Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0135 | 0.0288 | 0.0288 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0319 | 0.0924 | 0.1236 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0319 | 0.0924 | 0.2803 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0273 | 0.0766 | 0.2255 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0085 | 0.0114 | 0.1037 |
Echinococcus granulosus | tar DNA binding protein | 0.0919 | 0.3002 | 0.402 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0319 | 0.0924 | 0.0924 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0319 | 0.0924 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.0114 | 0.0195 |
Giardia lamblia | GTOR | 0.0273 | 0.0766 | 0.8045 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0135 | 0.0288 | 0.0384 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0135 | 0.0288 | 0.0384 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.2333 | 0.7893 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.0288 | 0.0498 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0217 | 0.0573 | 0.611 |
Schistosoma mansoni | tar DNA-binding protein | 0.0919 | 0.3002 | 0.3002 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0108 | 0.0195 | 0.0258 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0047 | 0.0079 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0163 | 0.0386 | 0.4042 |
Plasmodium falciparum | glutathione reductase | 0.092 | 0.3005 | 1 |
Loa Loa (eye worm) | Smad1 | 0.0117 | 0.0225 | 0.0389 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0217 | 0.0573 | 0.611 |
Echinococcus multilocularis | lamin dm0 | 0.0141 | 0.0308 | 0.0411 |
Echinococcus multilocularis | tar DNA binding protein | 0.0919 | 0.3002 | 0.402 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0233 | 0.0628 | 0.672 |
Echinococcus multilocularis | NADPH:adrenodoxin oxidoreductase | 0.0085 | 0.0114 | 0.0151 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0141 | 0.0308 | 0.0533 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0203 | 0.0524 | 0.557 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0141 | 0.0308 | 0.0533 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.0273 | 0.0766 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0203 | 0.0524 | 0.557 |
Loa Loa (eye worm) | programmed cell death 8 | 0.0085 | 0.0114 | 0.0195 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0183 | 0.0455 | 0.4807 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0085 | 0.0114 | 0.0151 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0319 | 0.0924 | 1 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0092 | 0.0138 | 0.0083 |
Trichomonas vaginalis | glutamate synthase, putative | 0.0085 | 0.0114 | 0.1037 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0919 | 0.3002 | 0.5221 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0163 | 0.0386 | 0.4042 |
Schistosoma mansoni | glutamate synthase | 0.0085 | 0.0114 | 0.0114 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0068 | 0.0056 | 0.0073 |
Trypanosoma brucei | FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative | 0.0113 | 0.0214 | 0.0344 |
Echinococcus granulosus | glutamate synthase | 0.0085 | 0.0114 | 0.0151 |
Schistosoma mansoni | tar DNA-binding protein | 0.0919 | 0.3002 | 0.3002 |
Echinococcus multilocularis | smad | 0.0117 | 0.0225 | 0.0299 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0147 | 0.0331 | 0.344 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.2099 | 0.7083 | 0.8958 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0217 | 0.0573 | 0.611 |
Onchocerca volvulus | 0.0141 | 0.0308 | 0.4362 | |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0085 | 0.0114 | 0.0151 |
Plasmodium falciparum | thioredoxin reductase | 0.0319 | 0.0924 | 0.2803 |
Onchocerca volvulus | 0.0146 | 0.0327 | 0.4632 | |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0045 | 0.0075 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0273 | 0.0766 | 0.2255 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0273 | 0.0766 | 0.8248 |
Brugia malayi | MH1 domain containing protein | 0.0065 | 0.0045 | 0.0075 |
Schistosoma mansoni | hypothetical protein | 0.0291 | 0.083 | 0.083 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0273 | 0.0766 | 0.133 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0319 | 0.0924 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0085 | 0.0114 | 0.0114 |
Schistosoma mansoni | glutamate synthase | 0.0085 | 0.0114 | 0.0114 |
Trichomonas vaginalis | glutamate synthase, putative | 0.0085 | 0.0114 | 0.1037 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.1713 | 0.5748 | 1 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0085 | 0.0114 | 0.1037 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.0308 | 0.0533 |
Brugia malayi | MH2 domain containing protein | 0.1713 | 0.5748 | 1 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0319 | 0.0924 | 1 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0085 | 0.0114 | 0.1037 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0319 | 0.0924 | 0.2803 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0217 | 0.0573 | 0.1589 |
Echinococcus granulosus | tumor protein p63 | 0.1743 | 0.5853 | 0.784 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0047 | 0.0079 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.2099 | 0.7083 | 0.8958 |
Echinococcus granulosus | apoptosis inducing factor 1 mitochondrial | 0.0085 | 0.0114 | 0.0151 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.2099 | 0.7083 | 0.8958 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.2099 | 0.7083 | 0.8958 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0319 | 0.0924 | 0.2803 |
Trypanosoma brucei | trypanothione reductase | 0.092 | 0.3005 | 1 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.2333 | 0.7893 | 1 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0319 | 0.0924 | 0.1606 |
Schistosoma mansoni | glutamate synthase | 0.0085 | 0.0114 | 0.0114 |
Schistosoma mansoni | microtubule-associated protein tau | 0.2209 | 0.7464 | 0.7464 |
Plasmodium falciparum | glutathione reductase | 0.0319 | 0.0924 | 0.2803 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0234 | 0.0631 | 0.0664 |
Loa Loa (eye worm) | TAR-binding protein | 0.0919 | 0.3002 | 0.5221 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0092 | 0.0138 | 0.0237 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0319 | 0.0924 | 0.2803 |
Echinococcus multilocularis | lamin | 0.0141 | 0.0308 | 0.0411 |
Schistosoma mansoni | intermediate filament proteins | 0.0141 | 0.0308 | 0.0308 |
Schistosoma mansoni | tar DNA-binding protein | 0.0919 | 0.3002 | 0.3002 |
Schistosoma mansoni | Smad4 | 0.0117 | 0.0225 | 0.0225 |
Entamoeba histolytica | hypothetical protein | 0.0108 | 0.0195 | 0.1235 |
Echinococcus multilocularis | glutamate synthase | 0.0085 | 0.0114 | 0.0151 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.2099 | 0.7083 | 0.8958 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0068 | 0.0056 | 0.0073 |
Brugia malayi | hypothetical protein | 0.0108 | 0.0195 | 0.0336 |
Plasmodium falciparum | thioredoxin reductase | 0.092 | 0.3005 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.024 | 0.065 | 0.6968 |
Brugia malayi | glutamate synthase | 0.0085 | 0.0114 | 0.0195 |
Loa Loa (eye worm) | hypothetical protein | 0.0426 | 0.1296 | 0.2253 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0319 | 0.0924 | 0.2803 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0319 | 0.0924 | 0.2803 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0319 | 0.0924 | 0.3029 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0073 | 0.0075 | 0.0602 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0117 | 0.0225 | 0.0389 |
Onchocerca volvulus | 0.0085 | 0.0114 | 0.1599 | |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0919 | 0.3002 | 0.5221 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0319 | 0.0924 | 0.2803 |
Trichomonas vaginalis | dihydrolipoamide dehydrogenase, putative | 0.0085 | 0.0114 | 0.1037 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0319 | 0.0924 | 0.2803 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0273 | 0.0766 | 0.8248 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0319 | 0.0924 | 0.2803 |
Trichomonas vaginalis | dihydropyrimidine dehydrogenase, putative | 0.0085 | 0.0114 | 0.1037 |
Mycobacterium tuberculosis | Probable reductase | 0.2099 | 0.7083 | 0.8958 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0147 | 0.0331 | 0.344 |
Schistosoma mansoni | Smad4 | 0.0052 | 0.0002 | 0.0002 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0085 | 0.0114 | 0.0314 |
Echinococcus granulosus | GPCR family 2 | 0.0135 | 0.0288 | 0.0384 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0319 | 0.0924 | 0.2803 |
Trypanosoma brucei | phosphatidylinositol 3-related kinase, putative | 0.0092 | 0.0138 | 0.0083 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0273 | 0.0766 | 0.2255 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0928 | 0.3031 | 0.406 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0135 | 0.0288 | 0.0384 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0203 | 0.0524 | 0.557 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.2209 | 0.7464 | 1 |
Schistosoma mansoni | disulfide oxidoreductase | 0.0085 | 0.0114 | 0.0114 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.2099 | 0.7083 | 0.8958 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0117 | 0.0225 | 0.0389 |
Brugia malayi | MH1 domain containing protein | 0.0117 | 0.0225 | 0.0389 |
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.0092 | 0.0138 | 0.0183 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0319 | 0.0924 | 0.2803 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.092 | 0.3005 | 0.3716 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0203 | 0.0524 | 0.1687 |
Loa Loa (eye worm) | thioredoxin reductase | 0.092 | 0.3005 | 0.5226 |
Schistosoma mansoni | lamin | 0.0141 | 0.0308 | 0.0308 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0319 | 0.0924 | 0.2803 |
Schistosoma mansoni | smad1 5 8 and | 0.0117 | 0.0225 | 0.0225 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0085 | 0.0114 | 0.0314 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.0273 | 0.0766 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.0327 | 0.0566 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0092 | 0.0138 | 0.1302 |
Echinococcus multilocularis | apoptosis inducing factor 1 mitochondrial | 0.0085 | 0.0114 | 0.0151 |
Schistosoma mansoni | tar DNA-binding protein | 0.0919 | 0.3002 | 0.3002 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0928 | 0.3031 | 0.406 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0085 | 0.0114 | 0.1037 |
Leishmania major | phosphatidylinositol 3-related kinase, putative | 0.0092 | 0.0138 | 0.0083 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0075 | 0.0082 | 0.014 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0085 | 0.0114 | 0.0195 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0203 | 0.0524 | 0.557 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.092 | 0.3005 | 1 |
Loa Loa (eye worm) | nuclear factor I | 0.0065 | 0.0045 | 0.0075 |
Schistosoma mansoni | tar DNA-binding protein | 0.0919 | 0.3002 | 0.3002 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0273 | 0.0766 | 0.8248 |
Schistosoma mansoni | hypothetical protein | 0.0135 | 0.0288 | 0.0288 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0117 | 0.0225 | 0.0299 |
Loa Loa (eye worm) | pyridine nucleotide-disufhide oxidoreductase | 0.0085 | 0.0114 | 0.0195 |
Schistosoma mansoni | hypothetical protein | 0.0135 | 0.0288 | 0.0288 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0092 | 0.0138 | 0.1302 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0273 | 0.0766 | 0.2255 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0273 | 0.0766 | 0.2255 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0319 | 0.0924 | 1 |
Echinococcus granulosus | intermediate filament protein | 0.0141 | 0.0308 | 0.0411 |
Toxoplasma gondii | NADH dehydrogenase (NDH2-II) | 0.0085 | 0.0114 | 0.0314 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0426 | 0.1296 | 0.2253 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0092 | 0.0138 | 0.0083 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0162 | 0.038 | 0.398 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.0092 | 0.0138 | 0.0138 |
Plasmodium vivax | glutathione reductase, putative | 0.092 | 0.3005 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0108 | 0.0195 | 0.0195 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0162 | 0.038 | 0.398 |
Brugia malayi | Thioredoxin reductase | 0.092 | 0.3005 | 0.5226 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0319 | 0.0924 | 0.1042 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0426 | 0.1296 | 0.2253 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0092 | 0.0138 | 0.0237 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0273 | 0.0766 | 0.1024 |
Toxoplasma gondii | thioredoxin reductase | 0.092 | 0.3005 | 1 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0117 | 0.0225 | 0.0299 |
Echinococcus multilocularis | tumor protein p63 | 0.1743 | 0.5853 | 0.784 |
Brugia malayi | MH1 domain containing protein | 0.0117 | 0.0225 | 0.0389 |
Echinococcus granulosus | Smad4 | 0.0117 | 0.0225 | 0.0299 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0085 | 0.0114 | 0.0151 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0075 | 0.0082 | 0.014 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0319 | 0.0924 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0203 | 0.0524 | 0.557 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0117 | 0.0225 | 0.0299 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0203 | 0.0524 | 0.557 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0234 | 0.0632 | 0.1096 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0319 | 0.0924 | 1 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0255 | 0.0704 | 0.0704 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0319 | 0.0924 | 1 |
Schistosoma mansoni | smad | 0.0052 | 0.0002 | 0.0002 |
Plasmodium vivax | thioredoxin reductase, putative | 0.092 | 0.3005 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.002 | 0.0032 |
Entamoeba histolytica | hypothetical protein | 0.0108 | 0.0195 | 0.1235 |
Brugia malayi | NADPH:adrenodoxin oxidoreductase, mitochondrial precursor | 0.0085 | 0.0114 | 0.0195 |
Schistosoma mansoni | smad1 5 8 and | 0.0117 | 0.0225 | 0.0225 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0273 | 0.0766 | 0.2255 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0014 | 0.0021 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0319 | 0.0924 | 0.3029 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0056 | 0.0095 |
Brugia malayi | MH2 domain containing protein | 0.0117 | 0.0225 | 0.0389 |
Echinococcus granulosus | smad | 0.0117 | 0.0225 | 0.0299 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.0129 | 0.0268 | 0.0533 |
Echinococcus multilocularis | musashi | 0.0141 | 0.0308 | 0.0411 |
Onchocerca volvulus | 0.024 | 0.065 | 0.9234 | |
Echinococcus granulosus | lamin dm0 | 0.0141 | 0.0308 | 0.0411 |
Schistosoma mansoni | hypothetical protein | 0.0108 | 0.0195 | 0.0195 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0108 | 0.0195 | 0.0258 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0163 | 0.0386 | 0.4042 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0273 | 0.0766 | 0.1024 |
Echinococcus multilocularis | GPCR, family 2 | 0.0135 | 0.0288 | 0.0384 |
Schistosoma mansoni | sulfide quinone reductase | 0.0085 | 0.0114 | 0.0114 |
Onchocerca volvulus | 0.0255 | 0.0704 | 1 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0092 | 0.0138 | 0.1302 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0273 | 0.0766 | 0.0766 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0319 | 0.0924 | 0.2803 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0319 | 0.0924 | 0.2803 |
Schistosoma mansoni | hypothetical protein | 0.0135 | 0.0288 | 0.0288 |
Brugia malayi | MH2 domain containing protein | 0.0117 | 0.0225 | 0.0389 |
Brugia malayi | Pre-SET motif family protein | 0.0211 | 0.055 | 0.0953 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0319 | 0.0924 | 0.2803 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.2333 | 0.7893 | 1 |
Brugia malayi | TAR-binding protein | 0.0919 | 0.3002 | 0.5221 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0085 | 0.0114 | 0.0151 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0203 | 0.0524 | 0.557 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0147 | 0.0331 | 0.344 |
Brugia malayi | RNA binding protein | 0.0919 | 0.3002 | 0.5221 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.0092 | 0.0138 | 0.0183 |
Schistosoma mansoni | sulfide quinone reductase | 0.0085 | 0.0114 | 0.0114 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0147 | 0.0331 | 0.3432 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0234 | 0.0632 | 0.1096 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0217 | 0.0573 | 0.611 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0147 | 0.0331 | 0.3432 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0319 | 0.0924 | 0.2803 |
Leishmania major | trypanothione reductase | 0.092 | 0.3005 | 1 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0085 | 0.0114 | 0.1037 |
Echinococcus granulosus | pyridine nucleotide disulfide oxidoreductase | 0.0085 | 0.0114 | 0.0151 |
Echinococcus granulosus | NADPH:adrenodoxin oxidoreductase | 0.0085 | 0.0114 | 0.0151 |
Loa Loa (eye worm) | RNA binding protein | 0.0919 | 0.3002 | 0.5221 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0319 | 0.0924 | 0.2803 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0085 | 0.0114 | 0.1037 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0319 | 0.0924 | 1 |
Echinococcus granulosus | lamin | 0.0141 | 0.0308 | 0.0411 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0211 | 0.055 | 0.0953 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0291 | 0.083 | 0.1441 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0147 | 0.0331 | 0.344 |
Brugia malayi | intermediate filament protein | 0.0141 | 0.0308 | 0.0533 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0092 | 0.0138 | 0.1302 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0085 | 0.0114 | 0.0314 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.0092 | 0.0138 | 0.0083 |
Brugia malayi | Smad1 | 0.0117 | 0.0225 | 0.0389 |
Onchocerca volvulus | 0.0141 | 0.0308 | 0.4362 | |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0426 | 0.1296 | 0.2253 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0135 | 0.0288 | 0.0498 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0319 | 0.0924 | 0.2803 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.1713 | 0.5748 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0319 | 0.0924 | 0.2803 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0319 | 0.0924 | 0.2803 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0135 | 0.0288 | 0.0498 |
Brugia malayi | hypothetical protein | 0.0146 | 0.0327 | 0.0566 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0092 | 0.0138 | 0.1302 |
Loa Loa (eye worm) | hypothetical protein | 0.0138 | 0.0299 | 0.0518 |
Brugia malayi | glutathione reductase | 0.092 | 0.3005 | 0.5226 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0135 | 0.0288 | 0.0384 |
Schistosoma mansoni | lamin | 0.0141 | 0.0308 | 0.0308 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0319 | 0.0924 | 0.1236 |
Brugia malayi | MH1 domain containing protein | 0.0065 | 0.0045 | 0.0075 |
Echinococcus granulosus | sulfide:quinone oxidoreductase | 0.0085 | 0.0114 | 0.0151 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0085 | 0.0114 | 0.1037 |
Echinococcus multilocularis | pyridine nucleotide disulfide oxidoreductase | 0.0085 | 0.0114 | 0.0151 |
Entamoeba histolytica | hypothetical protein | 0.0108 | 0.0195 | 0.1235 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0319 | 0.0924 | 0.2803 |
Toxoplasma gondii | selenide, water dikinase | 0.0085 | 0.0114 | 0.0314 |
Loa Loa (eye worm) | hypothetical protein | 0.0291 | 0.083 | 0.1441 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0085 | 0.0114 | 0.1037 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0273 | 0.0766 | 0.133 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0217 | 0.0573 | 0.1589 |
Echinococcus multilocularis | Smad4 | 0.0117 | 0.0225 | 0.0299 |
Echinococcus granulosus | microtubule associated protein 2 | 0.2209 | 0.7464 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.2333 | 0.7893 | 1 |
Leishmania major | phosphatidylinositol 3-kinase, putative | 0.0092 | 0.0138 | 0.0083 |
Loa Loa (eye worm) | intermediate filament protein | 0.0141 | 0.0308 | 0.0533 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0117 | 0.0225 | 0.0299 |
Schistosoma mansoni | Smad4 | 0.0052 | 0.0002 | 0.0002 |
Entamoeba histolytica | hypothetical protein | 0.0108 | 0.0195 | 0.1235 |
Schistosoma mansoni | smad1 5 8 and | 0.0117 | 0.0225 | 0.0225 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0135 | 0.0288 | 0.0498 |
Schistosoma mansoni | smad | 0.0117 | 0.0225 | 0.0225 |
Trichomonas vaginalis | apoptosis inducing factor, putative | 0.0085 | 0.0114 | 0.1037 |
Loa Loa (eye worm) | glutathione reductase | 0.092 | 0.3005 | 0.5226 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0147 | 0.0331 | 0.3432 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0085 | 0.0114 | 0.0195 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0177 | 0.0435 | 0.4582 |
Loa Loa (eye worm) | hypothetical protein | 0.0255 | 0.0704 | 0.1222 |
Treponema pallidum | NADH oxidase | 0.0319 | 0.0924 | 1 |
Echinococcus multilocularis | sulfide:quinone oxidoreductase | 0.0085 | 0.0114 | 0.0151 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0217 | 0.0573 | 0.611 |
Toxoplasma gondii | non-proton pumping type-II NADH dehydrogenase I | 0.0085 | 0.0114 | 0.0314 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0217 | 0.0573 | 0.1589 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0117 | 0.0225 | 0.0225 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.