Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | lamin dm0 | 0.0028 | 0.3489 | 0.6311 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.5287 | 0.9466 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.5287 | 0.5 |
Onchocerca volvulus | 0.0028 | 0.3489 | 0.5 | |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.3489 | 0.3489 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0412 | 0.0412 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.5287 | 1 |
Schistosoma mansoni | lamin | 0.0028 | 0.3489 | 0.5974 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0053 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.5287 | 0.5 |
Echinococcus multilocularis | lamin | 0.0028 | 0.3489 | 0.6311 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.5562 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.5287 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.5287 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.5562 | 0.5562 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.5287 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.5562 | 0.5562 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.5287 | 0.9466 |
Brugia malayi | intermediate filament protein | 0.0028 | 0.3489 | 0.3489 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0412 | 0.0412 |
Schistosoma mansoni | intermediate filament proteins | 0.0028 | 0.3489 | 0.5974 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 0.3489 | 0.3489 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.3351 | 0.3351 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.3489 | 0.3489 |
Echinococcus granulosus | lamin | 0.0028 | 0.3489 | 0.6311 |
Onchocerca volvulus | 0.0028 | 0.3489 | 0.5 | |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0412 | 0.0412 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 0.3489 | 0.6311 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.3489 | 0.3489 |
Schistosoma mansoni | lamin | 0.0028 | 0.3489 | 0.5974 |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 0.3489 | 0.6311 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0412 | 0.0412 |
Echinococcus multilocularis | musashi | 0.0028 | 0.3489 | 0.6311 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0053 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0035 | 0.5287 | 0.5287 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.