Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0093 | 0.3878 | 1 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0093 | 0.3878 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0035 | 0.0862 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0862 | 0.0862 |
Loa Loa (eye worm) | carboxylesterase | 0.0209 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0093 | 0.3878 | 0.3878 |
Echinococcus granulosus | acetylcholinesterase | 0.0209 | 1 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0093 | 0.3878 | 0.3878 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0035 | 0.0862 | 0.0862 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.3878 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0035 | 0.0862 | 0.0862 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0862 | 0.0862 |
Brugia malayi | Carboxylesterase family protein | 0.0209 | 1 | 1 |
Echinococcus multilocularis | neuroligin | 0.0035 | 0.0862 | 0.0862 |
Brugia malayi | hypothetical protein | 0.0035 | 0.0862 | 0.0862 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0035 | 0.0862 | 0.0862 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0035 | 0.0862 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.3878 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.3878 | 1 |
Schistosoma mansoni | kinase | 0.0047 | 0.1481 | 0.1481 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1364 | 0.1364 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0046 | 0.1417 | 0.3654 |
Echinococcus granulosus | carboxylesterase 5A | 0.0209 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.1364 | 0.1364 |
Echinococcus multilocularis | acetylcholinesterase | 0.0209 | 1 | 1 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0093 | 0.3878 | 0.3878 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0093 | 0.3878 | 0.3878 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0093 | 0.3878 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0035 | 0.0862 | 0.0862 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0862 | 0.0862 |
Echinococcus granulosus | neuroligin | 0.0035 | 0.0862 | 0.0862 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0035 | 0.0862 | 0.0862 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0093 | 0.3878 | 1 |
Trypanosoma brucei | polo-like protein kinase | 0.0093 | 0.3878 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1364 | 0.1364 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.3878 | 1 |
Giardia lamblia | Kinase, PLK | 0.0093 | 0.3878 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0862 | 0.0862 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.1364 | 0.1364 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0035 | 0.0862 | 0.0862 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0035 | 0.0862 | 0.0862 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0035 | 0.0862 | 0.0862 |
Echinococcus granulosus | acetylcholinesterase | 0.0209 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0209 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0862 | 0.0862 |
Schistosoma mansoni | acetylcholinesterase | 0.0035 | 0.0862 | 0.0862 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0035 | 0.0862 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0035 | 0.0862 | 0.0862 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0862 | 0.0862 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0035 | 0.0862 | 0.0862 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.3878 | 1 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0035 | 0.0862 | 0.2224 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.1364 | 0.1364 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0035 | 0.0862 | 0.0862 |
Loa Loa (eye worm) | hypothetical protein | 0.0209 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0209 | 1 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0046 | 0.1417 | 0.3654 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0209 | 1 | 1 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0093 | 0.3878 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0035 | 0.0862 | 0.0862 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0035 | 0.0862 | 0.0862 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0862 | 0.0862 |
Schistosoma mansoni | gliotactin | 0.0035 | 0.0862 | 0.0862 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1364 | 0.1364 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0093 | 0.3878 | 0.3878 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.3878 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0035 | 0.0862 | 0.0862 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0035 | 0.0862 | 0.2224 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0035 | 0.0862 | 0.0862 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.1364 | 0.1364 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0035 | 0.0862 | 0.0862 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.1364 | 0.1364 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0209 | 1 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0035 | 0.0862 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0093 | 0.3878 | 1 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0035 | 0.0862 | 0.0862 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.1364 | 0.1364 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.