Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.2772 | 0.2772 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 1 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0053 | 0.7762 | 0.7762 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.2772 | 0.2772 |
Onchocerca volvulus | 0.0027 | 0.2772 | 0.5 | |
Loa Loa (eye worm) | TAR-binding protein | 0.0064 | 1 | 1 |
Echinococcus multilocularis | musashi | 0.0027 | 0.2772 | 0.2772 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.2772 | 0.2561 |
Loa Loa (eye worm) | RNA binding protein | 0.0064 | 1 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0064 | 1 | 1 |
Echinococcus multilocularis | lamin | 0.0027 | 0.2772 | 0.2772 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.2772 | 0.2561 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 1 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0064 | 1 | 1 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.2772 | 0.2772 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.2772 | 0.2772 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.2674 | 0.2674 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 1 | 1 |
Onchocerca volvulus | 0.0027 | 0.2772 | 0.5 | |
Echinococcus granulosus | lamin | 0.0027 | 0.2772 | 0.2772 |
Echinococcus multilocularis | tar DNA binding protein | 0.0064 | 1 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.2772 | 0.2772 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.2772 | 0.2772 |
Brugia malayi | Cytochrome P450 family protein | 0.0053 | 0.7762 | 0.7697 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0064 | 1 | 1 |
Brugia malayi | TAR-binding protein | 0.0064 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 1 | 1 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.0285 | 0.0285 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.