Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | nucleoside phosphorylase-like protein | 0.0088 | 0.1889 | 1 |
Treponema pallidum | pfs protein (pfs) | 0.0088 | 0.1889 | 0.5 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0426 | 1 | 1 |
Toxoplasma gondii | phosphorylase family protein | 0.0088 | 0.1889 | 1 |
Plasmodium falciparum | purine nucleoside phosphorylase | 0.0088 | 0.1889 | 1 |
Giardia lamblia | 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase | 0.0088 | 0.1889 | 0.1855 |
Trypanosoma brucei | methylthioadenosine phosphorylase, putative | 0.0088 | 0.1889 | 1 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0426 | 1 | 1 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0426 | 1 | 1 |
Schistosoma mansoni | purine nucleoside phosphorylase | 0.0426 | 1 | 1 |
Trichomonas vaginalis | purine nucleoside phosphorylase I, putative | 0.0426 | 1 | 1 |
Onchocerca volvulus | Purine nucleoside phosphorylase homolog | 0.0426 | 1 | 0.5 |
Mycobacterium tuberculosis | Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP) | 0.0426 | 1 | 1 |
Trypanosoma cruzi | methylthioadenosine phosphorylase, putative | 0.0088 | 0.1889 | 1 |
Schistosoma mansoni | ATP-binding cassette sub-family g2 (white protein) (abcg2) | 0.0011 | 0.0045 | 0.0045 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0338 | 0.7882 | 0.7872 |
Entamoeba histolytica | purine nucleoside phosphorylase, putative | 0.0088 | 0.1889 | 1 |
Schistosoma mansoni | uridine phosphorylase | 0.0088 | 0.1889 | 0.1889 |
Loa Loa (eye worm) | uridine phosphorylase | 0.0088 | 0.1889 | 0.2394 |
Toxoplasma gondii | phosphorylase family protein | 0.0088 | 0.1889 | 1 |
Mycobacterium ulcerans | 5'-methylthioadenosine phosphorylase | 0.0088 | 0.1889 | 0.1852 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0426 | 1 | 1 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0426 | 1 | 1 |
Schistosoma mansoni | ABC transporter | 0.001 | 0.0003 | 0.0003 |
Mycobacterium leprae | Probable purine nucleoside phosphorylase DeoD (INOSINE PHOSPHORYLASE) (PNP) | 0.0426 | 1 | 1 |
Treponema pallidum | uridine phosphorylase (udp) | 0.0088 | 0.1889 | 0.5 |
Schistosoma mansoni | methylthioadenosine phosphorylase | 0.0088 | 0.1889 | 0.1889 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0426 | 1 | 1 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0426 | 1 | 1 |
Echinococcus granulosus | methylthioadenosine phosphorylase | 0.0088 | 0.1889 | 0.1852 |
Entamoeba histolytica | purine nucleoside phosphorylase, putative | 0.0088 | 0.1889 | 1 |
Plasmodium vivax | purine nucleoside phosphorylase, putative | 0.0088 | 0.1889 | 1 |
Giardia lamblia | UPL-1 | 0.0088 | 0.1889 | 0.1855 |
Mycobacterium tuberculosis | Hypothetical protein | 0.0088 | 0.1889 | 0.1889 |
Entamoeba histolytica | purine nucleoside phosphorylase, putative | 0.0088 | 0.1889 | 1 |
Mycobacterium ulcerans | purine nucleoside phosphorylase | 0.0426 | 1 | 1 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0426 | 1 | 1 |
Schistosoma mansoni | purine nucleoside phosphorylase | 0.0426 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0338 | 0.7882 | 1 |
Giardia lamblia | Purine nucleoside phosphorylase lateral transfer candidate | 0.0426 | 1 | 1 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0426 | 1 | 1 |
Schistosoma mansoni | methylthioadenosine phosphorylase | 0.0088 | 0.1889 | 0.1889 |
Trypanosoma cruzi | nucleoside phosphorylase, putative | 0.0088 | 0.1889 | 1 |
Entamoeba histolytica | MTA/SAH nucleosidase, putative | 0.0088 | 0.1889 | 1 |
Entamoeba histolytica | purine nucleoside phosphorylase, putative | 0.0088 | 0.1889 | 1 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0426 | 1 | 1 |
Leishmania major | methylthioadenosine phosphorylase, putative | 0.0088 | 0.1889 | 1 |
Echinococcus multilocularis | methylthioadenosine phosphorylase | 0.0088 | 0.1889 | 0.1852 |
Loa Loa (eye worm) | S-methyl-5'-thioadenosine phosphorylase MTAP | 0.0088 | 0.1889 | 0.2394 |
Trypanosoma cruzi | methylthioadenosine phosphorylase, putative | 0.0088 | 0.1889 | 1 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0426 | 1 | 1 |
Echinococcus granulosus | uridine phosphorylase 1 | 0.0088 | 0.1889 | 0.1852 |
Brugia malayi | uridine phosphorylase family protein | 0.0088 | 0.1889 | 0.1886 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0338 | 0.7882 | 0.7872 |
Echinococcus granulosus | purine nucleoside phosphorylase | 0.0426 | 1 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0088 | 0.1889 | 0.1889 |
Entamoeba histolytica | hypothetical protein | 0.0088 | 0.1889 | 1 |
Trypanosoma cruzi | nucleoside phosphorylase, putative | 0.0088 | 0.1889 | 1 |
Chlamydia trachomatis | AMP nucleosidase | 0.0088 | 0.1889 | 0.5 |
Toxoplasma gondii | Purine nucleoside phosphorylase | 0.0088 | 0.1889 | 1 |
Giardia lamblia | 5-methylthioadenosine nucleosidase, S-adenosylhomocysteine nucleosidase | 0.0088 | 0.1889 | 0.1855 |
Mycobacterium ulcerans | bifunctional Mta/Sah nucleosidase Mtn | 0.0088 | 0.1889 | 0.1852 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0426 | 1 | 1 |
Treponema pallidum | purine nucleoside phosphorylase (deoD) | 0.0088 | 0.1889 | 0.5 |
Schistosoma mansoni | methylthioadenosine phosphorylase | 0.0088 | 0.1889 | 0.1889 |
Echinococcus granulosus | inosine guanosine and xanthosine phosphorylase | 0.0338 | 0.7882 | 0.7872 |
Brugia malayi | MTAP | 0.0088 | 0.1889 | 0.1886 |
Schistosoma mansoni | uridine phosphorylase | 0.0088 | 0.1889 | 0.1889 |
Echinococcus multilocularis | purine nucleoside phosphorylase | 0.0426 | 1 | 1 |
Trypanosoma brucei | uridine phosphorylase | 0.0088 | 0.1889 | 1 |
Trypanosoma cruzi | nucleoside phosphorylase, putative | 0.0088 | 0.1889 | 1 |
Echinococcus multilocularis | uridine phosphorylase 1 | 0.0088 | 0.1889 | 0.1852 |
Entamoeba histolytica | purine nucleoside phosphorylase, putative | 0.0088 | 0.1889 | 1 |
Mycobacterium tuberculosis | Probable bifunctional MTA/SAH nucleosidase Mtn: 5'-methylthioadenosine nucleosidase (methylthioadenosine methylthioribohydrolase | 0.0088 | 0.1889 | 0.1889 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.