Detailed information for compound 622671

Basic information

Technical information
  • TDR Targets ID: 622671
  • Name: N-[4-(2,5-dichlorophenyl)-1,3-thiazol-2-yl]-2 -nitrobenzamide
  • MW: 394.232 | Formula: C16H9Cl2N3O3S
  • H donors: 1 H acceptors: 4 LogP: 4.87 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(c(c1)c1csc(n1)NC(=O)c1ccccc1[N+](=O)[O-])Cl
  • InChi: 1S/C16H9Cl2N3O3S/c17-9-5-6-12(18)11(7-9)13-8-25-16(19-13)20-15(22)10-3-1-2-4-14(10)21(23)24/h1-8H,(H,19,20,22)
  • InChiKey: NWPLLSILWGRECF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[4-(2,5-dichlorophenyl)thiazol-2-yl]-2-nitro-benzamide
  • N-[4-(2,5-dichlorophenyl)-2-thiazolyl]-2-nitrobenzamide
  • N-[4-(2,5-dichlorophenyl)-1,3-thiazol-2-yl]-2-nitro-benzamide
  • ZINC04070501
  • Oprea1_344634

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica hypothetical protein 0.0024 0.2294 0.9806
Echinococcus granulosus L aminoadipate semialdehyde 0.0085 0.9334 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.2332 1
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0009 0.0543 0.019
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0009 0.0543 0.0929
Onchocerca volvulus 0.0024 0.2332 0.2198
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0009 0.0543 1
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0009 0.0543 0.0348
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0009 0.0543 0.0543
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0007 0.0359 0.0546
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.2294 1
Loa Loa (eye worm) hypothetical protein 0.0091 1 1
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.0009 0.0543 0.0929
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0009 0.0543 1
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0009 0.0543 0.0929
Schistosoma mansoni cpg binding protein 0.003 0.2934 0.2934
Echinococcus granulosus cation transporting ATPase 13A3 0.0009 0.0543 0.0228
Schistosoma mansoni type V p-type atpase isoform 0.0009 0.0543 0.0543
Toxoplasma gondii P-type ATPase PMA1 0.0009 0.0543 0.0348
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.2332 1
Trypanosoma cruzi proton motive ATPase 1, putative 0.0009 0.0543 1
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.1626 0.6548
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0009 0.0543 0.5
Trichomonas vaginalis cation-transporting ATPase, putative 0.0009 0.0543 1
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0009 0.0543 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.2751 0.2481
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0009 0.0543 0.0929
Brugia malayi AMP-binding enzyme family protein 0.0024 0.2332 0.2047
Mycobacterium leprae conserved hypothetical protein 0.0024 0.2294 0.9806
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0007 0.0359 0.0025
Brugia malayi E1-E2 ATPase family protein 0.0009 0.0543 0.019
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0009 0.0543 0.0348
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0009 0.0543 0.0929
Onchocerca volvulus 0.0009 0.0543 0.0204
Mycobacterium ulcerans hypothetical protein 0.0024 0.2332 1
Leishmania major P-type H -ATPase, putative 0.0009 0.0543 0.0929
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0007 0.0359 0.0546
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.2294 0.9806
Trichomonas vaginalis antibiotic synthetase, putative 0.0007 0.0359 0.3353
Plasmodium vivax calcium-transporting ATPase, putative 0.0009 0.0543 0.0947
Schistosoma mansoni cpg binding protein 0.003 0.2934 0.2934
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0009 0.0543 0.0929
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0009 0.0543 0.0929
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0009 0.0543 0.0228
Brugia malayi AMP-binding enzyme family protein 0.0024 0.2332 0.2047
Giardia lamblia Phospholipid-transporting ATPase IA, putative 0.0009 0.0543 0.5
Loa Loa (eye worm) hypothetical protein 0.0009 0.0543 0.019
Loa Loa (eye worm) hypothetical protein 0.0009 0.0543 0.019
Echinococcus multilocularis L aminoadipate semialdehyde 0.0085 0.9334 1
Echinococcus granulosus cation transporting atpase worm 0.0009 0.0543 0.0228
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.1512 0.6071
Schistosoma mansoni cation-transporting ATPase 0.0009 0.0543 0.0543
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.2332 1
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.1626 0.6617
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0359 0.0546
Loa Loa (eye worm) hypothetical protein 0.0024 0.2332 0.2047
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.1626 0.6548
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0009 0.0543 1
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0024 0.2294 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.1626 0.1314
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0007 0.0359 0.0546
Trichomonas vaginalis cation-transporting ATPase, putative 0.0009 0.0543 1
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0533 0.018
Trypanosoma brucei P-type H+-ATPase, putative 0.0009 0.0543 0.0947
Trichomonas vaginalis cation-transporting ATPase, putative 0.0009 0.0543 1
Schistosoma mansoni phosphoserine phosphatase 0.0009 0.0543 0.0543
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.6351 0.6351
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.2332 1
Onchocerca volvulus 0.0085 0.9334 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.2332 1
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0009 0.0543 0.0348
Mycobacterium ulcerans cation transporter p-type ATPase D CtpD 0.0009 0.0543 0.0929
Plasmodium vivax P-type ATPase4, putative 0.0009 0.0543 0.0947
Plasmodium vivax copper-transporting ATPase, putative 0.0009 0.0543 0.0947
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.2294 1
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0009 0.0543 0.0947
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0085 0.9334 0.9309
Toxoplasma gondii cation-transporting atpase family protein 0.0009 0.0543 0.0348
Echinococcus granulosus cation transporting ATPase 13A1 0.0009 0.0543 0.0228
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0009 0.0543 0.0228
Loa Loa (eye worm) hypothetical protein 0.0009 0.0543 0.019
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0359 0.0546
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0009 0.0543 0.0947
Schistosoma mansoni copper ABC transporter ATPase 0.0009 0.0543 0.0543
Trypanosoma cruzi P-type H+-ATPase, putative 0.0009 0.0543 1
Schistosoma mansoni cation-transporting atpase worm 0.0009 0.0543 0.0543
Echinococcus multilocularis phosphoserine phosphatase 0.0009 0.0543 0.0228
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0009 0.0543 0.019
Trypanosoma cruzi copper-transporting ATPase, putative 0.0009 0.0543 1
Trichomonas vaginalis cation-transporting ATPase, putative 0.0009 0.0543 1
Mycobacterium leprae PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB 0.0009 0.0543 0.0929
Loa Loa (eye worm) hypothetical protein 0.0018 0.1626 0.1314
Trypanosoma cruzi P-type H+-ATPase, putative 0.0009 0.0543 1
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0009 0.0543 0.0228
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.2332 1
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0007 0.0359 0.0546
Plasmodium falciparum copper-transporting ATPase 0.0009 0.0543 0.0947
Trypanosoma brucei cation-transporting ATPase, putative 0.0009 0.0543 0.0947
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.2294 0.9806
Mycobacterium ulcerans cation-transporter p-type ATPase B CtpB 0.0009 0.0543 0.0929
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0009 0.0543 0.0348
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.2332 1
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0009 0.0543 0.0929
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0009 0.0543 0.0929
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.2332 1
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0009 0.0543 1
Mycobacterium tuberculosis Cation transporter P-type ATPase a CtpA 0.0009 0.0543 0.1424
Schistosoma mansoni cation-transporting atpase worm 0.0009 0.0543 0.0543
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0024 0.2294 0.3675
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.5624 1
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0009 0.0543 0.019
Echinococcus multilocularis cation transporting ATPase 13A1 0.0009 0.0543 0.0228
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0009 0.0543 0.0929
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0009 0.0543 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.2332 1
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0009 0.0543 0.0929
Mycobacterium leprae Probable metal cation-transporting P-type ATPase C CtpC 0.0009 0.0543 0.0929
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0024 0.2294 0.5
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0359 0.0546
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.2294 1
Leishmania major P-type H -ATPase, putative 0.0009 0.0543 0.0929
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0009 0.0543 0.0929
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.2294 0.9817
Loa Loa (eye worm) hypothetical protein 0.0085 0.9334 0.9309
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0009 0.0543 1
Giardia lamblia Copper-transporting P-type ATPase 0.0009 0.0543 0.5
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0007 0.0359 0.0546
Leishmania major calcium-translocating P-type ATPase 0.0009 0.0543 0.0929
Trypanosoma brucei P-type H+-ATPase, putative 0.0009 0.0543 0.0947
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0009 0.0543 0.0228
Schistosoma mansoni atpase class VI type 11c 0.0009 0.0543 0.0543
Echinococcus multilocularis cpg binding protein 0.003 0.2934 0.2886
Trypanosoma cruzi phospholipid-transporting ATPase-like protein, putative 0.0009 0.0543 1
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0009 0.0543 1
Echinococcus multilocularis cation transporting atpase worm 0.0009 0.0543 0.0228
Trichomonas vaginalis cation-transporting ATPase, putative 0.0009 0.0543 1
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.2332 1
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0009 0.0543 0.0228
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0009 0.0543 0.0348
Brugia malayi hypothetical protein 0.0009 0.0543 0.019
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0009 0.0543 0.0228
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0007 0.0337 0.0337
Loa Loa (eye worm) calcium ATPase 0.0009 0.0543 0.019
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0533 0.0218
Schistosoma mansoni acetyl-CoA synthetase 0.0007 0.0359 0.0359
Schistosoma mansoni ATPase 0.0009 0.0543 0.0543
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0085 0.9334 0.9334
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.2332 1
Brugia malayi CXXC zinc finger family protein 0.0028 0.2751 0.2481
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0009 0.0543 0.0929
Loa Loa (eye worm) hypothetical protein 0.0024 0.2332 0.2047
Echinococcus granulosus cpg binding protein 0.003 0.2934 0.2886
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0009 0.0543 0.0929
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0009 0.0543 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.2332 1
Mycobacterium ulcerans metal cation transporter ATPase p-type CtpE 0.0009 0.0543 0.0929
Mycobacterium ulcerans metal cation-transporting p-type ATPase CtpC 0.0009 0.0543 0.0929
Loa Loa (eye worm) hypothetical protein 0.0009 0.0543 0.019
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0009 0.0543 0.0348
Brugia malayi AMP-binding enzyme family protein 0.0024 0.2332 0.2047
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0009 0.0543 0.0947
Loa Loa (eye worm) hypothetical protein 0.0018 0.1626 0.1314
Loa Loa (eye worm) E1-E2 ATPase 0.0009 0.0543 0.019
Mycobacterium ulcerans cation transporter p-type ATPase a CtpA 0.0009 0.0543 0.0929
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.1626 0.6187
Schistosoma mansoni cpg binding protein 0.0028 0.2751 0.2751
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0009 0.0543 1
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0009 0.0543 1
Trypanosoma cruzi cation-transporting ATPase, putative 0.0009 0.0543 1
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.052 0.0167
Loa Loa (eye worm) hypothetical protein 0.0024 0.2332 0.2047
Echinococcus granulosus phospholipid transporting ATPase VA 0.0009 0.0543 0.0228
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.1512 0.6071
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0009 0.0543 1
Loa Loa (eye worm) hypothetical protein 0.0091 1 1
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase CtpV 0.0009 0.0543 0.1424
Plasmodium vivax cation transporting ATPase, putative 0.0009 0.0543 0.0947
Loa Loa (eye worm) hypothetical protein 0.0018 0.1626 0.1314
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0009 0.0543 0.019
Brugia malayi E1-E2 ATPase family protein 0.0009 0.0543 0.019
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0009 0.0543 1
Echinococcus multilocularis cation transporting ATPase 13A3 0.0009 0.0543 0.0228
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.2332 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0533 0.0218
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.2332 1
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0009 0.0543 0.019
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0009 0.0543 1
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0007 0.0359 0.0546
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.1512 0.6071
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0009 0.0543 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.2332 1
Brugia malayi Na,K-ATPase alpha subunit 0.0009 0.0543 0.019
Echinococcus multilocularis phospholipid transporting ATPase VA 0.0009 0.0543 0.0228
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0009 0.0543 0.019
Echinococcus multilocularis phosphoserine phosphatase 0.0009 0.0543 0.0228
Leishmania major proton motive ATPase, putative 0.0009 0.0543 0.0929
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0009 0.0543 0.0947
Trichomonas vaginalis antibiotic synthetase, putative 0.0007 0.0359 0.3353
Echinococcus multilocularis phosphoserine phosphatase 0.0009 0.0543 0.0228
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.1626 0.6421
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.1512 0.6071
Schistosoma mansoni ATPase 0.0009 0.0543 0.0543
Loa Loa (eye worm) hypothetical protein 0.0018 0.1626 0.1314
Mycobacterium tuberculosis Probable cation transporter P-type ATPase D CtpD 0.0009 0.0543 0.1424
Loa Loa (eye worm) hypothetical protein 0.0009 0.0543 0.019
Mycobacterium ulcerans metal cation transporter p-type ATPase, CtpV 0.0009 0.0543 0.0929
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0024 0.2294 0.3675
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0009 0.0543 0.0929
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0024 0.2294 1
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0009 0.0543 0.0348
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0009 0.0543 0.1424
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0009 0.0543 0.0543
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.2294 0.9806
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0007 0.0359 0.0546
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0009 0.0543 0.0929
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0009 0.0543 0.0228
Leishmania major copper-transporting ATPase-like protein, putative 0.0009 0.0543 0.0929
Echinococcus multilocularis copper transporting ATPase 1 0.0009 0.0543 0.0228
Toxoplasma gondii P-type ATPase4, putative 0.0009 0.0543 0.0348
Echinococcus multilocularis phosphoserine phosphatase 0.0009 0.0543 0.0228
Mycobacterium tuberculosis Probable metal cation transporter ATPase P-type CtpE 0.0009 0.0543 0.1424
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0009 0.0543 0.0228
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.2332 1
Echinococcus granulosus copper transporting ATPase 1 0.0009 0.0543 0.0228
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0007 0.0359 0.0546
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.2332 1
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0007 0.0359 0.0025
Onchocerca volvulus 0.0028 0.2751 0.2665
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0009 0.0543 0.0947
Echinococcus multilocularis phosphoserine phosphatase 0.0009 0.0543 0.0228
Schistosoma mansoni eyes absent homolog 0.0091 1 1
Echinococcus multilocularis phosphoserine phosphatase 0.0009 0.0543 0.0228

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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