Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | glutathione reductase | 0.0116 | 0.1001 | 0.2803 |
Brugia malayi | MH2 domain containing protein | 0.0012 | 0.0022 | 0.0061 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.0072 | 0.0192 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0337 | 0.3097 | 0.8419 |
Loa Loa (eye worm) | pyridine nucleotide-disufhide oxidoreductase | 0.0031 | 0.0198 | 0.054 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0012 | 0.0022 | 0.0058 |
Brugia malayi | MH2 domain containing protein | 0.0396 | 0.3653 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0116 | 0.1001 | 0.2803 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0116 | 0.1001 | 0.2803 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0085 | 0.0711 | 0.1946 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0116 | 0.1001 | 0.2803 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0116 | 0.1001 | 0.2803 |
Schistosoma mansoni | sulfide quinone reductase | 0.0031 | 0.0198 | 0.0176 |
Onchocerca volvulus | 0.0048 | 0.0362 | 0.1523 | |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0761 | 0.7101 | 0.8958 |
Echinococcus granulosus | glutamate synthase | 0.0031 | 0.0198 | 0.0537 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0235 | 0.2132 | 0.9402 |
Schistosoma mansoni | smad | 0.0027 | 0.0163 | 0.0141 |
Brugia malayi | TAR-binding protein | 0.0276 | 0.2521 | 0.6902 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0209 | 0.057 |
Onchocerca volvulus | 0.0028 | 0.0173 | 0.0675 | |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0116 | 0.1001 | 0.2803 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0276 | 0.2521 | 0.6901 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.0157 | 0.0424 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0072 | 0.0192 |
Plasmodium vivax | SET domain protein, putative | 0.0032 | 0.0209 | 0.0037 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0042 | 0.0302 | 0.0819 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0116 | 0.1001 | 0.2803 |
Echinococcus granulosus | pyridine nucleotide disulfide oxidoreductase | 0.0031 | 0.0198 | 0.0537 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0037 | 0.0261 | 0.0714 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0072 | 0.0193 |
Loa Loa (eye worm) | nuclear factor I | 0.0015 | 0.0049 | 0.0132 |
Echinococcus multilocularis | NADPH:adrenodoxin oxidoreductase | 0.0031 | 0.0198 | 0.0537 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0042 | 0.0302 | 0.0819 |
Echinococcus granulosus | tar DNA binding protein | 0.0276 | 0.2521 | 0.6854 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0052 | 0.04 | 0.2509 |
Schistosoma mansoni | sulfide quinone reductase | 0.0031 | 0.0198 | 0.0176 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0052 | 0.04 | 0.0261 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0334 | 0.3062 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0261 | 0.0712 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.0188 | 0.0509 |
Echinococcus multilocularis | apoptosis inducing factor 1 mitochondrial | 0.0031 | 0.0198 | 0.0537 |
Entamoeba histolytica | thioredoxin reductase, putative | 0.0031 | 0.0198 | 0.5 |
Entamoeba histolytica | pyridine nucleotide-disulfide oxidoreductase family protein | 0.0031 | 0.0198 | 0.5 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0846 | 0.7904 | 1 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0027 | 0.0163 | 0.0141 |
Schistosoma mansoni | tar DNA-binding protein | 0.0276 | 0.2521 | 0.2505 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0048 | 0.0362 | 0.0341 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0116 | 0.1001 | 0.2803 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0154 | 0.1367 | 0.6024 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0116 | 0.1001 | 0.2803 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0116 | 0.1001 | 1 |
Echinococcus granulosus | mothers against decapentaplegic 2 | 0.0012 | 0.0022 | 0.0058 |
Loa Loa (eye worm) | TAR-binding protein | 0.0276 | 0.2521 | 0.6901 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0116 | 0.1001 | 1 |
Echinococcus granulosus | sulfide:quinone oxidoreductase | 0.0031 | 0.0198 | 0.0537 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0116 | 0.1001 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0072 | 0.0192 |
Echinococcus multilocularis | mothers against decapentaplegic 6 | 0.0012 | 0.0022 | 0.0058 |
Plasmodium falciparum | glutathione reductase | 0.0334 | 0.3062 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0276 | 0.2521 | 0.6902 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.0157 | 0.0424 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0116 | 0.1001 | 0.3903 |
Schistosoma mansoni | Smad4 | 0.0027 | 0.0163 | 0.0141 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0116 | 0.1001 | 0.2803 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0014 | 0.0041 | 0.0113 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0032 | 0.0209 | 0.0566 |
Echinococcus multilocularis | musashi | 0.0026 | 0.0157 | 0.0424 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0154 | 0.1367 | 0.5684 |
Toxoplasma gondii | thioredoxin reductase | 0.0334 | 0.3062 | 1 |
Loa Loa (eye worm) | glutathione reductase | 0.0334 | 0.3062 | 0.838 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0042 | 0.0302 | 0.028 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0198 | 0.0176 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0072 | 0.0193 |
Mycobacterium tuberculosis | Probable reductase | 0.0761 | 0.7101 | 0.8958 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0761 | 0.7101 | 0.8958 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0188 | 0.0166 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0173 | 0.0474 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0085 | 0.0711 | 0.1946 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.0157 | 0.0135 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0116 | 0.1001 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0042 | 0.0302 | 0.0824 |
Echinococcus multilocularis | sulfide:quinone oxidoreductase | 0.0031 | 0.0198 | 0.0537 |
Plasmodium vivax | glutathione reductase, putative | 0.0334 | 0.3062 | 1 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0116 | 0.1001 | 0.2803 |
Brugia malayi | MH1 domain containing protein | 0.0015 | 0.0049 | 0.0135 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0116 | 0.1001 | 0.2719 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0761 | 0.7101 | 0.8958 |
Entamoeba histolytica | glutamate synthase beta subunit, putative | 0.0031 | 0.0198 | 0.5 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0032 | 0.0209 | 0.0566 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0028 | 0.0074 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.0041 | 0.0111 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0116 | 0.1001 | 0.2803 |
Plasmodium falciparum | thioredoxin reductase | 0.0116 | 0.1001 | 0.2803 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0154 | 0.1367 | 0.5684 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0173 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0157 | 0.0427 |
Schistosoma mansoni | tar DNA-binding protein | 0.0276 | 0.2521 | 0.2505 |
Trypanosoma brucei | trypanothione reductase | 0.0334 | 0.3062 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0055 | 0.0424 | 0.1161 |
Trichomonas vaginalis | set domain proteins, putative | 0.0248 | 0.2255 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0072 | 0.0049 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0116 | 0.1001 | 0.2803 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0116 | 0.1001 | 1 |
Brugia malayi | MH1 domain containing protein | 0.0027 | 0.0163 | 0.0447 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0116 | 0.1001 | 0.3903 |
Brugia malayi | RNA binding protein | 0.0276 | 0.2521 | 0.6902 |
Schistosoma mansoni | glutamate synthase | 0.0031 | 0.0198 | 0.0176 |
Loa Loa (eye worm) | programmed cell death 8 | 0.0031 | 0.0198 | 0.054 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0072 | 0.0196 |
Loa Loa (eye worm) | Smad1 | 0.0027 | 0.0163 | 0.0445 |
Brugia malayi | MH2 domain containing protein | 0.0027 | 0.0163 | 0.0447 |
Schistosoma mansoni | hypothetical protein | 0.0399 | 0.3678 | 0.3664 |
Echinococcus granulosus | lamin | 0.0026 | 0.0157 | 0.0424 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0761 | 0.7101 | 0.8958 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0052 | 0.04 | 0.1084 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0235 | 0.2132 | 0.9402 |
Schistosoma mansoni | tar DNA-binding protein | 0.0276 | 0.2521 | 0.2505 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0761 | 0.7101 | 0.8958 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0846 | 0.7904 | 1 |
Brugia malayi | Thioredoxin reductase | 0.0334 | 0.3062 | 0.8381 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0116 | 0.1001 | 0.2803 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.0072 | 0.0192 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0116 | 0.1001 | 0.2803 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0052 | 0.04 | 0.0378 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0154 | 0.1367 | 0.5684 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0396 | 0.3653 | 1 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0399 | 0.3678 | 1 |
Echinococcus granulosus | dnaJ subfamily B | 0.0399 | 0.3678 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0362 | 0.0989 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0116 | 0.1001 | 1 |
Entamoeba histolytica | NAD(FAD)-dependent dehydrogenase, putative | 0.0031 | 0.0198 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0846 | 0.7904 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0042 | 0.0302 | 0.028 |
Loa Loa (eye worm) | RNA binding protein | 0.0276 | 0.2521 | 0.6901 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0072 | 0.0192 |
Schistosoma mansoni | tar DNA-binding protein | 0.0276 | 0.2521 | 0.2505 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0032 | 0.0209 | 0.0037 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0154 | 0.1367 | 0.5684 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0154 | 0.1367 | 0.5684 |
Schistosoma mansoni | glutamate synthase | 0.0031 | 0.0198 | 0.0176 |
Echinococcus multilocularis | pyridine nucleotide disulfide oxidoreductase | 0.0031 | 0.0198 | 0.0537 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0072 | 0.0192 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0424 | 0.1159 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0116 | 0.1001 | 0.2803 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.0157 | 0.0429 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0116 | 0.1001 | 0.1042 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0027 | 0.0163 | 0.0442 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0032 | 0.0209 | 0.0566 |
Echinococcus granulosus | smad | 0.0027 | 0.0163 | 0.0442 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0055 | 0.0424 | 0.1161 |
Brugia malayi | NADPH:adrenodoxin oxidoreductase, mitochondrial precursor | 0.0031 | 0.0198 | 0.0543 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0031 | 0.0198 | 0.0537 |
Brugia malayi | Smad1 | 0.0027 | 0.0163 | 0.0447 |
Echinococcus granulosus | apoptosis inducing factor 1 mitochondrial | 0.0031 | 0.0198 | 0.0537 |
Entamoeba histolytica | dihydropyrimidine dehydrogenase, putative | 0.0031 | 0.0198 | 0.5 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0027 | 0.0163 | 0.0442 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0072 | 0.0196 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0116 | 0.1001 | 1 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0235 | 0.2132 | 0.5834 |
Leishmania major | trypanothione reductase | 0.0334 | 0.3062 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0055 | 0.0424 | 0.1159 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0116 | 0.1001 | 0.2803 |
Schistosoma mansoni | smad1 5 8 and | 0.0027 | 0.0163 | 0.0141 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0188 | 0.0166 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0396 | 0.3653 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0072 | 0.0049 |
Schistosoma mansoni | smad1 5 8 and | 0.0027 | 0.0163 | 0.0141 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0042 | 0.0302 | 0.0827 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0052 | 0.04 | 0.0703 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0116 | 0.1001 | 0.2803 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0042 | 0.0302 | 0.0819 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.003 | 0.0192 | 0.052 |
Brugia malayi | Pre-SET motif family protein | 0.0218 | 0.1971 | 0.5394 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0218 | 0.1971 | 0.5393 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0235 | 0.2132 | 0.9402 |
Schistosoma mansoni | lamin | 0.0026 | 0.0157 | 0.0135 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0334 | 0.3062 | 1 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0116 | 0.1001 | 0.2803 |
Echinococcus multilocularis | Smad4 | 0.0027 | 0.0163 | 0.0442 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0027 | 0.0163 | 0.0442 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0209 | 0.0187 |
Plasmodium falciparum | thioredoxin reductase | 0.0334 | 0.3062 | 1 |
Echinococcus granulosus | NADPH:adrenodoxin oxidoreductase | 0.0031 | 0.0198 | 0.0537 |
Brugia malayi | MH1 domain containing protein | 0.0015 | 0.0049 | 0.0135 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0235 | 0.2132 | 0.9402 |
Echinococcus multilocularis | lamin | 0.0026 | 0.0157 | 0.0424 |
Echinococcus granulosus | tumor protein p63 | 0.0328 | 0.3011 | 0.8185 |
Brugia malayi | Pre-SET motif family protein | 0.0032 | 0.0209 | 0.0572 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0152 | 0.0414 |
Onchocerca volvulus | 0.0026 | 0.0157 | 0.0603 | |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0031 | 0.0198 | 0.0537 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0116 | 0.1001 | 0.274 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0163 | 0.1446 | 0.6066 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0116 | 0.1001 | 0.2803 |
Entamoeba histolytica | glutamate synthase beta subunit, putative | 0.0031 | 0.0198 | 0.5 |
Echinococcus granulosus | Smad4 | 0.0027 | 0.0163 | 0.0442 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0116 | 0.1001 | 0.2803 |
Echinococcus multilocularis | tar DNA binding protein | 0.0276 | 0.2521 | 0.6854 |
Brugia malayi | MH2 domain containing protein | 0.0027 | 0.0163 | 0.0447 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0024 | 0.0062 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0334 | 0.3062 | 0.838 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0042 | 0.0302 | 0.0819 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0049 | 0.0132 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0052 | 0.04 | 0.2509 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0052 | 0.04 | 0.1084 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0027 | 0.0163 | 0.0442 |
Brugia malayi | glutathione reductase | 0.0334 | 0.3062 | 0.8381 |
Echinococcus granulosus | mothers against decapentaplegic 6 | 0.0012 | 0.0022 | 0.0058 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0261 | 0.0239 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0022 | 0.0058 |
Onchocerca volvulus | 0.0032 | 0.0209 | 0.0836 | |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0154 | 0.1367 | 0.5684 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0061 | 0.0481 | 0.0459 |
Entamoeba histolytica | disulphide oxidoreductase, putative | 0.0031 | 0.0198 | 0.5 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0027 | 0.0163 | 0.0445 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0031 | 0.0198 | 0.0543 |
Echinococcus multilocularis | smad | 0.0027 | 0.0163 | 0.0442 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0027 | 0.0163 | 0.0445 |
Brugia malayi | MH1 domain containing protein | 0.0027 | 0.0163 | 0.0447 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0846 | 0.7904 | 1 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0761 | 0.7101 | 0.8958 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0157 | 0.0427 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0116 | 0.1001 | 0.2803 |
Brugia malayi | mothers against decapentaplegic homolog 3 | 0.0012 | 0.0022 | 0.0061 |
Echinococcus multilocularis | mothers against decapentaplegic 2 | 0.0012 | 0.0022 | 0.0058 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0048 | 0.0367 | 0.1001 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0116 | 0.1001 | 0.2803 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0173 | 0.0471 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0024 | 0.0062 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.0157 | 0.0429 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0116 | 0.1001 | 0.0981 |
Schistosoma mansoni | smad1 5 8 and | 0.0027 | 0.0163 | 0.0141 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0072 | 0.0049 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0154 | 0.1367 | 0.5684 |
Onchocerca volvulus | 0.0031 | 0.0198 | 0.0788 | |
Echinococcus multilocularis | glutamate synthase | 0.0031 | 0.0198 | 0.0537 |
Onchocerca volvulus | 0.0026 | 0.0157 | 0.0603 | |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0031 | 0.0198 | 0.0543 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0031 | 0.0198 | 0.0537 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0334 | 0.3062 | 0.3716 |
Treponema pallidum | NADH oxidase | 0.0116 | 0.1001 | 1 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0031 | 0.0198 | 0.0537 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0337 | 0.3097 | 0.8419 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0235 | 0.2132 | 0.9402 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0116 | 0.1001 | 0.2719 |
Schistosoma mansoni | disulfide oxidoreductase | 0.0031 | 0.0198 | 0.0176 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0013 | 0.0028 | 0.0074 |
Schistosoma mansoni | lamin | 0.0026 | 0.0157 | 0.0135 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.0188 | 0.0509 |
Schistosoma mansoni | glutamate synthase | 0.0031 | 0.0198 | 0.0176 |
Onchocerca volvulus | 0.0248 | 0.2255 | 1 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0042 | 0.0302 | 0.028 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0032 | 0.0209 | 0.0187 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0116 | 0.1001 | 0.2803 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0198 | 0.054 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0157 | 0.0427 |
Schistosoma mansoni | tar DNA-binding protein | 0.0276 | 0.2521 | 0.2505 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0013 | 0.0028 | 0.0074 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0235 | 0.2132 | 0.5835 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0235 | 0.2132 | 0.9402 |
Brugia malayi | glutamate synthase | 0.0031 | 0.0198 | 0.0543 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0012 | 0.0022 | 0.0058 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0209 | 0.0187 |
Echinococcus multilocularis | tumor protein p63 | 0.0328 | 0.3011 | 0.8185 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0163 | 0.1446 | 0.6066 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.0157 | 0.0424 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.0209 | 0.0187 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0072 | 0.0049 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0054 | 0.0421 | 0.0776 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0052 | 0.04 | 0.1094 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.