Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | hypothetical protein, conserved | 0.0056 | 0.0547 | 0.0491 |
Schistosoma mansoni | prokaryotic DNA topoisomerase | 0.0049 | 0.0382 | 0.0382 |
Schistosoma mansoni | glutaminase | 0.0272 | 0.529 | 0.529 |
Plasmodium vivax | DNA gyrase subunit A, putative | 0.0089 | 0.1256 | 0.1256 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0127 | 0.2094 | 0.4538 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0115 | 0.0115 |
Trypanosoma cruzi | DNA topoisomerase III, putative | 0.0049 | 0.0382 | 0.0303 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0337 | 0.6724 | 0.6724 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0107 | 0.0107 |
Leishmania major | DNA topoisomerase III, putative | 0.0049 | 0.0382 | 0.0303 |
Brugia malayi | Probable ClpP-like protease | 0.0077 | 0.1006 | 0.1006 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0449 | 0.0449 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 0.0449 | 0.0449 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0449 | 0.0449 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0127 | 0.2094 | 0.4538 |
Toxoplasma gondii | ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein | 0.016 | 0.2824 | 0.2824 |
Chlamydia trachomatis | DNA gyrase subunit B | 0.016 | 0.2824 | 0.5167 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0038 | 0.0148 | 0.0148 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.0115 | 0.0115 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0056 | 0.0547 | 0.0547 |
Loa Loa (eye worm) | glutathione reductase | 0.005 | 0.0405 | 0.0405 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0049 | 0.0378 | 0.0378 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0056 | 0.0547 | 0.0547 |
Echinococcus granulosus | DNA topoisomerase 3 beta 1 | 0.0049 | 0.0382 | 0.0382 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0138 | 0.0138 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0049 | 0.0378 | 0.0378 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0235 | 0.4477 | 1 |
Brugia malayi | glutathione reductase | 0.005 | 0.0405 | 0.0405 |
Schistosoma mansoni | hypothetical protein | 0.0296 | 0.5824 | 0.5824 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0052 | 0.0449 | 0.0449 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0077 | 0.1006 | 0.1006 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0055 | 0.0526 | 0.0526 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0037 | 0.0115 | 0.0128 |
Plasmodium vivax | DNA topoisomerase 3, putative | 0.0049 | 0.0382 | 0.0382 |
Leishmania major | mitochondrial DNA topoisomerase II | 0.0382 | 0.7715 | 0.8628 |
Brugia malayi | DNA topoisomerase II, alpha isozyme | 0.0486 | 1 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0055 | 0.0524 | 0.0524 |
Brugia malayi | hypothetical protein | 0.0056 | 0.0547 | 0.0547 |
Trypanosoma brucei | DNA topoisomerase III, putative | 0.0049 | 0.0382 | 0.0428 |
Brugia malayi | glutaminase DH11.1 | 0.0272 | 0.529 | 0.529 |
Trypanosoma cruzi | mitochondrial DNA topoisomerase II, putative | 0.0382 | 0.7715 | 0.8628 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.0115 | 0.0115 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0056 | 0.0547 | 0.0547 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 0.0449 | 0.0449 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.0115 | 0.0115 |
Brugia malayi | mbt repeat family protein | 0.0049 | 0.0378 | 0.0378 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.1006 | 0.2557 |
Loa Loa (eye worm) | RNA binding protein | 0.0207 | 0.3863 | 0.3863 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0056 | 0.0547 | 0.0491 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0052 | 0.0449 | 0.0449 |
Brugia malayi | DNA topoisomerase III | 0.0049 | 0.0382 | 0.0382 |
Loa Loa (eye worm) | thioredoxin reductase | 0.005 | 0.0405 | 0.0405 |
Trypanosoma brucei | DNA topoisomerase II beta, putative | 0.0437 | 0.8923 | 1 |
Trichomonas vaginalis | prokaryotic DNA topoisomerase, putative | 0.0049 | 0.0382 | 0.027 |
Schistosoma mansoni | tar DNA-binding protein | 0.0207 | 0.3863 | 0.3863 |
Schistosoma mansoni | tar DNA-binding protein | 0.0207 | 0.3863 | 0.3863 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.0115 | 0.0115 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0051 | 0.042 | 0.1543 |
Toxoplasma gondii | DNA topoisomerase family protein | 0.0049 | 0.0382 | 0.0382 |
Loa Loa (eye worm) | TOPoisomerase family member | 0.0486 | 1 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0115 | 0.0115 |
Chlamydia trachomatis | DNA gyrase subunit A | 0.0089 | 0.1256 | 0.1849 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0114 | 0.1814 | 0.3897 |
Trypanosoma brucei | DNA topoisomerase IA, putative | 0.0049 | 0.0382 | 0.0428 |
Schistosoma mansoni | hypothetical protein | 0.0337 | 0.6724 | 0.6724 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.0115 | 0.0115 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.005 | 0.0405 | 0.0666 |
Onchocerca volvulus | Putative DNA topoisomerase 2, mitochondrial | 0.0352 | 0.706 | 1 |
Brugia malayi | Probable DNA topoisomerase II | 0.0486 | 1 | 1 |
Echinococcus multilocularis | snurportin 1 | 0.0337 | 0.6724 | 0.6724 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0114 | 0.1814 | 0.3897 |
Trypanosoma brucei | DNA topoisomerase III, putative | 0.0049 | 0.0382 | 0.0428 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1006 | 0.1006 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0378 | 0.0378 |
Trypanosoma cruzi | DNA topoisomerase III, putative | 0.0049 | 0.0382 | 0.0303 |
Mycobacterium leprae | Probable DNA topoisomerase I TopA (omega-protein) (relaxing enzyme) (untwisting enzyme) (swivelase) (type I DNA topoisomerase) ( | 0.0049 | 0.0382 | 0.1349 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0049 | 0.0378 | 0.0378 |
Toxoplasma gondii | thioredoxin reductase | 0.005 | 0.0405 | 0.0405 |
Trichomonas vaginalis | glutaminase, putative | 0.0272 | 0.529 | 0.5236 |
Wolbachia endosymbiont of Brugia malayi | DNA gyrase subunit A | 0.0089 | 0.1256 | 0.3578 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0056 | 0.0547 | 0.0613 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.1006 | 0.1321 |
Onchocerca volvulus | 0.0049 | 0.0382 | 0.0385 | |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.159 | 0.159 |
Treponema pallidum | DNA gyrase, subunit B (gyrB) | 0.016 | 0.2824 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.159 | 0.159 |
Schistosoma mansoni | hypothetical protein | 0.0173 | 0.3115 | 0.3115 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0526 | 0.0526 |
Loa Loa (eye worm) | MBCTL1 | 0.0055 | 0.0526 | 0.0526 |
Trypanosoma brucei | trypanothione reductase | 0.005 | 0.0405 | 0.0454 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0055 | 0.0524 | 0.0524 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0055 | 0.0526 | 0.0526 |
Loa Loa (eye worm) | hypothetical protein | 0.0326 | 0.6481 | 0.6481 |
Echinococcus granulosus | DNA topoisomerase 3 alpha | 0.0049 | 0.0382 | 0.0382 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0547 | 0.0547 |
Brugia malayi | beta-lactamase | 0.0037 | 0.0115 | 0.0115 |
Giardia lamblia | DNA topoisomerase II | 0.0464 | 0.9528 | 1 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0055 | 0.0526 | 0.0526 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0207 | 0.3863 | 0.3863 |
Loa Loa (eye worm) | glutaminase | 0.0272 | 0.529 | 0.529 |
Loa Loa (eye worm) | DNA topoisomerase III | 0.0049 | 0.0382 | 0.0382 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.005 | 0.0405 | 0.033 |
Loa Loa (eye worm) | glutaminase 2 | 0.0272 | 0.529 | 0.529 |
Trypanosoma cruzi | mitochondrial DNA topoisomerase II, putative | 0.0382 | 0.7715 | 0.8628 |
Entamoeba histolytica | DNA topoisomerase II, putative | 0.0486 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0115 | 0.0115 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.159 | 0.159 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0192 | 0.3531 | 0.3531 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.1006 | 0.1723 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0077 | 0.1006 | 0.1006 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0055 | 0.0526 | 0.0526 |
Echinococcus granulosus | DNA topoisomerase 2 alpha | 0.0486 | 1 | 1 |
Trypanosoma cruzi | DNA topoisomerase III, putative | 0.0049 | 0.0382 | 0.0303 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0127 | 0.2094 | 1 |
Onchocerca volvulus | 0.0049 | 0.0378 | 0.0379 | |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.005 | 0.0405 | 0.0405 |
Leishmania major | DNA topoisomerase III, putative | 0.0049 | 0.0382 | 0.0303 |
Plasmodium falciparum | DNA gyrase subunit B | 0.016 | 0.2824 | 0.2824 |
Loa Loa (eye worm) | hypothetical protein | 0.0215 | 0.4033 | 0.4033 |
Brugia malayi | mbt repeat family protein | 0.0049 | 0.0378 | 0.0378 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0049 | 0.0378 | 0.0378 |
Mycobacterium ulcerans | DNA topoisomerase I | 0.0049 | 0.0382 | 0.0516 |
Trypanosoma brucei | DNA topoisomerase II alpha, putative | 0.0437 | 0.8923 | 1 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0049 | 0.0378 | 0.0378 |
Echinococcus multilocularis | DNA topoisomerase 3 beta 1 | 0.0049 | 0.0382 | 0.0382 |
Plasmodium falciparum | DNA gyrase subunit A | 0.0089 | 0.1256 | 0.1256 |
Brugia malayi | RNA binding protein | 0.0207 | 0.3863 | 0.3863 |
Schistosoma mansoni | DNA topoisomerase II | 0.0486 | 1 | 1 |
Plasmodium falciparum | DNA topoisomerase 2 | 0.0486 | 1 | 1 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.0115 | 0.0115 |
Mycobacterium ulcerans | DNA gyrase subunit B | 0.016 | 0.2824 | 0.5235 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0207 | 0.3863 | 0.3863 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0115 | 0.0115 |
Mycobacterium tuberculosis | Probable reductase | 0.0114 | 0.1814 | 0.3897 |
Treponema pallidum | DNA gyrase, subunit A (gyrA) | 0.0089 | 0.1256 | 0.3578 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0077 | 0.1006 | 0.1006 |
Mycobacterium tuberculosis | DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) | 0.016 | 0.2824 | 0.6212 |
Schistosoma mansoni | tar DNA-binding protein | 0.0207 | 0.3863 | 0.3863 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0115 | 0.0115 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0077 | 0.1006 | 0.4504 |
Toxoplasma gondii | DNA topoisomerase domain-containing protein | 0.0049 | 0.0382 | 0.0382 |
Brugia malayi | GRF zinc finger family protein | 0.0049 | 0.0382 | 0.0382 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0051 | 0.042 | 0.042 |
Loa Loa (eye worm) | hypothetical protein | 0.0326 | 0.6481 | 0.6481 |
Plasmodium falciparum | thioredoxin reductase | 0.005 | 0.0405 | 0.0405 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0055 | 0.0526 | 0.0526 |
Leishmania major | trypanothione reductase | 0.005 | 0.0405 | 0.033 |
Plasmodium vivax | DNA topoisomerase II, putative | 0.0486 | 1 | 1 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.1006 | 0.1321 |
Schistosoma mansoni | tar DNA-binding protein | 0.0207 | 0.3863 | 0.3863 |
Entamoeba histolytica | DNA topoisomerase III, putative | 0.0049 | 0.0382 | 0.0237 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0056 | 0.0547 | 0.0491 |
Echinococcus multilocularis | rho GTPase activating protein 20 | 0.0049 | 0.0382 | 0.0382 |
Brugia malayi | DNA topoisomerase III beta-1 | 0.0049 | 0.0382 | 0.0382 |
Chlamydia trachomatis | DNA gyrase subunit A | 0.0089 | 0.1256 | 0.1849 |
Plasmodium vivax | DNA gyrase subunit B, putative | 0.016 | 0.2824 | 0.2824 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0077 | 0.1006 | 0.1006 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0148 | 0.0148 |
Schistosoma mansoni | prokaryotic DNA topoisomerase | 0.0049 | 0.0382 | 0.0382 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0055 | 0.0526 | 0.0526 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0077 | 0.1006 | 0.1006 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0115 | 0.0115 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0114 | 0.1814 | 0.3897 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0449 | 0.0449 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0051 | 0.042 | 0.042 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0077 | 0.1006 | 0.1006 |
Mycobacterium tuberculosis | DNA gyrase (subunit A) GyrA (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) | 0.0089 | 0.1256 | 0.2616 |
Plasmodium vivax | thioredoxin reductase, putative | 0.005 | 0.0405 | 0.0405 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0049 | 0.0378 | 0.0378 |
Echinococcus multilocularis | geminin | 0.0173 | 0.3115 | 0.3115 |
Schistosoma mansoni | tar DNA-binding protein | 0.0207 | 0.3863 | 0.3863 |
Loa Loa (eye worm) | DNA topoisomerase III beta-1 | 0.0049 | 0.0382 | 0.0382 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0114 | 0.1814 | 0.3897 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0055 | 0.0524 | 0.0524 |
Loa Loa (eye worm) | hypothetical protein | 0.0215 | 0.4033 | 0.4033 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0051 | 0.042 | 0.07 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.0115 | 0.0115 |
Mycobacterium ulcerans | glutaminase | 0.0272 | 0.529 | 1 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.1006 | 0.1723 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0038 | 0.0138 | 0.0138 |
Trichomonas vaginalis | DNA topoisomerase II, putative | 0.0486 | 1 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0115 | 0.0115 |
Schistosoma mansoni | hypothetical protein | 0.0173 | 0.3115 | 0.3115 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0049 | 0.0378 | 0.0378 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.005 | 0.0405 | 0.0405 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0049 | 0.0378 | 0.0378 |
Brugia malayi | TAR-binding protein | 0.0207 | 0.3863 | 0.3863 |
Mycobacterium ulcerans | DNA gyrase subunit A | 0.0089 | 0.1256 | 0.2205 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0192 | 0.3531 | 0.3531 |
Toxoplasma gondii | DNA topoisomerase 2, putative | 0.0486 | 1 | 1 |
Trypanosoma brucei | DNA topoisomerase ii | 0.0382 | 0.7715 | 0.8646 |
Leishmania major | DNA topoisomerase 1A | 0.0049 | 0.0382 | 0.0303 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0138 | 0.0138 |
Trypanosoma cruzi | DNA topoisomerase II, putative | 0.0437 | 0.8923 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0114 | 0.1814 | 0.3897 |
Toxoplasma gondii | DNA gyrase/topoisomerase IV, A subunit domain-containing protein | 0.0089 | 0.1256 | 0.1256 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0051 | 0.042 | 0.07 |
Entamoeba histolytica | DNA topoisomerase III, putative | 0.0049 | 0.0382 | 0.0237 |
Plasmodium falciparum | DNA topoisomerase 3, putative | 0.0049 | 0.0382 | 0.0382 |
Plasmodium falciparum | glutathione reductase | 0.005 | 0.0405 | 0.0405 |
Wolbachia endosymbiont of Brugia malayi | DNA gyrase, topoisomerase II, B subunit, GyrB | 0.016 | 0.2824 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0207 | 0.3863 | 0.3863 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 0.0449 | 0.0449 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.1006 | 0.2557 |
Trypanosoma cruzi | DNA topoisomerase II, putative | 0.0437 | 0.8923 | 1 |
Trypanosoma cruzi | DNA topoisomerase IA, putative | 0.0049 | 0.0382 | 0.0303 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0115 | 0.0115 |
Echinococcus multilocularis | tar DNA binding protein | 0.0207 | 0.3863 | 0.3863 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0115 | 0.0115 |
Plasmodium vivax | glutathione reductase, putative | 0.005 | 0.0405 | 0.0405 |
Brugia malayi | hypothetical protein | 0.0038 | 0.0148 | 0.0148 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0056 | 0.0547 | 0.0547 |
Echinococcus granulosus | tar DNA binding protein | 0.0207 | 0.3863 | 0.3863 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0038 | 0.0148 | 0.0148 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0049 | 0.0378 | 0.0379 |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.0352 | 0.706 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0115 | 0.0115 |
Echinococcus granulosus | snurportin 1 | 0.0337 | 0.6724 | 0.6724 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0038 | 0.0148 | 0.0148 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0127 | 0.2094 | 0.4538 |
Echinococcus granulosus | geminin | 0.0173 | 0.3115 | 0.3115 |
Chlamydia trachomatis | DNA gyrase subunit B | 0.0264 | 0.5109 | 1 |
Echinococcus multilocularis | DNA topoisomerase 2 alpha | 0.0486 | 1 | 1 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0114 | 0.1814 | 0.8586 |
Trypanosoma cruzi | DNA topoisomerase IA, putative | 0.0049 | 0.0382 | 0.0303 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0077 | 0.1006 | 0.1006 |
Brugia malayi | RNA, U transporter 1 | 0.009 | 0.1281 | 0.1281 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0524 | 0.0524 |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.0352 | 0.706 | 1 |
Brugia malayi | Thioredoxin reductase | 0.005 | 0.0405 | 0.0405 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 0.0449 | 0.0449 |
Trichomonas vaginalis | prokaryotic DNA topoisomerase, putative | 0.0049 | 0.0382 | 0.027 |
Leishmania major | DNA topoisomerase ii | 0.0437 | 0.8923 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.