Detailed information for compound 622913

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 305.331 | Formula: C18H15N3O2
  • H donors: 2 H acceptors: 3 LogP: 2.9 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccc(cc1)/C(=C(\c1nc2c([nH]1)cccc2)/C#N)/O
  • InChi: 1S/C18H15N3O2/c1-2-23-13-9-7-12(8-10-13)17(22)14(11-19)18-20-15-5-3-4-6-16(15)21-18/h3-10,22H,2H2,1H3,(H,20,21)
  • InChiKey: ZPDQKSQAUKCUQW-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus protein C ets 2 0.0012 0.0023 0.0037
Echinococcus multilocularis ATP binding cassette sub family B 0.0022 0.0353 0.0583
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0048 0.1226 0.88
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0048 0.1226 0.88
Schistosoma mansoni hypothetical protein 0.0048 0.1226 0.1226
Echinococcus multilocularis ATP binding cassette sub family B 0.0022 0.0353 0.0583
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0045 0.1122 0.1853
Loa Loa (eye worm) hypothetical protein 0.0034 0.0757 0.0757
Schistosoma mansoni gabp alpha 0.0083 0.2373 0.2373
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0223 0.0223
Loa Loa (eye worm) ABC transporter 0.0022 0.0353 0.0353
Schistosoma mansoni hypothetical protein 0.0018 0.0223 0.0223
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0076 0.2152 1
Schistosoma mansoni ets-related 0.0012 0.0023 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0305 0.0196
Schistosoma mansoni ets-related 0.0252 0.7969 0.7969
Brugia malayi ImpB/MucB/SamB family protein 0.0073 0.2056 0.2056
Plasmodium vivax ABC transporter B family member 3, putative 0.0022 0.0353 0.1325
Trypanosoma cruzi ABC transporter of the mitochondrion, putative 0.0022 0.0353 0.1325
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0111 0.0155
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0045 0.1122 0.1023
Brugia malayi Flap endonuclease-1 0.003 0.0612 0.0612
Trichomonas vaginalis casein kinase II beta chain, putative 0.0076 0.2152 0.2065
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.003 0.0612 0.2574
Mycobacterium tuberculosis Probable transmembrane multidrug efflux pump 0.0045 0.1122 0.7755
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0634 0.2679
Echinococcus multilocularis ets variant gene 4 0.0012 0.0023 0.0037
Schistosoma mansoni ets 0.0012 0.0023 0.0023
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0048 0.1226 0.88
Echinococcus multilocularis ETS transcription factor Elf 2 0.0012 0.0023 0.0037
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.1089 0.4872
Brugia malayi ABC transporter transmembrane region family protein 0.0021 0.0305 0.0305
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0076 0.2152 0.1776
Plasmodium falciparum ABC transporter B family member 4, putative 0.0022 0.0353 0.1641
Trichomonas vaginalis casein kinase II beta chain, putative 0.0076 0.2152 0.2065
Brugia malayi glutaminase DH11.1 0.0313 1 1
Echinococcus multilocularis ETS transcription factor Elf 1 0.0012 0.0023 0.0037
Leishmania major ATP-binding cassette protein subfamily B, member 1, putative 0.0022 0.0353 0.1325
Echinococcus multilocularis ETS transcription factor Elf 5 0.0012 0.0023 0.0037
Schistosoma mansoni blooms syndrome DNA helicase 0.0022 0.0343 0.0343
Trichomonas vaginalis ABC transporter, putative 0.0045 0.1122 0.1023
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0233 0.1081
Plasmodium vivax multidrug resistance-associated protein 2, putative 0.0022 0.0353 0.1325
Plasmodium vivax SET domain protein, putative 0.0034 0.0757 0.3271
Giardia lamblia Multidrug resistance-associated protein 1 0.0057 0.1528 0.7101
Loa Loa (eye worm) D-ets-2 protein 0.0012 0.0023 0.0023
Echinococcus granulosus casein kinase ii subunit beta 0.0076 0.2152 0.3554
Toxoplasma gondii ck2 beta subunit 0.0076 0.2152 1
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0048 0.1226 0.88
Echinococcus multilocularis multidrug resistance protein 1 0.0045 0.1122 0.1853
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0025 0.0441 0.0334
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0305 0.0196
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0022 0.0353 0.1641
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0048 0.1226 0.88
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0019 0.024 0.0778
Plasmodium falciparum ABC transporter B family member 7, putative 0.0022 0.0353 0.1641
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0048 0.1226 0.88
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0045 0.1122 0.1023
Echinococcus multilocularis 0.0048 0.1226 0.2024
Schistosoma mansoni DNA polymerase IV / kappa 0.0014 0.0079 0.0079
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0048 0.1226 0.88
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0048 0.1226 0.1156
Brugia malayi ABC transporter family protein 0.0045 0.1122 0.1122
Trichomonas vaginalis protein kinase ck2-beta, putative 0.0022 0.0363 0.0255
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.1089 0.4872
Echinococcus granulosus ATP binding cassette sub family B 0.0022 0.0353 0.0583
Entamoeba histolytica hypothetical protein 0.0057 0.1528 0.6944
Loa Loa (eye worm) hypothetical protein 0.0057 0.1516 0.1516
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0043 0.1045 0.4857
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0045 0.1122 0.1023
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0048 0.1226 0.1156
Mycobacterium leprae Conserved hypothetical protein 0.0048 0.1226 1
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0044 0.1073 0.1773
Mycobacterium ulcerans component linked with the assembly of cytochrome transport transmembrane ATP-binding protein ABC transporter CydD 0.0022 0.0353 0.0277
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0044 0.1089 0.742
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0048 0.1226 0.1156
Trichomonas vaginalis casein kinase II beta chain, putative 0.0076 0.2152 0.2065
Entamoeba histolytica P-glycoprotein-2, putative 0.0045 0.1122 0.4954
Plasmodium vivax multidrug resistance protein 2, putative 0.0022 0.0353 0.1325
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0022 0.0353 0.0277
Loa Loa (eye worm) hypothetical protein 0.0071 0.1974 0.1974
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0048 0.1226 0.88
Echinococcus granulosus multidrug resistance protein 1 0.0025 0.0441 0.0729
Echinococcus multilocularis multidrug resistance associated protein 7 0.0057 0.1528 0.2524
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0022 0.0353 0.1641
Trichomonas vaginalis casein kinase II beta chain, putative 0.0022 0.0363 0.0255
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0048 0.1226 0.88
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0048 0.1226 0.88
Loa Loa (eye worm) cytochrome P450 family protein 0.0048 0.1226 0.1226
Trypanosoma brucei unspecified product 0.003 0.0634 0.2679
Trichomonas vaginalis casein kinase II beta chain, putative 0.0076 0.2152 0.2065
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.1089 0.4872
Trypanosoma brucei multidrug resistance protein E 0.0057 0.1528 0.6991
Leishmania major ATP-binding cassette protein subfamily C, member 6, putative 0.0057 0.1528 0.6991
Leishmania major ATP-binding cassette protein subfamily B, member 2, putative 0.0045 0.1122 0.5032
Leishmania major ATP-binding cassette protein subfamily G, member 4, putative 0.0063 0.1706 0.7848
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0757 0.125
Echinococcus granulosus multidrug resistance protein 1 0.0045 0.1122 0.1853
Loa Loa (eye worm) flap endonuclease-1 0.003 0.0612 0.0612
Trichomonas vaginalis casein kinase II beta chain, putative 0.0076 0.2152 0.2065
Trichomonas vaginalis casein kinase II beta chain, putative 0.0076 0.2152 0.2065
Trypanosoma brucei p-glycoprotein 0.0057 0.1528 0.6991
Giardia lamblia ABC transporter, putative 0.0057 0.1528 0.7101
Trichomonas vaginalis ABC transporter, putative 0.0045 0.1122 0.1023
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.1089 0.4872
Echinococcus granulosus dna polymerase eta 0.0073 0.2056 0.3395
Echinococcus granulosus ETS transcription factor Elf 5 0.0012 0.0023 0.0037
Toxoplasma gondii ABC transporter family protein 0.0022 0.0353 0.1641
Brugia malayi cytochrome P450 0.0048 0.1226 0.1226
Schistosoma mansoni elf1 0.0012 0.0023 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.1089 0.4872
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0045 0.1122 0.1023
Trichomonas vaginalis casein kinase II beta chain, putative 0.0022 0.0363 0.0255
Trichomonas vaginalis casein kinase II beta chain, putative 0.0022 0.0363 0.0255
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0048 0.1226 0.1156
Trypanosoma brucei unspecified product 0.0044 0.1089 0.4872
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0012 0.0023 0.0023
Brugia malayi Ets-domain containing protein 0.0083 0.2373 0.2373
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0045 0.1122 0.1023
Echinococcus granulosus multidrug resistance protein 1 0.0025 0.0441 0.0729
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0223 0.0368
Toxoplasma gondii ATP-binding cassette sub-family B member 5 0.0022 0.0353 0.1641
Schistosoma mansoni multidrug resistance protein 0.0057 0.1528 0.1528
Trichomonas vaginalis casein kinase II beta chain, putative 0.0022 0.0363 0.0255
Trypanosoma cruzi multidrug resistance protein E, putative 0.0057 0.1528 0.6991
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.1089 0.4872
Chlamydia trachomatis ABC transporter ATP binding protein/permease 0.0045 0.1122 0.5
Giardia lamblia Hypothetical protein 0.0021 0.0305 0.1415
Leishmania major ATP-binding cassette protein subfamily C, member 8, putative 0.0022 0.0353 0.1325
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0022 0.0353 0.1641
Trypanosoma brucei ABC transporter, mitochondrial, putative 0.0022 0.0353 0.1325
Echinococcus multilocularis GA binding protein alpha chain 0.0083 0.2373 0.3918
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0048 0.1226 0.1156
Plasmodium falciparum DNA repair protein REV1, putative 0.0014 0.0079 0.0365
Leishmania major pentamidine resistance protein 1 0.0057 0.1528 0.6991
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0044 0.1089 0.1798
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0045 0.1122 0.1853
Brugia malayi ABC transporter family protein 0.0022 0.0353 0.0353
Trypanosoma cruzi cytochrome P450, putative 0.0048 0.1226 0.5532
Trypanosoma brucei cytochrome P450, putative 0.0048 0.1226 0.5532
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0048 0.1226 0.5532
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0223 0.0368
Echinococcus multilocularis multidrug resistance protein 1 0.0045 0.1122 0.1853
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0076 0.2152 1
Schistosoma mansoni ATP-binding cassette sub-family B member 6 mitochondrial precursor (abc6) 0.0021 0.0305 0.0305
Schistosoma mansoni flap endonuclease-1 0.0027 0.0517 0.0517
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.1089 0.4872
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0021 0.0305 0.0196
Trichomonas vaginalis casein kinase II beta chain, putative 0.0076 0.2152 0.2065
Loa Loa (eye worm) hypothetical protein 0.0039 0.0917 0.0917
Echinococcus multilocularis geminin 0.0194 0.6056 1
Plasmodium vivax ABC transporter B family member 5, putative 0.0022 0.0353 0.1325
Schistosoma mansoni ABC transporter 0.0053 0.1393 0.1393
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0223 0.0368
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0022 0.0353 0.1641
Leishmania major DNA polymerase kappa, putative 0.0044 0.1089 0.4872
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0057 0.1528 0.6991
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0045 0.1122 0.1023
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0048 0.1226 0.1156
Echinococcus granulosus multidrug resistance protein 1 0.0045 0.1122 0.1853
Loa Loa (eye worm) hypothetical protein 0.0045 0.1122 0.1122
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0757 0.3517
Entamoeba histolytica P-glycoprotein-5 0.0045 0.1122 0.4954
Plasmodium vivax casein kinase II beta chain, putative 0.0076 0.2152 1
Brugia malayi polk-prov protein 0.0014 0.0079 0.0079
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0757 0.0757
Wolbachia endosymbiont of Brugia malayi ABC-type protease secretion system, ATPase and permease component, AprD 0.0022 0.0353 0.5
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0048 0.1226 0.5532
Loa Loa (eye worm) hypothetical protein 0.0044 0.1073 0.1073
Echinococcus granulosus cytochrome P450 2K1 0.0048 0.1226 0.2024
Trichomonas vaginalis casein kinase II beta chain, putative 0.0022 0.0363 0.0255
Echinococcus granulosus ewsr:fli fusion protein type 0.0012 0.0023 0.0037
Trypanosoma brucei DNA polymerase IV, putative 0.0044 0.1089 0.4872
Brugia malayi ABC transporter 0.0021 0.0305 0.0305
Entamoeba histolytica ATP-binding cassette protein, putative 0.0057 0.1528 0.6944
Loa Loa (eye worm) fli-1 protein 0.0252 0.7969 0.7969
Echinococcus multilocularis flap endonuclease 1 0.003 0.0612 0.1011
Leishmania major cytochrome p450-like protein 0.0048 0.1226 0.5532
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0048 0.1226 0.1156
Echinococcus multilocularis multidrug resistance associated protein 4 0.0035 0.0799 0.1319
Loa Loa (eye worm) Csnk2b protein 0.0076 0.2152 0.2152
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0045 0.1122 0.1853
Schistosoma mansoni multidrug resistance protein 0.0045 0.1122 0.1122
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0045 0.1122 0.1023
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0045 0.1122 0.1023
Entamoeba histolytica ATP-binding cassette protein, putative 0.0057 0.1528 0.6944
Entamoeba histolytica ABC transporter, putative 0.0063 0.1706 0.7814
Trichomonas vaginalis abcb9, putative 0.0045 0.1122 0.1023
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0076 0.2152 1
Trichomonas vaginalis DNA helicase recq1, putative 0.0027 0.0535 0.0429
Giardia lamblia Casein kinase II beta chain 0.0076 0.2152 1
Trichomonas vaginalis casein kinase II beta chain, putative 0.0022 0.0363 0.0255
Echinococcus multilocularis ETS transcription factor Elf 2 0.0012 0.0023 0.0037
Schistosoma mansoni hypothetical protein 0.0018 0.0223 0.0223
Plasmodium vivax ABC transporter B family member 4, putative 0.0022 0.0353 0.1325
Giardia lamblia Flap structure-specific endonuclease 0.003 0.0612 0.2845
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0045 0.1122 0.1023
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0022 0.0353 0.0245
Schistosoma mansoni hypothetical protein 0.0052 0.1345 0.1345
Leishmania major DNA polymerase eta, putative 0.0043 0.1045 0.4662
Schistosoma mansoni multidrug resistance protein 0.0057 0.1528 0.1528
Plasmodium falciparum multidrug resistance-associated protein 2 0.0022 0.0353 0.1641
Schistosoma mansoni casein kinase II beta subunit 0.0076 0.2152 0.2152
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0048 0.1226 0.1156
Trypanosoma cruzi cytochrome P450, putative 0.0048 0.1226 0.5532
Giardia lamblia Multidrug resistance-associated protein Mrp2 0.0021 0.0305 0.1415
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0048 0.1226 0.88
Schistosoma mansoni multidrug resistance protein 0.0045 0.1122 0.1122
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.0715 0.1181
Leishmania major flap endonuclease-1 (FEN-1), putative 0.003 0.0612 0.2574
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0045 0.1122 0.1023
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0076 0.2152 1
Brugia malayi Cytochrome P450 family protein 0.0048 0.1226 0.1226
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0057 0.1528 0.7101
Trichomonas vaginalis flap endonuclease-1, putative 0.003 0.0612 0.0507
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0048 0.1226 0.1156
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0076 0.2152 1
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0022 0.0363 0.1233
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0044 0.1089 0.4872
Trichomonas vaginalis casein kinase II beta chain, putative 0.0076 0.2152 0.2065
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.003 0.0612 0.2574
Schistosoma mansoni multidrug resistance protein 0.0045 0.1122 0.1122
Brugia malayi multidrug resistance protein 3 0.0045 0.1122 0.1122
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0111 0.0155
Trypanosoma brucei multidrug resistance-associated protein, putative 0.0057 0.1528 0.6991
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0045 0.1122 0.1853
Plasmodium falciparum casein kinase II beta chain 0.0076 0.2152 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.1089 0.4872
Plasmodium falciparum ABC transporter B family member 5, putative 0.0022 0.0353 0.1641
Entamoeba histolytica P-glycoprotein-1 0.0045 0.1122 0.4954
Schistosoma mansoni glutaminase 0.0313 1 1
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0048 0.1226 0.1156
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0076 0.2152 1
Loa Loa (eye worm) cytochrome P450 0.0048 0.1226 0.1226
Echinococcus granulosus ETS domain containing protein Elk 1 0.0012 0.0023 0.0037
Brugia malayi ABC transporter family protein 0.0053 0.1393 0.1393
Loa Loa (eye worm) hypothetical protein 0.0056 0.148 0.148
Trichomonas vaginalis casein kinase II beta chain, putative 0.0022 0.0363 0.0255
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0044 0.1089 0.1798
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.003 0.0612 0.2845
Brugia malayi ABC transporter family protein 0.0022 0.0353 0.0353
Trichomonas vaginalis ABC transporter, half transporter, putative 0.0045 0.1122 0.1023
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0757 0.125
Brugia malayi Calcitonin receptor-like protein seb-1 0.0057 0.1516 0.1516
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0045 0.1122 0.1023
Echinococcus multilocularis ATP binding cassette sub family B 0.0044 0.1073 0.1773
Entamoeba histolytica deoxycytidyl transferase, putative 0.0044 0.1089 0.4791
Entamoeba histolytica P-glycoprotein 5, putative 0.0045 0.1122 0.4954
Brugia malayi ABC transporter transmembrane region family protein 0.0057 0.1528 0.1528
Entamoeba histolytica P-glycoprotein 6, putative 0.0022 0.0353 0.1188
Entamoeba histolytica ATP-binding cassette protein, putative 0.0057 0.1528 0.6944
Brugia malayi Csnk2b protein 0.0076 0.2152 0.2152
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0045 0.1122 0.1023
Leishmania major p-glycoprotein 0.0045 0.1122 0.5032
Echinococcus multilocularis dna polymerase kappa 0.0044 0.1089 0.1798
Leishmania major cytochrome p450-like protein 0.0048 0.1226 0.5532
Brugia malayi ABC transporter 0.0022 0.0353 0.0353
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0057 0.1528 0.6991
Schistosoma mansoni ATP-binding cassette sub-family B member 7 mitochondrial precursor (abc7) 0.0022 0.0353 0.0353
Echinococcus granulosus multidrug resistance protein 1 0.0045 0.1122 0.1853
Trichomonas vaginalis ABC transporter, putative 0.0045 0.1122 0.1023
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0021 0.0305 0.0196
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0057 0.1516 0.1516
Echinococcus granulosus geminin 0.0194 0.6056 1
Loa Loa (eye worm) ABC transporter 0.0053 0.1393 0.1393
Schistosoma mansoni hypothetical protein 0.0018 0.0223 0.0223
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0024 0.0424 0.1972
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0076 0.2152 0.1776
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0048 0.1226 0.1156
Schistosoma mansoni cytochrome P450 0.0048 0.1226 0.1226
Trypanosoma brucei DNA polymerase IV, putative 0.0044 0.1089 0.4872
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0048 0.1226 0.1156
Entamoeba histolytica P-glycoprotein 6, putative 0.0022 0.0353 0.1188
Onchocerca volvulus 0.0271 0.8615 1
Plasmodium vivax multidrug resistance protein 1, putative 0.0045 0.1122 0.5032
Loa Loa (eye worm) cytochrome P450 family protein 0.0048 0.1226 0.1226
Trypanosoma cruzi ABC transporter, putative 0.0063 0.1706 0.7848
Brugia malayi transcription factor E74 isoform 0.0012 0.0023 0.0023
Plasmodium falciparum ABC transporter B family member 6, putative 0.0022 0.0353 0.1641
Entamoeba histolytica P-glycoprotein-2 0.0045 0.1122 0.4954
Loa Loa (eye worm) cytochrome P450 family protein 0.0048 0.1226 0.1226
Plasmodium vivax ABC transporter G family member 2, putative 0.0063 0.1706 0.7848
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0757 0.125
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0045 0.1122 0.1023
Plasmodium falciparum casein kinase II beta chain 0.0076 0.2152 1
Leishmania major p-glycoprotein e 0.0057 0.1528 0.6991
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0048 0.1226 0.1156
Schistosoma mansoni multidrug resistance protein 0.0021 0.0305 0.0305
Trichomonas vaginalis abcb9, putative 0.0045 0.1122 0.1023
Plasmodium vivax casein kinase II beta chain, putative 0.0076 0.2152 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0757 0.0757
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0012 0.0023 0.0037
Schistosoma mansoni smdr1 0.0022 0.0353 0.0353
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0045 0.1122 0.1853
Echinococcus granulosus ATP binding cassette sub family B 0.0022 0.0353 0.0583
Trypanosoma cruzi DNA polymerase eta, putative 0.0043 0.1045 0.4662
Loa Loa (eye worm) multidrug resistance-associated protein 0.0037 0.0848 0.0848
Echinococcus multilocularis bloom syndrome protein 0.0027 0.0535 0.0884
Leishmania major ATP-binding cassette protein subfamily C, member 1, putative 0.0057 0.1528 0.6991
Entamoeba histolytica P-glycoprotein-2 0.0045 0.1122 0.4954
Trichomonas vaginalis abcb9, putative 0.0045 0.1122 0.1023
Mycobacterium tuberculosis Conserved hypothetical protein 0.0044 0.1089 0.742
Giardia lamblia ABC transporter 0.0061 0.1657 0.77
Plasmodium vivax ABC transporter B family member 6, putative 0.0022 0.0353 0.1325
Plasmodium vivax multidrug resistance-associated protein 1, putative 0.0022 0.0353 0.1325
Loa Loa (eye worm) ABC transporter transmembrane region family protein 0.0057 0.1528 0.1528
Schistosoma mansoni smdr2 0.0045 0.1122 0.1122
Echinococcus multilocularis 0.0022 0.0353 0.0583
Trichomonas vaginalis casein kinase II beta chain, putative 0.0076 0.2152 0.2065
Leishmania major DNA polymerase eta, putative 0.0073 0.2056 0.9534
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0045 0.1122 0.1853
Leishmania major ATP-binding cassette protein subfamily G, member 6, putative 0.0063 0.1706 0.7848
Brugia malayi Cytochrome P450 family protein 0.0048 0.1226 0.1226
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0048 0.1226 0.1156
Trypanosoma brucei ATP-binding cassette protein, putative 0.0063 0.1706 0.7848
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0014 0.0079 0.0365
Echinococcus granulosus multidrug resistance associated protein 1 0.0057 0.1528 0.2524
Mycobacterium ulcerans DNA polymerase IV 0.0044 0.1089 0.1018
Echinococcus granulosus ETS transcription factor Elf 2 0.0012 0.0023 0.0037
Loa Loa (eye worm) hypothetical protein 0.0022 0.0353 0.0353
Onchocerca volvulus 0.0045 0.1122 0.0465
Brugia malayi latrophilin 2 splice variant baaae 0.0039 0.0917 0.0917
Schistosoma mansoni DNA polymerase eta 0.0073 0.2056 0.2056
Loa Loa (eye worm) ets-domain-containing protein 0.0012 0.0023 0.0023
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.1089 0.4872
Plasmodium falciparum multidrug resistance protein 2 0.0022 0.0353 0.1641
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0063 0.1706 0.164
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0022 0.0353 0.1641
Loa Loa (eye worm) CYP4Cod1 0.0048 0.1226 0.1226
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0022 0.0363 0.1233
Echinococcus granulosus multidrug resistance associated protein 7 0.0057 0.1528 0.2524
Trypanosoma cruzi ATP-binding cassette protein, putative 0.0063 0.1706 0.7848
Trichomonas vaginalis set domain proteins, putative 0.0271 0.8615 0.86
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0048 0.1226 0.1156
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0076 0.2152 1
Schistosoma mansoni hypothetical protein 0.0194 0.6056 0.6056
Leishmania major cytochrome p450-like protein 0.0048 0.1226 0.5532
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0048 0.1226 0.88
Echinococcus granulosus ATP binding cassette sub family G 0.0063 0.1706 0.2817
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0238 0.7524 0.7524
Loa Loa (eye worm) ABC transporter 0.0022 0.0353 0.0353
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0083 0.2373 0.2373
Giardia lamblia DNA damage repair protein 0.0014 0.0079 0.0365
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0048 0.1226 0.1156
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0223 0.0368
Loa Loa (eye worm) hypothetical protein 0.0018 0.0223 0.0223
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0223 0.0223
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0048 0.1226 0.88
Trypanosoma cruzi hypothetical protein 0.0035 0.0799 0.3474
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0015 0.0111 0.0155
Loa Loa (eye worm) glutaminase 0.0313 1 1
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0048 0.1226 0.88
Leishmania major ATP-binding cassette protein subfamily B, member 3, putative 0.0022 0.0353 0.1325
Entamoeba histolytica ATP-binding cassette protein, putative 0.0057 0.1528 0.6944
Giardia lamblia DINP protein human, muc B family 0.0044 0.1089 0.5059
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0048 0.1226 0.88
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0023
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0022 0.0353 0.0277
Echinococcus multilocularis multidrug resistance associated protein 1 0.0057 0.1528 0.2524
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0063 0.1706 0.164
Toxoplasma gondii ATP-binding cassette transporter ABC.B1 0.0045 0.1122 0.5213
Loa Loa (eye worm) hypothetical protein 0.0073 0.2056 0.2056
Schistosoma mansoni ATP-binding cassette sub-family g2 (white protein) (abcg2) 0.0063 0.1706 0.1706
Trichomonas vaginalis ABC transporter, putative 0.0045 0.1122 0.1023
Trichomonas vaginalis casein kinase II beta chain, putative 0.0022 0.0363 0.0255
Echinococcus multilocularis multidrug resistance protein 1 0.0025 0.0441 0.0729
Plasmodium falciparum ABC transporter B family member 3, putative 0.0022 0.0353 0.1641
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0063 0.1706 0.164
Giardia lamblia Multidrug resistance-associated protein 1 0.0056 0.148 0.6875
Trichomonas vaginalis casein kinase II beta chain, putative 0.0022 0.0363 0.0255
Entamoeba histolytica ABC transporter, putative 0.0057 0.1528 0.6944
Echinococcus granulosus ATP binding cassette sub family B 0.0021 0.0305 0.0503
Trichomonas vaginalis casein kinase II beta chain, putative 0.0076 0.2152 0.2065
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0048 0.1226 0.88
Loa Loa (eye worm) hypothetical protein 0.0057 0.1528 0.1528
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0048 0.1226 0.88
Schistosoma mansoni hypothetical protein 0.0018 0.0223 0.0223
Echinococcus multilocularis GPCR, family 2 0.0018 0.0223 0.0368
Echinococcus multilocularis casein kinase ii subunit beta 0.0076 0.2152 0.3554
Plasmodium falciparum multidrug resistance-associated protein 1 0.0022 0.0353 0.1641
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0045 0.1122 0.1122
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0045 0.1122 0.1853
Plasmodium falciparum multidrug resistance protein 1 0.0045 0.1122 0.5213
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.1089 0.4872
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0045 0.1122 0.1023
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0045 0.1122 0.1023
Echinococcus granulosus multidrug resistance associated protein 4 0.0035 0.0799 0.1319
Loa Loa (eye worm) hypothetical protein 0.0057 0.1528 0.1528
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0048 0.1226 0.1156
Trichomonas vaginalis glutaminase, putative 0.0313 1 1
Trypanosoma brucei ABC transporter of the mitochondrion, putative 0.0022 0.0353 0.1325
Mycobacterium tuberculosis Probable conserved transmembrane ATP-binding protein ABC transporter 0.0052 0.1345 1
Brugia malayi ImpB/MucB/SamB family protein 0.0044 0.1089 0.1089
Trichomonas vaginalis taga, putative 0.0045 0.1122 0.1023
Echinococcus granulosus dna polymerase kappa 0.0044 0.1089 0.1798
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0048 0.1226 0.5532
Trypanosoma brucei DNA polymerase IV, putative 0.0044 0.1089 0.4872
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0034 0.0757 0.0757
Trichomonas vaginalis multidrug resistance protein 1, 2, putative 0.0045 0.1122 0.1023
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.1089 0.4872
Leishmania major ATP-binding cassette protein subfamily C, member 2, putative 0.0057 0.1528 0.6991
Giardia lamblia MRP-like ABC transporter 0.0057 0.1528 0.7101
Trichomonas vaginalis casein kinase II beta chain, putative 0.0076 0.2152 0.2065
Giardia lamblia Casein kinase II beta chain 0.0022 0.0363 0.1684
Loa Loa (eye worm) hypothetical protein 0.0021 0.0305 0.0305
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0634 0.2679
Echinococcus granulosus ATP binding cassette sub family G 0.0063 0.1706 0.2817
Loa Loa (eye worm) hypothetical protein 0.0138 0.421 0.421
Trichomonas vaginalis DNA helicase recq, putative 0.0027 0.0535 0.0429
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0076 0.2152 1
Brugia malayi multidrug Resistance Protein family member (mrp-5), putative 0.0022 0.0353 0.0353
Trypanosoma brucei DNA polymerase eta, putative 0.0073 0.2056 0.9534
Brugia malayi multidrug resistance related protein 1 0.0057 0.1528 0.1528
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0048 0.1226 0.1156
Echinococcus granulosus GPCR family 2 0.0018 0.0223 0.0368
Mycobacterium ulcerans glutaminase 0.0313 1 1
Trichomonas vaginalis casein kinase II beta chain, putative 0.0022 0.0363 0.0255
Trichomonas vaginalis protein kinase ck2-beta, putative 0.0022 0.0363 0.0255
Loa Loa (eye worm) RecQ helicase 0.0027 0.0535 0.0535
Brugia malayi hypothetical protein 0.0022 0.0353 0.0353
Schistosoma mansoni hypothetical protein 0.0012 0.0023 0.0023
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0000000001713 0.00000000079586
Echinococcus multilocularis ATP binding cassette sub family B 0.0022 0.0353 0.0583
Trypanosoma cruzi ABC transporter, mitochondrial, putative 0.0022 0.0353 0.1325
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.1089 0.4872
Echinococcus granulosus ATP binding cassette sub family G 0.0063 0.1706 0.2817
Mycobacterium leprae putative cytochrome p450 0.0048 0.1226 1
Echinococcus granulosus GA binding protein alpha chain 0.0083 0.2373 0.3918
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0057 0.1516 0.1516
Echinococcus multilocularis protein C ets 2 0.0012 0.0023 0.0037
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.1089 0.4872
Brugia malayi ABC transporter transmembrane region family protein 0.0022 0.0353 0.0353
Loa Loa (eye worm) multidrug resistance protein 3 0.0045 0.1122 0.1122
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0012 0.0023 0.0023
Mycobacterium ulcerans transmembrane ABC transporter ATP-binding protein 0.0022 0.0353 0.0277
Echinococcus granulosus flap endonuclease 1 0.003 0.0612 0.1011
Mycobacterium ulcerans drugs-transport transmembrane ATP-binding protein ABC transporter 0.0022 0.0353 0.0277
Echinococcus multilocularis ewsr:fli fusion protein type 0.0012 0.0023 0.0037
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.1089 0.4872
Toxoplasma gondii cytochrome p450 superfamily protein 0.0048 0.1226 0.5695
Trichomonas vaginalis casein kinase II beta chain, putative 0.0022 0.0363 0.0255
Trichomonas vaginalis DNA polymerase eta, putative 0.0044 0.1089 0.0989
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0048 0.1226 0.1156
Loa Loa (eye worm) ABC transporter 0.0022 0.0353 0.0353
Brugia malayi Fli-1 protein 0.0252 0.7969 0.7969
Brugia malayi P-glycoprotein-like protein 0.0022 0.0353 0.0353
Brugia malayi casein kinase II, putaitve 0.0022 0.0363 0.0363
Echinococcus multilocularis dna polymerase eta 0.0073 0.2056 0.3395
Echinococcus granulosus bloom syndrome protein 0.0027 0.0535 0.0884
Trichomonas vaginalis casein kinase II beta chain, putative 0.0076 0.2152 0.2065
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0048 0.1226 0.88
Schistosoma mansoni hypothetical protein 0.0012 0.0023 0.0023
Trypanosoma cruzi multidrug resistance-associated protein, putative 0.0057 0.1528 0.6991
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0044 0.1089 0.1089
Echinococcus granulosus ETS transcription factor Elf 2 0.0012 0.0023 0.0037
Toxoplasma gondii ATP-binding cassette G family transporter ABCG84 0.0063 0.1706 0.7926
Trichomonas vaginalis casein kinase II beta chain, putative 0.0022 0.0363 0.0255
Toxoplasma gondii ABC transporter, putative 0.0022 0.0353 0.1641
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0045 0.1122 0.1853
Echinococcus multilocularis ATP binding cassette sub family G 0.0063 0.1706 0.2817
Entamoeba histolytica multidrug resistance protein, putative 0.0057 0.1528 0.6944
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0045 0.1122 0.1023
Leishmania major ABC-thiol transporter 0.0057 0.1528 0.6991
Loa Loa (eye worm) hypothetical protein 0.0045 0.1122 0.1122
Giardia lamblia Multidrug resistance-associated protein 1 0.0057 0.1528 0.7101
Entamoeba histolytica Flap nuclease, putative 0.003 0.0612 0.2457
Brugia malayi DNA-binding protein D-ETS-3 0.0012 0.0023 0.0023
Toxoplasma gondii ABC transporter transmembrane region domain-containing protein 0.0045 0.1122 0.5213
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0045 0.1122 0.1023
Trypanosoma brucei ABC transporter, putative 0.0063 0.1706 0.7848
Entamoeba histolytica P-glyco protein 6, putative 0.0045 0.1122 0.4954
Echinococcus multilocularis ATP binding cassette sub family B 0.0022 0.0353 0.0583
Trypanosoma brucei DNA polymerase kappa, putative 0.003 0.0634 0.2679
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0044 0.1089 0.0989
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0045 0.1122 0.1853
Schistosoma mansoni hypothetical protein 0.0039 0.0917 0.0917
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0048 0.1226 0.5532
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0045 0.1122 0.1023
Echinococcus multilocularis ATP binding cassette sub family G 0.0063 0.1706 0.2817
Echinococcus granulosus ETS transcription factor Elf 1 0.0012 0.0023 0.0037
Schistosoma mansoni multidrug resistance protein 0.0057 0.1528 0.1528
Trichomonas vaginalis casein kinase II beta chain, putative 0.0022 0.0363 0.0255
Schistosoma mansoni hypothetical protein 0.0194 0.6056 0.6056
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0048 0.1226 0.88
Wolbachia endosymbiont of Brugia malayi ABC-type multidrug transport system, ATPase and permease component 0.0022 0.0353 0.5
Trichomonas vaginalis casein kinase II beta chain, putative 0.0076 0.2152 0.2065
Schistosoma mansoni multidrug resistance protein 0.0022 0.0353 0.0353
Brugia malayi Cytochrome P450 family protein 0.0048 0.1226 0.1226
Trypanosoma brucei unspecified product 0.003 0.0634 0.2679
Plasmodium vivax ABC transporter B family member 7, putative 0.0022 0.0353 0.1325
Brugia malayi Ets-domain containing protein 0.0083 0.2373 0.2373
Brugia malayi Pre-SET motif family protein 0.0238 0.7524 0.7524
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0048 0.1226 0.1156
Brugia malayi Cytochrome P450 family protein 0.0048 0.1226 0.1226
Trypanosoma cruzi DNA polymerase eta, putative 0.0073 0.2056 0.9534
Trichomonas vaginalis ATP-binding cassette transporter, putative 0.0045 0.1122 0.1023
Loa Loa (eye worm) casein kinase II 0.0022 0.0363 0.0363
Entamoeba histolytica P-glycoprotein 5, putative 0.0021 0.0305 0.095
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0048 0.1226 0.5532
Schistosoma mansoni multidrug resistance protein 0.0057 0.1528 0.1528
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0048 0.1226 0.1156
Loa Loa (eye worm) hypothetical protein 0.0012 0.0023 0.0023
Schistosoma mansoni terminal deoxycytidyl transferase 0.0044 0.1089 0.1089
Entamoeba histolytica P-glycoprotein-2, putative 0.0021 0.0305 0.095
Plasmodium falciparum flap endonuclease 1 0.003 0.0612 0.2845
Brugia malayi Ets-domain containing protein 0.0012 0.0023 0.0023
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0757 0.0757
Echinococcus multilocularis ATP binding cassette sub family G 0.0063 0.1706 0.2817
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0012 0.0023 0.0023
Plasmodium falciparum ABC transporter G family member 2 0.0063 0.1706 0.7926
Plasmodium vivax flap endonuclease 1, putative 0.003 0.0612 0.2574
Brugia malayi Bloom's syndrome protein homolog 0.0027 0.0535 0.0535
Loa Loa (eye worm) hypothetical protein 0.0014 0.0079 0.0079
Trichomonas vaginalis casein kinase II beta chain, putative 0.0076 0.2152 0.2065
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0044 0.1089 0.1089
Brugia malayi Pre-SET motif family protein 0.0034 0.0757 0.0757
Brugia malayi ABC transporter family protein 0.0022 0.0353 0.0353
Leishmania major ATP-binding cassette protein subfamily C, member 5, putative 0.0057 0.1528 0.6991
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0014 0.0079 0.0365
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0223 0.0223
Mycobacterium ulcerans DNA polymerase IV 0.0044 0.1089 0.1018
Trichomonas vaginalis lipid A export ATP-binding/permease protein msba, putative 0.0045 0.1122 0.1023
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0048 0.1226 0.88
Trichomonas vaginalis casein kinase II beta chain, putative 0.0076 0.2152 0.2065

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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