Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.005 | 0.0325 | 0.2104 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0204 | 0.1902 | 0.622 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.002 | 0.0016 | 0.0006 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0016 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0304 | 0.0955 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.002 | 0.0016 | 0.0006 |
Brugia malayi | AMP-binding enzyme family protein | 0.005 | 0.0325 | 0.1025 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0035 | 0.0172 | 0.0574 |
Brugia malayi | AMP-binding enzyme family protein | 0.005 | 0.0325 | 0.1025 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0241 | 0.2283 | 0.7474 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0016 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0192 | 0.0586 |
Echinococcus granulosus | dna polymerase eta | 0.002 | 0.0016 | 0.0002 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.002 | 0.0016 | 0.0017 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0016 | 0.0054 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0016 | 0.0054 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0048 | 0.0304 | 0.029 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.005 | 0.0325 | 0.2104 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0345 | 0.0479 |
Brugia malayi | hypothetical protein | 0.0077 | 0.0597 | 0.1919 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0094 | 0.078 | 0.0766 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0056 | 0.1448 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0836 | 0.8378 | 0.8376 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0044 | 0.0265 | 0.863 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0037 | 0.0192 | 0.0798 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.1303 | 0.4246 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.005 | 0.0325 | 0.2104 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0044 | 0.0265 | 0.0882 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0016 | 0.0054 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0044 | 0.0261 | 0.0824 |
Schistosoma mansoni | DNA polymerase eta | 0.002 | 0.0016 | 0.0002 |
Entamoeba histolytica | hypothetical protein | 0.0077 | 0.0597 | 0.6162 |
Schistosoma mansoni | hypothetical protein | 0.0077 | 0.0597 | 0.0844 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0016 | 0.0054 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0044 | 0.0265 | 0.0251 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0026 | 0.0074 | 0.006 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0147 | 0.1322 | 0.4403 |
Brugia malayi | intermediate filament protein | 0.0053 | 0.0356 | 0.1124 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.0287 | 0.0394 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0028 | 0.0103 | 0.0293 |
Schistosoma mansoni | tar DNA-binding protein | 0.0316 | 0.305 | 0.4398 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0172 | 0.5435 |
Loa Loa (eye worm) | RNA binding protein | 0.0316 | 0.305 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0082 | 0.2346 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0029 | 0.0106 | 0.3153 |
Entamoeba histolytica | hypothetical protein | 0.0077 | 0.0597 | 0.6162 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0048 | 0.0304 | 1 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.0016 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0064 | 0.0165 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0052 | 0.0345 | 0.1089 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0356 | 0.1124 |
Onchocerca volvulus | 0.0053 | 0.0356 | 0.1471 | |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0053 | 0.0359 | 0.1152 |
Giardia lamblia | DINP protein human, muc B family | 0.002 | 0.0016 | 0.0066 |
Echinococcus granulosus | intermediate filament protein | 0.0053 | 0.0356 | 0.0342 |
Schistosoma mansoni | hypothetical protein | 0.0204 | 0.1902 | 0.2735 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.005 | 0.0325 | 0.1396 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.002 | 0.0016 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0192 | 0.0586 |
Trypanosoma brucei | phosphatidylinositol 3-kinase tor, putative | 0.0021 | 0.0026 | 0.0087 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0037 | 0.0192 | 0.0798 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0056 | 0.1435 |
Giardia lamblia | GTOR | 0.0044 | 0.0265 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0056 | 0.1448 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0112 | 0.096 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0324 | 0.102 |
Echinococcus granulosus | tar DNA binding protein | 0.0316 | 0.305 | 0.304 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0035 | 0.0175 | 0.0719 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0016 | 0.0054 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0056 | 0.1435 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.005 | 0.0324 | 1 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0044 | 0.0265 | 0.0838 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0345 | 0.0479 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.005 | 0.0324 | 1 |
Onchocerca volvulus | 0.0146 | 0.1303 | 1 | |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0056 | 0.1435 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0037 | 0.0196 | 0.5851 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0035 | 0.0175 | 0.0719 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.005 | 0.0324 | 0.9923 |
Echinococcus multilocularis | lamin | 0.0053 | 0.0356 | 0.0342 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0134 | 0.1182 | 0.1169 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0192 | 0.0258 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0077 | 0.0597 | 0.0844 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0094 | 0.078 | 0.2521 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0244 | 0.231 | 0.2299 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.005 | 0.0325 | 0.2104 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.0192 | 0.0178 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.016 | 0.1452 | 0.144 |
Leishmania major | DNA polymerase eta, putative | 0.002 | 0.0016 | 0.0006 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0192 | 0.0595 |
Schistosoma mansoni | hypothetical protein | 0.0094 | 0.078 | 0.1109 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0022 | 0.0042 | 0.0027 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.002 | 0.0016 | 0.0005 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.002 | 0.0016 | 0.0002 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0035 | 0.0175 | 0.0719 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.0192 | 0.0586 |
Mycobacterium ulcerans | lipase LipD | 0.0037 | 0.0192 | 0.1203 |
Brugia malayi | RNA binding protein | 0.0316 | 0.305 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0094 | 0.078 | 0.2521 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0147 | 0.1322 | 0.4376 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0048 | 0.0304 | 0.0955 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.0287 | 0.0394 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0192 | 0.0586 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.002 | 0.0014 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0016 | 0.0054 |
Echinococcus granulosus | dna polymerase kappa | 0.002 | 0.0016 | 0.0002 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.005 | 0.0325 | 0.2104 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0124 | 0.108 | 0.1067 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.016 | 0.1452 | 0.144 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0693 | 0.6916 | 0.6912 |
Leishmania major | DNA polymerase kappa, putative | 0.002 | 0.0016 | 0.0006 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0037 | 0.0196 | 0.1226 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.002 | 0.0014 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0316 | 0.305 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0316 | 0.305 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0056 | 0.1448 |
Schistosoma mansoni | hypothetical protein | 0.0094 | 0.078 | 0.1109 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.005 | 0.0325 | 0.2104 |
Schistosoma mansoni | tar DNA-binding protein | 0.0316 | 0.305 | 0.4398 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0037 | 0.0192 | 0.0798 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0415 | 0.132 |
Brugia malayi | TAR-binding protein | 0.0316 | 0.305 | 1 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0693 | 0.6916 | 0.6912 |
Brugia malayi | hypothetical protein | 0.0244 | 0.231 | 0.7562 |
Echinococcus multilocularis | protein dispatched 1 | 0.0055 | 0.0374 | 0.036 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0192 | 0.6133 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.008 | 0.2254 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0311 | 0.3002 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0164 | 0.1492 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0016 | 0.0054 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0035 | 0.0172 | 0.0529 |
Loa Loa (eye worm) | hypothetical protein | 0.0244 | 0.231 | 0.7562 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.005 | 0.0321 | 0.1011 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0298 | 0.287 | 0.9407 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0048 | 0.0304 | 0.029 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0037 | 0.0192 | 0.0798 |
Schistosoma mansoni | hypothetical protein | 0.0094 | 0.078 | 0.1109 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 0.0345 | 0.0331 |
Toxoplasma gondii | target of rapamycin (TOR), putative | 0.0033 | 0.0149 | 0.4301 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.005 | 0.0324 | 0.1036 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.0192 | 0.0586 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0077 | 0.0597 | 0.0583 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0044 | 0.0265 | 0.0838 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.005 | 0.0324 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0016 | 0.0054 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0311 | 0.3002 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0345 | 0.0479 |
Echinococcus multilocularis | GPCR, family 2 | 0.0094 | 0.078 | 0.0766 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0192 | 0.6133 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0192 | 0.6133 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0192 | 0.0586 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0172 | 0.5435 |
Loa Loa (eye worm) | TAR-binding protein | 0.0316 | 0.305 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0316 | 0.305 | 0.304 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0016 | 0.0005 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0077 | 0.0597 | 0.0583 |
Schistosoma mansoni | intermediate filament proteins | 0.0053 | 0.0356 | 0.0494 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0149 | 0.4629 |
Schistosoma mansoni | tar DNA-binding protein | 0.0316 | 0.305 | 0.4398 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0044 | 0.0265 | 0.0824 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0149 | 0.4629 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.005 | 0.0325 | 1 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0016 | 0.0002 |
Loa Loa (eye worm) | intermediate filament protein | 0.0053 | 0.0356 | 0.1124 |
Entamoeba histolytica | hypothetical protein | 0.0077 | 0.0597 | 0.6162 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0149 | 0.4629 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0037 | 0.0196 | 0.5851 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0298 | 0.287 | 0.9407 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0192 | 0.0586 |
Onchocerca volvulus | 0.0053 | 0.0356 | 0.1471 | |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0112 | 0.096 | 0.3114 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.0016 | 0.0011 |
Schistosoma mansoni | hypothetical protein | 0.0124 | 0.108 | 0.1544 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.005 | 0.0324 | 0.1036 |
Onchocerca volvulus | 0.005 | 0.0321 | 0.1163 | |
Echinococcus granulosus | lamin | 0.0053 | 0.0356 | 0.0342 |
Mycobacterium ulcerans | hypothetical protein | 0.005 | 0.0325 | 0.2104 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.0192 | 0.0586 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0112 | 0.096 | 0.0946 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0196 | 0.0597 |
Schistosoma mansoni | tar DNA-binding protein | 0.0316 | 0.305 | 0.4398 |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0042 | 0.0039 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0192 | 0.0798 |
Trichomonas vaginalis | esterase, putative | 0.0037 | 0.0192 | 0.6133 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0037 | 0.0196 | 0.0814 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0237 | 0.2242 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0037 | 0.0192 | 0.6133 |
Toxoplasma gondii | hypothetical protein | 0.005 | 0.0327 | 1 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0044 | 0.0265 | 0.863 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0149 | 0.4629 |
Schistosoma mansoni | thyroid hormone receptor | 0.0134 | 0.1182 | 0.1692 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.005 | 0.0325 | 0.1041 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.002 | 0.0016 | 0.0007 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0298 | 0.287 | 0.9407 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.002 | 0.0016 | 0.0002 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0192 | 0.0798 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0192 | 0.0586 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0026 | 0.0074 | 0.006 |
Echinococcus multilocularis | dna polymerase kappa | 0.002 | 0.0016 | 0.0002 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0014 | 0.0048 |
Entamoeba histolytica | phosphatidylinositol3-kinaseTor2, putative | 0.0044 | 0.0265 | 0.2648 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0053 | 0.0356 | 0.1124 |
Echinococcus multilocularis | expressed conserved protein | 0.0105 | 0.089 | 0.0877 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 0.0345 | 0.0331 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0044 | 0.0265 | 0.863 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0037 | 0.0192 | 0.6133 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0149 | 0.4629 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0022 | 0.0042 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0298 | 0.287 | 0.9407 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.002 | 0.0016 | 0.0057 |
Brugia malayi | hypothetical protein | 0.005 | 0.0324 | 0.102 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.0192 | 0.5699 |
Trypanosoma brucei | unspecified product | 0.002 | 0.0016 | 0.0054 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0053 | 0.0356 | 0.1124 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0147 | 0.1322 | 0.4376 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0094 | 0.078 | 0.2521 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0044 | 0.0265 | 0.0838 |
Echinococcus granulosus | GPCR family 2 | 0.0094 | 0.078 | 0.0766 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.005 | 0.0325 | 0.2104 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0037 | 0.0192 | 0.064 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0146 | 0.1303 | 0.1867 |
Loa Loa (eye worm) | hypothetical protein | 0.0204 | 0.1902 | 0.622 |
Leishmania major | hypothetical protein, conserved | 0.005 | 0.0324 | 0.1036 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.0192 | 0.0595 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0325 | 0.1025 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.078 | 0.2521 |
Echinococcus multilocularis | tumor protein p63 | 0.0994 | 1 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0052 | 0.0345 | 0.1089 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0192 | 0.0586 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.005 | 0.0324 | 0.108 |
Mycobacterium ulcerans | DNA polymerase IV | 0.002 | 0.0016 | 0.0011 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.005 | 0.0325 | 0.1041 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0035 | 0.0175 | 0.0719 |
Echinococcus multilocularis | lamin dm0 | 0.0053 | 0.0356 | 0.0342 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.0192 | 0.5743 |
Entamoeba histolytica | FKBP-rapamycin associated protein (FRAP), putative | 0.0044 | 0.0265 | 0.2648 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0037 | 0.0196 | 0.5 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0044 | 0.0265 | 0.0363 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0044 | 0.0265 | 0.0838 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0016 | 0.0054 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0038 | 0.0198 | 0.6347 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.0192 | 0.0178 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.0287 | 0.0394 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0325 | 0.1025 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0016 | 0.0002 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0016 | 0.0006 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0037 | 0.0192 | 0.0798 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0016 | 0.0006 |
Brugia malayi | MH2 domain containing protein | 0.0241 | 0.2283 | 0.7474 |
Echinococcus multilocularis | musashi | 0.0053 | 0.0356 | 0.0342 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 0.0345 | 0.0331 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0016 | 0.0006 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0114 | 0.0977 | 0.1395 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0192 | 0.0595 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0172 | 0.5435 |
Echinococcus granulosus | lamin dm0 | 0.0053 | 0.0356 | 0.0342 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0016 | 0.0006 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0094 | 0.078 | 0.0766 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0044 | 0.0265 | 0.0824 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0311 | 0.3002 | 1 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0112 | 0.096 | 0.0946 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0044 | 0.0261 | 0.0824 |
Entamoeba histolytica | hypothetical protein | 0.0077 | 0.0597 | 0.6162 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0244 | 0.231 | 0.2299 |
Mycobacterium ulcerans | hypothetical protein | 0.0037 | 0.0192 | 0.1203 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0048 | 0.0304 | 0.029 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0044 | 0.0265 | 0.0882 |
Echinococcus multilocularis | protein patched | 0.0048 | 0.0304 | 0.029 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0037 | 0.0192 | 0.1203 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.005 | 0.0325 | 0.3291 |
Schistosoma mansoni | hypothetical protein | 0.005 | 0.0321 | 0.0445 |
Schistosoma mansoni | lamin | 0.0053 | 0.0356 | 0.0494 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0037 | 0.0192 | 0.1203 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0044 | 0.0261 | 0.0868 |
Schistosoma mansoni | thyroid hormone receptor | 0.0134 | 0.1182 | 0.1692 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0149 | 0.4629 |
Mycobacterium ulcerans | beta-lactamase | 0.0037 | 0.0192 | 0.1203 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.008 | 0.2254 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.002 | 0.0016 | 0.0054 |
Schistosoma mansoni | patched 1 | 0.0048 | 0.0304 | 0.042 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0124 | 0.108 | 0.1067 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0064 | 0.0165 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0164 | 0.1492 | 0.6635 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0056 | 0.1448 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0033 | 0.0149 | 0.4629 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.096 | 0.3114 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.005 | 0.0325 | 0.3291 |
Schistosoma mansoni | survival motor neuron protein | 0.005 | 0.0321 | 0.0445 |
Brugia malayi | beta-lactamase | 0.0037 | 0.0192 | 0.0586 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.005 | 0.0325 | 0.1041 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0035 | 0.0172 | 0.0529 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0241 | 0.2283 | 0.7474 |
Echinococcus granulosus | expressed conserved protein | 0.0105 | 0.089 | 0.0877 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.005 | 0.0325 | 0.1396 |
Brugia malayi | hypothetical protein | 0.0032 | 0.0143 | 0.0422 |
Brugia malayi | AMP-binding enzyme family protein | 0.005 | 0.0325 | 0.1025 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.005 | 0.0325 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0094 | 0.078 | 0.0766 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 0.0345 | 0.0331 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0311 | 0.3002 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0074 | 0.0197 |
Onchocerca volvulus | 0.005 | 0.0325 | 0.1199 | |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.005 | 0.0325 | 0.3291 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0082 | 0.2346 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0196 | 0.0597 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0172 | 0.5435 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0037 | 0.0192 | 0.0798 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0016 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0196 | 0.0597 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0016 | 0.0054 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.002 | 0.0016 | 0.0057 |
Schistosoma mansoni | hypothetical protein | 0.0046 | 0.0287 | 0.0394 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0192 | 0.0586 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0196 | 0.0597 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0044 | 0.0261 | 0.0824 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0325 | 0.1025 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0346 | 0.1091 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0196 | 0.0597 |
Schistosoma mansoni | lamin | 0.0053 | 0.0356 | 0.0494 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.003 | 0.0116 | 0.349 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0026 | 0.0082 | 0.2346 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0192 | 0.0258 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0693 | 0.6916 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0316 | 0.305 | 0.4398 |
Brugia malayi | CHE-14 protein | 0.0048 | 0.0304 | 0.0955 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0044 | 0.0265 | 0.0251 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0035 | 0.0172 | 0.5435 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0037 | 0.0192 | 0.0798 |
Schistosoma mansoni | hypothetical protein | 0.0094 | 0.078 | 0.1109 |
Echinococcus multilocularis | dna polymerase eta | 0.002 | 0.0016 | 0.0002 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0028 | 0.0103 | 0.0293 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.0016 | 0.0005 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0192 | 0.0798 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0094 | 0.078 | 0.0766 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.