Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0061 | 0.0156 | 0.1305 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0067 | 0.0185 | 0.0395 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.023 | 0.0963 | 0.3099 |
Leishmania major | hypothetical protein, conserved | 0.0061 | 0.0156 | 0.0411 |
Loa Loa (eye worm) | nuclear factor I | 0.0037 | 0.0042 | 0.0081 |
Echinococcus granulosus | NADPH:adrenodoxin oxidoreductase | 0.0061 | 0.0156 | 0.0511 |
Toxoplasma gondii | non-proton pumping type-II NADH dehydrogenase I | 0.0061 | 0.0156 | 0.0499 |
Echinococcus granulosus | glutamate synthase | 0.0061 | 0.0156 | 0.0511 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0033 | 0.0061 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.023 | 0.0963 | 1 |
Trichomonas vaginalis | glutamate synthase, putative | 0.0061 | 0.0156 | 0.1305 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.0134 | 0.0505 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.0112 | 0.0233 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0115 | 0.0411 | 0.4003 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.009 | 0.0294 | 0.2763 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0061 | 0.0156 | 0.1305 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.1517 | 0.7095 | 0.8975 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.1686 | 0.7902 | 1 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0061 | 0.0156 | 0.0332 |
Schistosoma mansoni | smad1 5 8 and | 0.0067 | 0.0185 | 0.018 |
Echinococcus multilocularis | mothers against decapentaplegic 2 | 0.003 | 0.0008 | 0.0009 |
Schistosoma mansoni | smad | 0.003 | 0.0008 | 0.0003 |
Echinococcus multilocularis | NADPH:adrenodoxin oxidoreductase | 0.0061 | 0.0156 | 0.0495 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0033 | 0.0028 |
Plasmodium vivax | NAD(P)H-dependent glutamate synthase, putative | 0.0061 | 0.0156 | 0.0499 |
Mycobacterium ulcerans | dehydrogenase | 0.0061 | 0.0156 | 0.1326 |
Mycobacterium ulcerans | NADH dehydrogenase Ndh | 0.0061 | 0.0156 | 0.1326 |
Toxoplasma gondii | selenide, water dikinase | 0.0061 | 0.0156 | 0.0499 |
Trypanosoma brucei | FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative | 0.0056 | 0.0131 | 0.0325 |
Plasmodium vivax | glutathione reductase, putative | 0.0665 | 0.3034 | 1 |
Echinococcus multilocularis | Smad4 | 0.0067 | 0.0185 | 0.0589 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0073 | 0.021 | 0.1877 |
Schistosoma mansoni | glutamate synthase | 0.0061 | 0.0156 | 0.0151 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0107 | 0.0374 | 0.3607 |
Trichomonas vaginalis | mercuric reductase, putative | 0.023 | 0.0963 | 0.9845 |
Mycobacterium tuberculosis | Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) | 0.0061 | 0.0156 | 0.0157 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.01 | 0.0341 | 0.3257 |
Onchocerca volvulus | 0.0048 | 0.0096 | 0.0933 | |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.01 | 0.0341 | 0.1108 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0061 | 0.0156 | 0.1305 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0061 | 0.0156 | 0.0411 |
Plasmodium vivax | type II NADH:ubiquinone oxidoreductase, putative | 0.0061 | 0.0156 | 0.0499 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0072 | 0.021 | 0.1871 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.01 | 0.0341 | 0.3257 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0107 | 0.0374 | 0.3607 |
Echinococcus granulosus | smad | 0.0067 | 0.0185 | 0.0605 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.023 | 0.0963 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0649 | 0.2958 | 0.2954 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.0112 | 0.0233 |
Echinococcus multilocularis | tar DNA binding protein | 0.0649 | 0.2958 | 0.9661 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0045 | 0.008 | 0.0163 |
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.0045 | 0.008 | 0.0243 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.023 | 0.0963 | 0.3099 |
Schistosoma mansoni | sulfide quinone reductase | 0.0061 | 0.0156 | 0.0151 |
Brugia malayi | beta-lactamase | 0.0035 | 0.0033 | 0.0061 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.023 | 0.0963 | 0.3099 |
Brugia malayi | MH1 domain containing protein | 0.0067 | 0.0185 | 0.0395 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.008 | 0.0247 | 0.2267 |
Giardia lamblia | GTOR | 0.0134 | 0.0505 | 0.4318 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0072 | 0.021 | 0.1871 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0067 | 0.0185 | 0.0395 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0061 | 0.0156 | 0.0332 |
Schistosoma mansoni | glutamate synthase | 0.0061 | 0.0156 | 0.0151 |
Trypanosoma cruzi | NADPH:adrenodoxin oxidoreductase, mitochondrial, putative | 0.0061 | 0.0156 | 0.0411 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0067 | 0.0185 | 0.0605 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprB | 0.0061 | 0.0156 | 0.1326 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.023 | 0.0963 | 0.3099 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.023 | 0.0963 | 0.3099 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.023 | 0.0963 | 0.3099 |
Echinococcus multilocularis | pyridine nucleotide disulfide oxidoreductase | 0.0061 | 0.0156 | 0.0495 |
Leishmania major | trypanothione reductase | 0.0665 | 0.3034 | 1 |
Plasmodium falciparum | glutathione reductase | 0.023 | 0.0963 | 0.2803 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0061 | 0.0156 | 0.1305 |
Echinococcus multilocularis | smad | 0.0067 | 0.0185 | 0.0589 |
Trypanosoma cruzi | 2,4-dienoyl-coa reductase-like protein, putative | 0.0061 | 0.0156 | 0.0411 |
Trichomonas vaginalis | apoptosis inducing factor, putative | 0.0061 | 0.0156 | 0.1305 |
Plasmodium falciparum | thioredoxin reductase | 0.0665 | 0.3034 | 1 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0169 | 0.0672 | 0.1462 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0107 | 0.0374 | 0.3607 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0033 | 0.0028 |
Echinococcus granulosus | tar DNA binding protein | 0.0649 | 0.2958 | 0.9662 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0033 | 0.0061 |
Toxoplasma gondii | ABC1 family protein | 0.0035 | 0.0033 | 0.0092 |
Brugia malayi | NADPH:adrenodoxin oxidoreductase, mitochondrial precursor | 0.0061 | 0.0156 | 0.0332 |
Echinococcus granulosus | apoptosis inducing factor 1 mitochondrial | 0.0061 | 0.0156 | 0.0511 |
Mycobacterium ulcerans | NADH dehydrogenase | 0.0061 | 0.0156 | 0.1326 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0035 | 0.0033 | 0.0091 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0134 | 0.0505 | 0.4993 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.0033 | 0.0092 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.023 | 0.0963 | 0.3163 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0045 | 0.008 | 0.0491 |
Mycobacterium ulcerans | glutamate synthase subunit beta | 0.0061 | 0.0156 | 0.1326 |
Loa Loa (eye worm) | programmed cell death 8 | 0.0061 | 0.0156 | 0.0332 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprA | 0.0061 | 0.0156 | 0.1326 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.0064 | 0.0168 | 0.0448 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0107 | 0.0374 | 0.1137 |
Schistosoma mansoni | Smad4 | 0.0067 | 0.0185 | 0.018 |
Schistosoma mansoni | hypothetical protein | 0.0061 | 0.0156 | 0.0151 |
Leishmania major | hypothetical protein, conserved | 0.0061 | 0.0156 | 0.0411 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0073 | 0.021 | 0.1877 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0134 | 0.0505 | 0.1572 |
Onchocerca volvulus | 0.0061 | 0.0156 | 0.1555 | |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0061 | 0.0156 | 0.0511 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0107 | 0.0374 | 0.1137 |
Onchocerca volvulus | Mothers against decapentaplegic homolog | 0.003 | 0.0008 | 0.003 |
Leishmania major | 2,4-dienoyl-coa reductase fadh1, putative | 0.0061 | 0.0156 | 0.0411 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0134 | 0.0505 | 0.1096 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.023 | 0.0963 | 0.1182 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.023 | 0.0963 | 0.3099 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0061 | 0.0156 | 0.0495 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.008 | 0.0247 | 0.2267 |
Loa Loa (eye worm) | pyridine nucleotide-disufhide oxidoreductase | 0.0061 | 0.0156 | 0.0332 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.023 | 0.0963 | 0.3099 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.1686 | 0.7902 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.0234 | 0.0978 | 1 |
Echinococcus granulosus | sulfide:quinone oxidoreductase | 0.0061 | 0.0156 | 0.0511 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0079 | 0.0243 | 0.2227 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0072 | 0.021 | 0.1871 |
Schistosoma mansoni | tar DNA-binding protein | 0.0649 | 0.2958 | 0.2954 |
Leishmania major | NADH dehydrogenase, putative | 0.0061 | 0.0156 | 0.0411 |
Trypanosoma brucei | 2,4-dienoyl-coa reductase-like protein | 0.0061 | 0.0156 | 0.0411 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0045 | 0.008 | 0.0491 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.0212 | 0.1585 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0033 | 0.0062 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0665 | 0.3034 | 0.6642 |
Brugia malayi | MH1 domain containing protein | 0.0037 | 0.0042 | 0.0081 |
Echinococcus multilocularis | tumor protein p63 | 0.0331 | 0.1443 | 0.4706 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0134 | 0.0505 | 0.1572 |
Trichomonas vaginalis | dihydrolipoamide dehydrogenase, putative | 0.0061 | 0.0156 | 0.1305 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0033 | 0.0061 |
Echinococcus granulosus | mothers against decapentaplegic 2 | 0.003 | 0.0008 | 0.0026 |
Brugia malayi | glutamate synthase | 0.0061 | 0.0156 | 0.0332 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0096 | 0.0199 |
Trypanosoma cruzi | NADH dehydrogenase, putative | 0.0061 | 0.0156 | 0.0411 |
Mycobacterium ulcerans | NADPH dependent 2,4-dienoyl-CoA reductase FadH | 0.0061 | 0.0156 | 0.1326 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0134 | 0.0505 | 0.1649 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0134 | 0.0505 | 0.1572 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.023 | 0.0963 | 1 |
Schistosoma mansoni | smad1 5 8 and | 0.0067 | 0.0185 | 0.018 |
Schistosoma mansoni | sulfide quinone reductase | 0.0061 | 0.0156 | 0.0151 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.023 | 0.0963 | 0.2101 |
Trypanosoma cruzi | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0061 | 0.0156 | 0.0411 |
Trypanosoma cruzi | NADH dehydrogenase, putative | 0.0061 | 0.0156 | 0.0411 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0073 | 0.021 | 0.1877 |
Schistosoma mansoni | tar DNA-binding protein | 0.0649 | 0.2958 | 0.2954 |
Leishmania major | 2,4-dienoyl-coa reductase-like protein | 0.0061 | 0.0156 | 0.0411 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0033 | 0.0028 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.0212 | 0.1585 |
Loa Loa (eye worm) | beta-lactamase | 0.0035 | 0.0033 | 0.0061 |
Brugia malayi | glutathione reductase | 0.0665 | 0.3034 | 0.6642 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.023 | 0.0963 | 0.3099 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.023 | 0.0963 | 0.3099 |
Trypanosoma cruzi | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0061 | 0.0156 | 0.0411 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0134 | 0.0505 | 0.4993 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0061 | 0.0156 | 0.0495 |
Plasmodium falciparum | glutathione reductase | 0.0665 | 0.3034 | 1 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0671 | 0.3062 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0156 | 0.0332 |
Mycobacterium leprae | PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) | 0.0061 | 0.0156 | 0.0157 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0061 | 0.0156 | 0.1305 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0045 | 0.008 | 0.0163 |
Mycobacterium ulcerans | thioredoxin reductase TrxB2 | 0.0061 | 0.0156 | 0.1326 |
Brugia malayi | Pre-SET motif family protein | 0.0205 | 0.0843 | 0.1837 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0079 | 0.0243 | 0.2227 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0073 | 0.0212 | 0.0207 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.01 | 0.0341 | 0.3257 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.023 | 0.0963 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0061 | 0.0156 | 0.0411 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0169 | 0.0672 | 0.1462 |
Trichomonas vaginalis | glutathione reductase, putative | 0.023 | 0.0963 | 0.9845 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0134 | 0.0505 | 0.1096 |
Mycobacterium tuberculosis | Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) | 0.0061 | 0.0156 | 0.0157 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.023 | 0.0963 | 1 |
Mycobacterium tuberculosis | Probable reductase | 0.1517 | 0.7095 | 0.8975 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0035 | 0.0033 | 0.0108 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0067 | 0.0185 | 0.0589 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0061 | 0.0156 | 0.1305 |
Mycobacterium ulcerans | NADH dehydrogenase Ndh1 | 0.0061 | 0.0156 | 0.1326 |
Mycobacterium leprae | Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) | 0.0061 | 0.0156 | 0.0157 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.023 | 0.0963 | 0.3099 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0107 | 0.0374 | 0.3607 |
Toxoplasma gondii | thioredoxin reductase | 0.0665 | 0.3034 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0008 | 0.0006 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.0212 | 0.1585 |
Echinococcus multilocularis | apoptosis inducing factor 1 mitochondrial | 0.0061 | 0.0156 | 0.0495 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.1517 | 0.7095 | 0.8975 |
Mycobacterium tuberculosis | Probable thioredoxin reductase TrxB2 (TRXR) (TR) | 0.0061 | 0.0156 | 0.0157 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.003 | 0.0008 | 0.0006 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.1517 | 0.7095 | 0.8975 |
Mycobacterium ulcerans | monoxygenase | 0.0061 | 0.0156 | 0.1326 |
Echinococcus multilocularis | sulfide:quinone oxidoreductase | 0.0061 | 0.0156 | 0.0495 |
Leishmania major | hypothetical protein, conserved | 0.0061 | 0.0156 | 0.0411 |
Treponema pallidum | NADH oxidase | 0.023 | 0.0963 | 1 |
Brugia malayi | TAR-binding protein | 0.0649 | 0.2958 | 0.6475 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0067 | 0.0185 | 0.0589 |
Trypanosoma brucei | trypanothione reductase | 0.0665 | 0.3034 | 1 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0073 | 0.0212 | 0.0691 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.023 | 0.0963 | 0.3135 |
Mycobacterium ulcerans | ferredoxin reductase | 0.0061 | 0.0156 | 0.1326 |
Trypanosoma brucei | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0061 | 0.0156 | 0.0411 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0134 | 0.0505 | 0.1572 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0067 | 0.0185 | 0.018 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0061 | 0.0156 | 0.0411 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0061 | 0.0156 | 0.0511 |
Brugia malayi | Thioredoxin reductase | 0.0665 | 0.3034 | 0.6642 |
Brugia malayi | RNA binding protein | 0.0649 | 0.2958 | 0.6475 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0112 | 0.0233 |
Brugia malayi | mothers against decapentaplegic homolog 3 | 0.003 | 0.0008 | 0.0006 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.023 | 0.0963 | 0.3146 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.01 | 0.0341 | 0.3257 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0671 | 0.3062 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0042 | 0.0081 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0986 | 0.4566 | 1 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.0045 | 0.008 | 0.026 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0986 | 0.4566 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.1517 | 0.7095 | 0.8975 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0665 | 0.3034 | 0.3814 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.023 | 0.0963 | 0.0959 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.1686 | 0.7902 | 1 |
Trypanosoma brucei | NADH dehydrogenase | 0.0061 | 0.0156 | 0.0411 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.023 | 0.0963 | 0.3099 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.1517 | 0.7095 | 0.8975 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.023 | 0.0963 | 0.3163 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.01 | 0.0341 | 0.3257 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0649 | 0.2958 | 0.6475 |
Schistosoma mansoni | Smad4 | 0.003 | 0.0008 | 0.0003 |
Trypanosoma cruzi | 2,4-dienoyl-coa reductase fadh1, putative | 0.0061 | 0.0156 | 0.0411 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.023 | 0.0963 | 0.3099 |
Brugia malayi | MH1 domain containing protein | 0.0067 | 0.0185 | 0.0395 |
Loa Loa (eye worm) | TAR-binding protein | 0.0649 | 0.2958 | 0.6475 |
Brugia malayi | Smad1 | 0.0067 | 0.0185 | 0.0395 |
Plasmodium vivax | ferrodoxin reductase, putative | 0.0061 | 0.0156 | 0.0499 |
Toxoplasma gondii | NADH dehydrogenase (NDH2-II) | 0.0061 | 0.0156 | 0.0499 |
Mycobacterium tuberculosis | Possible dehydrogenase/reductase | 0.0061 | 0.0156 | 0.0157 |
Brugia malayi | MH2 domain containing protein | 0.0986 | 0.4566 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0033 | 0.0061 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0045 | 0.008 | 0.0491 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.0033 | 0.0062 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0061 | 0.0156 | 0.0499 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0665 | 0.3034 | 1 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0107 | 0.0374 | 0.1137 |
Schistosoma mansoni | glutamate synthase | 0.0061 | 0.0156 | 0.0151 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.023 | 0.0963 | 0.3163 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.023 | 0.0963 | 0.3099 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.023 | 0.0963 | 1 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0035 | 0.0033 | 0.0061 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0045 | 0.008 | 0.0491 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.023 | 0.0963 | 0.3163 |
Trichomonas vaginalis | dihydropyrimidine dehydrogenase, putative | 0.0061 | 0.0156 | 0.1305 |
Onchocerca volvulus | 0.0035 | 0.0033 | 0.0287 | |
Mycobacterium leprae | THIOREDOXIN TRXC (TRX) (MPT46) | 0.0061 | 0.0156 | 0.0157 |
Echinococcus granulosus | mothers against decapentaplegic 6 | 0.003 | 0.0008 | 0.0026 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0649 | 0.2958 | 0.6475 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0134 | 0.0505 | 0.1572 |
Loa Loa (eye worm) | Smad1 | 0.0067 | 0.0185 | 0.0395 |
Trypanosoma brucei | phosphatidylinositol 3-related kinase, putative | 0.0045 | 0.008 | 0.0155 |
Schistosoma mansoni | hypothetical protein | 0.0073 | 0.0212 | 0.0207 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0073 | 0.021 | 0.1877 |
Mycobacterium tuberculosis | Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate | 0.0061 | 0.0156 | 0.0157 |
Schistosoma mansoni | Smad4 | 0.003 | 0.0008 | 0.0003 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0225 | 0.0939 | 0.1152 |
Mycobacterium leprae | Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate | 0.0061 | 0.0156 | 0.0157 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.023 | 0.0963 | 0.3099 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0045 | 0.008 | 0.0155 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0073 | 0.0212 | 0.0676 |
Trypanosoma brucei | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0061 | 0.0156 | 0.0411 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0061 | 0.0156 | 0.0499 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0045 | 0.008 | 0.0491 |
Leishmania major | phosphatidylinositol 3-related kinase, putative | 0.0045 | 0.008 | 0.0155 |
Loa Loa (eye worm) | RNA binding protein | 0.0649 | 0.2958 | 0.6475 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0061 | 0.0156 | 0.1305 |
Echinococcus granulosus | Smad4 | 0.0067 | 0.0185 | 0.0605 |
Onchocerca volvulus | 0.0035 | 0.0033 | 0.0287 | |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.1517 | 0.7095 | 0.8975 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.008 | 0.0247 | 0.2267 |
Schistosoma mansoni | smad1 5 8 and | 0.0067 | 0.0185 | 0.018 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0045 | 0.008 | 0.0155 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.023 | 0.0963 | 1 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0067 | 0.0185 | 0.0605 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0036 | 0.0037 | 0.0037 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0134 | 0.0505 | 0.05 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0134 | 0.0505 | 0.1635 |
Brugia malayi | MH1 domain containing protein | 0.0037 | 0.0042 | 0.0081 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0107 | 0.0374 | 0.3607 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0205 | 0.0843 | 0.1837 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.0134 | 0.0505 | 1 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.0045 | 0.008 | 0.0155 |
Echinococcus granulosus | pyridine nucleotide disulfide oxidoreductase | 0.0061 | 0.0156 | 0.0511 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0048 | 0.0096 | 0.0091 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0665 | 0.3034 | 1 |
Schistosoma mansoni | disulfide oxidoreductase | 0.0061 | 0.0156 | 0.0151 |
Brugia malayi | MH2 domain containing protein | 0.0067 | 0.0185 | 0.0395 |
Loa Loa (eye worm) | glutathione reductase | 0.0665 | 0.3034 | 0.6642 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.023 | 0.0963 | 0.2803 |
Trypanosoma brucei | NADPH:adrenodoxin oxidoreductase, mitochondrial, putative | 0.0061 | 0.0156 | 0.0411 |
Echinococcus multilocularis | glutamate synthase | 0.0061 | 0.0156 | 0.0495 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.023 | 0.0963 | 0.2803 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0033 | 0.0061 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.023 | 0.0963 | 0.3099 |
Onchocerca volvulus | 0.0035 | 0.0033 | 0.0287 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0134 | 0.0505 | 0.4993 |
Echinococcus granulosus | tumor protein p63 | 0.0331 | 0.1443 | 0.4715 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.0112 | 0.0233 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.023 | 0.0963 | 0.3099 |
Plasmodium falciparum | thioredoxin reductase | 0.023 | 0.0963 | 0.2803 |
Leishmania major | phosphatidylinositol 3-kinase, putative | 0.0045 | 0.008 | 0.0155 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0134 | 0.0505 | 0.1572 |
Brugia malayi | MH2 domain containing protein | 0.003 | 0.0008 | 0.0006 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0061 | 0.0156 | 0.1305 |
Trichomonas vaginalis | glutamate synthase, putative | 0.0061 | 0.0156 | 0.1305 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.1686 | 0.7902 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0061 | 0.0156 | 0.1326 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0087 | 0.028 | 0.2617 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0061 | 0.0156 | 0.0499 |
Onchocerca volvulus | 0.0234 | 0.0978 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0033 | 0.0061 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.0045 | 0.008 | 0.0074 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.0212 | 0.1585 |
Schistosoma mansoni | tar DNA-binding protein | 0.0649 | 0.2958 | 0.2954 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0033 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0033 | 0.0061 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprA | 0.0061 | 0.0156 | 0.1326 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.01 | 0.0341 | 0.3257 |
Brugia malayi | MH2 domain containing protein | 0.0067 | 0.0185 | 0.0395 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.003 | 0.0008 | 0.0006 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0029 | 0.0005 | 0.0017 |
Echinococcus multilocularis | mothers against decapentaplegic 6 | 0.003 | 0.0008 | 0.0009 |
Schistosoma mansoni | tar DNA-binding protein | 0.0649 | 0.2958 | 0.2954 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.01 | 0.0341 | 0.3257 |
Mycobacterium tuberculosis | NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) | 0.0061 | 0.0156 | 0.0157 |
Schistosoma mansoni | smad | 0.0067 | 0.0185 | 0.018 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0035 | 0.0033 | 0.0061 |
Brugia malayi | hypothetical protein | 0.0073 | 0.0212 | 0.0453 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.