Detailed information for compound 624002

Basic information

Technical information
  • TDR Targets ID: 624002
  • Name: N-[4-(3,4-dimethylphenyl)-1,3-thiazol-2-yl]-2 ,4-dinitrobenzamide
  • MW: 398.393 | Formula: C18H14N4O5S
  • H donors: 1 H acceptors: 6 LogP: 4.17 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(c1ccc(cc1[N+](=O)[O-])[N+](=O)[O-])Nc1scc(n1)c1ccc(c(c1)C)C
  • InChi: 1S/C18H14N4O5S/c1-10-3-4-12(7-11(10)2)15-9-28-18(19-15)20-17(23)14-6-5-13(21(24)25)8-16(14)22(26)27/h3-9H,1-2H3,(H,19,20,23)
  • InChiKey: XJZLCZFWAWOTHK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[4-(3,4-dimethylphenyl)thiazol-2-yl]-2,4-dinitro-benzamide
  • N-[4-(3,4-dimethylphenyl)-2-thiazolyl]-2,4-dinitrobenzamide
  • N-[4-(3,4-dimethylphenyl)-1,3-thiazol-2-yl]-2,4-dinitro-benzamide
  • Oprea1_566663
  • ZINC02699356

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0042 0.0061
Loa Loa (eye worm) RNA binding protein 0.0063 0.0122 0.0389
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0459 0.1378 0.2172
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.004 0.0049 0.0155
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0038 0.0042 0.006
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0038 0.0042 0.0038
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.0042 0.006
Brugia malayi RNA, U transporter 1 0.0086 0.0195 0.0586
Trypanosoma cruzi pyruvate kinase 2, putative 0.0036 0.0038 0.0197
Mycobacterium tuberculosis Probable esterase LipL 0.0182 0.0501 0.1293
Brugia malayi Nuclear hormone receptor family member nhr-3 0.004 0.0049 0.0117
Schistosoma mansoni nuclear hormone receptor 0.004 0.0049 0.0072
Loa Loa (eye worm) G-protein coupled receptor 0.0038 0.0042 0.0132
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0095 0.0224 1
Schistosoma mansoni myosin xvIII 0.0038 0.0042 0.0061
Echinococcus multilocularis carboxylesterase 5A 0.101 0.3126 0.3124
Schistosoma mansoni cpg binding protein 0.018 0.0493 0.0775
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.004 0.0049 0.0155
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0096 0.0228 0.1187
Trichomonas vaginalis ap endonuclease, putative 0.0095 0.0224 0.3386
Brugia malayi Carboxylesterase family protein 0.0171 0.0464 0.1449
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0089 0.0086
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0038 0.0341
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0119 0.0301 0.0734
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Brugia malayi intermediate filament protein 0.0053 0.0091 0.0251
Plasmodium vivax thioredoxin reductase, putative 0.0047 0.0071 0.1148
Echinococcus granulosus acetylcholinesterase 0.101 0.3126 0.4936
Schistosoma mansoni thyroid hormone receptor 0.004 0.0049 0.0072
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0102 0.0247 0.1282
Echinococcus multilocularis pyruvate kinase 0.0036 0.0038 0.0034
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0102 0.0247 0.1282
Brugia malayi Heterochromatin protein 1 0.007 0.0146 0.0429
Mycobacterium ulcerans carboxylesterase, LipT 0.0171 0.0464 0.4533
Echinococcus granulosus neuropeptides capa receptor 0.0038 0.0042 0.006
Echinococcus multilocularis somatostatin receptor 0.0038 0.0042 0.0038
Loa Loa (eye worm) hypothetical protein 0.0172 0.0467 0.1492
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0048 0.0249
Entamoeba histolytica hypothetical protein 0.0143 0.0375 1
Echinococcus granulosus mixed lineage leukemia protein mll 0.0043 0.006 0.0089
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0036 0.0037 0.0053
Giardia lamblia Pyruvate kinase 0.0036 0.0038 0.0954
Plasmodium falciparum pyruvate kinase 0.0036 0.0038 0.1058
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0107 0.0263 0.0628
Toxoplasma gondii histone lysine methyltransferase SET1 0.0324 0.0949 1
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0037 0.004 0.0036
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0038 0.0042 0.0038
Echinococcus multilocularis importin subunit beta 1 0.003 0.0018 0.0015
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0075 0.1138
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0048 0.0204
Brugia malayi Sodium:solute symporter family protein 0.0037 0.004 0.0088
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.004 0.0049 0.0045
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0049 0.0117
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0049 0.0072
Mycobacterium ulcerans hypothetical protein 0.0332 0.0977 1
Brugia malayi nuclear receptor NHR-88 0.004 0.0049 0.0117
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.004 0.0049 0.0511
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0037 0.0144
Echinococcus granulosus g protein coupled receptor 0.0038 0.0042 0.006
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0016 0.002
Brugia malayi jmjC domain containing protein 0.0097 0.0229 0.0695
Trypanosoma brucei unspecified product 0.004 0.0048 0.0204
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0081 0.1228
Onchocerca volvulus 0.0038 0.0042 0.0398
Plasmodium vivax SET domain protein, putative 0.0033 0.0026 0.0204
Schistosoma mansoni pyruvate kinase 0.0036 0.0038 0.0055
Onchocerca volvulus 0.0038 0.0042 0.0398
Plasmodium vivax glutathione reductase, putative 0.0047 0.0071 0.1148
Echinococcus granulosus neuropeptide Y receptor 0.0038 0.0042 0.006
Brugia malayi F/Y-rich N-terminus family protein 0.0063 0.0121 0.0349
Mycobacterium leprae conserved hypothetical protein 0.0182 0.0501 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0172 0.0467 0.0463
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0042 0.0038
Echinococcus granulosus peptide allatostatin:somatostatin 0.0038 0.0042 0.006
Echinococcus granulosus somatostatin receptor 0.0038 0.0042 0.006
Onchocerca volvulus 0.0171 0.0464 0.6935
Trichomonas vaginalis chromobox protein, putative 0.007 0.0146 0.2205
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0049 0.0117
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0172 0.0467 0.0732
Echinococcus granulosus tachykinin peptides receptor 99D 0.0038 0.0042 0.006
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0171 0.0464 0.0728
Brugia malayi Carboxylesterase family protein 0.0171 0.0464 0.1449
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0054 0.0093 0.0089
Mycobacterium ulcerans hypothetical protein 0.0182 0.0501 0.4927
Schistosoma mansoni biogenic amine (5HT) receptor 0.0038 0.0042 0.0061
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.004 0.0049 0.0072
Echinococcus multilocularis neuropeptide s receptor 0.1401 0.4368 0.4366
Loa Loa (eye worm) hypothetical protein 0.0053 0.0091 0.0288
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0122 0.0352
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Loa Loa (eye worm) hypothetical protein 0.004 0.0049 0.0155
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.004 0.0048 0.007
Schistosoma mansoni ap endonuclease 0.0095 0.0224 0.0349
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0036 0.0037 0.019
Giardia lamblia Kinase, PLK 0.0096 0.0228 0.9202
Loa Loa (eye worm) hypothetical protein 0.0036 0.0038 0.012
Schistosoma mansoni neuropeptide receptor 0.0038 0.0042 0.0061
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0459 0.1378 0.4405
Mycobacterium tuberculosis Probable reductase 0.0107 0.0263 0.0628
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0459 0.1378 0.1374
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0037 0.004 0.0057
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0081 0.1228
Echinococcus multilocularis beta LACTamase domain containing family member 0.0182 0.0501 0.0497
Toxoplasma gondii aldehyde dehydrogenase 0.025 0.0715 0.7495
Giardia lamblia Kinase, CMGC MAPK 0.0102 0.0247 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0033 0.0026 0.0035
Brugia malayi MAP kinase sur-1 0.0102 0.0247 0.0753
Schistosoma mansoni importin beta-1 0.003 0.0018 0.0024
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.005 0.0081 0.1228
Mycobacterium tuberculosis Conserved hypothetical protein 0.0332 0.0977 0.2624
Brugia malayi G protein-coupled receptor F59B2.13 0.0038 0.0042 0.0093
Brugia malayi hypothetical protein 0.0038 0.0042 0.0093
Echinococcus multilocularis serotonin receptor 0.0038 0.0042 0.0038
Brugia malayi putative neuropeptide receptor NPR1 0.0038 0.0042 0.0093
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0089 0.0204 0.1059
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0042 0.0061
Echinococcus multilocularis orexin receptor type 2 0.0038 0.0042 0.0038
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0042 0.0061
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0095 0.0224 0.0349
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0045 0.0675
Onchocerca volvulus 0.0095 0.0224 0.3219
Brugia malayi putative neuropeptide receptor 0.0038 0.0042 0.0093
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0026 0.0036
Echinococcus granulosus snurportin 1 0.0323 0.0946 0.1489
Trypanosoma cruzi polo-like protein kinase, putative 0.0096 0.0228 0.1187
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0032 0.0025 0.0371
Echinococcus granulosus orexin receptor type 2 0.0038 0.0042 0.006
Loa Loa (eye worm) hypothetical protein 0.0182 0.0501 0.16
Onchocerca volvulus Bile acid receptor homolog 0.004 0.0049 0.0511
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0038 0.0042 0.0038
Schistosoma mansoni retinoic acid receptor RXR 0.004 0.0049 0.0072
Schistosoma mansoni hypothetical protein 0.1547 0.483 0.7628
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0459 0.1378 0.2172
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0143 0.0375 0.0587
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Schistosoma mansoni gliotactin 0.0171 0.0464 0.0728
Echinococcus granulosus pyruvate kinase 0.0036 0.0038 0.0054
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0046 0.0069 0.0819
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.0296 0.0944
Echinococcus multilocularis chromobox protein 1 0.007 0.0146 0.0142
Echinococcus multilocularis neuropeptide Y receptor 0.0038 0.0042 0.0038
Echinococcus granulosus serotonin receptor 0.0038 0.0042 0.006
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0037 0.004 0.0036
Loa Loa (eye worm) hypothetical protein 0.0171 0.0464 0.1482
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0042 0.0038
Loa Loa (eye worm) hypothetical protein 0.0171 0.0464 0.1482
Echinococcus granulosus solute carrier family 5 0.0037 0.004 0.0057
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0542 0.1643 0.5237
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0042 0.0038
Toxoplasma gondii pyruvate kinase PyK1 0.0036 0.0038 0.0236
Brugia malayi Intermediate filament tail domain containing protein 0.0053 0.0091 0.0251
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0228 0.3452
Loa Loa (eye worm) hypothetical protein 0.0171 0.0464 0.1482
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0048 0.0204
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0042 0.0061
Schistosoma mansoni hypothetical protein 0.0172 0.0467 0.0733
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0045 0.0675
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0016 0.002
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.0296 0.0944
Onchocerca volvulus 0.0038 0.0042 0.0398
Brugia malayi GH02984p 0.0336 0.0988 0.3132
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0042 0.006
Echinococcus granulosus lamin dm0 0.0053 0.0091 0.0138
Schistosoma mansoni transcription factor LCR-F1 0.0143 0.0375 0.0587
Echinococcus granulosus acetylcholinesterase 0.101 0.3126 0.4936
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.0048 0.0114
Leishmania major pyruvate kinase 0.0036 0.0038 0.0197
Schistosoma mansoni lamin 0.0053 0.0091 0.0138
Onchocerca volvulus 0.0038 0.0042 0.0398
Mycobacterium tuberculosis Conserved protein 0.0182 0.0501 0.1293
Schistosoma mansoni inositol transporter 0.0037 0.004 0.0058
Trypanosoma cruzi hypothetical protein, conserved 0.0182 0.0501 0.2601
Echinococcus granulosus g protein coupled receptor 0.0038 0.0042 0.006
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0038 0.0042 0.006
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0102 0.0247 0.1282
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0037 0.0052
Onchocerca volvulus 0.0038 0.0042 0.0398
Brugia malayi latrophilin 2 splice variant baaae 0.0371 0.1099 0.3488
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0102 0.0247 0.1282
Loa Loa (eye worm) hypothetical protein 0.0182 0.0501 0.16
Loa Loa (eye worm) hypothetical protein 0.0029 0.0016 0.0049
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0052 0.0049
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0228 0.3452
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0045 0.0675
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0038 0.0341
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Loa Loa (eye worm) carboxylesterase 0.0171 0.0464 0.1482
Brugia malayi G-protein coupled receptor 0.0038 0.0042 0.0093
Brugia malayi hypothetical protein 0.0038 0.0042 0.0093
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0122 0.0389
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0038 0.0042 0.0061
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.0042 0.0038
Onchocerca volvulus 0.0038 0.0042 0.0398
Echinococcus multilocularis cpg binding protein 0.018 0.0493 0.049
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.004 0.0049 0.0045
Brugia malayi beta-lactamase 0.0182 0.0501 0.1568
Loa Loa (eye worm) hypothetical protein 0.0051 0.0083 0.0263
Brugia malayi Thioredoxin reductase 0.0047 0.0071 0.019
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0102 0.0247 0.1282
Echinococcus granulosus pyruvate kinase 0.0036 0.0038 0.0054
Echinococcus granulosus biogenic amine 5HT receptor 0.0038 0.0042 0.006
Echinococcus multilocularis g-protein coupled receptor 0.0038 0.0042 0.0038
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0122 0.0188
Schistosoma mansoni hypothetical protein 0.0038 0.0042 0.0061
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0037 0.019
Onchocerca volvulus 0.0053 0.0091 0.1158
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0036 0.0037 0.0053
Chlamydia trachomatis pyruvate kinase 0.0036 0.0038 0.5
Echinococcus granulosus chromobox protein 1 0.007 0.0146 0.0225
Brugia malayi RE15519p 0.0038 0.0042 0.0093
Treponema pallidum exodeoxyribonuclease (exoA) 0.0095 0.0224 0.5
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Mycobacterium leprae Probable lipase LipE 0.0182 0.0501 1
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0247 0.3731
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0036 0.0037 0.0975
Brugia malayi Nuclear hormone receptor family member nhr-14 0.004 0.0049 0.0117
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0323 0.0946 0.3024
Echinococcus granulosus neuropeptide receptor A26 0.1401 0.4368 0.6898
Loa Loa (eye worm) hypothetical protein 0.003 0.0018 0.0057
Schistosoma mansoni opsin-like receptor 0.0038 0.0042 0.0061
Brugia malayi GnHR receptor homolog 0.0038 0.0042 0.0093
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0247 0.3731
Brugia malayi sulfakinin receptor protein 0.0038 0.0042 0.0093
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.004 0.0048 0.0028
Echinococcus granulosus lysine specific demethylase 5A 0.0045 0.0066 0.0099
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0081 0.1228
Onchocerca volvulus Neuropeptide F receptor homolog 0.0038 0.0042 0.0398
Schistosoma mansoni neuropeptide receptor 0.0038 0.0042 0.0061
Schistosoma mansoni high-affinity choline transporter 0.0336 0.0988 0.1556
Brugia malayi hypothetical protein 0.0038 0.0042 0.0093
Echinococcus multilocularis lamin 0.0053 0.0091 0.0087
Echinococcus multilocularis sex peptide receptor 0.0038 0.0042 0.0038
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0037 0.0033
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0026 0.0106
Echinococcus granulosus dna polymerase eta 0.004 0.0048 0.007
Onchocerca volvulus 0.004 0.0049 0.0511
Schistosoma mansoni BC026374 protein (S09 family) 0.0171 0.0464 0.0728
Echinococcus granulosus neuropeptide receptor 0.0038 0.0042 0.006
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0095 0.0224 0.4294
Schistosoma mansoni lamin 0.0053 0.0091 0.0138
Echinococcus granulosus polycomb protein SCMH1 0.0046 0.0069 0.0103
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0016 0.0012
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0171 0.0464 0.0728
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0049 0.0045
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.004 0.0049 0.0072
Echinococcus multilocularis mitogen activated protein kinase 3 0.0102 0.0247 0.0243
Loa Loa (eye worm) thioredoxin reductase 0.0047 0.0071 0.0227
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0037 0.004 0.0036
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0036 0.0037 0.019
Brugia malayi Importin beta-1 subunit 0.003 0.0018 0.0018
Echinococcus granulosus GPCR family 2 0.0172 0.0467 0.0732
Schistosoma mansoni neuropeptide receptor 0.0038 0.0042 0.0061
Echinococcus granulosus 7TM GPCR rhodopsin 0.0038 0.0042 0.006
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.0042 0.006
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0042 0.0038
Echinococcus granulosus para nitrobenzyl esterase 0.0171 0.0464 0.0727
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0042 0.006
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Onchocerca volvulus 0.0053 0.0091 0.1158
Echinococcus granulosus high affinity choline transporter 1 0.0336 0.0988 0.1556
Echinococcus multilocularis neuropeptides capa receptor 0.0038 0.0042 0.0038
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0048 0.0249
Loa Loa (eye worm) hypothetical protein 0.004 0.0049 0.0155
Leishmania major DNA polymerase kappa, putative 0.004 0.0048 0.0249
Brugia malayi mbt repeat family protein 0.0046 0.0069 0.0181
Echinococcus granulosus FTZ F1 alpha 0.004 0.0049 0.0072
Brugia malayi Carboxylesterase family protein 0.101 0.3126 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0049 0.0155
Trichomonas vaginalis pyruvate kinase, putative 0.0036 0.0038 0.0572
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0089 0.0246
Brugia malayi beta-lactamase family protein 0.0182 0.0501 0.1568
Echinococcus multilocularis ecdysone induced protein 78C 0.004 0.0049 0.0045
Schistosoma mansoni biogenic amine receptor 0.0038 0.0042 0.0061
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.0048 0.0724
Loa Loa (eye worm) pyruvate kinase-PB 0.0025 0.0003 0.0008
Trypanosoma cruzi DNA polymerase eta, putative 0.004 0.0048 0.0249
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0048 0.0204
Loa Loa (eye worm) hypothetical protein 0.0036 0.0037 0.0116
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0228 0.0356
Echinococcus granulosus neuropeptide receptor 0.0038 0.0042 0.006
Plasmodium falciparum glutathione reductase 0.0047 0.0071 0.2673
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0172 0.0467 0.1459
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0459 0.1378 0.4384
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0097 0.0229 0.0356
Echinococcus multilocularis survival motor neuron protein 1 0.0466 0.14 0.1397
Echinococcus multilocularis ubiquitin specific protease 41 0.0036 0.0037 0.0033
Entamoeba histolytica serine/threonine protein kinase, putative 0.0096 0.0228 0.6094
Schistosoma mansoni neuropeptide F-like receptor 0.0038 0.0042 0.0061
Brugia malayi glutathione reductase 0.0047 0.0071 0.019
Schistosoma mansoni opsin-like receptor 0.0038 0.0042 0.0061
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0049 0.0117
Loa Loa (eye worm) hypothetical protein 0.0171 0.0464 0.1482
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.004 0.0049 0.0155
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0048 0.0204
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0038 0.0042 0.0093
Brugia malayi hypothetical protein 0.0171 0.0464 0.1449
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0171 0.0464 0.0727
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.004 0.0049 0.0072
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0038 0.0042 0.0061
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0042 0.0061
Plasmodium falciparum importin beta, putative 0.003 0.0018 0.011
Schistosoma mansoni hypothetical protein 0.0172 0.0467 0.0733
Onchocerca volvulus 0.0038 0.0042 0.0398
Schistosoma mansoni hypothetical protein 0.0038 0.0042 0.0061
Loa Loa (eye worm) hypothetical protein 0.0031 0.0021 0.0064
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.004 0.0049 0.0045
Brugia malayi G protein-coupled receptor 0.0038 0.0042 0.0093
Loa Loa (eye worm) mbt repeat family protein 0.0046 0.0069 0.0219
Brugia malayi Calcitonin receptor-like protein seb-1 0.0542 0.1643 0.5237
Trypanosoma brucei DNA polymerase eta, putative 0.004 0.0048 0.0204
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0042 0.0061
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0362 0.1071 0.1688
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0095 0.0224 0.0715
Brugia malayi ORL1-like opioid receptor 0.0038 0.0042 0.0093
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0038 0.0042 0.0398
Brugia malayi hypothetical protein 0.0038 0.0042 0.0093
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0048 0.0107
Echinococcus granulosus thioredoxin glutathione reductase 0.0047 0.0071 0.0107
Echinococcus multilocularis geminin 0.1547 0.483 0.4828
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0042 0.0038
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.004 0.0049 0.0072
Brugia malayi Nuclear hormone receptor family member nhr-19 0.004 0.0049 0.0117
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0048 0.0204
Schistosoma mansoni histamine h1 receptor 0.0038 0.0042 0.0061
Mycobacterium tuberculosis Probable lipase LipE 0.0182 0.0501 0.1293
Brugia malayi hypothetical protein 0.0038 0.0042 0.0093
Echinococcus granulosus neuroligin 0.0171 0.0464 0.0727
Schistosoma mansoni hypothetical protein 0.0289 0.084 0.1322
Trichomonas vaginalis CAMK family protein kinase 0.0048 0.0075 0.1138
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0011 0.0011
Schistosoma mansoni neuroligin 3 (S09 family) 0.0171 0.0464 0.0728
Brugia malayi Carboxylesterase family protein 0.0171 0.0464 0.1449
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0171 0.0464 0.046
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0095 0.0224 0.0678
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0182 0.0501 0.1293
Schistosoma mansoni neuropeptide receptor 0.0038 0.0042 0.0061
Trypanosoma brucei hypothetical protein, conserved 0.0182 0.0501 0.2566
Echinococcus multilocularis G protein coupled receptor 139 0.0038 0.0042 0.0038
Loa Loa (eye worm) hypothetical protein 0.0053 0.0089 0.0283
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0631 0.1925 1
Schistosoma mansoni jumonji domain containing protein 0.0077 0.0166 0.0257
Echinococcus granulosus neuropeptides capa receptor 0.0038 0.0042 0.006
Trichomonas vaginalis D-aminoacylase, putative 0.0182 0.0501 0.7567
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0102 0.0247 0.1242
Brugia malayi hypothetical protein 0.0466 0.14 0.4456
Loa Loa (eye worm) hypothetical protein 0.0542 0.1643 0.5255
Loa Loa (eye worm) hypothetical protein 0.0182 0.0501 0.16
Trichomonas vaginalis ap endonuclease, putative 0.0095 0.0224 0.3386
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0053 0.009 0.0138
Loa Loa (eye worm) MBCTL1 0.0053 0.0089 0.0283
Trichomonas vaginalis set domain proteins, putative 0.0233 0.0662 1
Brugia malayi AKH receptor 0.0038 0.0042 0.0093
Brugia malayi Latrophilin receptor protein 2 0.0172 0.0467 0.1459
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0096 0.0228 0.0729
Echinococcus granulosus peregrin 0.0029 0.0016 0.002
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0018 0.0025
Echinococcus granulosus tm gpcr rhodopsin 0.0038 0.0042 0.006
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0042 0.006
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0122 0.0188
Plasmodium vivax hypothetical protein, conserved 0.0182 0.0501 1
Mycobacterium ulcerans beta-lactamase 0.0182 0.0501 0.4927
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0095 0.0224 0.1164
Schistosoma mansoni terminal deoxycytidyl transferase 0.004 0.0048 0.0071
Onchocerca volvulus 0.0038 0.0042 0.0398
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0048 0.0204
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0037 0.0552
Brugia malayi TAR-binding protein 0.0063 0.0122 0.0352
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0046 0.0069 0.0104
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.0042 0.0038
Echinococcus granulosus tar DNA binding protein 0.0063 0.0122 0.0188
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0038 0.0042 0.006
Entamoeba histolytica hypothetical protein 0.0143 0.0375 1
Echinococcus multilocularis solute carrier family 5 0.0037 0.004 0.0036
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0107 0.0263 0.0628
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0172 0.0467 0.0463
Brugia malayi Tachykinin-like peptides receptor 99D 0.0038 0.0042 0.0093
Echinococcus multilocularis SAM and MBT domain containing protein 0.0046 0.0069 0.0065
Loa Loa (eye worm) hypothetical protein 0.0026 0.0004 0.001
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0028 0.0012 0.0038
Echinococcus granulosus mitogen activated protein kinase 3 0.0102 0.0247 0.0385
Echinococcus granulosus alpha 1A adrenergic receptor 0.0038 0.0042 0.006
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.004 0.0049 0.0155
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0631 0.1925 1
Onchocerca volvulus 0.0038 0.0042 0.0398
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Schistosoma mansoni cpg binding protein 0.017 0.0462 0.0726
Plasmodium falciparum thioredoxin reductase 0.0047 0.0071 0.2673
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0096 0.0228 0.0225
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0038 0.0042 0.0132
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0038 0.0042 0.0038
Echinococcus multilocularis acetylcholinesterase 0.101 0.3126 0.3124
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0038 0.0042 0.0061
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0048 0.0204
Loa Loa (eye worm) hypothetical protein 0.0182 0.0501 0.16
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0182 0.0501 0.0786
Echinococcus granulosus ubiquitin specific protease 41 0.0036 0.0037 0.0052
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0048 0.0492
Onchocerca volvulus Pyruvate kinase homolog 0.0036 0.0038 0.0341
Loa Loa (eye worm) steroid hormone receptor 0.004 0.0049 0.0155
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0042 0.0061
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0119 0.0301 0.5678
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0033 0.0026 0.0022
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0095 0.0224 0.052
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Brugia malayi beta-lactamase family protein 0.0182 0.0501 0.1568
Echinococcus multilocularis neuropeptide receptor 0.0038 0.0042 0.0038
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0038 0.0042 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0045 0.0675
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.004 0.0049 0.0072
Brugia malayi larval opioid receptor 0.0038 0.0042 0.0093
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0038 0.0042 0.0038
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0038 0.0042 0.0061
Loa Loa (eye worm) carboxylesterase 0.101 0.3126 1
Onchocerca volvulus 0.017 0.0462 0.6916
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0048 0.072
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0057 0.0864
Onchocerca volvulus 0.0038 0.0042 0.0398
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0048 0.0204
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0069 0.0104
Schistosoma mansoni thyroid hormone receptor 0.004 0.0049 0.0072
Trichomonas vaginalis pyruvate kinase, putative 0.0036 0.0038 0.0572
Echinococcus granulosus fmrfamide receptor 0.0038 0.0042 0.006
Echinococcus granulosus dna polymerase kappa 0.004 0.0048 0.007
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Echinococcus granulosus 7tm_1 domain containing protein 0.0038 0.0042 0.006
Schistosoma mansoni ap endonuclease 0.0095 0.0224 0.0349
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0299 0.087 0.452
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0096 0.0228 0.0355
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.0048 0.0724
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0038 0.012
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0042 0.0061
Echinococcus multilocularis thyroid hormone receptor alpha 0.004 0.0049 0.0045
Loa Loa (eye worm) carboxylesterase 0.0171 0.0464 0.1482
Trichomonas vaginalis chromobox protein, putative 0.007 0.0146 0.2205
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.0048 0.0114
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Echinococcus granulosus allatostatin A receptor 0.0038 0.0042 0.006
Echinococcus multilocularis chromobox protein 1 0.007 0.0146 0.0142
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.004 0.0048 0.0071
Echinococcus granulosus BC026374 protein S09 family 0.0171 0.0464 0.0727
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0048 0.0204
Schistosoma mansoni aldehyde dehydrogenase 0.025 0.0715 0.1125
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0052 0.0077
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0089 0.0204 0.1017
Echinococcus multilocularis dna polymerase kappa 0.004 0.0048 0.0044
Echinococcus granulosus carboxylesterase 5A 0.101 0.3126 0.4936
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0042 0.006
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0042 0.0061
Mycobacterium tuberculosis Conserved protein 0.0182 0.0501 0.1293
Entamoeba histolytica hypothetical protein 0.0143 0.0375 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0038 0.0042 0.0132
Loa Loa (eye worm) G-protein coupled receptor 0.0038 0.0042 0.0132
Brugia malayi neuropeptide F receptor 0.0038 0.0042 0.0093
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.004 0.0048 0.0044
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0038 0.0042 0.006
Brugia malayi jmjC domain containing protein 0.0045 0.0066 0.0173
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0057 0.064
Onchocerca volvulus 0.0037 0.004 0.0371
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0102 0.0247 0.1282
Schistosoma mansoni chromobox protein 0.007 0.0146 0.0226
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0042 0.006
Loa Loa (eye worm) hypothetical protein 0.0037 0.004 0.0126
Echinococcus multilocularis allatostatin A receptor 0.0038 0.0042 0.0038
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0038 0.0042 0.0038
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Brugia malayi hypothetical protein 0.0038 0.0042 0.0093
Echinococcus granulosus SAM and MBT domain containing protein 0.0046 0.0069 0.0103
Schistosoma mansoni pyruvate kinase 0.0036 0.0038 0.0055
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0038 0.0042 0.0038
Echinococcus multilocularis dna polymerase eta 0.004 0.0048 0.0044
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0036 0.0037 0.0052
Brugia malayi neuropeptide F receptor 0.0038 0.0042 0.0093
Schistosoma mansoni intermediate filament proteins 0.0053 0.0091 0.0138
Schistosoma mansoni kinase 0.0049 0.0079 0.012
Brugia malayi Carboxylesterase family protein 0.101 0.3126 1
Brugia malayi Pyruvate kinase, M2 isozyme 0.0036 0.0038 0.0082
Echinococcus granulosus intermediate filament protein 0.0053 0.0091 0.0138
Schistosoma mansoni amine GPCR 0.0038 0.0042 0.0061
Schistosoma mansoni aldehyde dehydrogenase 0.025 0.0715 0.1125
Echinococcus granulosus sodium:glucose cotransporter 2 0.0037 0.004 0.0057
Plasmodium vivax pyruvate kinase, putative 0.0036 0.0038 0.0454
Loa Loa (eye worm) hypothetical protein 0.0371 0.1099 0.3513
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0299 0.087 0.452
Toxoplasma gondii thioredoxin reductase 0.0047 0.0071 0.0596
Echinococcus multilocularis serotonin receptor 0.0038 0.0042 0.0038
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0042 0.0061
Echinococcus multilocularis dnaJ subfamily B 0.202 0.6331 0.6329
Brugia malayi hypothetical protein 0.0119 0.0301 0.0926
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0182 0.0501 0.4927
Loa Loa (eye worm) hypothetical protein 0.004 0.0049 0.0155
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0011 0.0167
Schistosoma mansoni retinoid-x-receptor (RXR) 0.004 0.0049 0.0072
Loa Loa (eye worm) jmjC domain-containing protein 0.0045 0.0066 0.0211
Onchocerca volvulus 0.0038 0.0042 0.0398
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.004 0.0049 0.0155
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0081 0.1228
Echinococcus granulosus ecdysone induced protein 78C 0.004 0.0049 0.0072
Brugia malayi nuclear hormone receptor 0.004 0.0049 0.0117
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0048 0.0204
Brugia malayi hypothetical protein 0.0038 0.0042 0.0093
Onchocerca volvulus 0.0171 0.0464 0.6935
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0038 0.0042 0.0061
Loa Loa (eye worm) hypothetical protein 0.0336 0.0988 0.3159
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0095 0.0224 0.1982
Mycobacterium ulcerans aldehyde dehydrogenase 0.025 0.0715 0.7212
Loa Loa (eye worm) hypothetical protein 0.004 0.0048 0.0151
Brugia malayi Nuclear hormone receptor family member nhr-49 0.004 0.0049 0.0117
Loa Loa (eye worm) beta-lactamase 0.0182 0.0501 0.16
Schistosoma mansoni DNA polymerase eta 0.004 0.0048 0.0071
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Plasmodium vivax importin-beta 2, putative 0.003 0.0018 0.0047
Brugia malayi hypothetical protein 0.0038 0.0042 0.0093
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0182 0.0501 0.1293
Trichomonas vaginalis penicillin-binding protein, putative 0.0182 0.0501 0.7567
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0038 0.0042 0.0093
Echinococcus granulosus g protein coupled receptor 0.0038 0.0042 0.006
Brugia malayi Nuclear hormone receptor family member nhr-31 0.004 0.0049 0.0117
Schistosoma mansoni hypothetical protein 0.0095 0.0224 0.0349
Loa Loa (eye worm) hypothetical protein 0.0119 0.0301 0.0961
Echinococcus multilocularis neuropeptide FF receptor 2 0.0038 0.0042 0.0038
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0182 0.0501 0.1568
Trichomonas vaginalis esterase, putative 0.0182 0.0501 0.7567
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Loa Loa (eye worm) hypothetical protein 0.0025 0.0003 0.0008
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0107 0.0263 0.4857
Onchocerca volvulus 0.0031 0.0021 0.0073
Loa Loa (eye worm) neuropeptide F receptor 0.0038 0.0042 0.0132
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0095 0.0224 0.0221
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0016 0.0049
Brugia malayi G-protein coupled receptor 0.0038 0.0042 0.0093
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0038 0.0042 0.0061
Brugia malayi Steroid receptor seven-up type 2 0.004 0.0049 0.0117
Schistosoma mansoni growth hormone secretagogue receptor 0.0038 0.0042 0.0061
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0171 0.0464 0.119
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0095 0.0224 0.1123
Echinococcus multilocularis pyruvate kinase 0.0036 0.0038 0.0034
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.004 0.0049 0.0155
Entamoeba histolytica hypothetical protein 0.0143 0.0375 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0042 0.006
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0043 0.006 0.0056
Echinococcus granulosus neuropeptide s receptor 0.1401 0.4368 0.6898
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0045 0.0675
Echinococcus multilocularis X box binding protein 1 0.0289 0.084 0.0836
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0081 0.1228
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0036 0.0037 0.0077
Echinococcus multilocularis neuropeptide Y receptor 0.0038 0.0042 0.0038
Brugia malayi PHD-finger family protein 0.0029 0.0016 0.0011
Echinococcus granulosus biogenic amine 5HT receptor 0.0038 0.0042 0.006
Leishmania major trypanothione reductase 0.0047 0.0071 0.0371
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Mycobacterium tuberculosis Probable hydrolase 0.0182 0.0501 0.1293
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0018 0.0048
Onchocerca volvulus 0.0038 0.0042 0.0398
Loa Loa (eye worm) hypothetical protein 0.004 0.0049 0.0155
Schistosoma mansoni sodium/solute symporter 0.0037 0.004 0.0058
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.004 0.0049 0.0045
Schistosoma mansoni neuropeptide f receptor 76f 0.0038 0.0042 0.0061
Echinococcus granulosus X box binding protein 1 0.0289 0.084 0.1321
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0171 0.0464 0.7008
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0247 0.3731
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0042 0.0038
Echinococcus multilocularis pyruvate kinase 0.0029 0.0014 0.001
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0459 0.1378 0.1374
Brugia malayi Bromodomain containing protein 0.0029 0.0016 0.0011
Echinococcus multilocularis fmrfamide receptor 0.0038 0.0042 0.0038
Schistosoma mansoni jumonji/arid domain-containing protein 0.0045 0.0066 0.01
Loa Loa (eye worm) acetylcholinesterase 1 0.101 0.3126 1
Trichomonas vaginalis spcc417.12 protein, putative 0.0171 0.0464 0.7008
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0038 0.0042 0.0061
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0042 0.0038
Schistosoma mansoni neuropeptide F-like receptor 0.0038 0.0042 0.0061
Loa Loa (eye worm) TYRA-2 protein 0.0038 0.0042 0.0132
Loa Loa (eye worm) latrophilin receptor protein 2 0.0172 0.0467 0.1492
Brugia malayi Nuclear hormone receptor family member nhr-1 0.004 0.0049 0.0117
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0143 0.0375 0.0371
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0045 0.0675
Echinococcus multilocularis acetylcholinesterase 0.101 0.3126 0.3124
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1164 0.3617 1
Leishmania major pyruvate kinase 0.0036 0.0038 0.0197
Echinococcus multilocularis FTZ F1 alpha 0.004 0.0049 0.0045
Echinococcus multilocularis musashi 0.0053 0.0091 0.0087
Entamoeba histolytica deoxycytidyl transferase, putative 0.004 0.0048 0.1278
Echinococcus multilocularis neuropeptide receptor 0.0038 0.0042 0.0038
Loa Loa (eye worm) hypothetical protein 0.0052 0.0088 0.0279
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0038 0.0042 0.0093
Trypanosoma brucei polo-like protein kinase 0.0096 0.0228 0.1146
Brugia malayi serine/threonine-protein kinase plk-2 0.0096 0.0228 0.0694
Entamoeba histolytica pyruvate kinase, putative 0.0025 0.0003 0.0077
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Schistosoma mansoni chromobox protein 0.007 0.0146 0.0226
Brugia malayi Dopamine receptor protein 1 0.0038 0.0042 0.0093
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0089 0.0135
Schistosoma mansoni amine GPCR 0.0038 0.0042 0.0061
Schistosoma mansoni amine GPCR 0.0038 0.0042 0.0061
Mycobacterium ulcerans esterase/lipase LipP 0.0182 0.0501 0.4927
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0097 0.0229 0.0225
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0044 0.0062 0.0094
Schistosoma mansoni biogenic amine receptor 0.0038 0.0042 0.0061
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0038 0.012
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0038 0.0042 0.0038
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0036 0.0037 0.0896
Echinococcus granulosus sodium:glucose cotransporter 0.0037 0.004 0.0057
Echinococcus granulosus sex peptide receptor 0.0038 0.0042 0.006
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0102 0.0247 0.2475
Brugia malayi RNA binding protein 0.0063 0.0122 0.0352
Echinococcus granulosus chromobox protein 1 0.007 0.0146 0.0225
Loa Loa (eye worm) hypothetical protein 0.0466 0.14 0.4478
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.005 0.0081 0.1228
Loa Loa (eye worm) intermediate filament protein 0.0053 0.0091 0.0288
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.004 0.0049 0.0072
Leishmania major hypothetical protein, conserved 0.0182 0.0501 0.2601
Trypanosoma brucei pyruvate kinase 1, putative 0.0036 0.0038 0.0151
Brugia malayi Dopamine receptor protein 2 0.0038 0.0042 0.0093
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0042 0.0038
Onchocerca volvulus 0.0046 0.0069 0.0819
Echinococcus granulosus neuropeptide Y receptor 0.0038 0.0042 0.006
Echinococcus granulosus lamin 0.0053 0.0091 0.0138
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0122 0.0119
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0038 0.0042 0.0038
Onchocerca volvulus Protein ultraspiracle homolog 0.004 0.0049 0.0511
Schistosoma mansoni Tr4/Tr2 (homologue) 0.004 0.0049 0.0072
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Brugia malayi Pre-SET motif family protein 0.0033 0.0026 0.0043
Onchocerca volvulus 0.0171 0.0464 0.6935
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0459 0.1378 0.2172
Schistosoma mansoni serine/threonine protein kinase 0.0102 0.0247 0.0385
Echinococcus granulosus importin subunit beta 1 0.003 0.0018 0.0023
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Echinococcus granulosus G protein coupled receptor 139 0.0038 0.0042 0.006
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.004 0.0048 0.0249
Trypanosoma brucei trypanothione reductase 0.0047 0.0071 0.0327
Toxoplasma gondii hypothetical protein 0.0102 0.0245 0.2458
Echinococcus multilocularis snurportin 1 0.0323 0.0946 0.0943
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0045 0.0675
Echinococcus multilocularis peregrin 0.0029 0.0016 0.0012
Onchocerca volvulus Huntingtin homolog 0.0119 0.0301 0.4414
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0038 0.0042 0.0038
Schistosoma mansoni biogenic amine receptor 0.0038 0.0042 0.0061
Trypanosoma brucei pyruvate kinase 1 0.0036 0.0038 0.0151
Echinococcus granulosus nuclear receptor 2DBD gamma 0.004 0.0049 0.0072
Onchocerca volvulus 0.0182 0.0501 0.7507
Schistosoma mansoni hypothetical protein 0.0172 0.0467 0.0733
Brugia malayi Melatonin receptor type 1A 0.0038 0.0042 0.0093
Brugia malayi CXXC zinc finger family protein 0.017 0.0462 0.1445
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0089 0.0136
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.0048 0.0204
Brugia malayi follicle stimulating hormone receptor 0.0038 0.0042 0.0093
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0089 0.0204 0.1059
Schistosoma mansoni steroid hormone receptor ad4bp 0.004 0.0049 0.0072
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.025 0.0715 0.0712
Mycobacterium ulcerans lipase LipD 0.0182 0.0501 0.4927
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0089 0.0135
Loa Loa (eye worm) hypothetical protein 0.004 0.0048 0.0152
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0119 0.0301 0.0734
Loa Loa (eye worm) hypothetical protein 0.0046 0.0069 0.0219
Onchocerca volvulus 0.0038 0.0042 0.0398
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0037 0.004 0.0257
Mycobacterium ulcerans aldehyde dehydrogenase 0.025 0.0715 0.7212
Mycobacterium ulcerans DNA polymerase IV 0.004 0.0048 0.0107
Onchocerca volvulus 0.0171 0.0464 0.6935
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0045 0.0675
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0089 0.0086
Trypanosoma cruzi pyruvate kinase 2, putative 0.0036 0.0038 0.0197
Brugia malayi Pre-SET motif family protein 0.0205 0.0573 0.1801
Echinococcus multilocularis neuropeptides capa receptor 0.0038 0.0042 0.0038
Echinococcus multilocularis dro:myosuppressin receptor 0.0038 0.0042 0.0038
Echinococcus multilocularis para nitrobenzyl esterase 0.0171 0.0464 0.046
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0026 0.0036
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0108 0.0265 0.1379
Onchocerca volvulus Huntingtin homolog 0.0119 0.0301 0.4414
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0048 0.0204
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0228 0.3452
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0459 0.1378 0.2172
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Mycobacterium tuberculosis Conserved protein 0.0182 0.0501 0.1293
Schistosoma mansoni biogenic amine (5HT) receptor 0.0038 0.0042 0.0061
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0053 0.0091 0.0288
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0029 0.0016 0.0236
Schistosoma mansoni alpha-1 adrenergic receptor 0.0038 0.0042 0.0061
Schistosoma mansoni adenoreceptor 0.0038 0.0042 0.0061
Leishmania major mitochondrial DNA polymerase beta 0.0631 0.1925 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0119 0.0301 0.0734
Loa Loa (eye worm) pyruvate kinase 0.0036 0.0038 0.012
Onchocerca volvulus 0.0182 0.0501 0.7507
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0043 0.006 0.0056
Brugia malayi Nuclear hormone receptor family member nhr-40 0.004 0.0049 0.0117
Toxoplasma gondii exonuclease III APE 0.0095 0.0224 0.2231
Trypanosoma cruzi trypanothione reductase, putative 0.0047 0.0071 0.0371
Brugia malayi ecdysteroid receptor 0.004 0.0049 0.0117
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0042 0.0038
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Echinococcus granulosus cpg binding protein 0.018 0.0493 0.0774
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0182 0.0501 0.0786
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.101 0.3126 0.4936
Leishmania major DNA polymerase eta, putative 0.004 0.0048 0.0249
Loa Loa (eye worm) hypothetical protein 0.0119 0.0301 0.0961
Schistosoma mansoni hypothetical protein 0.0038 0.0042 0.0061
Schistosoma mansoni acetylcholinesterase 0.0171 0.0464 0.0728
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0095 0.0224 0.5
Schistosoma mansoni hypothetical protein 0.0371 0.1099 0.1731
Schistosoma mansoni hypothetical protein 0.0172 0.0467 0.0733
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0038 0.0042 0.0038
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Onchocerca volvulus 0.0038 0.0042 0.0398
Trypanosoma cruzi polo-like protein kinase, putative 0.0096 0.0228 0.1187
Giardia lamblia DINP protein human, muc B family 0.004 0.0048 0.1388
Echinococcus granulosus geminin 0.1547 0.483 0.7628
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0201 0.056 0.0557
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0172 0.0467 0.0732
Schistosoma mansoni hypothetical protein 0.0143 0.0375 0.0587
Loa Loa (eye worm) hypothetical protein 0.0033 0.0026 0.0081
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Schistosoma mansoni RAR-like nuclear receptor 0.004 0.0049 0.0072
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0043 0.006 0.0089
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0107 0.0263 0.0628
Brugia malayi Serotonin receptor 0.0038 0.0042 0.0093
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0089 0.0204 0.1059
Echinococcus granulosus retinoic acid receptor rxr beta a 0.004 0.0049 0.0072
Mycobacterium tuberculosis Probable lipase LipD 0.0182 0.0501 0.1293
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0095 0.0224 0.1164
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.0025 0.0371
Schistosoma mansoni coup transcription factor 0.004 0.0049 0.0072
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0122 0.0188
Schistosoma mansoni hypothetical protein 0.03 0.0874 0.1376
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.025 0.0715 0.1892
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0018 0.0048
Trichomonas vaginalis helicase, putative 0.0039 0.0045 0.0675
Loa Loa (eye worm) glutathione reductase 0.0047 0.0071 0.0227
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0038 0.0042 0.0061
Mycobacterium tuberculosis Conserved hypothetical protein 0.004 0.0048 0.0028
Onchocerca volvulus Serine\/threonine kinase homolog 0.0096 0.0228 0.3292
Echinococcus multilocularis fmrfamide receptor 0.0038 0.0042 0.0038
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.004 0.0049 0.0072
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Echinococcus multilocularis G-protein coupled receptor, putative 0.0038 0.0042 0.0038
Loa Loa (eye worm) hypothetical protein 0.0182 0.0501 0.16
Onchocerca volvulus 0.0038 0.0042 0.0398
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0115 0.0368
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.005 0.0081 0.1228
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0122 0.0389
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0057 0.0864
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.004 0.0049 0.0117
Brugia malayi photoreceptor-specific nuclear receptor 0.004 0.0049 0.0117
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0038 0.0042 0.0132
Trypanosoma brucei protein kinase, putative 0.0102 0.0247 0.1242
Trichomonas vaginalis D-aminoacylase, putative 0.0182 0.0501 0.7567
Loa Loa (eye worm) heterochromatin protein 1 0.007 0.0146 0.0465
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0038 0.0042 0.0132
Brugia malayi MH2 domain containing protein 0.0118 0.0296 0.0909
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0011 0.0167
Schistosoma mansoni amine GPCR 0.0038 0.0042 0.0061
Brugia malayi Pyruvate kinase, muscle isozyme 0.0036 0.0038 0.0082
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0228 0.3452
Schistosoma mansoni amine GPCR 0.0038 0.0042 0.0061
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0201 0.056 0.088
Echinococcus multilocularis thioredoxin glutathione reductase 0.0047 0.0071 0.0068
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0459 0.1378 0.2172
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0299 0.087 0.4494
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0026 0.0036
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0182 0.0501 0.16
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0228 0.3452
Echinococcus granulosus beta LACTamase domain containing family member 0.0182 0.0501 0.0786
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0038 0.0042 0.0132
Schistosoma mansoni jumonji/arid domain-containing protein 0.0045 0.0066 0.01
Loa Loa (eye worm) histone methyltransferase 0.0054 0.0093 0.0295
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0048 0.0249
Echinococcus granulosus dnaJ subfamily B 0.202 0.6331 1
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0171 0.0464 0.0728
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.004 0.0049 0.0155
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Loa Loa (eye worm) hypothetical protein 0.0171 0.0464 0.1482
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.0048 0.0249
Brugia malayi mbt repeat family protein 0.0046 0.0069 0.0181
Brugia malayi exodeoxyribonuclease III family protein 0.0095 0.0224 0.0679
Loa Loa (eye worm) hypothetical protein 0.0171 0.0464 0.1482
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.004 0.0049 0.0072
Schistosoma mansoni hypothetical protein 0.0323 0.0946 0.149
Onchocerca volvulus 0.0233 0.0662 1
Schistosoma mansoni survival motor neuron protein 0.0095 0.0224 0.0349
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0205 0.0573 0.1832
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0036 0.0032
Trypanosoma cruzi hypothetical protein, conserved 0.0182 0.0501 0.2601
Schistosoma mansoni hypothetical protein 0.0038 0.0042 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0037 0.0552
Schistosoma mansoni inositol transporter 0.0037 0.004 0.0058
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0107 0.0263 0.0628
Brugia malayi Nuclear hormone receptor family member nhr-25 0.004 0.0049 0.0117
Onchocerca volvulus 0.0038 0.0042 0.0398
Onchocerca volvulus 0.0038 0.0042 0.0398
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0036 0.0037 0.0552
Loa Loa (eye worm) neuropeptide F receptor 0.0038 0.0042 0.0132
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0048 0.072
Echinococcus multilocularis BC026374 protein (S09 family) 0.0171 0.0464 0.046
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0038 0.0042 0.0061
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Echinococcus granulosus hypothetical protein 0.0038 0.0042 0.006
Toxoplasma gondii ABC1 family protein 0.0182 0.0501 0.5195
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0038 0.0042 0.006
Brugia malayi hypothetical protein 0.0038 0.0042 0.0093
Brugia malayi steroid hormone receptor 0.004 0.0049 0.0117
Brugia malayi Carboxylesterase family protein 0.0171 0.0464 0.1449
Loa Loa (eye worm) hypothetical protein 0.101 0.3126 1
Brugia malayi Dopamine receptor 0.0038 0.0042 0.0093
Echinococcus multilocularis high affinity choline transporter 1 0.0336 0.0988 0.0985
Schistosoma mansoni hypothetical protein 0.1547 0.483 0.7628
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.025 0.0715 0.3716
Loa Loa (eye worm) melatonin receptor type 1A 0.0038 0.0042 0.0132
Loa Loa (eye worm) CXXC zinc finger family protein 0.017 0.0462 0.1478
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Echinococcus granulosus dro:myosuppressin receptor 0.0038 0.0042 0.006
Loa Loa (eye worm) hypothetical protein 0.004 0.0049 0.0155
Loa Loa (eye worm) hypothetical protein 0.101 0.3126 1
Mycobacterium tuberculosis Carboxylesterase LipT 0.0171 0.0464 0.119
Loa Loa (eye worm) hypothetical protein 0.004 0.0049 0.0155
Echinococcus granulosus sodium:myo inositol cotransporter 0.0037 0.004 0.0057
Echinococcus multilocularis neuropeptide receptor A26 0.1401 0.4368 0.4366
Echinococcus granulosus g-protein coupled receptor 0.0038 0.0042 0.006
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Brugia malayi chromobox protein homolog 3 0.004 0.0048 0.0113
Schistosoma mansoni opsin-like receptor 0.0038 0.0042 0.0061
Loa Loa (eye worm) hypothetical protein 0.0171 0.0464 0.1482
Mycobacterium ulcerans aldehyde dehydrogenase 0.025 0.0715 0.7212
Onchocerca volvulus 0.0044 0.0062 0.072
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0054 0.0093 0.0141
Echinococcus granulosus mitogen activated protein kinase 0.0102 0.0247 0.0385
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Onchocerca volvulus 0.0182 0.0501 0.7507
Brugia malayi hypothetical protein 0.0143 0.0375 0.1164
Schistosoma mansoni hypothetical protein 0.202 0.6331 1
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0122 0.0188
Echinococcus granulosus neuropeptide FF receptor 2 0.0038 0.0042 0.006
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0102 0.0247 0.0788
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0038 0.0042 0.0038
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0038 0.0042 0.0093
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0095 0.0224 0.5977
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0122 0.0188
Brugia malayi Serotonin receptor 0.0038 0.0042 0.0093
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0171 0.0464 0.119
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0095 0.0224 0.1164
Echinococcus multilocularis mitogen activated protein kinase 0.0102 0.0247 0.0243
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0038 0.0042 0.0093
Echinococcus multilocularis GPCR, family 2 0.0172 0.0467 0.0463
Trichomonas vaginalis CMGC family protein kinase 0.0102 0.0247 0.3731
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0026 0.0022
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0038 0.0042 0.006
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Echinococcus multilocularis lamin dm0 0.0053 0.0091 0.0087
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0036 0.0037 0.0033
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0542 0.1643 0.5255
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.004 0.0049 0.0045
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.004 0.0048 0.0152
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0182 0.0501 0.1293
Loa Loa (eye worm) hypothetical protein 0.0038 0.0042 0.0132
Echinococcus granulosus rhodopsin orphan GPCR 0.0038 0.0042 0.006
Trichomonas vaginalis penicillin-binding protein, putative 0.0182 0.0501 0.7567
Echinococcus multilocularis g protein coupled receptor 0.0038 0.0042 0.0038
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0095 0.0224 0.9013
Schistosoma mansoni cpg binding protein 0.018 0.0493 0.0775
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0038 0.0042 0.0061
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.0069 0.0104
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.025 0.0715 0.1125
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0047 0.0071 0.0094
Echinococcus multilocularis rhodopsin orphan GPCR 0.0038 0.0042 0.0038
Trichomonas vaginalis D-aminoacylase, putative 0.0182 0.0501 0.7567
Brugia malayi Nuclear hormone receptor-like 1 0.004 0.0049 0.0117
Brugia malayi hypothetical protein 0.0038 0.0042 0.0093
Loa Loa (eye worm) hypothetical protein 0.0182 0.0501 0.16
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0045 0.0675
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0038 0.0042 0.0061
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.0048 0.0204
Echinococcus granulosus survival motor neuron protein 1 0.0466 0.14 0.2207
Onchocerca volvulus 0.0171 0.0464 0.6935
Schistosoma mansoni hypothetical protein 0.0029 0.0016 0.002
Mycobacterium tuberculosis Probable dehydrogenase 0.0107 0.0263 0.0628
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0228 0.3452
Brugia malayi Nuclear hormone receptor family member nhr-41 0.004 0.0049 0.0117
Loa Loa (eye worm) hypothetical protein 0.004 0.0049 0.0155
Trichomonas vaginalis CAMK family protein kinase 0.0096 0.0228 0.3452
Echinococcus multilocularis polycomb protein SCMH1 0.0046 0.0069 0.0065
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0631 0.1925 1
Echinococcus multilocularis neuroligin 0.0171 0.0464 0.046

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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