Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0057 | 0.0819 | 1 |
Brugia malayi | glutathione reductase | 0.0163 | 0.2923 | 0.6507 |
Schistosoma mansoni | zinc finger protein | 0.0016 | 0.0018 | 0.0018 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.0249 | 0.3044 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0415 | 0.7866 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.039 | 0.4756 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.039 | 0.4756 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0232 | 0.0232 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0232 | 0.0517 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.0302 | 0.3691 |
Schistosoma mansoni | smad1 5 8 and | 0.0017 | 0.003 | 0.003 |
Treponema pallidum | NADH oxidase | 0.0057 | 0.0819 | 1 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0037 | 0.0438 | 0.1499 |
Trypanosoma brucei | ISWI complex protein | 0.0016 | 0.0018 | 0.0061 |
Plasmodium vivax | glutathione reductase, putative | 0.0163 | 0.2923 | 1 |
Echinococcus granulosus | Smad4 | 0.0017 | 0.003 | 0.0102 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0057 | 0.0819 | 1 |
Echinococcus granulosus | zinc finger protein | 0.002 | 0.0106 | 0.0357 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.1155 | 0.2571 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0232 | 0.0517 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0437 | 0.5337 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.0255 | 0.311 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0057 | 0.0819 | 0.2803 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0057 | 0.0819 | 0.2803 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0057 | 0.0819 | 0.2803 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0016 | 0.0013 | 0.0029 |
Schistosoma mansoni | lamin | 0.0027 | 0.0232 | 0.0232 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0232 | 0.0517 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0232 | 0.0786 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0202 | 0.2462 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0017 | 0.003 | 0.0102 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.039 | 0.4756 |
Leishmania major | hypothetical protein, conserved | 0.0016 | 0.0018 | 0.0061 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.039 | 0.4756 |
Brugia malayi | MH2 domain containing protein | 0.0017 | 0.003 | 0.0067 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0062 | 0.0929 | 0.3145 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.039 | 0.4756 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0017 | 0.003 | 0.0102 |
Trypanosoma brucei | trypanothione reductase | 0.0163 | 0.2923 | 1 |
Schistosoma mansoni | smad1 5 8 and | 0.0017 | 0.003 | 0.003 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0037 | 0.0441 | 0.1494 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0047 | 0.0626 | 0.212 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0057 | 0.0819 | 0.2803 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0415 | 0.7866 | 1 |
Onchocerca volvulus | 0.0027 | 0.0232 | 1 | |
Brugia malayi | MH1 domain containing protein | 0.0017 | 0.003 | 0.0067 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0057 | 0.0819 | 0.2803 |
Schistosoma mansoni | smad | 0.0017 | 0.003 | 0.003 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0057 | 0.0819 | 0.2803 |
Echinococcus multilocularis | zinc finger protein | 0.002 | 0.0106 | 0.0357 |
Brugia malayi | MH2 domain containing protein | 0.0017 | 0.003 | 0.0067 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0057 | 0.0819 | 0.2803 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0437 | 0.5337 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0042 | 0.0523 | 0.1165 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0017 | 0.003 | 0.003 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0018 | 0.0054 | 0.0054 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0165 | 0.2953 | 1 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0017 | 0.003 | 0.0102 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0018 | 0.0054 | 0.0054 |
Plasmodium falciparum | thioredoxin reductase | 0.0057 | 0.0819 | 0.2803 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0017 | 0.003 | 0.0067 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0232 | 0.0786 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0202 | 0.2462 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.0255 | 0.311 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0232 | 0.0786 |
Loa Loa (eye worm) | glutathione reductase | 0.0163 | 0.2923 | 0.6507 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0047 | 0.0626 | 0.212 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0047 | 0.0626 | 0.7639 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0057 | 0.0819 | 0.2803 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0232 | 0.0517 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0057 | 0.0819 | 0.2803 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0047 | 0.0626 | 0.0626 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0016 | 0.0013 | 0.016 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.039 | 0.4756 |
Brugia malayi | MH2 domain containing protein | 0.0243 | 0.4492 | 1 |
Leishmania major | phosphatidylinositol 3-kinase, putative | 0.0016 | 0.0013 | 0.0045 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0018 | 0.0054 | 0.0054 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0057 | 0.0819 | 0.2803 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0232 | 0.0517 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0062 | 0.0929 | 0.3145 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0373 | 0.7047 | 0.8958 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0057 | 0.0819 | 1 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0163 | 0.2923 | 0.6507 |
Schistosoma mansoni | bromodomain containing protein | 0.0066 | 0.1002 | 0.1002 |
Echinococcus multilocularis | smad | 0.0017 | 0.003 | 0.0102 |
Trypanosoma brucei | phosphatidylinositol 3-related kinase, putative | 0.0016 | 0.0013 | 0.0045 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0018 | 0.0054 | 0.0182 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0023 | 0.0166 | 0.0564 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0018 | 0.0054 | 0.0054 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.039 | 0.4756 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0579 | 0.1289 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.004 | 0.0491 | 0.5994 |
Trypanosoma cruzi | ISWI complex protein | 0.0016 | 0.0018 | 0.0061 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0057 | 0.0819 | 0.2803 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0057 | 0.0819 | 0.2803 |
Trypanosoma cruzi | ISWI complex protein | 0.0016 | 0.0018 | 0.0061 |
Brugia malayi | PHD-finger family protein | 0.0026 | 0.0215 | 0.0479 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0373 | 0.7047 | 0.8958 |
Giardia lamblia | GTOR | 0.0047 | 0.0626 | 0.7639 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0057 | 0.0819 | 1 |
Schistosoma mansoni | Smad4 | 0.0017 | 0.003 | 0.003 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0023 | 0.0166 | 0.0564 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0243 | 0.4492 | 1 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0373 | 0.7047 | 0.8958 |
Plasmodium falciparum | thioredoxin reductase | 0.0163 | 0.2923 | 1 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0047 | 0.0626 | 0.2141 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.0016 | 0.0013 | 0.0045 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0037 | 0.0441 | 0.1494 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0018 | 0.0066 | 0.0148 |
Plasmodium falciparum | glutathione reductase | 0.0163 | 0.2923 | 1 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0016 | 0.0013 | 0.0045 |
Trypanosoma brucei | FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative | 0.0019 | 0.0087 | 0.0297 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0163 | 0.2923 | 1 |
Brugia malayi | Smad1 | 0.0017 | 0.003 | 0.0067 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0057 | 0.0819 | 0.2803 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0057 | 0.0819 | 1 |
Leishmania major | phosphatidylinositol 3-related kinase, putative | 0.0016 | 0.0013 | 0.0045 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.0047 | 0.0626 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0437 | 0.5337 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.0166 | 0.0166 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0057 | 0.0819 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.054 | 0.1201 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0047 | 0.0626 | 0.7639 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0057 | 0.0819 | 0.2775 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0223 | 0.0495 |
Onchocerca volvulus | 0.0027 | 0.0232 | 1 | |
Echinococcus multilocularis | Smad4 | 0.0017 | 0.003 | 0.0102 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0047 | 0.0626 | 0.2141 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0057 | 0.0819 | 0.2803 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0054 | 0.012 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0035 | 0.039 | 0.1333 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0037 | 0.0438 | 0.1499 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0047 | 0.0626 | 0.2141 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0201 | 0.2453 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0232 | 0.0786 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0437 | 0.5337 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.0016 | 0.0013 | 0.0044 |
Echinococcus granulosus | smad | 0.0017 | 0.003 | 0.0102 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.0255 | 0.311 |
Schistosoma mansoni | smad1 5 8 and | 0.0017 | 0.003 | 0.003 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0201 | 0.2453 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0017 | 0.003 | 0.0102 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0057 | 0.0819 | 0.2803 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0016 | 0.0013 | 0.016 |
Brugia malayi | Bromodomain containing protein | 0.0078 | 0.1243 | 0.2766 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0127 | 0.0127 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.0022 | 0.014 | 0.0479 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0232 | 0.0786 |
Mycobacterium tuberculosis | Probable reductase | 0.0373 | 0.7047 | 0.8958 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0042 | 0.0523 | 0.1165 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0047 | 0.0626 | 0.2141 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0057 | 0.0819 | 0.2775 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0415 | 0.7866 | 1 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0373 | 0.7047 | 0.8958 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0057 | 0.0819 | 0.1042 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0057 | 0.0819 | 0.0819 |
Brugia malayi | Bromodomain containing protein | 0.004 | 0.049 | 0.109 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0057 | 0.0819 | 0.2803 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0057 | 0.0819 | 1 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0047 | 0.0626 | 0.2141 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0047 | 0.0626 | 0.1393 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0491 | 0.1093 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0373 | 0.7047 | 0.8958 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0057 | 0.0819 | 1 |
Brugia malayi | MH1 domain containing protein | 0.0017 | 0.003 | 0.0067 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0016 | 0.0013 | 0.0029 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0057 | 0.0819 | 0.2803 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0057 | 0.0819 | 0.2803 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0057 | 0.0819 | 0.1824 |
Schistosoma mansoni | zinc finger protein | 0.002 | 0.0106 | 0.0106 |
Echinococcus granulosus | lamin | 0.0027 | 0.0232 | 0.0786 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0016 | 0.0013 | 0.0045 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0243 | 0.4492 | 1 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0037 | 0.0438 | 0.1499 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.0047 | 0.0626 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0028 | 0.0249 | 0.3044 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0163 | 0.2923 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0018 | 0.0018 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0057 | 0.0819 | 0.2803 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0031 | 0.0322 | 0.3934 |
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.0016 | 0.0013 | 0.0044 |
Plasmodium falciparum | glutathione reductase | 0.0057 | 0.0819 | 0.2803 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0021 | 0.0127 | 0.0283 |
Toxoplasma gondii | thioredoxin reductase | 0.0163 | 0.2923 | 1 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0163 | 0.2923 | 0.3716 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0018 | 0.0054 | 0.0182 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0047 | 0.0626 | 0.7639 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0047 | 0.0626 | 0.1393 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0016 | 0.0013 | 0.016 |
Leishmania major | trypanothione reductase | 0.0163 | 0.2923 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0018 | 0.0054 | 0.0182 |
Schistosoma mansoni | lamin | 0.0027 | 0.0232 | 0.0232 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0037 | 0.0437 | 0.5337 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0165 | 0.2953 | 1 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0017 | 0.003 | 0.0067 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.0016 | 0.0013 | 0.0013 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0202 | 0.2462 |
Loa Loa (eye worm) | Smad1 | 0.0017 | 0.003 | 0.0067 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0201 | 0.2453 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0057 | 0.0819 | 0.2803 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0057 | 0.0819 | 0.2803 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0018 | 0.0054 | 0.0182 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0025 | 0.0202 | 0.2462 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0047 | 0.0626 | 0.2141 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0057 | 0.0819 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0016 | 0.0013 | 0.016 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0016 | 0.0013 | 0.016 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0415 | 0.7866 | 1 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0057 | 0.0819 | 0.2803 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0373 | 0.7047 | 0.8958 |
Brugia malayi | Thioredoxin reductase | 0.0163 | 0.2923 | 0.6507 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0057 | 0.0819 | 0.2803 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.