Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.082 | 0.5 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0.082 | 0.5 |
Echinococcus multilocularis | dna polymerase eta | 0.0019 | 0.082 | 0.082 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.3716 | 0.3716 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.082 | 0.5 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.082 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.3716 | 0.3716 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.082 | 0.082 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.3716 | 0.3716 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.082 | 0.5 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0019 | 0.082 | 0.5 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0019 | 0.082 | 0.5 |
Echinococcus granulosus | dna polymerase kappa | 0.0019 | 0.082 | 0.082 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.082 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.082 | 0.5 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0019 | 0.082 | 0.082 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0019 | 0.082 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.082 | 0.5 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.082 | 0.5 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0048 | 0.6919 | 0.6919 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 1 | 1 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0019 | 0.082 | 0.082 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.082 | 0.082 |
Giardia lamblia | DINP protein human, muc B family | 0.0019 | 0.082 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.082 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0048 | 0.6919 | 0.6919 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0019 | 0.082 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.082 | 0.5 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0019 | 0.082 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.082 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0.082 | 0.5 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.082 | 0.082 |
Echinococcus granulosus | dna polymerase eta | 0.0019 | 0.082 | 0.082 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.082 | 0.5 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 1 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.082 | 0.5 |
Leishmania major | DNA polymerase kappa, putative | 0.0019 | 0.082 | 0.5 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0.082 | 0.5 |
Schistosoma mansoni | DNA polymerase eta | 0.0019 | 0.082 | 0.082 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 1 | 1 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0019 | 0.082 | 0.082 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 1 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 1 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0019 | 0.082 | 0.082 |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 1 | 1 |
Echinococcus multilocularis | dna polymerase kappa | 0.0019 | 0.082 | 0.082 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.6919 | 0.6919 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0048 | 0.6919 | 0.6919 |
Trypanosoma brucei | unspecified product | 0.0019 | 0.082 | 0.5 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.082 | 0.5 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.082 | 0.5 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0019 | 0.082 | 0.082 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0.082 | 0.5 |
Leishmania major | DNA polymerase eta, putative | 0.0019 | 0.082 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0.082 | 0.5 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0019 | 0.082 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 1 | 1 |
Brugia malayi | TAR-binding protein | 0.0063 | 1 | 1 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0.082 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.