Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | microtubule associated protein 2 | 0.2121 | 1 | 1 |
Echinococcus granulosus | intermediate filament protein | 0.0121 | 0.0336 | 0.0336 |
Echinococcus multilocularis | GPCR, family 2 | 0.0065 | 0.0066 | 0.0066 |
Echinococcus multilocularis | musashi | 0.0121 | 0.0336 | 0.0336 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0128 | 0.0371 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0119 | 0.0325 | 0.0959 |
Echinococcus granulosus | lamin dm0 | 0.0121 | 0.0336 | 0.0336 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.0336 | 0.0991 |
Echinococcus granulosus | GPCR family 2 | 0.0065 | 0.0066 | 0.0066 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0753 | 0.3389 | 1 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0059 | 0.0036 | 0.0036 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0058 | 0.0034 | 0.0034 |
Loa Loa (eye worm) | intermediate filament protein | 0.0121 | 0.0336 | 0.0991 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0121 | 0.0336 | 0.0991 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0065 | 0.0066 | 0.0066 |
Schistosoma mansoni | hypothetical protein | 0.014 | 0.0431 | 0.0431 |
Schistosoma mansoni | tar DNA-binding protein | 0.0662 | 0.2951 | 0.2951 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0034 | 0.01 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0205 | 0.0745 | 0.2197 |
Echinococcus multilocularis | tumor protein p63 | 0.1845 | 0.8666 | 0.8666 |
Loa Loa (eye worm) | RNA binding protein | 0.0662 | 0.2951 | 0.8706 |
Plasmodium vivax | SET domain protein, putative | 0.0061 | 0.0046 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0662 | 0.2951 | 0.2951 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.027 | 0.1057 | 0.1057 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0065 | 0.0065 | 0.0191 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0061 | 0.0046 | 0.0046 |
Loa Loa (eye worm) | TAR-binding protein | 0.0662 | 0.2951 | 0.8706 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0065 | 0.0066 | 0.0066 |
Onchocerca volvulus | 0.0121 | 0.0336 | 0.1418 | |
Onchocerca volvulus | 0.027 | 0.1057 | 0.4951 | |
Schistosoma mansoni | tar DNA-binding protein | 0.0662 | 0.2951 | 0.2951 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0065 | 0.0066 | 0.0195 |
Schistosoma mansoni | lamin | 0.0121 | 0.0336 | 0.0336 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0065 | 0.0066 | 0.0066 |
Loa Loa (eye worm) | hypothetical protein | 0.027 | 0.1057 | 0.3118 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0066 | 0.0066 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0058 | 0.0034 | 0.0034 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0065 | 0.0066 | 0.0195 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0205 | 0.0745 | 0.2197 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0121 | 0.0336 | 0.0991 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0061 | 0.0046 | 0.0046 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0066 | 0.0195 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0128 | 0.0371 | 1 |
Brugia malayi | TAR-binding protein | 0.0662 | 0.2951 | 0.8706 |
Schistosoma mansoni | intermediate filament proteins | 0.0121 | 0.0336 | 0.0336 |
Brugia malayi | Pre-SET motif family protein | 0.0425 | 0.1804 | 0.5322 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0205 | 0.0745 | 0.2197 |
Schistosoma mansoni | tar DNA-binding protein | 0.0662 | 0.2951 | 0.2951 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.0431 | 0.127 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0061 | 0.0046 | 0.0046 |
Echinococcus granulosus | lamin | 0.0121 | 0.0336 | 0.0336 |
Onchocerca volvulus | 0.0121 | 0.0336 | 0.1418 | |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0065 | 0.0066 | 0.0195 |
Brugia malayi | MH2 domain containing protein | 0.0753 | 0.3389 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0662 | 0.2951 | 0.2951 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0753 | 0.3389 | 1 |
Echinococcus granulosus | tumor protein p63 | 0.1845 | 0.8666 | 0.8666 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0662 | 0.2951 | 0.8706 |
Echinococcus granulosus | tar DNA binding protein | 0.0662 | 0.2951 | 0.2951 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0128 | 0.0371 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0046 | 0.0137 |
Schistosoma mansoni | lamin | 0.0121 | 0.0336 | 0.0336 |
Echinococcus multilocularis | tar DNA binding protein | 0.0662 | 0.2951 | 0.2951 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0066 | 0.0066 |
Brugia malayi | intermediate filament protein | 0.0121 | 0.0336 | 0.0991 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0061 | 0.0046 | 0.0046 |
Brugia malayi | Pre-SET motif family protein | 0.0061 | 0.0046 | 0.0137 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0023 | 0.0068 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0061 | 0.0046 | 0.0046 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.014 | 0.0431 | 0.127 |
Echinococcus multilocularis | lamin | 0.0121 | 0.0336 | 0.0336 |
Echinococcus multilocularis | lamin dm0 | 0.0121 | 0.0336 | 0.0336 |
Onchocerca volvulus | 0.0483 | 0.2087 | 1 | |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0128 | 0.0371 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0061 | 0.0046 | 0.5 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0061 | 0.0046 | 0.0046 |
Schistosoma mansoni | microtubule-associated protein tau | 0.2121 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0066 | 0.0066 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0662 | 0.2951 | 0.8706 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0065 | 0.0065 | 0.0191 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0066 | 0.0066 |
Brugia malayi | RNA binding protein | 0.0662 | 0.2951 | 0.8706 |
Trichomonas vaginalis | set domain proteins, putative | 0.0483 | 0.2087 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0023 | 0.0068 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0061 | 0.0046 | 0.0046 |
Loa Loa (eye worm) | hypothetical protein | 0.0205 | 0.0745 | 0.2197 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0425 | 0.1804 | 0.5322 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0065 | 0.0066 | 0.0066 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.