Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | lamin dm0 | 0.003 | 0.3488 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0018 | 0.0413 | 0.0413 |
Schistosoma mansoni | intermediate filament proteins | 0.003 | 0.3488 | 0.5971 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0413 | 0.0413 |
Echinococcus granulosus | lamin | 0.003 | 0.3488 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.003 | 0.3488 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0018 | 0.0413 | 0.0413 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0039 | 0.5563 | 0.5563 |
Schistosoma mansoni | lamin | 0.003 | 0.3488 | 0.5971 |
Onchocerca volvulus | 0.003 | 0.3488 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.3488 | 0.3488 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0018 | 0.0413 | 0.0413 |
Echinococcus multilocularis | lamin | 0.003 | 0.3488 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.5563 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.5563 | 0.5563 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.003 | 0.3488 | 0.3488 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.335 | 0.335 |
Loa Loa (eye worm) | intermediate filament protein | 0.003 | 0.3488 | 0.3488 |
Brugia malayi | intermediate filament protein | 0.003 | 0.3488 | 0.3488 |
Echinococcus granulosus | intermediate filament protein | 0.003 | 0.3488 | 1 |
Onchocerca volvulus | 0.003 | 0.3488 | 0.5 | |
Brugia malayi | Intermediate filament tail domain containing protein | 0.003 | 0.3488 | 0.3488 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0057 | 1 | 1 |
Echinococcus multilocularis | musashi | 0.003 | 0.3488 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0057 | 1 | 1 |
Schistosoma mansoni | lamin | 0.003 | 0.3488 | 0.5971 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.