Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.5929 | 0.6742 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.5929 | 0.6742 |
Brugia malayi | hypothetical protein | 0.0036 | 0.5929 | 0.5929 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.8794 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.5929 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.5371 | 0.6108 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.8794 | 0.8794 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 1 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.8794 | 0.8794 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.8794 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.5929 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.5371 | 0.5371 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.5929 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.5371 | 0.5371 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.5929 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.8794 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.8794 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.8794 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.8794 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.5929 | 0.6742 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.5929 | 0.6742 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.8794 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.