Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.3114 | 0.2714 |
Trichomonas vaginalis | chromobox protein, putative | 0.0045 | 0.3781 | 0.3419 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.7457 | 0.7457 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0074 | 1 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0074 | 1 | 1 |
Schistosoma mansoni | chromobox protein | 0.0074 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.3114 | 0.3114 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0027 | 0 | 0.5 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.7457 | 0.7457 |
Trichomonas vaginalis | chromobox protein, putative | 0.0045 | 0.3781 | 0.3419 |
Echinococcus granulosus | chromobox protein 1 | 0.0074 | 1 | 1 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.3114 | 0.7399 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.1217 | 0.1217 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0027 | 0 | 0.5 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0027 | 0 | 0.5 |
Echinococcus multilocularis | chromobox protein 1 | 0.0074 | 1 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.7457 | 0.7457 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0045 | 0.3781 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0 | 0.5 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0027 | 0 | 0.5 |
Brugia malayi | chromobox protein homolog 3 | 0.0041 | 0.3114 | 0.3114 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.7457 | 0.7457 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0 | 0.5 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0 | 0.5 |
Echinococcus multilocularis | chromobox protein 1 | 0.0074 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.3114 | 0.2714 |
Schistosoma mansoni | chromobox protein | 0.0074 | 1 | 1 |
Brugia malayi | RNA binding protein | 0.0062 | 0.7457 | 0.7457 |
Echinococcus granulosus | chromobox protein 1 | 0.0074 | 1 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.7457 | 0.7457 |
Trichomonas vaginalis | chromobox protein, putative | 0.0074 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.