Detailed information for compound 621410

Basic information

Technical information
  • TDR Targets ID: 621410
  • Name: 3-amino-N-(2-ethylphenyl)-7,7-dimethyl-5-oxo- 6,8-dihydrothieno[5,4-b]quinoline-2-carboxami de
  • MW: 393.502 | Formula: C22H23N3O2S
  • H donors: 2 H acceptors: 3 LogP: 5.01 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCc1ccccc1NC(=O)c1sc2c(c1N)cc1c(n2)CC(CC1=O)(C)C
  • InChi: 1S/C22H23N3O2S/c1-4-12-7-5-6-8-15(12)24-20(27)19-18(23)14-9-13-16(25-21(14)28-19)10-22(2,3)11-17(13)26/h5-9H,4,10-11,23H2,1-3H3,(H,24,27)
  • InChiKey: IKZUMYKFQCPVKI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-amino-N-(2-ethylphenyl)-5-keto-7,7-dimethyl-6,8-dihydrothieno[5,4-b]quinoline-2-carboxamide
  • Oprea1_114234
  • Oprea1_512212
  • STOCK3S-04939
  • ZINC01288043

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus ubiquinol cytochrome c reductase Rieske 0.0027 0.0264 0.0264
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0051 0.0118
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0077 0.0943 0.0943
Toxoplasma gondii exonuclease III APE 0.0018 0.0136 0.1422
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0012 0.0061 0.0061
Brugia malayi ImpB/MucB/SamB family protein 0.001 0.0025 0.0058
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0051 0.0118
Brugia malayi beta-lactamase family protein 0.0073 0.0888 0.2037
Schistosoma mansoni tar DNA-binding protein 0.0327 0.4358 1
Brugia malayi hypothetical protein 0.0077 0.0943 0.2164
Trypanosoma brucei DNA polymerase IV, putative 0.001 0.0025 0.0252
Trypanosoma brucei ubiquinol-cytochrome c reductase, putative 0.0027 0.0264 0.2781
Schistosoma mansoni hypothetical protein 0.0049 0.0562 0.129
Echinococcus multilocularis smad 0.0018 0.0133 0.0133
Loa Loa (eye worm) intermediate filament protein 0.011 0.1396 0.3203
Mycobacterium tuberculosis Probable lipase LipD 0.0073 0.0888 0.1419
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0136 0.1422
Trichomonas vaginalis cyclin D, putative 0.0012 0.0061 0.0249
Schistosoma mansoni tar DNA-binding protein 0.0327 0.4358 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0262 0.0418
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0051 0.0118
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0103 0.1295 0.5428
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0035 0.0366 0.0366
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0077 0.0947 0.2174
Loa Loa (eye worm) hypothetical protein 0.0051 0.0591 0.1356
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0262 0.1095
Onchocerca volvulus 0.0027 0.0262 0.1879
Leishmania major DNA polymerase kappa, putative 0.001 0.0025 0.0252
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0018 0.0133 0.0133
Onchocerca volvulus 0.0073 0.0888 0.6358
Brugia malayi intermediate filament protein 0.011 0.1396 0.3203
Echinococcus multilocularis FTZ F1 alpha 0.0012 0.0051 0.0051
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0183 0.2385 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0012 0.0051 0.0051
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0136 0.1422
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0001 0.0003
Mycobacterium tuberculosis Conserved protein 0.0073 0.0888 0.1419
Echinococcus multilocularis cyclin B3 1 0.0012 0.0061 0.0061
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0051 0.0118
Loa Loa (eye worm) hypothetical protein 0.0012 0.0061 0.0139
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0012 0.0051 0.0118
Trypanosoma brucei mitotic cyclin 6 0.0012 0.0061 0.0628
Loa Loa (eye worm) hypothetical protein 0.0012 0.0051 0.0118
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0262 0.2354
Schistosoma mansoni apoferritin-2 0.0017 0.012 0.0276
Plasmodium vivax ataxin-2 like protein, putative 0.0077 0.0947 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0262 0.276
Brugia malayi Smad1 0.0018 0.0133 0.0304
Schistosoma mansoni transcription factor LCR-F1 0.0077 0.0943 0.2164
Echinococcus granulosus ecdysone induced protein 78C 0.0012 0.0051 0.0051
Echinococcus granulosus lamin 0.011 0.1396 0.1396
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0103 0.1295 0.5428
Trypanosoma cruzi PAB1-binding protein , putative 0.0077 0.0947 1
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0136 0.0312
Plasmodium falciparum ataxin-2 like protein, putative 0.0077 0.0947 1
Brugia malayi cytoplasmic intermediate filament protein 0.0059 0.0698 0.1602
Loa Loa (eye worm) ubiquinol-cytochrome c reductase 0.0027 0.0264 0.0606
Onchocerca volvulus 0.0008 0.0001 0.0009
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0012 0.0051 0.0118
Loa Loa (eye worm) hypothetical protein 0.0027 0.0262 0.0602
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.001 0.0025 0.01
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0136 0.1422
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0077 0.0943 0.0943
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0136 0.1422
Echinococcus multilocularis dna polymerase eta 0.001 0.0025 0.0025
Onchocerca volvulus Bile acid receptor homolog 0.0012 0.0051 0.0368
Loa Loa (eye worm) hypothetical protein 0.0106 0.1339 0.3073
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.0103 0.1295 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0051 0.0051
Entamoeba histolytica cyclin, putative 0.0012 0.0061 0.0249
Echinococcus multilocularis GPCR, family 2 0.0049 0.0562 0.0562
Trypanosoma cruzi PAB1-binding protein , putative 0.0077 0.0947 1
Trichomonas vaginalis cyclin B, putative 0.0012 0.0061 0.0249
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0032 0.0325 0.1358
Brugia malayi RNA recognition motif domain containing protein 0.0327 0.4358 1
Onchocerca volvulus 0.011 0.1396 1
Schistosoma mansoni tar DNA-binding protein 0.0327 0.4358 1
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0103 0.1295 0.5428
Brugia malayi ubiquinol-cytochrome c reductase, iron-sulfur subunit family protein 0.0027 0.0264 0.0606
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.001 0.0025 0.0038
Schistosoma mansoni hypothetical protein 0.0049 0.0562 0.129
Brugia malayi hypothetical protein 0.0219 0.2884 0.6617
Trypanosoma brucei DNA polymerase kappa, putative 0.001 0.0025 0.0252
Loa Loa (eye worm) TAR-binding protein 0.0327 0.4358 1
Entamoeba histolytica cyclin, putative 0.0012 0.0061 0.0249
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0049 0.0562 0.0562
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.0103 0.1295 0.2973
Brugia malayi hypothetical protein 0.0077 0.0947 0.2174
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0012 0.0061 0.0628
Loa Loa (eye worm) hypothetical protein 0.0012 0.0051 0.0118
Brugia malayi MH1 domain containing protein 0.001 0.0025 0.0058
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0041 0.0452 0.1036
Echinococcus multilocularis tar DNA binding protein 0.0327 0.4358 0.4358
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.001 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.001 0.0025 0.0058
Echinococcus granulosus GPCR family 2 0.0049 0.0562 0.0562
Trypanosoma cruzi cyclin, putative 0.0012 0.0061 0.0628
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0041 0.0452 0.0452
Echinococcus granulosus smad 0.0018 0.0133 0.0133
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0089 0.111 1
Brugia malayi latrophilin 2 splice variant baaae 0.0106 0.1339 0.3073
Schistosoma mansoni Smad4 0.0018 0.0133 0.0304
Trypanosoma brucei PAB1-binding protein , putative 0.0077 0.0947 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.0888 0.2037
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0262 0.1095
Trichomonas vaginalis cyclin A, putative 0.0012 0.0061 0.0249
Mycobacterium tuberculosis Probable esterase LipL 0.0073 0.0888 0.1419
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0051 0.0118
Onchocerca volvulus 0.0103 0.1295 0.9279
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0051 0.0118
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0888 0.2037
Echinococcus granulosus cyclin B 0.0012 0.0061 0.0061
Mycobacterium ulcerans esterase/lipase LipP 0.0073 0.0888 0.6849
Trypanosoma brucei DNA polymerase kappa, putative 0.001 0.0025 0.0252
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0183 0.2385 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0041 0.0452 0.0452
Trypanosoma cruzi ubiquinol-cytochrome-C-reductase, putative 0.0027 0.0264 0.2781
Schistosoma mansoni smad1 5 8 and 0.0018 0.0133 0.0304
Entamoeba histolytica deoxycytidyl transferase, putative 0.001 0.0025 0.01
Trypanosoma brucei DNA polymerase kappa, putative 0.001 0.0025 0.0252
Treponema pallidum fructose-bisphosphate aldolase 0.0183 0.2385 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0154 0.0244
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0012 0.0051 0.0118
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0041 0.0452 0.0452
Brugia malayi steroid hormone receptor 0.0012 0.0051 0.0118
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0262 0.2354
Loa Loa (eye worm) cyclin domain-containing protein 0.0012 0.0061 0.0139
Brugia malayi ubiquinol-cytochrome c reductase, iron-sulfur subunit family protein 0.0027 0.0264 0.0606
Echinococcus multilocularis tumor protein p63 0.0741 1 1
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.0888 0.937
Schistosoma mansoni ferritin 0.0017 0.012 0.0276
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0169 0.0268
Schistosoma mansoni smad 0.0018 0.0133 0.0304
Schistosoma mansoni ferritin light chain 0.0017 0.012 0.0276
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.0325 0.3424
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0136 0.0564
Loa Loa (eye worm) hypothetical protein 0.002 0.0169 0.0388
Mycobacterium tuberculosis Conserved protein 0.0073 0.0888 0.1419
Echinococcus granulosus ubiquinol cytochrome c oxidoreductase subunit 6 0.0027 0.0264 0.0264
Loa Loa (eye worm) hypothetical protein 0.0012 0.0051 0.0118
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0183 0.2385 1
Trichomonas vaginalis cyclin B, putative 0.0012 0.0061 0.0249
Trypanosoma brucei unspecified product 0.001 0.0025 0.0252
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0888 0.3718
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0073 0.0888 0.6849
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0136 0.0136
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0051 0.0118
Loa Loa (eye worm) transcription factor SMAD2 0.0258 0.3414 0.7833
Onchocerca volvulus Protein ultraspiracle homolog 0.0012 0.0051 0.0368
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0089 0.111 0.1775
Brugia malayi Intermediate filament tail domain containing protein 0.011 0.1396 0.3203
Echinococcus granulosus cyclins 0.0012 0.0061 0.0061
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.0103 0.1295 0.5382
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0466 0.6249 1
Trypanosoma brucei rieske iron-sulfur protein, mitochondrial precursor 0.0027 0.0264 0.2776
Entamoeba histolytica hypothetical protein 0.0077 0.0943 0.3951
Mycobacterium ulcerans DNA polymerase IV 0.001 0.0025 0.0184
Leishmania major cyclin 0.0012 0.0061 0.0628
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.0051 0.0118
Trypanosoma brucei DNA polymerase kappa, putative 0.001 0.0025 0.0252
Giardia lamblia G2/mitotic-specific cyclin B 0.0012 0.0061 0.0151
Trichomonas vaginalis cyclin D, putative 0.0012 0.0061 0.0249
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0103 0.1295 0.5428
Schistosoma mansoni ap endonuclease 0.0018 0.0136 0.0312
Brugia malayi nuclear receptor NHR-88 0.0012 0.0051 0.0118
Echinococcus multilocularis neuropeptide s receptor 0.0232 0.3063 0.3063
Onchocerca volvulus 0.0073 0.0888 0.6358
Brugia malayi Ubiquinol-cytochrome C reductase hinge protein 0.0027 0.0264 0.0607
Brugia malayi photoreceptor-specific nuclear receptor 0.0012 0.0051 0.0118
Brugia malayi Cyclin, N-terminal domain containing protein 0.0012 0.0061 0.0139
Toxoplasma gondii ubiquinol-cytochrome c reductase hinge protein, putative 0.0027 0.0264 0.2781
Schistosoma mansoni apoferritin-2 0.0017 0.012 0.0276
Trypanosoma cruzi CYC2-like cyclin, putative 0.0012 0.0061 0.0628
Loa Loa (eye worm) oxidoreductase 0.0008 0.0001 0.0003
Echinococcus multilocularis cyclins 0.0012 0.0061 0.0061
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0136 0.0068
Entamoeba histolytica cyclin family protein 0.0012 0.0061 0.0249
Leishmania major hypothetical protein, conserved 0.0032 0.0325 0.3424
Brugia malayi MH1 domain containing protein 0.0018 0.0133 0.0304
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0012 0.0051 0.0118
Loa Loa (eye worm) hypothetical protein 0.0027 0.0262 0.0602
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0012 0.0051 0.0118
Loa Loa (eye worm) RNA binding protein 0.0327 0.4358 1
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0103 0.1295 0.5428
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.0051 0.0118
Schistosoma mansoni coup transcription factor 0.0012 0.0051 0.0118
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0041 0.0452 0.1036
Echinococcus multilocularis lamin 0.011 0.1396 0.1396
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0001 0.0003
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0093 0.1159 0.2659
Echinococcus granulosus cyclins 0.0012 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0073 0.0888 0.2037
Loa Loa (eye worm) hypothetical protein 0.0008 0.0001 0.0003
Mycobacterium ulcerans lipase LipD 0.0073 0.0888 0.6849
Toxoplasma gondii LsmAD domain-containing protein 0.0077 0.0947 1
Trichomonas vaginalis cyclin B, putative 0.0012 0.0061 0.0249
Loa Loa (eye worm) MH1 domain-containing protein 0.0018 0.0133 0.0304
Loa Loa (eye worm) filarial common antigen 0.0027 0.0264 0.0607
Toxoplasma gondii ABC1 family protein 0.0073 0.0888 0.937
Loa Loa (eye worm) hypothetical protein 0.0073 0.0888 0.2037
Wolbachia endosymbiont of Brugia malayi Rieske Fe-S protein 0.0027 0.0264 1
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0012 0.0051 0.0368
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0154 0.0244
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0136 0.0564
Trichomonas vaginalis ferritin, putative 0.0017 0.012 0.0499
Echinococcus multilocularis cyclins 0.0012 0.0061 0.0061
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0051 0.0118
Plasmodium falciparum acyl-CoA synthetase 0.002 0.0169 0.1772
Entamoeba histolytica hypothetical protein 0.0077 0.0943 0.3951
Plasmodium vivax ubiquinol cytochrome c oxidoreductase, putative 0.0027 0.0264 0.2776
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0012 0.0051 0.0118
Plasmodium vivax hypothetical protein, conserved 0.0073 0.0888 0.937
Trichomonas vaginalis cyclins, putative 0.0012 0.0061 0.0249
Onchocerca volvulus 0.0008 0.0001 0.0009
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.0103 0.1295 0.2973
Loa Loa (eye worm) hypothetical protein 0.0051 0.0591 0.1356
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0262 0.2017
Schistosoma mansoni lamin 0.011 0.1396 0.3203
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0012 0.0051 0.0118
Brugia malayi MH2 domain containing protein 0.0258 0.3414 0.7833
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0049 0.0562 0.129
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0888 0.3718
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0051 0.0051
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0262 0.276
Loa Loa (eye worm) MH2 domain-containing protein 0.0258 0.3414 0.7833
Schistosoma mansoni tar DNA-binding protein 0.0327 0.4358 1
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0061 0.0249
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0012 0.0051 0.0051
Trypanosoma brucei DNA polymerase kappa, putative 0.001 0.0025 0.0252
Schistosoma mansoni ubiquinol--cytochrome C reductase 0.0027 0.0264 0.0606
Echinococcus granulosus cyclin b3 0.0012 0.0061 0.0061
Echinococcus granulosus nuclear factor of activated T cells 5 0.0108 0.1371 0.1371
Trypanosoma brucei ubiquinol-cytochrome c reductase, putative 0.0027 0.0264 0.2781
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0008 0.0001 0.0003
Loa Loa (eye worm) beta-lactamase 0.0073 0.0888 0.2037
Mycobacterium tuberculosis Probable hydrolase 0.0073 0.0888 0.1419
Loa Loa (eye worm) hypothetical protein 0.0027 0.0262 0.0602
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.001 0.0025 0.0058
Echinococcus multilocularis cyclins 0.0012 0.0061 0.0061
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0136 0.0215
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0103 0.1295 0.5428
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0001 0.0003
Plasmodium falciparum ataxin-2 like protein, putative 0.0077 0.0947 1
Onchocerca volvulus 0.0012 0.0051 0.0368
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0008 0.0001 0.0003
Echinococcus multilocularis ferritin 0.0017 0.012 0.012
Brugia malayi Calcitonin receptor-like protein seb-1 0.0155 0.2009 0.4609
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0012 0.0051 0.0118
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.0051 0.0118
Trypanosoma brucei DNA polymerase kappa, putative 0.001 0.0025 0.0252
Onchocerca volvulus 0.0073 0.0888 0.6358
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.0051 0.0118
Echinococcus multilocularis cyclins 0.0012 0.0061 0.0061
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0017 0.012 0.1073
Trypanosoma brucei DNA polymerase kappa, putative 0.001 0.0025 0.0252
Schistosoma mansoni DNA polymerase eta 0.001 0.0025 0.0058
Loa Loa (eye worm) hypothetical protein 0.0155 0.2009 0.4609
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0041 0.0452 0.1036
Plasmodium falciparum cytochrome b-c1 complex subunit 6, putative 0.0027 0.0264 0.2781
Brugia malayi ecdysteroid receptor 0.0012 0.0051 0.0118
Schistosoma mansoni hypothetical protein 0.0049 0.0562 0.129
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0008 0.0001 0.0001
Schistosoma mansoni cyclin B3 0.0012 0.0061 0.0139
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0262 0.2017
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0888 0.3718
Schistosoma mansoni hypothetical protein 0.0035 0.0366 0.0839
Loa Loa (eye worm) steroid hormone receptor 0.0012 0.0051 0.0118
Echinococcus granulosus dna polymerase kappa 0.001 0.0025 0.0025
Echinococcus granulosus intermediate filament protein 0.011 0.1396 0.1396
Onchocerca volvulus 0.0008 0.0001 0.0009
Brugia malayi MH1 domain containing protein 0.001 0.0025 0.0058
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0051 0.0118
Echinococcus multilocularis neuropeptide receptor A26 0.0232 0.3063 0.3063
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.001 0.0025 0.0058
Trichomonas vaginalis cyclin B3, putative 0.0012 0.0061 0.0249
Onchocerca volvulus 0.0108 0.1372 0.9829
Schistosoma mansoni tar DNA-binding protein 0.0327 0.4358 1
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.002 0.0169 0.5
Trypanosoma brucei DNA polymerase kappa, putative 0.001 0.0025 0.0252
Brugia malayi Cyclin, N-terminal domain containing protein 0.0012 0.0061 0.0139
Echinococcus multilocularis cyclins 0.0012 0.0061 0.0061
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.011 0.1396 0.3203
Echinococcus multilocularis cyclin B 0.0012 0.0061 0.0061
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0008 0.0001 0.0003
Loa Loa (eye worm) latrophilin receptor protein 2 0.0049 0.0562 0.129
Schistosoma mansoni smad1 5 8 and 0.0018 0.0133 0.0304
Onchocerca volvulus 0.0012 0.0061 0.0435
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0012 0.0051 0.0118
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0183 0.2385 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.001 0.0025 0.0252
Echinococcus multilocularis musashi 0.011 0.1396 0.1396
Echinococcus multilocularis mothers against decapentaplegic 5 0.0018 0.0133 0.0133
Echinococcus granulosus cyclins 0.0012 0.0061 0.0061
Brugia malayi TAR-binding protein 0.0327 0.4358 1
Schistosoma mansoni acetyl-CoA synthetase 0.0008 0.0001 0.0003
Loa Loa (eye worm) hypothetical protein 0.0012 0.0051 0.0118
Trypanosoma brucei DNA polymerase IV, putative 0.001 0.0025 0.0252
Mycobacterium leprae conserved hypothetical protein 0.0073 0.0888 0.7992
Trichomonas vaginalis cyclin B, putative 0.0012 0.0061 0.0249
Loa Loa (eye worm) hypothetical protein 0.001 0.0025 0.0058
Trichomonas vaginalis cyclin B, putative 0.0012 0.0061 0.0249
Loa Loa (eye worm) hypothetical protein 0.002 0.0169 0.0388
Brugia malayi Steroid receptor seven-up type 2 0.0012 0.0051 0.0118
Echinococcus multilocularis lamin dm0 0.011 0.1396 0.1396
Loa Loa (eye worm) hypothetical protein 0.0073 0.0888 0.2037
Loa Loa (eye worm) hypothetical protein 0.002 0.0169 0.0388
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0183 0.2385 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0154 0.0244
Schistosoma mansoni hypothetical protein 0.0049 0.0562 0.129
Schistosoma mansoni terminal deoxycytidyl transferase 0.001 0.0025 0.0058
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0012 0.0051 0.0051
Trypanosoma brucei DNA polymerase kappa, putative 0.001 0.0025 0.0252
Loa Loa (eye worm) hypothetical protein 0.0012 0.0051 0.0118
Brugia malayi Latrophilin receptor protein 2 0.0049 0.0562 0.129
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0041 0.0452 0.0452
Loa Loa (eye worm) nuclear factor I 0.001 0.0025 0.0058
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0888 0.937
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0071 0.0863 0.1379
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0136 0.0564
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0012 0.0051 0.0051
Mycobacterium ulcerans hypothetical protein 0.0073 0.0888 0.6849
Leishmania major hypothetical protein, conserved 0.0077 0.0947 1
Trichomonas vaginalis cyclins, putative 0.0012 0.0061 0.0249
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0136 0.1422
Trypanosoma brucei DNA polymerase kappa, putative 0.001 0.0025 0.0252
Trypanosoma cruzi cyclin 6, putative 0.0012 0.0061 0.0628
Echinococcus granulosus expressed protein 0.0017 0.012 0.012
Schistosoma mansoni ferritin light chain 0.0017 0.012 0.0276
Loa Loa (eye worm) hypothetical protein 0.0027 0.0264 0.0606
Trypanosoma cruzi rieske iron-sulfur protein, mitochondrial precursor, putative 0.0027 0.0264 0.2776
Echinococcus multilocularis beta LACTamase domain containing family member 0.0073 0.0888 0.0888
Trypanosoma cruzi cyclin, putative 0.0012 0.0061 0.0628
Leishmania major ubiquinol-cytochrome-c reductase-like protein 0.0027 0.0264 0.2781
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0012 0.0051 0.0118
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0183 0.2385 1
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0262 0.2017
Echinococcus granulosus cyclins 0.0012 0.0061 0.0061
Trypanosoma cruzi DNA polymerase kappa, putative 0.001 0.0025 0.0252
Mycobacterium tuberculosis Probable lipase LipE 0.0073 0.0888 0.1419
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0103 0.1295 0.5428
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0041 0.0452 0.1036
Schistosoma mansoni cyclin B 0.0012 0.0061 0.0139
Trypanosoma cruzi hypothetical protein, conserved 0.0032 0.0325 0.3424
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0041 0.0452 0.1036
Loa Loa (eye worm) hypothetical protein 0.0049 0.0562 0.129
Echinococcus granulosus Smad4 0.0018 0.0133 0.0133
Trichomonas vaginalis esterase, putative 0.0073 0.0888 0.3718
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0888 0.3718
Echinococcus multilocularis cyclins 0.0012 0.0061 0.0061
Brugia malayi MH2 domain containing protein 0.0018 0.0133 0.0304
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0183 0.2385 1
Mycobacterium ulcerans beta-lactamase 0.0073 0.0888 0.6849
Plasmodium vivax ubiquinol-cytochrome c reductase hinge protein, putative 0.0027 0.0264 0.2781
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0155 0.2009 0.4609
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0073 0.0888 0.1419
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0183 0.2385 1
Echinococcus granulosus mothers against decapentaplegic 5 0.0018 0.0133 0.0133
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0012 0.0061 0.0061
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0089 0.111 0.857
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0012 0.0051 0.0118
Onchocerca volvulus 0.0008 0.0001 0.0009
Brugia malayi MH1 domain containing protein 0.0018 0.0133 0.0304
Schistosoma mansoni hypothetical protein 0.0106 0.1339 0.3073
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.0169 0.1772
Echinococcus granulosus cyclin B3 1 0.0012 0.0061 0.0061
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0008 0.0001 0.0001
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0049 0.0562 0.0562
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0017 0.012 0.0191
Loa Loa (eye worm) hypothetical protein 0.0012 0.0051 0.0118
Mycobacterium ulcerans bacterioferritin BfrA 0.0017 0.012 0.092
Toxoplasma gondii hypothetical protein 0.0009 0.002 0.02
Trypanosoma brucei low molecular weight protein tyrosine phosphatase, putative 0.0032 0.0325 0.3424
Trichomonas vaginalis DNA polymerase eta, putative 0.001 0.0025 0.01
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.0051 0.0118
Loa Loa (eye worm) hypothetical protein 0.002 0.0169 0.0388
Echinococcus granulosus neuropeptide s receptor 0.0232 0.3063 0.3063
Trypanosoma cruzi DNA polymerase kappa, putative 0.001 0.0025 0.0252
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0073 0.0888 0.1419
Brugia malayi beta-lactamase family protein 0.0073 0.0888 0.2037
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.0051 0.0118
Echinococcus granulosus dna polymerase eta 0.001 0.0025 0.0025
Plasmodium falciparum cytochrome b-c1 complex subunit Rieske, putative 0.0027 0.0264 0.2776
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0136 0.1039
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0073 0.0888 0.1419
Brugia malayi ImpB/MucB/SamB family protein 0.001 0.0025 0.0058
Echinococcus granulosus neuropeptide receptor A26 0.0232 0.3063 0.3063
Echinococcus multilocularis ubiquinol cytochrome c oxidoreductase subunit 6 0.0027 0.0264 0.0264
Entamoeba histolytica cyclin family protein 0.0012 0.0061 0.0249
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0051 0.0118
Brugia malayi Cyclin, N-terminal domain containing protein 0.0012 0.0061 0.0139
Mycobacterium tuberculosis Conserved hypothetical protein 0.001 0.0025 0.0038
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0262 0.0602
Schistosoma mansoni ferritin 0.0017 0.012 0.0276
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0032 0.0325 0.1358
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0262 0.1095
Loa Loa (eye worm) hypothetical protein 0.0073 0.0888 0.2037
Echinococcus multilocularis dna polymerase kappa 0.001 0.0025 0.0025
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0051 0.0118
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0108 0.1371 0.1371
Trypanosoma cruzi rieske iron-sulfur protein, mitochondrial precursor, putative 0.0027 0.0264 0.2776
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.0051 0.0118
Trypanosoma cruzi DNA polymerase eta, putative 0.001 0.0025 0.0252
Echinococcus multilocularis ecdysone induced protein 78C 0.0012 0.0051 0.0051
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0155 0.2009 0.4609
Trypanosoma cruzi DNA polymerase kappa, putative 0.001 0.0025 0.0252
Echinococcus multilocularis Smad4 0.0018 0.0133 0.0133
Mycobacterium leprae Probable lipase LipE 0.0073 0.0888 0.7992
Mycobacterium ulcerans DNA polymerase IV 0.001 0.0025 0.0184
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0012 0.0051 0.0051
Brugia malayi MH2 domain containing protein 0.0018 0.0133 0.0304
Echinococcus granulosus tar DNA binding protein 0.0327 0.4358 0.4358
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0888 0.3718
Giardia lamblia Hypothetical protein 0.0012 0.0061 0.0151
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0136 0.1422
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.0154 0.0244
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0053 0.0618 0.0618
Echinococcus multilocularis cyclins 0.0012 0.0061 0.0061
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0262 0.0418
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0012 0.0051 0.0051
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0012 0.0051 0.0051
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0183 0.2385 1
Trypanosoma brucei DNA polymerase IV, putative 0.001 0.0025 0.0252
Mycobacterium ulcerans hypothetical protein 0.0027 0.0262 0.2017
Schistosoma mansoni ferritin 0.0017 0.012 0.0276
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0035 0.0366 0.0366
Giardia lamblia Cyclin A 0.0012 0.0061 0.0151
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0888 0.937
Loa Loa (eye worm) hypothetical protein 0.0053 0.0618 0.1419
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0053 0.0618 0.0618
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0051 0.0051
Entamoeba histolytica hypothetical protein 0.0077 0.0943 0.3951
Echinococcus multilocularis cyclin b3 0.0012 0.0061 0.0061
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0327 0.4358 1
Mycobacterium ulcerans bacterioferritin BfrB 0.0017 0.012 0.092
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.001 0.0025 0.0252
Brugia malayi AMP-binding enzyme family protein 0.0008 0.0001 0.0003
Loa Loa (eye worm) MH2 domain-containing protein 0.0018 0.0133 0.0304
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0136 0.0469
Schistosoma mansoni intermediate filament proteins 0.011 0.1396 0.3203
Leishmania major reiske iron-sulfur protein precursor, putative 0.0027 0.0264 0.2776
Echinococcus granulosus lamin dm0 0.011 0.1396 0.1396
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.0051 0.0118
Schistosoma mansoni hypothetical protein 0.0077 0.0943 0.2164
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.0103 0.1295 0.5428
Echinococcus multilocularis ubiquinol cytochrome c reductase, Rieske 0.0027 0.0264 0.0264
Loa Loa (eye worm) hypothetical protein 0.002 0.0169 0.0388
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0008 0.0001 0.0003
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.001 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0108 0.1369 0.314
Loa Loa (eye worm) hypothetical protein 0.0012 0.0061 0.0139
Loa Loa (eye worm) hypothetical protein 0.0012 0.0051 0.0118
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0169 0.1295
Trichomonas vaginalis cyclins, putative 0.0012 0.0061 0.0249
Echinococcus granulosus cyclins 0.0012 0.0061 0.0061
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0012 0.0051 0.0051
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0012 0.0051 0.0118
Echinococcus granulosus beta LACTamase domain containing family member 0.0073 0.0888 0.0888
Brugia malayi beta-lactamase 0.0073 0.0888 0.2037
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0262 0.2017
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0262 0.2017
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0183 0.2385 1
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0012 0.0051 0.0051
Loa Loa (eye worm) Smad1 0.0018 0.0133 0.0304
Leishmania major DNA polymerase eta, putative 0.001 0.0025 0.0252
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0049 0.0562 0.0562
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0059 0.0698 0.1602
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0262 0.276
Onchocerca volvulus 0.011 0.1396 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0051 0.0118
Giardia lamblia Fructose-bisphosphate aldolase 0.0183 0.2385 1
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0262 0.0602
Trichomonas vaginalis cyclins, putative 0.0012 0.0061 0.0249
Echinococcus multilocularis thyroid hormone receptor alpha 0.0012 0.0051 0.0051
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0888 0.2037
Loa Loa (eye worm) hypothetical protein 0.0108 0.1372 0.3149
Schistosoma mansoni cyclins 0.0012 0.0061 0.0139
Schistosoma mansoni smad1 5 8 and 0.0018 0.0133 0.0304
Echinococcus granulosus TGF beta signal transducer SmadC 0.0018 0.0133 0.0133
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0018 0.0133 0.0304
Schistosoma mansoni ap endonuclease 0.0018 0.0136 0.0312
Schistosoma mansoni cellular tumor antigen P53 0.0108 0.1372 0.3149
Loa Loa (eye worm) hypothetical protein 0.0073 0.0888 0.2037
Trypanosoma brucei DNA polymerase eta, putative 0.001 0.0025 0.0252
Loa Loa (eye worm) hypothetical protein 0.0008 0.0001 0.0003
Brugia malayi RNA binding protein 0.0327 0.4358 1
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0262 0.2017
Loa Loa (eye worm) hypothetical protein 0.011 0.1396 0.3203
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0049 0.0562 0.0562
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0012 0.0051 0.0118
Trypanosoma cruzi ubiquinol-cytochrome c reductase, putative 0.0027 0.0264 0.2781
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0017 0.012 0.0191
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0073 0.0888 0.2037
Mycobacterium tuberculosis Conserved protein 0.0073 0.0888 0.1419
Trichomonas vaginalis cyclins, putative 0.0012 0.0061 0.0249
Plasmodium falciparum cyclin 0.0012 0.0061 0.0628
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0262 0.0602
Echinococcus granulosus FTZ F1 alpha 0.0012 0.0051 0.0051
Echinococcus granulosus ferritin 0.0017 0.012 0.012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0012 0.0051 0.0118
Echinococcus multilocularis expressed protein 0.0017 0.012 0.012
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0136 0.0312
Entamoeba histolytica hypothetical protein 0.0077 0.0943 0.3951
Toxoplasma gondii ubiquinol cytochrome c oxidoreductase, putative 0.0027 0.0264 0.2776
Leishmania major hypothetical protein, conserved 0.0073 0.0888 0.937
Schistosoma mansoni hypothetical protein 0.0027 0.0264 0.0607
Schistosoma mansoni lamin 0.011 0.1396 0.3203
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0262 0.2017
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0073 0.0888 0.2037
Brugia malayi nuclear hormone receptor 0.0012 0.0051 0.0118
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0136 0.1078
Brugia malayi hypothetical protein 0.005 0.0574 0.1316
Schistosoma mansoni ferritin 0.0017 0.012 0.0276

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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