Detailed information for compound 619719

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 379.247 | Formula: C16H12BrFN2OS
  • H donors: 0 H acceptors: 1 LogP: 4.74 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCn1c(=NC(=O)c2ccccc2F)sc2c1ccc(c2)Br
  • InChi: 1S/C16H12BrFN2OS/c1-2-20-13-8-7-10(17)9-14(13)22-16(20)19-15(21)11-5-3-4-6-12(11)18/h3-9H,2H2,1H3/b19-16+
  • InChiKey: BTXYTCORMFEVBG-KNTRCKAVSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.0008 0.0007 0.0007
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0119 0.0274 0.1666
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.0008 0.0007 0.0007
Trichomonas vaginalis glucosylceramidase, putative 0.057 0.1351 1
Treponema pallidum NADH oxidase 0.0016 0.0028 1
Echinococcus multilocularis carbonyl reductase 1 0.0008 0.0007 0.0007
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0007 0.0025
Loa Loa (eye worm) hypothetical protein 0.0099 0.0226 0.082
Mycobacterium ulcerans carboxylesterase, LipT 0.0196 0.0457 1
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0029 0.0058 0.1146
Plasmodium falciparum histone acetyltransferase GCN5 0.0044 0.0093 0.5436
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0007 0.0025
Toxoplasma gondii ATPase, AAA family protein 0.001 0.0012 0.0217
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0058 0.0212
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0007 0.0025
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0028 0.0882
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0007 0.0025
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0029 0.0058 0.2191
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.001 0.0012 0.0113
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0007 0.0025
Loa Loa (eye worm) hypothetical protein 0.0074 0.0166 0.0602
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0007 0.0025
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0029 0.0058 0.2191
Leishmania major acetyl-CoA synthetase, putative 0.0029 0.0058 0.2191
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0008 0.0007 0.0007
Onchocerca volvulus Sepiapterin reductase homolog 0.0008 0.0007 0.0078
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0028 0.0882
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0013 0.0013
Trichomonas vaginalis steroid dehydrogenase, putative 0.0008 0.0007 0.001
Brugia malayi Bromodomain containing protein 0.0006 0.0002 0.0009
Loa Loa (eye worm) inositol-1 0.0036 0.0075 0.0271
Echinococcus granulosus BC026374 protein S09 family 0.0196 0.0457 0.1656
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0029 0.0058 0.2191
Trichomonas vaginalis glucosylceramidase, putative 0.0374 0.0883 0.6518
Loa Loa (eye worm) hypothetical protein 0.0006 0.0002 0.0009
Schistosoma mansoni bromodomain containing protein 0.0006 0.0002 0.0009
Echinococcus granulosus replication factor c subunit 1 0.001 0.0012 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0013 0.0046
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0005 0.0001 0.0005
Echinococcus multilocularis tumor protein p63 0.0702 0.1669 0.1669
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0029 0.0058 0.0322
Loa Loa (eye worm) hypothetical protein 0.0196 0.0457 0.1656
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0058 0.0212
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.001 0.0012 0.0047
Trypanosoma cruzi trypanothione reductase, putative 0.0016 0.0028 0.0882
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0029 0.0058 0.2191
Loa Loa (eye worm) patched family protein 0.0025 0.0048 0.0176
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0028 0.0882
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0029 0.0058 0.0212
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Echinococcus granulosus steroid dehydrogenase 0.0008 0.0007 0.0025
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Echinococcus multilocularis carboxylesterase 5A 0.1158 0.2759 0.2759
Brugia malayi Patched family protein 0.0025 0.0048 0.0176
Echinococcus granulosus para nitrobenzyl esterase 0.0196 0.0457 0.1656
Mycobacterium ulcerans hypothetical protein 0.0099 0.0226 0.4875
Giardia lamblia NADH oxidase lateral transfer candidate 0.0016 0.0028 0.2397
Schistosoma mansoni transcription factor LCR-F1 0.011 0.0253 0.0916
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0016 0.0028 0.0882
Echinococcus multilocularis para nitrobenzyl esterase 0.0196 0.0457 0.0457
Echinococcus multilocularis polycomb protein SCMH1 0.0047 0.0102 0.0102
Loa Loa (eye worm) hypothetical protein 0.0008 0.0007 0.0025
Trichomonas vaginalis glucosylceramidase, putative 0.0374 0.0883 0.6518
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0013 0.0046
Mycobacterium tuberculosis Probable hydrolase 0.0106 0.0242 0.1469
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0046
Mycobacterium tuberculosis Probable oxidoreductase 0.0119 0.0274 0.1666
Echinococcus multilocularis sterol regulatory element binding protein 0.0177 0.0412 0.0412
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.001 0.0012 0.0217
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0099 0.0226 0.137
Onchocerca volvulus 0.001 0.0012 0.0135
Mycobacterium ulcerans acyl-CoA synthetase 0.0099 0.0226 0.4875
Schistosoma mansoni hypothetical protein 0.0171 0.0397 0.1438
Echinococcus granulosus retinol dehydrogenase 11 0.0008 0.0007 0.0025
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Loa Loa (eye worm) oxidoreductase 0.0008 0.0007 0.0025
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0102 0.037
Brugia malayi Dehydrogenases, short chain protein 30 0.0008 0.0007 0.0025
Onchocerca volvulus 0.0196 0.0457 0.5173
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0046
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0099 0.0226 0.8223
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.0008 0.0007 0.0025
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0013 0.0046
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0095 0.0346
Leishmania major trypanothione reductase 0.0047 0.0101 0.4003
Schistosoma mansoni cellular tumor antigen P53 0.0103 0.0235 0.085
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0008 0.0007 0.0078
Echinococcus multilocularis zinc finger protein 0.0006 0.0002 0.0002
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0013 0.0046
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0029 0.0058 0.2191
Echinococcus multilocularis neuroligin 0.0196 0.0457 0.0457
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0007 0.0025
Echinococcus multilocularis retinol dehydrogenase 11 0.0008 0.0007 0.0007
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0029 0.0058 0.0322
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0058 0.1146
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0007 0.0026
Brugia malayi steroid hormone receptor 0.001 0.0013 0.0046
Loa Loa (eye worm) hypothetical protein 0.1158 0.2759 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0058 0.1146
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.001 0.0012 0.0751
Brugia malayi Niemann-Pick C1 protein precursor 0.0412 0.0975 0.3534
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0046
Onchocerca volvulus 0.0008 0.0007 0.0078
Onchocerca volvulus 0.0106 0.0242 0.2742
Echinococcus multilocularis microtubule associated protein 2 0.0773 0.1839 0.1839
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0047
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0016 0.0028 0.0461
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0007 0.0025
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0013 0.0046
Onchocerca volvulus 0.0025 0.0048 0.0549
Echinococcus granulosus sterol regulatory element binding protein 0.0177 0.0412 0.1493
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0013 0.0046
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0061 0.0134 0.2826
Mycobacterium leprae conserved hypothetical protein 0.0106 0.0242 0.8822
Brugia malayi Carboxylesterase family protein 0.0196 0.0457 0.1656
Echinococcus granulosus carboxylesterase 5A 0.1158 0.2759 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0013 0.0046
Echinococcus granulosus tumor protein p63 0.0702 0.1669 0.6049
Mycobacterium ulcerans acyl-CoA synthetase 0.0099 0.0226 0.4875
Brugia malayi CXXC zinc finger family protein 0.0031 0.0063 0.0229
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Brugia malayi oxidoreductase 0.0008 0.0007 0.0025
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Toxoplasma gondii ABC1 family protein 0.0106 0.0242 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0013 0.0046
Echinococcus granulosus histone acetyltransferase KAT2B 0.0048 0.0103 0.0373
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.0008 0.0007 0.0025
Brugia malayi topoisomerase 0.001 0.0012 0.0043
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0101 0.0101
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0058 0.0212
Schistosoma mansoni topbp1 0.001 0.0012 0.0043
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0028 0.0882
Loa Loa (eye worm) hypothetical protein 0.0034 0.0071 0.0257
Toxoplasma gondii histone lysine methyltransferase SET1 0.0063 0.0139 0.5636
Echinococcus granulosus carbonyl reductase 1 0.0008 0.0007 0.0025
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0007 0.0025
Onchocerca volvulus 0.0008 0.0007 0.0078
Echinococcus multilocularis oxidoreductase 0.0008 0.0007 0.0007
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0029 0.0058 0.1146
Loa Loa (eye worm) hypothetical protein 0.0008 0.0007 0.0025
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0075 0.0701
Brugia malayi nuclear receptor RXR 0.0005 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.0043
Leishmania major acetyl-CoA synthetase, putative 0.0029 0.0058 0.2191
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0047
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0196 0.0457 0.1656
Echinococcus granulosus histone acetyltransferase MYST2 0.0054 0.0118 0.0427
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0013 0.0046
Onchocerca volvulus 0.0008 0.0007 0.0078
Loa Loa (eye worm) acetyltransferase 0.0162 0.0377 0.1368
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0034 0.0071 0.0257
Loa Loa (eye worm) hypothetical protein 0.0029 0.0058 0.0212
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0007 0.0025
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0075 0.2885
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0029 0.0058 0.0058
Schistosoma mansoni cpg binding protein 0.0031 0.0063 0.0229
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0016 0.0028 0.0028
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0419 0.099 0.3589
Onchocerca volvulus 0.001 0.0013 0.0144
Loa Loa (eye worm) hypothetical protein 0.0074 0.0166 0.0602
Echinococcus multilocularis Niemann Pick C1 protein 0.0412 0.0975 0.0975
Trichomonas vaginalis penicillin-binding protein, putative 0.0106 0.0242 0.1757
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0007 0.0025
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0075 0.0514
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0007 0.0025
Brugia malayi protein C24B5.3 0.0025 0.0048 0.0176
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0013 0.0046
Brugia malayi Patched family protein 0.0025 0.0048 0.0176
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0028 0.0882
Brugia malayi AMP-binding enzyme family protein 0.0099 0.0226 0.082
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0106 0.0242 0.0878
Schistosoma mansoni carbonyl reductase 0.0008 0.0007 0.0025
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0162 0.0377 0.0377
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0029 0.0058 0.1933
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0061 0.0134 0.0794
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Loa Loa (eye worm) oxidoreductase 0.0008 0.0007 0.0025
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0013 0.0046
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0005 0.0001 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0013 0.0046
Brugia malayi AMP-binding enzyme family protein 0.0099 0.0226 0.082
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0196 0.0457 0.1656
Plasmodium vivax replication factor C subunit 1, putative 0.001 0.0012 0.0217
Brugia malayi Immunoglobulin I-set domain containing protein 0.0034 0.0071 0.0257
Schistosoma mansoni neuroligin 3 (S09 family) 0.0196 0.0457 0.1656
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0196 0.0457 0.1656
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0016 0.0028 0.0882
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0016 0.0028 0.0882
Entamoeba histolytica acetyltransferase, GNAT family 0.0044 0.0093 0.0894
Brugia malayi Patched family protein 0.0025 0.0048 0.0176
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0029 0.0058 0.1146
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 1 homolog 0.0008 0.0007 0.0078
Loa Loa (eye worm) carboxylesterase 0.0196 0.0457 0.1656
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0013 0.0046
Schistosoma mansoni hypothetical protein 0.0034 0.0071 0.0257
Brugia malayi beta-lactamase family protein 0.0106 0.0242 0.0878
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0013 0.0046
Brugia malayi dehydrogenases, short chain protein 9 0.0008 0.0007 0.0025
Onchocerca volvulus 0.0029 0.0058 0.0661
Echinococcus multilocularis nibrin 0.001 0.0012 0.0012
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0099 0.0226 0.4875
Trichomonas vaginalis D-aminoacylase, putative 0.0106 0.0242 0.1757
Schistosoma mansoni nuclear hormone receptor 0.001 0.0013 0.0046
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0016 0.0028 0.1303
Trichomonas vaginalis spcc417.12 protein, putative 0.0196 0.0457 0.3352
Schistosoma mansoni cpg binding protein 0.0033 0.0067 0.0245
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.0008 0.0007 0.0025
Trichomonas vaginalis glucosylceramidase, putative 0.057 0.1351 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0046
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0007 0.0025
Echinococcus multilocularis retinol dehydrogenase 13 0.0008 0.0007 0.0007
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0099 0.0226 0.4875
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0013 0.0013
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0162 0.0377 0.1368
Echinococcus granulosus expressed conserved protein 0.0387 0.0915 0.3317
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0007 0.0025
Trypanosoma brucei trypanothione reductase 0.0047 0.0101 0.4003
Brugia malayi Patched family protein 0.0025 0.0048 0.0176
Mycobacterium ulcerans acyl-CoA synthetase 0.0099 0.0226 0.4875
Brugia malayi Patched family protein 0.0025 0.0048 0.0176
Schistosoma mansoni acetyl-CoA synthetase 0.0029 0.0058 0.0212
Loa Loa (eye worm) hypothetical protein 0.0196 0.0457 0.1656
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Schistosoma mansoni microtubule-associated protein tau 0.0773 0.1839 0.6666
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0107 0.0245 0.1487
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0047
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0013 0.0046
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0005 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0099 0.0226 0.082
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0101 0.4003
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Onchocerca volvulus 0.0196 0.0457 0.5173
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0029 0.0058 0.2191
Plasmodium falciparum thioredoxin reductase 0.0047 0.0101 0.5912
Echinococcus granulosus nibrin 0.001 0.0012 0.0043
Schistosoma mansoni chromosome transmission fidelity factor 0.001 0.0012 0.0043
Brugia malayi dehydrogenases, short chain protein 2 0.0008 0.0007 0.0025
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Echinococcus multilocularis acetylcholinesterase 0.1158 0.2759 0.2759
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0046
Entamoeba histolytica acyl-coA synthetase, putative 0.0099 0.0226 0.2266
Loa Loa (eye worm) beta-lactamase 0.0106 0.0242 0.0878
Trichomonas vaginalis glucosylceramidase, putative 0.0374 0.0883 0.6518
Echinococcus multilocularis SAM and MBT domain containing protein 0.0047 0.0102 0.0102
Trypanosoma cruzi hypothetical protein, conserved 0.0106 0.0242 1
Schistosoma mansoni coup transcription factor 0.001 0.0013 0.0046
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0095 0.0095
Brugia malayi hypothetical protein 0.0025 0.0048 0.0176
Schistosoma mansoni acetylcholinesterase 0.0196 0.0457 0.1656
Loa Loa (eye worm) hypothetical protein 0.0008 0.0007 0.0025
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0074 0.0166 1
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0029 0.0058 0.1146
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0016 0.0028 0.0461
Mycobacterium ulcerans esterase/lipase LipP 0.0106 0.0242 0.523
Loa Loa (eye worm) hypothetical protein 0.0196 0.0457 0.1656
Leishmania major 4-coumarate:coa ligase-like protein 0.0099 0.0226 0.9322
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0007 0.0025
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0029 0.0058 0.0322
Brugia malayi Pax transcription activation domain interacting protein 0.001 0.0012 0.0043
Loa Loa (eye worm) hypothetical protein 0.0196 0.0457 0.1656
Loa Loa (eye worm) hypothetical protein 0.0047 0.0102 0.037
Loa Loa (eye worm) hypothetical protein 0.0196 0.0457 0.1656
Schistosoma mansoni ankyrin 23/unc44 0.0034 0.0071 0.0257
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0016 0.0028 0.0882
Onchocerca volvulus 0.0029 0.0058 0.0661
Onchocerca volvulus Netrin receptor homolog 0.0034 0.0071 0.0802
Entamoeba histolytica hypothetical protein 0.011 0.0253 0.2539
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0013 0.0046
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0013 0.0013
Mycobacterium ulcerans acetyl-CoA synthetase 0.0029 0.0058 0.1146
Loa Loa (eye worm) hypothetical protein 0.0034 0.0071 0.0258
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0028 0.0882
Onchocerca volvulus Protein ultraspiracle homolog 0.001 0.0013 0.0144
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0048 0.0103 0.4085
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0007 0.0025
Loa Loa (eye worm) oxidoreductase 0.0008 0.0007 0.0025
Brugia malayi hypothetical protein 0.0196 0.0457 0.1656
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0048 0.0103 0.0724
Loa Loa (eye worm) hypothetical protein 0.0005 0.0001 0.0005
Echinococcus granulosus WW domain containing oxidoreductase 0.0008 0.0007 0.0025
Brugia malayi mbt repeat family protein 0.0047 0.0102 0.037
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0196 0.0457 0.3352
Mycobacterium tuberculosis Carboxylesterase LipT 0.0196 0.0457 0.281
Toxoplasma gondii propionate-CoA ligase 0.0029 0.0058 0.2191
Trichomonas vaginalis glucosylceramidase, putative 0.0394 0.0931 0.6876
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.0008 0.0007 0.0025
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0029 0.0058 0.1146
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0007 0.0025
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0099 0.0226 0.4875
Echinococcus multilocularis BC026374 protein (S09 family) 0.0196 0.0457 0.0457
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0075 0.2885
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.0147 0.0532
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0013 0.0046
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0028 0.3058
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0101 0.0588
Trichomonas vaginalis D-aminoacylase, putative 0.0106 0.0242 0.1757
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0058 0.1146
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0029 0.0058 0.1146
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0013 0.0046
Loa Loa (eye worm) hypothetical protein 0.0196 0.0457 0.1656
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0049 0.0261
Echinococcus multilocularis beta LACTamase domain containing family member 0.0106 0.0242 0.0242
Plasmodium falciparum lipid/sterol:H+ symporter 0.0025 0.0048 0.2614
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0007 0.0025
Mycobacterium tuberculosis Probable lipase LipD 0.0106 0.0242 0.1469
Loa Loa (eye worm) hypothetical protein 0.1158 0.2759 1
Echinococcus granulosus Ankyrin 0.0034 0.0071 0.0258
Brugia malayi Patched family protein 0.0025 0.0048 0.0176
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.0043
Onchocerca volvulus 0.0025 0.0048 0.0549
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0099 0.0226 0.4875
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0013 0.0046
Schistosoma mansoni hypothetical protein 0.011 0.0253 0.0916
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.0008 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0196 0.0457 0.1656
Schistosoma mansoni gliotactin 0.0196 0.0457 0.1656
Schistosoma mansoni BC026374 protein (S09 family) 0.0196 0.0457 0.1656
Brugia malayi glutathione reductase 0.0047 0.0101 0.0366
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0006 0.0002 0.0002
Schistosoma mansoni carbonyl reductase 0.0008 0.0007 0.0025
Brugia malayi Carboxylesterase family protein 0.0196 0.0457 0.1656
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0047
Schistosoma mansoni retinal dehydrogenase 0.0008 0.0007 0.0025
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Onchocerca volvulus 0.0008 0.0007 0.0078
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Mycobacterium ulcerans hypothetical protein 0.0106 0.0242 0.523
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0013 0.0046
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.0008 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0106 0.0242 0.0878
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.057 0.1351 0.4899
Brugia malayi Patched family protein 0.0025 0.0048 0.0176
Plasmodium vivax patched family protein, putative 0.0025 0.0048 0.1769
Onchocerca volvulus 0.0196 0.0457 0.5173
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0106 0.0242 0.523
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0007 0.0025
Echinococcus multilocularis acetylcholinesterase 0.1158 0.2759 0.2759
Echinococcus multilocularis carbonyl reductase 1 0.0008 0.0007 0.0007
Brugia malayi hypothetical protein 0.0008 0.0007 0.0025
Loa Loa (eye worm) patched family protein 0.0025 0.0048 0.0176
Schistosoma mansoni zinc finger protein 0.0006 0.0002 0.0009
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0007 0.0025
Echinococcus granulosus microtubule associated protein 2 0.0773 0.1839 0.6666
Loa Loa (eye worm) hypothetical protein 0.0103 0.0235 0.085
Schistosoma mansoni hypothetical protein 0.0102 0.0233 0.0843
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0007 0.0025
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0007 0.0025
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0196 0.0457 0.0457
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0008 0.0007 0.0007
Brugia malayi Carboxylesterase family protein 0.1158 0.2759 1
Trichomonas vaginalis glucosylceramidase, putative 0.0374 0.0883 0.6518
Trichomonas vaginalis D-aminoacylase, putative 0.0106 0.0242 0.1757
Loa Loa (eye worm) hypothetical protein 0.0008 0.0007 0.0025
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0075 0.0271
Onchocerca volvulus 0.0008 0.0007 0.0078
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0095 0.0346
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0107 0.0245 0.1487
Loa Loa (eye worm) MBCTL1 0.0054 0.0118 0.0427
Onchocerca volvulus 0.0008 0.0007 0.0078
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0095 0.0346
Leishmania major 4-coumarate:coa ligase-like protein 0.0099 0.0226 0.9322
Brugia malayi acetyltransferase, GNAT family protein 0.0162 0.0377 0.1368
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.1158 0.2759 1
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0061 0.0134 0.5403
Echinococcus granulosus death domain containing protein 0.0034 0.0071 0.0257
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0013 0.0046
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0058 0.1146
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0012 0.0217
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0034 0.0071 0.0258
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0007 0.0025
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0061 0.0134 0.0486
Brugia malayi CHE-14 protein 0.0177 0.0412 0.1493
Loa Loa (eye worm) histone methyltransferase 0.001 0.0012 0.0043
Loa Loa (eye worm) hypothetical protein 0.0008 0.0007 0.0025
Echinococcus granulosus histone acetyltransferase KAT2B 0.0158 0.0366 0.1328
Brugia malayi hypothetical protein 0.0025 0.0048 0.0176
Loa Loa (eye worm) hypothetical protein 0.0008 0.0007 0.0025
Loa Loa (eye worm) patched family protein 0.0025 0.0048 0.0176
Echinococcus granulosus survival motor neuron protein 1 0.05 0.1184 0.4294
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0095 0.0346
Schistosoma mansoni thyroid hormone receptor 0.001 0.0013 0.0046
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.001 0.0012 0.0047
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0007 0.0025
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0061 0.0134 0.0486
Brugia malayi hypothetical protein 0.0005 0.0001 0.0005
Schistosoma mansoni cpg binding protein 0.0033 0.0067 0.0245
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0177 0.0412 0.1493
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0013 0.0046
Onchocerca volvulus 0.0025 0.0048 0.0549
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0107 0.0245 0.1487
Giardia lamblia Replication factor C, subunit 1 0.001 0.0012 0.0589
Onchocerca volvulus 0.0029 0.0058 0.0661
Brugia malayi Carboxylesterase family protein 0.0196 0.0457 0.1656
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0058 0.0322
Plasmodium vivax glutathione reductase, putative 0.0047 0.0101 0.4003
Plasmodium falciparum acyl-CoA synthetase 0.0074 0.0166 1
Trypanosoma cruzi hypothetical protein, conserved 0.0106 0.0242 1
Trichomonas vaginalis glucosylceramidase, putative 0.057 0.1351 1
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0029 0.0058 0.3237
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0048 0.0103 0.4085
Toxoplasma gondii patched family protein 0.0025 0.0048 0.1769
Brugia malayi Patched related family protein 4 0.0025 0.0048 0.0176
Brugia malayi DKFZp564C0469 protein 0.001 0.0012 0.0043
Schistosoma mansoni hypothetical protein 0.0171 0.0397 0.1438
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0013 0.0046
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0007 0.0025
Leishmania major hypothetical protein, conserved 0.0106 0.0242 1
Toxoplasma gondii patched family protein 0.0025 0.0048 0.1769
Echinococcus multilocularis dnaJ subfamily B 0.0444 0.105 0.105
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0013 0.0046
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0095 0.0346
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0013 0.0046
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Brugia malayi Patched family protein 0.0025 0.0048 0.0176
Trichomonas vaginalis conserved hypothetical protein 0.0177 0.0412 0.3019
Onchocerca volvulus 0.0025 0.0048 0.0549
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0107 0.0245 0.1487
Echinococcus granulosus acetylcholinesterase 0.1158 0.2759 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0013 0.0046
Echinococcus multilocularis transient receptor potential cation channel 0.0008 0.0007 0.0007
Brugia malayi Patched family protein 0.0025 0.0048 0.0176
Loa Loa (eye worm) hypothetical protein 0.0412 0.0975 0.3534
Echinococcus multilocularis netrin receptor unc 5 0.0034 0.0071 0.0071
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0013 0.0046
Giardia lamblia Histone acetyltransferase GCN5 0.0044 0.0093 1
Loa Loa (eye worm) hypothetical protein 0.0008 0.0007 0.0025
Trypanosoma cruzi hypothetical protein, conserved 0.001 0.0012 0.0217
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0029 0.0058 0.0322
Echinococcus multilocularis cpg binding protein 0.0033 0.0067 0.0067
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.007 0.0156 0.0934
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0016 0.0028 0.01
Trichomonas vaginalis glucosylceramidase, putative 0.057 0.1351 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0034 0.0071 0.0257
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0106 0.0242 0.0878
Trichomonas vaginalis bromodomain-containing protein, putative 0.0048 0.0103 0.0724
Plasmodium falciparum glutathione reductase 0.0047 0.0101 0.5912
Loa Loa (eye worm) oxidoreductase 0.0008 0.0007 0.0025
Loa Loa (eye worm) hypothetical protein 0.0099 0.0226 0.082
Brugia malayi AMP-binding enzyme family protein 0.0029 0.0058 0.0212
Brugia malayi AMP-binding enzyme family protein 0.0099 0.0226 0.082
Loa Loa (eye worm) hypothetical protein 0.0106 0.0242 0.0878
Brugia malayi Patched related family protein 10 0.0025 0.0048 0.0176
Echinococcus granulosus retinol dehydrogenase 11 0.0008 0.0007 0.0025
Brugia malayi beta-lactamase 0.0106 0.0242 0.0878
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.0043
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0006 0.0002 0.0009
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0061 0.0134 0.2826
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0007 0.0025
Brugia malayi hypothetical protein 0.0008 0.0007 0.0025
Schistosoma mansoni inositol monophosphatase 0.0036 0.0075 0.0271
Brugia malayi hypothetical protein 0.0025 0.0048 0.0176
Loa Loa (eye worm) oxidoreductase 0.0029 0.0058 0.0212
Loa Loa (eye worm) hypothetical protein 0.0217 0.0507 0.1838
Plasmodium vivax acyl-CoA synthetase, putative 0.0074 0.0166 0.677
Brugia malayi Nuclear hormone receptor-like 1 0.0005 0.0001 0.0005
Brugia malayi Dehydrogenases, short chain protein 2 0.0008 0.0007 0.0025
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Echinococcus multilocularis carbonyl reductase 1 0.0008 0.0007 0.0007
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0016 0.0028 0.1016
Plasmodium falciparum glutathione reductase 0.0016 0.0028 0.1303
Brugia malayi Patched family protein 0.0025 0.0048 0.0176
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0007 0.0025
Loa Loa (eye worm) patched family protein 0.0025 0.0048 0.0176
Schistosoma mansoni hypothetical protein 0.0288 0.0678 0.2456
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0029 0.0058 0.1933
Loa Loa (eye worm) oxidoreductase 0.0008 0.0007 0.0025
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0013 0.0046
Echinococcus multilocularis conserved hypothetical protein 0.0008 0.0007 0.0007
Mycobacterium tuberculosis Probable dehydrogenase 0.0107 0.0245 0.1487
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0013 0.0046
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0187 0.0435 0.1578
Brugia malayi Protein kinase domain containing protein 0.0034 0.0071 0.0257
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Schistosoma mansoni myelin transcription factor 1 myt1 0.0054 0.0118 0.0427
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0029 0.0058 0.2191
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0011 0.0041
Onchocerca volvulus 0.0031 0.0063 0.0716
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0016 0.0028 0.0882
Loa Loa (eye worm) acetylcholinesterase 1 0.1158 0.2759 1
Entamoeba histolytica hypothetical protein 0.001 0.0012 0.0053
Onchocerca volvulus 0.0196 0.0457 0.5173
Brugia malayi Uncoordinated protein 44 0.0034 0.0071 0.0257
Loa Loa (eye worm) hypothetical protein 0.0106 0.0242 0.0878
Echinococcus granulosus beta LACTamase domain containing family member 0.0106 0.0242 0.0878
Plasmodium falciparum thioredoxin reductase 0.0016 0.0028 0.1303
Brugia malayi Patched family protein 0.0025 0.0048 0.0176
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0075 0.2885
Schistosoma mansoni short-chain dehydrogenase/reductase 0.0008 0.0007 0.0025
Onchocerca volvulus 0.0025 0.0048 0.0549
Mycobacterium tuberculosis Probable lipase LipE 0.0106 0.0242 0.1469
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0075 0.0514
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.0008 0.0007 0.0025
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0007 0.0025
Mycobacterium ulcerans lipase LipD 0.0106 0.0242 0.523
Loa Loa (eye worm) carboxylesterase 0.0196 0.0457 0.1656
Onchocerca volvulus 0.0196 0.0457 0.5173
Loa Loa (eye worm) hypothetical protein 0.0029 0.0058 0.0212
Loa Loa (eye worm) hypothetical protein 0.0074 0.0166 0.0602
Trichomonas vaginalis glucosylceramidase, putative 0.0394 0.0931 0.6876
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.0008 0.0007 0.0025
Loa Loa (eye worm) hypothetical protein 0.0054 0.0118 0.0427
Loa Loa (eye worm) hypothetical protein 0.0074 0.0166 0.0602
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0101 0.4003
Onchocerca volvulus 0.0047 0.0102 0.1155
Echinococcus multilocularis expressed conserved protein 0.0387 0.0915 0.0915
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0013 0.0046
Brugia malayi hypothetical protein 0.0005 0.0001 0.0005
Brugia malayi ecdysteroid receptor 0.001 0.0013 0.0046
Echinococcus granulosus carbonyl reductase 1 0.0008 0.0007 0.0025
Echinococcus granulosus polycomb protein SCMH1 0.0047 0.0102 0.037
Toxoplasma gondii NADPH-glutathione reductase 0.0016 0.0028 0.0882
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.001 0.0012 0.0217
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0013 0.0013
Loa Loa (eye worm) mbt repeat family protein 0.0047 0.0102 0.037
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.0043
Onchocerca volvulus 0.0008 0.0007 0.0078
Echinococcus granulosus hypothetical protein 0.0008 0.0007 0.0025
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0029 0.0058 0.0212
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0336 0.0792 0.0792
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0095 0.0095
Loa Loa (eye worm) dehydrogenase 0.0008 0.0007 0.0025
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0013 0.0046
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0106 0.0242 0.0878
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0412 0.0975 1
Onchocerca volvulus 0.0099 0.0226 0.2562
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0013 0.0046
Loa Loa (eye worm) carboxylesterase 0.1158 0.2759 1
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0016 0.0028 0.3058
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.001 0.0012 0.0191
Schistosoma mansoni inositol monophosphatase 0.0036 0.0075 0.0271
Leishmania major 4-coumarate:coa ligase-like protein 0.0099 0.0226 0.9322
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0029 0.0058 0.0212
Toxoplasma gondii thioredoxin reductase 0.0047 0.0101 0.4003
Echinococcus multilocularis protein dispatched 1 0.0202 0.0472 0.0472
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0007 0.001
Brugia malayi Patched family protein 0.0025 0.0048 0.0176
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0013 0.0013
Echinococcus multilocularis steroid dehydrogenase 0.0008 0.0007 0.0007
Brugia malayi hypothetical protein 0.011 0.0253 0.0916
Echinococcus granulosus cpg binding protein 0.0033 0.0067 0.0245
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Mycobacterium tuberculosis Conserved protein 0.0106 0.0242 0.1469
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0101 0.0366
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0102 0.0233 0.0843
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0013 0.0046
Onchocerca volvulus 0.0103 0.0235 0.2657
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0007 0.0025
Brugia malayi PHD-finger family protein 0.0006 0.0002 0.0009
Loa Loa (eye worm) hypothetical protein 0.0005 0.0001 0.0005
Brugia malayi nuclear receptor NHR-88 0.001 0.0013 0.0046
Loa Loa (eye worm) hypothetical protein 0.05 0.1184 0.4294
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0007 0.0025
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Entamoeba histolytica acyl-CoA synthetase, putative 0.0099 0.0226 0.2266
Trichomonas vaginalis glucosylceramidase, putative 0.057 0.1351 1
Echinococcus granulosus Protein patched homolog 1 0.0177 0.0412 0.1493
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0046
Trichomonas vaginalis antibiotic synthetase, putative 0.0029 0.0058 0.0393
Loa Loa (eye worm) hypothetical protein 0.0106 0.0242 0.0878
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.001 0.0012 0.0047
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0029 0.0058 0.2191
Trichomonas vaginalis glucosylceramidase, putative 0.0374 0.0883 0.6518
Echinococcus multilocularis carbonyl reductase 1 0.0008 0.0007 0.0007
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0017 0.0063
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0099 0.0226 0.137
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.001 0.0012 0.0043
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0074 0.0166 0.354
Trichomonas vaginalis glucosylceramidase, putative 0.0374 0.0883 0.6518
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0013 0.0013
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0029 0.0058 0.0533
Schistosoma mansoni hypothetical protein 0.0171 0.0397 0.1438
Loa Loa (eye worm) oxidoreductase 0.0008 0.0007 0.0025
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0119 0.0274 0.1666
Loa Loa (eye worm) hypothetical protein 0.0005 0.0001 0.0005
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.007 0.0156 0.0934
Loa Loa (eye worm) hypothetical protein 0.0008 0.0007 0.0025
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0007 0.0025
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0075 1
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0007 0.001
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0007 0.001
Brugia malayi nuclear hormone receptor 0.001 0.0013 0.0046
Mycobacterium leprae Probable lipase LipE 0.0106 0.0242 0.8822
Trypanosoma cruzi FHA domain containing protein, putative 0.001 0.0012 0.0217
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.001 0.0013 0.0144
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0007 0.001
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0005 0.0001 0.0001
Echinococcus granulosus SAM and MBT domain containing protein 0.0047 0.0102 0.037
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0017 0.0063
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.001 0.0012 0.0217
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0075 0.2885
Loa Loa (eye worm) oxidoreductase 0.0008 0.0007 0.0025
Brugia malayi Nuclear hormone receptor-like 1 0.0005 0.0001 0.0005
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.007 0.0156 0.0934
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0029 0.0058 0.1933
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0029 0.0058 0.2191
Echinococcus granulosus FTZ F1 alpha 0.001 0.0013 0.0046
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Mycobacterium tuberculosis Probable reductase 0.0107 0.0245 0.1487
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0107 0.0245 0.8928
Schistosoma mansoni topbp1 0.001 0.0012 0.0043
Brugia malayi Inositol-1 0.0036 0.0075 0.0271
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.007 0.0156 0.0934
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0187 0.0435 0.0435
Schistosoma mansoni DNA ligase IV 0.001 0.0012 0.0043
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0095 0.0346
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0007 0.001
Echinococcus multilocularis Ankyrin 0.0034 0.0071 0.0071
Onchocerca volvulus 0.0008 0.0007 0.0078
Echinococcus multilocularis histone acetyltransferase MYST2 0.0054 0.0118 0.0118
Echinococcus granulosus carbonyl reductase 1 0.0008 0.0007 0.0025
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0058 0.1146
Brugia malayi Patched protein homolog 1 0.0025 0.0048 0.0176
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0196 0.0457 0.1656
Onchocerca volvulus Protein patched homolog 0.0025 0.0048 0.0549
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0007 0.0025
Echinococcus granulosus acetylcholinesterase 0.1158 0.2759 1
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0106 0.0242 0.1469
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0016 0.0028 0.0882
Trichomonas vaginalis mercuric reductase, putative 0.0016 0.0028 0.0164
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0029 0.0058 0.1146
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0102 0.037
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0008 0.0007 0.0026
Onchocerca volvulus Glucosylceramidase homolog 0.0374 0.0883 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0013 0.0046
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.0008 0.0007 0.001
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0029 0.0058 0.0322
Onchocerca volvulus Bile acid receptor homolog 0.001 0.0013 0.0144
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0032 0.0066 0.2207
Onchocerca volvulus 0.0008 0.0007 0.0078
Mycobacterium ulcerans beta-lactamase 0.0106 0.0242 0.523
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0061 0.0134 0.0134
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0058 0.0322
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0007 0.0025
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0106 0.0242 0.1469
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0013 0.0046
Loa Loa (eye worm) oxidoreductase 0.0008 0.0007 0.0025
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0013 0.0046
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0012 0.0047
Brugia malayi Retinol dehydrogenase 12 0.0008 0.0007 0.0025
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.0008 0.0007 0.0007
Brugia malayi hypothetical protein 0.001 0.0012 0.0043
Brugia malayi beta-lactamase family protein 0.0106 0.0242 0.0878
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0058 0.0322
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0016 0.0028 0.0882
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0016 0.0028 0.1303
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0016 0.0028 0.0882
Brugia malayi Patched family protein 0.0025 0.0048 0.0176
Brugia malayi hypothetical protein 0.0025 0.0048 0.0176
Echinococcus granulosus nuclear factor of activated T cells 5 0.0336 0.0792 0.2869
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0046
Brugia malayi Patched family protein 0.0025 0.0048 0.0176
Echinococcus granulosus Niemann Pick C1 protein 0.0589 0.1398 0.5068
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0029 0.0058 0.0212
Trichomonas vaginalis glutathione reductase, putative 0.0016 0.0028 0.0164
Echinococcus granulosus netrin receptor unc 5 0.0034 0.0071 0.0257
Echinococcus granulosus Niemann Pick C1 protein 0.0412 0.0975 0.3534
Plasmodium vivax hypothetical protein, conserved 0.0106 0.0242 1
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0054 0.0118 0.0427
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0029 0.0058 0.0212
Echinococcus granulosus dnaJ subfamily B 0.0444 0.105 0.3808
Onchocerca volvulus 0.0025 0.0048 0.0549
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0028 0.0882
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0013 0.0046
Echinococcus multilocularis protein patched 0.0177 0.0412 0.0412
Brugia malayi Death domain containing protein 0.0034 0.0071 0.0257
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0054 0.0118 0.0427
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.0008 0.0007 0.0025
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Loa Loa (eye worm) hypothetical protein 0.0005 0.0001 0.0005
Brugia malayi Patched related family protein 12 0.0025 0.0048 0.0176
Mycobacterium tuberculosis Conserved protein 0.0106 0.0242 0.1469
Loa Loa (eye worm) hypothetical protein 0.0106 0.0242 0.0878
Onchocerca volvulus 0.0008 0.0007 0.0078
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0016 0.0028 0.0461
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.0043
Trichomonas vaginalis replication factor C large subunit, putative 0.001 0.0012 0.0047
Mycobacterium tuberculosis Conserved protein 0.0106 0.0242 0.1469
Plasmodium vivax acetyl-CoA synthetase, putative 0.0029 0.0058 0.2191
Toxoplasma gondii patched family protein 0.0025 0.0048 0.1769
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.0008 0.0007 0.0025
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0048 0.0103 0.4085
Schistosoma mansoni bromodomain containing protein 0.0006 0.0002 0.0009
Onchocerca volvulus 0.0106 0.0242 0.2742
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Echinococcus granulosus hypothetical protein 0.0008 0.0007 0.0025
Brugia malayi protein C24B5.3 0.0025 0.0048 0.0176
Echinococcus multilocularis survival motor neuron protein 1 0.05 0.1184 0.1184
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0007 0.0025
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0058 0.0322
Brugia malayi mbt repeat family protein 0.0047 0.0102 0.037
Onchocerca volvulus 0.0008 0.0007 0.0078
Trichomonas vaginalis glucosylceramidase, putative 0.0374 0.0883 0.6518
Toxoplasma gondii hypothetical protein 0.0025 0.0048 0.1769
Echinococcus multilocularis steroid dehydrogenase 0.0008 0.0007 0.0007
Echinococcus granulosus carbonyl reductase 1 0.0008 0.0007 0.0025
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0013 0.0046
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0016 0.0028 0.0882
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0016 0.0028 0.0882
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0013 0.0046
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0007 0.001
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0013 0.0046
Brugia malayi Carboxylesterase family protein 0.1158 0.2759 1
Trichomonas vaginalis antibiotic synthetase, putative 0.0029 0.0058 0.0393
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0016 0.0028 0.013
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0106 0.0242 0.1469
Trichomonas vaginalis esterase, putative 0.0106 0.0242 0.1757
Onchocerca volvulus 0.0106 0.0242 0.2742
Onchocerca volvulus 0.0008 0.0007 0.0078
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0058 0.1146
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0007 0.0025
Brugia malayi Carboxylesterase family protein 0.0196 0.0457 0.1656
Mycobacterium tuberculosis Probable esterase LipL 0.0106 0.0242 0.1469
Entamoeba histolytica hypothetical protein 0.011 0.0253 0.2539
Entamoeba histolytica hypothetical protein 0.011 0.0253 0.2539
Brugia malayi hypothetical protein 0.05 0.1184 0.4294
Schistosoma mansoni hypothetical protein 0.0444 0.105 0.3808
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0061 0.0134 0.0486
Loa Loa (eye worm) hypothetical protein 0.0177 0.0412 0.1493
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0034 0.0071 0.0071
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0196 0.0457 0.281
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0063 0.0229
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0047 0.0102 0.037
Brugia malayi Thioredoxin reductase 0.0047 0.0101 0.0366
Schistosoma mansoni carbonyl reductase 0.0008 0.0007 0.0025
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.057 0.1351 0.4899
Onchocerca volvulus 0.0037 0.0077 0.0867
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0066 0.0368
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0119 0.0274 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0013 0.0046
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.001 0.0012 0.0053
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.011 0.0253 0.0253
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0196 0.0457 0.281
Schistosoma mansoni hypothetical protein 0.0171 0.0397 0.1438
Schistosoma mansoni netrin receptor unc5 0.0034 0.0071 0.0257
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0007 0.0025
Plasmodium falciparum replication factor C subunit 1, putative 0.001 0.0012 0.032
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0047 0.0102 0.1155
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0101 0.0366
Loa Loa (eye worm) hypothetical protein 0.0106 0.0242 0.0878
Loa Loa (eye worm) hypothetical protein 0.0008 0.0007 0.0025
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0007 0.0025
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Loa Loa (eye worm) oxidoreductase 0.0008 0.0007 0.0025
Loa Loa (eye worm) hypothetical protein 0.0074 0.0166 0.0602
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0058 0.1146
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0007 0.0025
Onchocerca volvulus 0.0102 0.0233 0.2634
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0013 0.0013
Schistosoma mansoni thyroid hormone receptor 0.001 0.0013 0.0046
Trichomonas vaginalis glucosylceramidase, putative 0.057 0.1351 1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0075 0.0514
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0012 0.0012
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0075 0.2885
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0029 0.0058 0.0322
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0106 0.0242 0.0878
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0074 0.0166 0.0995
Loa Loa (eye worm) hypothetical protein 0.0006 0.0002 0.0009
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0099 0.0226 0.8223
Loa Loa (eye worm) hypothetical protein 0.0008 0.0007 0.0025
Schistosoma mansoni patched 1 0.0177 0.0412 0.1493
Loa Loa (eye worm) patched family protein 0.0025 0.0048 0.0176
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.011 0.0253 0.0916
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0005 0.0001 0.0005
Brugia malayi Myosin head containing protein 0.0025 0.0048 0.0176
Loa Loa (eye worm) hypothetical protein 0.0005 0.0001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0054 0.0118 0.0118
Brugia malayi hypothetical protein 0.001 0.0012 0.0043
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0007 0.0025
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0007 0.0025
Mycobacterium ulcerans acyl-CoA synthetase 0.0029 0.0058 0.1146
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0677 0.1608 1
Loa Loa (eye worm) dehydrogenase 0.0008 0.0007 0.0025
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.001 0.0012 0.0047
Toxoplasma gondii patched family protein 0.0025 0.0048 0.1769
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.001 0.0013 0.0046
Onchocerca volvulus Dehydrogenase\/reductase SDR family member 13 homolog 0.0008 0.0007 0.0078
Entamoeba histolytica hypothetical protein 0.011 0.0253 0.2539
Loa Loa (eye worm) hypothetical protein 0.001 0.0012 0.0043
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0029 0.0058 0.0322
Brugia malayi Patched family protein 0.0025 0.0048 0.0176
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0029 0.0058 0.1146
Echinococcus multilocularis replication factor c subunit 1 0.001 0.0012 0.0012
Schistosoma mansoni survival motor neuron protein 0.0102 0.0233 0.0843
Echinococcus multilocularis Niemann Pick C1 protein 0.0589 0.1398 0.1398
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0012 0.0043
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0007 0.0025
Echinococcus granulosus oxidoreductase 0.0008 0.0007 0.0025
Entamoeba histolytica acyl-CoA synthetase, putative 0.0099 0.0226 0.2266
Schistosoma mansoni steroid dehydrogenase 0.0008 0.0007 0.0025
Loa Loa (eye worm) glutathione reductase 0.0047 0.0101 0.0366
Echinococcus granulosus mixed lineage leukemia protein mll 0.0008 0.0007 0.0026
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0053 0.0116 0.042
Echinococcus granulosus zinc finger protein 0.0006 0.0002 0.0009
Onchocerca volvulus 0.0025 0.0048 0.0549
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.0008 0.0007 0.0007
Onchocerca volvulus Protein patched homolog 0.0025 0.0048 0.0549
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0075 0.0075
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0016 0.0028 0.01
Trypanosoma brucei hypothetical protein, conserved 0.0106 0.0242 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0028 0.0882
Trichomonas vaginalis short-chain dehydrogenase, putative 0.0008 0.0007 0.001
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0016 0.0028 0.0882
Echinococcus granulosus neuroligin 0.0196 0.0457 0.1656
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0095 0.0346
Echinococcus multilocularis retinol dehydrogenase 11 0.0008 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0008 0.0007 0.0025
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0075 0.1509
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0016 0.0028 0.01
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0176
Trichomonas vaginalis penicillin-binding protein, putative 0.0106 0.0242 0.1757
Schistosoma mansoni short chain dehydrogenase 0.0008 0.0007 0.0025

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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