0082 0.0082
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.012 0.0312 0.1517
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0022 0.0107
Echinococcus granulosus neuropeptide s receptor 0.0607 0.1747 0.1747
Echinococcus granulosus PHD finger protein rhinoceros 0.0021 0.0021 0.0021
Schistosoma mansoni lamin 0.002 0.0018 0.0031
Brugia malayi beta-lactamase 0.0025 0.0031 0.0053
Echinococcus multilocularis cathepsin b 0.2008 0.5875 0.5875
Echinococcus multilocularis Smad4 0.0024 0.0028 0.0028
Loa Loa (eye worm) sfrp2 0.007 0.0166 0.0169
Brugia malayi cathepsin F-like cysteine proteinase 0.012 0.0312 0.0531
Onchocerca volvulus 0.0392 0.1115 0.4979
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0066 0.0066
Schistosoma mansoni lozenge 0.0059 0.0134 0.0227
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0108 0.0277 0.0472
Plasmodium vivax serine-repeat antigen (SERA) 0.012 0.0312 0.2753
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0039 0.0073 0.0073
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.035 0.0989 0.1683
Schistosoma mansoni hypothetical protein 0.0069 0.0161 0.0275
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0083 0.0202 0.0344
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0017 0.0007 0.0013
Trichomonas vaginalis CMGC family protein kinase 0.0039 0.0075 0.0363
Loa Loa (eye worm) hypothetical protein 0.0029 0.0043 0.0044
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0704 0.2033 0.346
Onchocerca volvulus 0.007 0.0166 0.0736
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0392 0.1115 0.5417
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0083 0.0202 0.0344
Echinococcus multilocularis Protein lozenge 0.0059 0.0134 0.0134
Brugia malayi MH1 domain containing protein 0.0024 0.0028 0.0048
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0158 0.0425 1
Loa Loa (eye worm) hypothetical protein 0.012 0.0312 0.0319
Brugia malayi MH2 domain containing protein 0.0024 0.0028 0.0048
Onchocerca volvulus Cathepsin L homolog 0.012 0.0312 0.139
Loa Loa (eye worm) hypothetical protein 0.007 0.0166 0.0169
Schistosoma mansoni bromodomain containing protein 0.0068 0.0157 0.0268
Onchocerca volvulus 0.0035 0.0062 0.0273
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0392 0.1115 0.5417
Echinococcus granulosus cpg binding protein 0.0064 0.0147 0.0147
Loa Loa (eye worm) hypothetical protein 0.012 0.0312 0.0319
Schistosoma mansoni protein phosphatase 2C 0.0017 0.0007 0.0012
Loa Loa (eye worm) hypothetical protein 0.0083 0.0203 0.0208
Trypanosoma brucei glucosidase, putative 0.0037 0.0066 0.0327
Schistosoma mansoni DNA polymerase eta 0.0033 0.0055 0.0094
Brugia malayi cathepsin B-like cysteine proteinase 0.2008 0.5875 1
Echinococcus granulosus lysine specific demethylase 6a 0.0017 0.0007 0.0007
Brugia malayi Smad1 0.0024 0.0028 0.0048
Schistosoma mansoni nuclear hormone receptor 0.0039 0.0073 0.0125
Toxoplasma gondii PHD-finger domain-containing protein 0.0021 0.0021 0.007
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0042 0.0082 0.014
Schistosoma mansoni frizzled-like receptor 0.0154 0.0411 0.0699
Echinococcus multilocularis isocitrate dehydrogenase 0.0023 0.0025 0.0025
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0083 0.0202 0.0206
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.023 0.0637 0.1085
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.008 0.0136
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0025 0.0031 0.0032
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0096 0.0242 0.0247
Onchocerca volvulus 0.0083 0.0202 0.0897
Brugia malayi beta-NAC-like protein 0.0026 0.0036 0.0062
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0039 0.0073 0.0073
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.023 0.0637 0.1085
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0039 0.0075 0.0127
Loa Loa (eye worm) hypothetical protein 0.0044 0.0087 0.0089
Echinococcus granulosus mitogen activated protein kinase 3 0.0039 0.0075 0.0075
Schistosoma mansoni hypothetical protein 0.0021 0.002 0.0034
Trypanosoma cruzi cysteine proteinase, putative 0.023 0.0637 0.1085
Brugia malayi nuclear receptor NHR-88 0.0083 0.0202 0.0344
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0392 0.1115 0.5417
Entamoeba histolytica acyl-CoA synthetase, putative 0.0015 0.0001 0.0012
Entamoeba histolytica cysteine proteinase, putative 0.023 0.0637 0.5719
Echinococcus granulosus Nuclear hormone receptor HR96 0.0039 0.0073 0.0073
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0226 0.0385
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0392 0.1115 0.5417
Brugia malayi hypothetical protein 0.0039 0.0073 0.0125
Giardia lamblia Cathepsin L-like protease 0.012 0.0312 0.1535
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0083 0.0202 0.0206
Trypanosoma cruzi transcription factor btf3, putative 0.0026 0.0036 0.0062
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0036 0.0176
Echinococcus granulosus frizzled 5 0.0154 0.0411 0.0411
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0023 0.0025 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0392 0.1115 0.5417
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0392 0.1115 0.5417
Loa Loa (eye worm) steroid hormone receptor 0.0083 0.0202 0.0206
Echinococcus granulosus phd:f box containing protein 0.0017 0.0007 0.0007
Entamoeba histolytica cysteine proteinase, putative 0.023 0.0637 0.5719
Giardia lamblia TCP-1 chaperonin subunit beta 0.0017 0.0007 0.0037
Echinococcus granulosus histone acetyltransferase MYST2 0.0098 0.0248 0.0248
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1115 0.5484
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0012 0.0012
Schistosoma mansoni smad1 5 8 and 0.0024 0.0028 0.0048
Plasmodium falciparum serine repeat antigen 9 0.012 0.0312 0.2753
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0025 0.0031 0.0053
Entamoeba histolytica acyl-CoA synthetase, putative 0.0015 0.0001 0.0012
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.012 0.0312 0.0531
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0012 0.0021
Entamoeba histolytica cysteine protease, putative 0.023 0.0637 0.5719
Giardia lamblia Cysteine protease 0.012 0.0312 0.1535
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0039 0.0073 0.0322
Entamoeba histolytica cysteine protease, putative 0.023 0.0637 0.5719
Trypanosoma cruzi ISWI complex protein 0.0016 0.0004 0.0007
Leishmania major cathepsin L-like protease 0.0392 0.1115 0.5484
Brugia malayi hypothetical protein 0.0044 0.0087 0.0148
Loa Loa (eye worm) hypothetical protein 0.0043 0.0084 0.0086
Trichomonas vaginalis chromobox protein, putative 0.0051 0.0109 0.0528
Brugia malayi Cathepsin L-like precursor 0.0282 0.0789 0.1344
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0066 0.0113
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.012 0.0312 0.0531
Entamoeba histolytica cysteine proteinase, putative 0.0392 0.1115 1
Entamoeba histolytica acyl-coA synthetase, putative 0.0015 0.0001 0.0012
Schistosoma mansoni microtubule-associated protein tau 0.0521 0.1494 0.2543
Trypanosoma brucei transcription factor BTF3, putative 0.0026 0.0036 0.0178
Brugia malayi nuclear hormone receptor 0.0083 0.0202 0.0344
Brugia malayi Intermediate filament tail domain containing protein 0.002 0.0018 0.0031
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0294 0.0823 0.1401
Trichomonas vaginalis conserved hypothetical protein 0.012 0.0312 0.1517
Plasmodium vivax serine-repeat antigen (SERA), putative 0.012 0.0312 0.2753
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0039 0.0075 0.0367
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2008 0.5875 1
Trypanosoma cruzi cruzipain precursor, putative 0.011 0.0284 0.0483
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0392 0.1115 0.5417
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0042 0.0082 0.0084
Schistosoma mansoni tar DNA-binding protein 0.0241 0.0667 0.1136
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0066 0.0113
Echinococcus granulosus FTZ F1 alpha 0.0083 0.0202 0.0202
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0083 0.0202 0.0206
Echinococcus granulosus muscleblind protein 0.0305 0.0857 0.0857
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0066 0.0327
Trichomonas vaginalis set domain proteins, putative 0.0713 0.2058 1
Echinococcus granulosus lamin dm0 0.002 0.0018 0.0018
Entamoeba histolytica cysteine proteinase, putative 0.0282 0.0789 0.7081
Entamoeba histolytica cysteine proteinase 1, putative 0.023 0.0637 0.5719
Brugia malayi CXXC zinc finger family protein 0.0059 0.0131 0.0223
Brugia malayi F/Y-rich N-terminus family protein 0.003 0.0047 0.008
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0294 0.0823 0.1401
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0083 0.0202 0.0344
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0012 0.006
Loa Loa (eye worm) STAT protein 0.0141 0.0373 0.0381
Brugia malayi Frizzled/Smoothened family membrane region containing protein 0.0154 0.0411 0.0699
Loa Loa (eye worm) hypothetical protein 0.0041 0.008 0.0082
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0021 0.0021 0.0036
Entamoeba histolytica hypothetical protein 0.012 0.0312 0.2799
Brugia malayi hypothetical protein 0.0039 0.0073 0.0125
Trypanosoma cruzi DNA polymerase eta, putative 0.0023 0.0026 0.0045
Loa Loa (eye worm) hypothetical protein 0.0044 0.0087 0.0089
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0012 0.0012
Echinococcus multilocularis cpg binding protein 0.0064 0.0147 0.0147
Schistosoma mansoni alpha-glucosidase 0.0142 0.0377 0.0643
Echinococcus multilocularis FTZ F1 alpha 0.0083 0.0202 0.0202
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0128 0.0335 0.057
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0059 0.0132 0.3116
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0015 0.0001 0.0032
Entamoeba histolytica cysteine protease, putative 0.023 0.0637 0.5719
Loa Loa (eye worm) hypothetical protein 0.0083 0.0202 0.0206
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.008 0.0394
Brugia malayi follicle stimulating hormone receptor 0.0465 0.1327 0.2259
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0392 0.1115 0.5417
Echinococcus multilocularis lysosomal alpha glucosidase 0.0165 0.0445 0.0445
Echinococcus multilocularis frizzled 0.0154 0.0411 0.0411
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0042 0.0082 0.014
Schistosoma mansoni tar DNA-binding protein 0.0241 0.0667 0.1136
Plasmodium falciparum serine repeat antigen 4 0.012 0.0312 0.2753
Trichomonas vaginalis conserved hypothetical protein 0.0096 0.0241 0.1172
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0022 0.0107
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0165 0.0445 0.0455
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0106 0.0271 0.0271
Entamoeba histolytica cysteine protease, putative 0.023 0.0637 0.5719
Entamoeba histolytica cysteine protease, putative 0.012 0.0312 0.2799
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.012 0.0312 0.1535
Brugia malayi Bromodomain containing protein 0.0024 0.0028 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.012 0.0312 0.1517
Loa Loa (eye worm) hypothetical protein 0.0046 0.0095 0.0097
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0025 0.0031 0.0738
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0291 0.0816 0.3963
Echinococcus granulosus Niemann Pick C1 protein 0.0224 0.0617 0.0617
Loa Loa (eye worm) hypothetical protein 0.2008 0.5875 0.6
Toxoplasma gondii cathepsin CPC1 0.012 0.0312 0.1506
Onchocerca volvulus Alhambra homolog 0.0021 0.0021 0.0089
Echinococcus granulosus TGF beta signal transducer SmadC 0.0024 0.0028 0.0028
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.002 0.0018 0.0019
Schistosoma mansoni hypothetical protein 0.0132 0.0348 0.0593
Schistosoma mansoni tar DNA-binding protein 0.0241 0.0667 0.1136
Loa Loa (eye worm) cysteine protease 0.0392 0.1115 0.1138
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0083 0.0202 0.0344
Brugia malayi Cathepsin L-like precursor 0.0392 0.1115 0.1897
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0031 0.0051 0.0249
Loa Loa (eye worm) hypothetical protein 0.007 0.0166 0.0169
Schistosoma mansoni retinoic acid receptor RXR 0.0083 0.0202 0.0344
Loa Loa (eye worm) hypothetical protein 0.0021 0.0021 0.0022
Loa Loa (eye worm) papain family cysteine protease containing protein 0.011 0.0284 0.029
Echinococcus granulosus jumonji domain containing 1A 0.0017 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0083 0.0203 0.0208
Schistosoma mansoni smad 0.0024 0.0028 0.0048
Trichomonas vaginalis CAMK family protein kinase 0.007 0.0163 0.0793
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0083 0.0202 0.0202
Mycobacterium ulcerans hypothetical protein 0.0155 0.0414 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0075
Echinococcus granulosus jumonji domain containing protein 0.003 0.0046 0.0046
Echinococcus granulosus lysine specific demethylase 5A 0.0067 0.0157 0.0157
Onchocerca volvulus Serine\/threonine kinase homolog 0.007 0.0163 0.0724
Brugia malayi Cathepsin L-like precursor 0.0392 0.1115 0.1897
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0044 0.0087 0.0089
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0001 0.0002
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0111 0.0284 0.0284
Loa Loa (eye worm) hypothetical protein 0.0305 0.0857 0.0875
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0001 0.0002
Onchocerca volvulus 0.0086 0.0213 0.0946
Brugia malayi jmjC domain containing protein 0.0106 0.0271 0.0461
Schistosoma mansoni hypothetical protein 0.0083 0.0203 0.0346
Echinococcus multilocularis expressed conserved protein 0.021 0.0577 0.0577
Giardia lamblia Cathepsin B precursor 0.0704 0.2033 1
Echinococcus granulosus cathepsin b 0.2008 0.5875 0.5875
Schistosoma mansoni ap endonuclease 0.0018 0.0012 0.0021
Mycobacterium ulcerans aldehyde dehydrogenase 0.0059 0.0132 0.3195
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0023 0.0025 0.0122
Entamoeba histolytica T-complex protein 1 beta subunit, putative 0.0017 0.0007 0.0067
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0031 0.0051 0.0393
Schistosoma mansoni lamin 0.002 0.0018 0.0031
Schistosoma mansoni chromobox protein 0.0051 0.0109 0.0185
Schistosoma mansoni cpg binding protein 0.0064 0.0147 0.025
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0083 0.0202 0.0202
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0012 0.006
Loa Loa (eye worm) DR-78 0.0039 0.0073 0.0075
Loa Loa (eye worm) hypothetical protein 0.0083 0.0202 0.0206
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0017 0.0007 0.0013
Echinococcus granulosus snurportin 1 0.0454 0.1297 0.1297
Echinococcus granulosus JmjC domain containing protein 4 0.0017 0.0007 0.0007
Toxoplasma gondii exonuclease III APE 0.0018 0.0012 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0083 0.0202 0.0344
Echinococcus multilocularis cysteine protease 0.0392 0.1115 0.1115
Onchocerca volvulus 0.0025 0.0031 0.0134
Echinococcus multilocularis cathepsin L 0.012 0.0312 0.0312
Echinococcus granulosus GPCR family 2 0.0111 0.0284 0.0284
Giardia lamblia Cathepsin B precursor 0.012 0.0312 0.1535
Onchocerca volvulus 0.0392 0.1115 0.4979
Entamoeba histolytica transcription factor BTF3, putative 0.0026 0.0036 0.0324
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0015 0.0001 0.0032
Trypanosoma cruzi DNA polymerase eta, putative 0.0033 0.0055 0.0094
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0392 0.1115 0.5417
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0142 0.0377 0.9109
Trichomonas vaginalis CMGC family protein kinase 0.0039 0.0075 0.0363
Brugia malayi Nuclear hormone receptor E75 0.0039 0.0073 0.0125
Trichomonas vaginalis CAMK family protein kinase 0.0035 0.006 0.0293
Entamoeba histolytica hypothetical protein 0.0026 0.0036 0.0324
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0066 0.0066
Echinococcus multilocularis frizzled 4 0.0154 0.0411 0.0411
Giardia lamblia Cathepsin L precursor 0.012 0.0312 0.1535
Schistosoma mansoni aldehyde dehydrogenase 0.0059 0.0132 0.0225
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0282 0.0789 0.3836
Loa Loa (eye worm) hypothetical protein 0.0083 0.0202 0.0206
Giardia lamblia Hypothetical protein 0.012 0.0312 0.1535
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0042 0.0082 0.0082
Schistosoma mansoni secreted frizzled-related protein 0.007 0.0166 0.0282
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0108 0.0277 0.0472
Brugia malayi hypothetical protein 0.0173 0.0468 0.0796
Brugia malayi RNA binding protein 0.0241 0.0667 0.1136
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0021 0.0128
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0242 0.0412
Echinococcus multilocularis musashi 0.002 0.0018 0.0018
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0066 0.0068
Echinococcus multilocularis histone acetyltransferase MYST2 0.0098 0.0248 0.0248
Leishmania major basic transcription factor 3a, putative 0.0026 0.0036 0.0178
Loa Loa (eye worm) hypothetical protein 0.0282 0.0789 0.0806
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0075 0.0127
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0392 0.1115 1
Onchocerca volvulus 0.0392 0.1115 0.4979
Brugia malayi Papain family cysteine protease containing protein 0.012 0.0312 0.0531
Leishmania major GTP-binding protein, putative 0.0031 0.0051 0.0249
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.008 0.0136
Onchocerca volvulus 0.0039 0.0073 0.0322
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0059 0.0132 0.0132
Echinococcus multilocularis lamin dm0 0.002 0.0018 0.0018
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0392 0.1115 0.1138
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0111 0.0284 0.0484
Echinococcus multilocularis frizzled 10 0.0154 0.0411 0.0411
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0007 0.0012
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0142 0.0377 0.8883
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0017 0.0007 0.0037
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0291 0.0816 0.7316
Loa Loa (eye worm) hypothetical protein 0.0108 0.0277 0.0283
Trichomonas vaginalis CAMK family protein kinase 0.007 0.0163 0.0793
Onchocerca volvulus 0.0096 0.024 0.1067
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0075
Trypanosoma brucei polo-like protein kinase 0.007 0.0163 0.0803
Echinococcus multilocularis frizzled 5 0.0154 0.0411 0.0411
Loa Loa (eye worm) hypothetical protein 0.0017 0.0007 0.0007
Schistosoma mansoni serine/threonine protein kinase 0.007 0.0163 0.0278
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0007 0.0007
Entamoeba histolytica hypothetical protein 0.0132 0.0348 0.3126
Plasmodium falciparum basic transcription factor 3b, putative 0.0026 0.0036 0.0263
Brugia malayi fibroinase precursor 0.012 0.0312 0.0531
Schistosoma mansoni chromobox protein 0.0051 0.0109 0.0185
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0241 0.0667 0.0682
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.012 0.0312 0.1517
Echinococcus granulosus microtubule associated protein 2 0.0521 0.1494 0.1494
Echinococcus multilocularis secreted frizzled protein 0.007 0.0166 0.0166
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0392 0.1115 0.5417
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0392 0.1115 0.5417
Plasmodium vivax serine-repeat antigen (SERA) 0.012 0.0312 0.2753
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.023 0.0637 0.3136
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0039 0.0075 0.0076
Entamoeba histolytica cysteine protease, putative 0.0392 0.1115 1
Loa Loa (eye worm) frizzled/Smoothened family membrane region containing protein 0.0154 0.0411 0.042
Leishmania major cysteine peptidase A (CPA) 0.0392 0.1115 0.5484
Schistosoma mansoni hypothetical protein 0.0239 0.0663 0.1128
Onchocerca volvulus 0.002 0.0018 0.0076
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0392 0.1115 1
Schistosoma mansoni hypothetical protein 0.0093 0.0231 0.0393
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0039 0.0075 0.0334
Schistosoma mansoni nuclear receptor nhr-48 0.0039 0.0073 0.0125
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0022 0.0022 0.0107
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0083 0.0202 0.0206
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1115 0.5484
Loa Loa (eye worm) hypothetical protein 0.0039 0.0073 0.0075
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.012 0.0312 0.0531
Plasmodium falciparum serine repeat antigen 6 0.012 0.0312 0.2753
Leishmania major cathepsin L-like protease 0.0392 0.1115 0.5484
Loa Loa (eye worm) nuclear hormone receptor 0.0039 0.0073 0.0075
Loa Loa (eye worm) hypothetical protein 0.0474 0.1355 0.1384
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.023 0.0637 0.3098
Brugia malayi PHD-finger family protein 0.0021 0.0021 0.0036
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0015 0.0001 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0083 0.0202 0.0344
Brugia malayi Frizzled/Smoothened family membrane region containing protein 0.0083 0.0203 0.0346
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0392 0.1115 0.5417
Trypanosoma cruzi cysteine peptidase, putative 0.0392 0.1115 0.1897
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0066 0.0293
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0392 0.1115 0.5484
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0023 0.0025 0.0042
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0083 0.0202 0.0344
Brugia malayi Papain family cysteine protease containing protein 0.012 0.0312 0.0531
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0099 0.0251 0.0427
Schistosoma mansoni hypothetical protein 0.0093 0.0231 0.0393
Brugia malayi jmjC domain containing protein 0.0017 0.0007 0.0012
Loa Loa (eye worm) hypothetical protein 0.0033 0.0055 0.0056
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0392 0.1115 0.5417
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0131 0.0134
Schistosoma mansoni zinc finger protein 0.0023 0.0027 0.0045
Echinococcus granulosus GTP binding nuclear protein Ran 0.0031 0.0051 0.0051
Echinococcus multilocularis cysteine protease 0.0392 0.1115 0.1115
Onchocerca volvulus Protein ultraspiracle homolog 0.0083 0.0202 0.0897
Trypanosoma brucei ISWI complex protein 0.0016 0.0004 0.002
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0083 0.0202 0.0202
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.007 0.0163 0.0163
Loa Loa (eye worm) heterochromatin protein 1 0.0051 0.0109 0.0111
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0044 0.0087 0.0087
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0021 0.0022 0.0022
Onchocerca volvulus 0.0392 0.1115 0.4979
Schistosoma mansoni cellular tumor antigen P53 0.0038 0.0071 0.0121

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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