Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0065 | 0.8997 | 0.8997 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0019 | 0.1472 | 0.1062 |
Echinococcus granulosus | cathepsin l1 | 0.0012 | 0.0468 | 0.0472 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0012 | 0.0468 | 0.3182 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0019 | 0.1472 | 0.1484 |
Brugia malayi | TAR-binding protein | 0.007 | 0.9919 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0019 | 0.1472 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0019 | 0.1472 | 1 |
Onchocerca volvulus | 0.0019 | 0.1472 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.1472 | 0.1484 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.1472 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0012 | 0.0468 | 0.0472 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.1472 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0019 | 0.1472 | 0.1484 |
Brugia malayi | Cathepsin L-like precursor | 0.0012 | 0.0468 | 0.0472 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 1 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0019 | 0.1472 | 0.1484 |
Onchocerca volvulus | 0.0019 | 0.1472 | 1 | |
Echinococcus multilocularis | tar DNA binding protein | 0.007 | 0.9919 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0019 | 0.1472 | 0.1484 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0019 | 0.1472 | 0.1062 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.1472 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0019 | 0.1472 | 0.1484 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.1472 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.1472 | 0.1484 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0019 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.1472 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0019 | 0.1472 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.9919 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.1472 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.1472 | 1 |
Leishmania major | cathepsin L-like protease | 0.0071 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.9919 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.1472 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0012 | 0.0468 | 0.0472 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0071 | 1 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0019 | 0.1472 | 0.1062 |
Onchocerca volvulus | Cathepsin L homolog | 0.0019 | 0.1472 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0019 | 0.1472 | 0.1484 |
Onchocerca volvulus | 0.0019 | 0.1472 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0012 | 0.0468 | 0.3182 |
Echinococcus granulosus | tar DNA binding protein | 0.007 | 0.9919 | 1 |
Leishmania major | cathepsin L-like protease | 0.0071 | 1 | 1 |
Onchocerca volvulus | 0.0019 | 0.1472 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.1472 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.9919 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.007 | 0.9919 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.1472 | 0.1484 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.1472 | 0.1484 |
Loa Loa (eye worm) | fibroinase | 0.0019 | 0.1472 | 0.1062 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0019 | 0.1472 | 0.1472 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0019 | 0.1472 | 0.1484 |
Onchocerca volvulus | 0.0019 | 0.1472 | 1 | |
Brugia malayi | RNA binding protein | 0.007 | 0.9919 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.1472 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0012 | 0.0468 | 0.0472 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.9919 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0019 | 0.1472 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 1 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0019 | 0.1472 | 0.1484 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0012 | 0.0468 | 0.3182 |
Echinococcus multilocularis | cysteine protease | 0.0019 | 0.1472 | 0.1484 |
Onchocerca volvulus | Cathepsin F homolog | 0.0019 | 0.1472 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0019 | 0.1472 | 0.1062 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0019 | 0.1472 | 1 |
Plasmodium vivax | vivapain-2 | 0.0019 | 0.1472 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0071 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0019 | 0.1472 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.007 | 0.9919 | 1 |
Onchocerca volvulus | 0.0019 | 0.1472 | 1 | |
Loa Loa (eye worm) | TAR-binding protein | 0.007 | 0.9919 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.007 | 0.9919 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.007 | 0.9919 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0012 | 0.0468 | 0.0472 |
Toxoplasma gondii | cathepsin CPL | 0.0019 | 0.1472 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0071 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 1 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0019 | 0.1472 | 0.1484 |
Onchocerca volvulus | 0.0019 | 0.1472 | 1 | |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0019 | 0.1472 | 0.1484 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.1472 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0019 | 0.1472 | 0.1484 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.1472 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0071 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.0019 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0019 | 0.1472 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0019 | 0.1472 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.1472 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.1472 | 0.1062 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.1472 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 1 | 1 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0056 | 0.7525 | 0.7525 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.1472 | 0.1484 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.1472 | 0.1484 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.