Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0251 | 0.0805 |
Echinococcus multilocularis | protein patched | 0.0043 | 0.0354 | 0.0339 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.0433 | 0.1374 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0021 | 0.0065 | 0.1211 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0037 | 0.0272 | 0.0304 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0023 | 0.0093 | 0.0257 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.1062 | 0.2831 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0023 | 0.0063 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0272 | 0.2235 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0043 | 0.0354 | 0.0402 |
Brugia malayi | Importin beta-1 subunit | 0.0028 | 0.0161 | 0.0479 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0135 | 0.1541 | 0.1528 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0048 | 0.0419 | 0.1142 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0035 | 0.0097 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0251 | 0.088 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0143 | 0.1649 | 0.1636 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0041 | 0.0333 | 0.0925 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0047 | 0.0412 | 0.3562 |
Plasmodium falciparum | glutathione reductase | 0.0048 | 0.0426 | 1 |
Schistosoma mansoni | importin beta-1 | 0.0028 | 0.0161 | 0.0439 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0035 | 0.0257 | 1 |
Toxoplasma gondii | thioredoxin reductase | 0.0048 | 0.0426 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0093 | 0.0544 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0021 | 0.0065 | 0.005 |
Loa Loa (eye worm) | glutathione reductase | 0.0048 | 0.0426 | 0.1084 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0098 | 0.1062 | 0.2892 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0125 | 0.1412 | 0.1398 |
Schistosoma mansoni | hypothetical protein | 0.0299 | 0.3672 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0035 | 0.0251 | 0.5746 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0048 | 0.0426 | 0.1084 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0016 | 0.0044 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0232 | 0.0807 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0017 | 0.0016 | 0.0044 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0223 | 0.2692 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0047 | 0.0412 | 0.1145 |
Schistosoma mansoni | zinc finger protein | 0.002 | 0.0056 | 0.0154 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0017 | 0.0016 | 0.0044 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.011 | 0.1229 | 0.8596 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0093 | 0.0263 |
Brugia malayi | hypothetical protein | 0.0037 | 0.0272 | 0.0842 |
Entamoeba histolytica | Ran family GTPase | 0.0021 | 0.0065 | 0.0287 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.023 | 0.2773 | 0.3277 |
Mycobacterium tuberculosis | Probable reductase | 0.011 | 0.1229 | 0.4535 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0035 | 0.0251 | 0.0776 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0123 | 0.1389 | 0.5131 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0047 | 0.0412 | 0.2221 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0023 | 0.0095 | 0.008 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0035 | 0.0251 | 0.028 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0419 | 0.1066 |
Echinococcus granulosus | importin subunit beta 1 | 0.0028 | 0.0161 | 0.0173 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0334 | 0.091 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.01 | 0.1093 | 0.1281 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0251 | 0.088 |
Onchocerca volvulus | 0.0035 | 0.0251 | 0.0207 | |
Leishmania major | mitochondrial DNA polymerase beta | 0.0293 | 0.3598 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0479 | 0.123 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0065 | 0.0163 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.011 | 0.1229 | 0.4535 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0293 | 0.3598 | 1 |
Brugia malayi | RNA binding protein | 0.0251 | 0.3052 | 1 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0251 | 0.0776 |
Schistosoma mansoni | patched 1 | 0.0043 | 0.0354 | 0.0964 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0123 | 0.1389 | 0.5131 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0018 | 0.0035 | 0.0019 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0037 | 0.0272 | 0.0256 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0.0354 | 0.1156 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0031 | 0.0194 | 0.4358 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0251 | 0.0805 |
Echinococcus granulosus | tar DNA binding protein | 0.0251 | 0.3052 | 0.3608 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0048 | 0.0426 | 0.0487 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.04 | 0.0385 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0035 | 0.0257 | 0.588 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0272 | 0.2235 |
Schistosoma mansoni | ran | 0.0021 | 0.0065 | 0.0178 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0048 | 0.0419 | 0.0404 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0047 | 0.0412 | 0.3562 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0047 | 0.0412 | 0.2221 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.04 | 0.1089 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0213 | 0.256 | 0.6945 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0018 | 0.0035 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0257 | 0.062 |
Brugia malayi | TAR-binding protein | 0.0251 | 0.3052 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0035 | 0.0251 | 0.0699 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0031 | 0.0194 | 0.0179 |
Echinococcus multilocularis | zinc finger protein | 0.002 | 0.0056 | 0.0041 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0035 | 0.0251 | 0.0236 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0016 | 0.0044 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0047 | 0.0412 | 0.3562 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.04 | 0.0457 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0018 | 0.0035 | 0.0097 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.04 | 0.1089 |
Plasmodium falciparum | importin beta, putative | 0.0028 | 0.0161 | 0.3547 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0018 | 0.0035 | 0.0023 |
Echinococcus multilocularis | tumor protein p63 | 0.0666 | 0.843 | 0.8427 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0257 | 0.062 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0161 | 0.0357 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0047 | 0.0405 | 0.1282 |
Brugia malayi | Pre-SET motif family protein | 0.0031 | 0.0194 | 0.0588 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0251 | 0.3052 | 1 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0028 | 0.0161 | 0.3547 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0017 | 0.0016 | 0.0044 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0016 | 0.0044 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0065 | 0.0182 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0251 | 0.0685 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0035 | 0.0251 | 0.0805 |
Trichomonas vaginalis | importin beta-1, putative | 0.0023 | 0.0093 | 0.0263 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.023 | 0.2773 | 0.2762 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0035 | 0.0251 | 0.088 |
Onchocerca volvulus | 0.0047 | 0.0412 | 0.0792 | |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0257 | 0.062 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0155 | 0.18 | 0.6665 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0047 | 0.0412 | 0.2221 |
Brugia malayi | PHD-finger family protein | 0.0025 | 0.0127 | 0.0365 |
Toxoplasma gondii | exonuclease III APE | 0.0018 | 0.0035 | 0.047 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0272 | 0.074 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.04 | 0.1013 |
Onchocerca volvulus | 0.0098 | 0.1062 | 0.3158 | |
Trichomonas vaginalis | ap endonuclease, putative | 0.0018 | 0.0035 | 0.0066 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0061 | 0.0585 | 0.057 |
Mycobacterium ulcerans | hypothetical protein | 0.0155 | 0.18 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0047 | 0.0412 | 0.1412 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0143 | 0.1649 | 0.1941 |
Plasmodium vivax | SET domain protein, putative | 0.0031 | 0.0194 | 0.4358 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0047 | 0.0412 | 0.1412 |
Brugia malayi | beta-lactamase family protein | 0.0035 | 0.0251 | 0.0776 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.0433 | 0.1374 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.007 | 0.0191 |
Brugia malayi | AMP-binding enzyme family protein | 0.0047 | 0.0412 | 0.1305 |
Schistosoma mansoni | ran | 0.0021 | 0.0065 | 0.0178 |
Brugia malayi | glutathione reductase | 0.0048 | 0.0426 | 0.135 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.01 | 0.1093 | 0.3549 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0065 | 1 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0048 | 0.0426 | 1 |
Brugia malayi | hypothetical protein | 0.023 | 0.2773 | 0.9082 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0018 | 0.0035 | 0.0108 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0047 | 0.0412 | 0.2221 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0047 | 0.0412 | 0.1145 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0035 | 0.0257 | 0.1351 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0251 | 0.0805 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0018 | 0.0035 | 0.0011 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0037 | 0.0272 | 0.0304 |
Onchocerca volvulus | 0.0035 | 0.0251 | 0.0207 | |
Trypanosoma brucei | trypanothione reductase | 0.0048 | 0.0426 | 0.1183 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0037 | 0.0272 | 0.0256 |
Brugia malayi | RNA, U transporter 1 | 0.008 | 0.083 | 0.2682 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0035 | 0.0251 | 0.0805 |
Echinococcus multilocularis | snurportin 1 | 0.0299 | 0.3672 | 0.3662 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0035 | 0.0251 | 0.088 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0047 | 0.0412 | 0.1145 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0035 | 0.0251 | 0.088 |
Schistosoma mansoni | tar DNA-binding protein | 0.0251 | 0.3052 | 0.8312 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0041 | 0.0333 | 0.0925 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.005 | 0.045 | 0.1249 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0257 | 0.062 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0304 | 0.0749 |
Schistosoma mansoni | tar DNA-binding protein | 0.0251 | 0.3052 | 0.8312 |
Loa Loa (eye worm) | hypothetical protein | 0.023 | 0.2773 | 0.7532 |
Echinococcus multilocularis | tar DNA binding protein | 0.0251 | 0.3052 | 0.3041 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0017 | 0.0016 | 0.0044 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0017 | 0.0016 | 0.0044 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0251 | 0.0605 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0043 | 0.0354 | 0.0339 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0251 | 0.0605 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0299 | 0.3672 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0061 | 0.0585 | 0.0677 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0035 | 0.0251 | 0.088 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0251 | 0.0605 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.011 | 0.1229 | 0.4535 |
Mycobacterium ulcerans | hypothetical protein | 0.0047 | 0.0412 | 0.2221 |
Leishmania major | trypanothione reductase | 0.0048 | 0.0426 | 0.1183 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0048 | 0.0426 | 0.0411 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0017 | 0.0023 | 0.0007 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0018 | 0.0035 | 0.3878 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.0095 | 0.026 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0272 | 0.2235 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0043 | 0.0354 | 0.0887 |
Brugia malayi | AMP-binding enzyme family protein | 0.0047 | 0.0412 | 0.1305 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0412 | 0.1046 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0035 | 0.0251 | 0.0685 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.04 | 0.1265 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0251 | 0.0699 |
Toxoplasma gondii | hypothetical protein | 0.0047 | 0.0411 | 0.9645 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0017 | 0.0016 | 0.0044 |
Onchocerca volvulus | 0.0047 | 0.0405 | 0.0767 | |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0161 | 0.0448 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0021 | 0.0065 | 0.1211 |
Plasmodium vivax | glutathione reductase, putative | 0.0048 | 0.0426 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0047 | 0.0412 | 0.2221 |
Echinococcus multilocularis | protein dispatched 1 | 0.0049 | 0.0433 | 0.0417 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0018 | 0.0035 | 0.0066 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.011 | 0.1229 | 0.4535 |
Mycobacterium tuberculosis | Conserved protein | 0.0035 | 0.0251 | 0.088 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0102 | 0.1113 | 0.3032 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0433 | 0.1103 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0048 | 0.0426 | 0.1532 |
Schistosoma mansoni | hypothetical protein | 0.0125 | 0.1412 | 0.3845 |
Echinococcus granulosus | expressed conserved protein | 0.0094 | 0.1015 | 0.1187 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0035 | 0.0257 | 0.0901 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0028 | 0.0161 | 0.0146 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0232 | 0.0807 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0065 | 0.0182 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0021 | 0.0065 | 0.0059 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0125 | 0.1412 | 0.1659 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0293 | 0.3598 | 1 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0293 | 0.3598 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0048 | 0.0419 | 0.0479 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0041 | 0.0333 | 0.0925 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0334 | 0.091 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0257 | 0.062 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0017 | 0.0016 | 0.0044 |
Onchocerca volvulus | 0.0035 | 0.0251 | 0.0207 | |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0016 | 0.0044 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0035 | 0.047 |
Echinococcus granulosus | zinc finger protein | 0.002 | 0.0056 | 0.0048 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0251 | 0.0605 |
Brugia malayi | CHE-14 protein | 0.0043 | 0.0354 | 0.1114 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0232 | 0.0552 |
Onchocerca volvulus | 0.0243 | 0.2941 | 1 | |
Plasmodium falciparum | acyl-CoA synthetase | 0.0035 | 0.0257 | 0.588 |
Leishmania major | importin beta-1 subunit, putative | 0.0023 | 0.0093 | 0.0257 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0041 | 0.0333 | 0.0925 |
Trichomonas vaginalis | ran, putative | 0.0021 | 0.0065 | 0.017 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0035 | 0.0251 | 0.0699 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0016 | 0.0044 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0047 | 0.0412 | 0.148 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0035 | 0.0095 |
Loa Loa (eye worm) | RNA binding protein | 0.0251 | 0.3052 | 0.8298 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0412 | 0.1046 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.04 | 0.0457 |
Schistosoma mansoni | tar DNA-binding protein | 0.0251 | 0.3052 | 0.8312 |
Loa Loa (eye worm) | beta-lactamase | 0.0035 | 0.0251 | 0.0605 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0139 | 0.1597 | 0.4438 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0017 | 0.0016 | 0.0044 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.073 | 0.192 |
Schistosoma mansoni | ap endonuclease | 0.0018 | 0.0035 | 0.0095 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0018 | 0.0035 | 0.0097 |
Echinococcus granulosus | tumor protein p63 | 0.0666 | 0.843 | 1 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.01 | 0.1093 | 0.1079 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0251 | 0.0699 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0035 | 0.0251 | 0.0605 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0048 | 0.0426 | 0.1183 |
Echinococcus multilocularis | expressed conserved protein | 0.0094 | 0.1015 | 0.1001 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0123 | 0.1389 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.036 | 0.0904 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0251 | 0.0605 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0035 | 0.0251 | 0.132 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0031 | 0.0194 | 0.053 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0251 | 0.3052 | 0.8298 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0018 | 0.0035 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.0433 | 0.1103 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0016 | 0.0044 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0035 | 0.0251 | 0.088 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0035 | 0.0251 | 0.088 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0139 | 0.1597 | 0.4438 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0334 | 0.091 |
Leishmania major | GTP-binding protein, putative | 0.0021 | 0.0065 | 0.0182 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0017 | 0.0016 | 0.0044 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0232 | 0.0632 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0123 | 0.1389 | 0.5131 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0047 | 0.0412 | 0.148 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0047 | 0.0412 | 0.2221 |
Brugia malayi | AMP-binding enzyme family protein | 0.0047 | 0.0412 | 0.1305 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0017 | 0.0023 | 0.0009 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0232 | 0.0713 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0139 | 0.1597 | 0.4438 |
Plasmodium falciparum | thioredoxin reductase | 0.0048 | 0.0426 | 1 |
Schistosoma mansoni | bromodomain containing protein | 0.0064 | 0.0632 | 0.1722 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0017 | 0.0016 | 0.0043 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0232 | 0.0807 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0048 | 0.0419 | 0.1142 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0018 | 0.0035 | 0.0072 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0018 | 0.0035 | 0.047 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0016 | 0.0044 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0033 | 0.0232 | 0.0807 |
Mycobacterium ulcerans | beta-lactamase | 0.0035 | 0.0251 | 0.132 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0354 | 0.0887 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0047 | 0.0412 | 0.2221 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.018 | 0.0195 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.04 | 0.1089 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.04 | 0.0385 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0035 | 0.0251 | 0.088 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.1093 | 0.2917 |
Brugia malayi | Bromodomain containing protein | 0.0039 | 0.0303 | 0.0946 |
Schistosoma mansoni | thyroid hormone receptor | 0.0135 | 0.1541 | 0.4198 |
Trichomonas vaginalis | esterase, putative | 0.0035 | 0.0251 | 0.0805 |
Schistosoma mansoni | tar DNA-binding protein | 0.0251 | 0.3052 | 0.8312 |
Echinococcus granulosus | snurportin 1 | 0.0299 | 0.3672 | 0.4345 |
Schistosoma mansoni | tar DNA-binding protein | 0.0251 | 0.3052 | 0.8312 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0251 | 0.0605 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0018 | 0.0035 | 0.0063 |
Toxoplasma gondii | ABC1 family protein | 0.0035 | 0.0251 | 0.5746 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0065 | 0.1211 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.01 | 0.1093 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0412 | 0.1046 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0043 | 0.0354 | 0.0402 |
Schistosoma mansoni | thyroid hormone receptor | 0.0135 | 0.1541 | 0.4198 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0021 | 0.007 | 0.0107 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0021 | 0.0065 | 0.0094 |
Entamoeba histolytica | hypothetical protein | 0.0037 | 0.0272 | 0.2235 |
Loa Loa (eye worm) | TAR-binding protein | 0.0251 | 0.3052 | 0.8298 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.011 | 0.1229 | 0.4535 |
Schistosoma mansoni | survival motor neuron protein | 0.0047 | 0.0405 | 0.1104 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0018 | 0.0035 | 0.0097 |
Plasmodium vivax | importin-beta 2, putative | 0.0028 | 0.0161 | 0.3547 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0334 | 0.091 |
Brugia malayi | Bromodomain containing protein | 0.0076 | 0.0787 | 0.2539 |
Trichomonas vaginalis | set domain proteins, putative | 0.0243 | 0.2941 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0035 | 0.0251 | 0.132 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0023 | 0.0063 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0031 | 0.0194 | 0.053 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0405 | 0.1104 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0335 | 0.0835 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0017 | 0.0016 | 0.0044 |
Brugia malayi | Thioredoxin reductase | 0.0048 | 0.0426 | 0.135 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0028 | 0.0161 | 0.0448 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.011 | 0.1229 | 0.4535 |
Brugia malayi | beta-lactamase | 0.0035 | 0.0251 | 0.0776 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0023 | 0.0095 | 0.0095 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0037 | 0.0272 | 0.074 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0023 | 0.0093 | 0.0263 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0021 | 0.0065 | 0.0182 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0035 | 0.0251 | 0.132 |
Mycobacterium ulcerans | lipase LipD | 0.0035 | 0.0251 | 0.132 |
Brugia malayi | Pre-SET motif family protein | 0.0213 | 0.256 | 0.8379 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.