Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | intermediate filament protein | 0.0027 | 0.3493 | 0.3493 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.3493 | 0.3493 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.3493 | 0.3493 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0409 | 0.0409 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.3493 | 0.3493 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0409 | 0.0409 |
Echinococcus multilocularis | lamin | 0.0027 | 0.3493 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 1 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.3493 | 1 |
Onchocerca volvulus | 0.0027 | 0.3493 | 0.5 | |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.5561 | 0.5561 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.3493 | 0.3493 |
Schistosoma mansoni | lamin | 0.0027 | 0.3493 | 0.5986 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.3493 | 1 |
Echinococcus granulosus | lamin | 0.0027 | 0.3493 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0409 | 0.0409 |
Schistosoma mansoni | lamin | 0.0027 | 0.3493 | 0.5986 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.3355 | 0.3355 |
Onchocerca volvulus | 0.0027 | 0.3493 | 0.5 | |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.3493 | 0.5986 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.5561 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.5561 | 0.5561 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 1 | 1 |
Echinococcus multilocularis | musashi | 0.0027 | 0.3493 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 1 | 1 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.3493 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0409 | 0.0409 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.