Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | RNA binding protein | 0.0066 | 0.6123 | 0.6123 |
Echinococcus multilocularis | transient receptor potential gamma protein | 0.0102 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.6123 | 0.6123 |
Brugia malayi | Transient-receptor-potential like protein | 0.0038 | 0.2989 | 0.4882 |
Echinococcus granulosus | TRP transient receptor potential channel | 0.0038 | 0.2989 | 0.2989 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0066 | 0.6123 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.6123 | 0.6123 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0011 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.6123 | 0.6123 |
Brugia malayi | RNA binding protein | 0.0066 | 0.6123 | 1 |
Brugia malayi | TAR-binding protein | 0.0066 | 0.6123 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.6123 | 0.6123 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.2989 | 0.2989 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.2617 | 0.2617 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0011 | 0 | 0.5 |
Echinococcus granulosus | tar DNA binding protein | 0.0066 | 0.6123 | 0.6123 |
Loa Loa (eye worm) | TAR-binding protein | 0.0066 | 0.6123 | 0.6123 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 1 | 1 |
Schistosoma mansoni | transient receptor potential channel | 0.0067 | 0.6221 | 0.6221 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0067 | 0.6221 | 0.6221 |
Echinococcus granulosus | transient receptor potential ion channel A | 0.0098 | 0.9628 | 0.9628 |
Schistosoma mansoni | transient receptor potential channel | 0.0067 | 0.6221 | 0.6221 |
Schistosoma mansoni | transient receptor potential channel | 0.0102 | 1 | 1 |
Echinococcus multilocularis | transient receptor potential ion channel A | 0.0098 | 0.9628 | 0.9628 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.6123 | 0.6123 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0067 | 0.6221 | 0.6221 |
Schistosoma mansoni | transient receptor potential channel 4 | 0.0102 | 1 | 1 |
Echinococcus multilocularis | TRP (transient receptor potential) channel | 0.0038 | 0.2989 | 0.2989 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0067 | 0.6221 | 0.6221 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0011 | 0 | 0.5 |
Onchocerca volvulus | 0.0011 | 0 | 0.5 | |
Echinococcus multilocularis | tar DNA binding protein | 0.0066 | 0.6123 | 0.6123 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0067 | 0.6221 | 0.6221 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.5849 | 0.5849 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0066 | 0.6123 | 0.6123 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.