Detailed information for compound 625445

Basic information

Technical information
  • TDR Targets ID: 625445
  • Name: 1-[2-fluoro-5-[(3-methylphenyl)carbamoyl]phen yl]sulfonylpiperidine-4-carboxamide
  • MW: 419.47 | Formula: C20H22FN3O4S
  • H donors: 2 H acceptors: 4 LogP: 1.74 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: NC(=O)C1CCN(CC1)S(=O)(=O)c1cc(ccc1F)C(=O)Nc1cccc(c1)C
  • InChi: 1S/C20H22FN3O4S/c1-13-3-2-4-16(11-13)23-20(26)15-5-6-17(21)18(12-15)29(27,28)24-9-7-14(8-10-24)19(22)25/h2-6,11-12,14H,7-10H2,1H3,(H2,22,25)(H,23,26)
  • InChiKey: BZPCHZMIKBQRBH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-[2-fluoro-5-[[(3-methylphenyl)amino]-oxomethyl]phenyl]sulfonyl-4-piperidinecarboxamide
  • 1-[2-fluoro-5-[(3-methylphenyl)carbamoyl]phenyl]sulfonylisonipecotamide
  • EU-0096212
  • ZINC03022281
  • Oprea1_075209

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0132 0.0295
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.011 0.0384 0.0858
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0021 0.001 0.0077
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0084 0.0273 0.0312
Loa Loa (eye worm) transcription factor SMAD2 0.0125 0.0445 0.0996
Echinococcus multilocularis cpg binding protein 0.0036 0.0072 0.0072
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0024 0.0118
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.001 0.0077
Entamoeba histolytica hypothetical protein 0.0021 0.001 0.0038
Mycobacterium ulcerans dehydrogenase 0.0029 0.0043 0.0178
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0447 0.1993
Brugia malayi topoisomerase 0.0031 0.0052 0.0116
Echinococcus multilocularis ecdysone induced protein 78C 0.0084 0.0273 0.0273
Loa Loa (eye worm) hypothetical protein 0.0039 0.0086 0.0193
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0084 0.0273 0.0312
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0021 0.001 0.0011
Trypanosoma cruzi oxidoreductase-like protein, putative 0.002 0.0005 0.0043
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0137 0.0498 0.0972
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0129 0.0148
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.001 0.0013
Plasmodium vivax hypothetical protein, conserved 0.0111 0.0386 0.307
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0005 0.0012
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0075 0.0086
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.001 0.0077
Mycobacterium ulcerans short-chain dehydrogenase 0.002 0.0005 0.0011
Echinococcus multilocularis expressed protein 0.0021 0.001 0.001
Trichomonas vaginalis maltase-glucoamylase, putative 0.0028 0.0039 0.0071
Brugia malayi Bromodomain containing protein 0.0079 0.0252 0.0564
Trypanosoma brucei oxidoreductase-like protein 0.002 0.0005 0.0043
Echinococcus multilocularis peptidase Clp (S14 family) 0.005 0.0132 0.0132
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0005 0.0011
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.001 0.0022
Onchocerca volvulus Protein ultraspiracle homolog 0.0084 0.0273 0.0525
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0111 0.0386 0.0864
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.001 0.0077
Loa Loa (eye worm) hypothetical protein 0.0103 0.0352 0.0788
Loa Loa (eye worm) hypothetical protein 0.0034 0.0065 0.0145
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0029 0.0043 0.0043
Brugia malayi RNA recognition motif domain containing protein 0.0657 0.269 0.6017
Echinococcus multilocularis ubiquitin specific protease 41 0.0196 0.0748 0.0748
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Loa Loa (eye worm) hypothetical protein 0.0053 0.0143 0.032
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0043 0.0101 0.0225
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.002 0.0005 0.0043
Schistosoma mansoni tar DNA-binding protein 0.0657 0.269 0.3079
Trichomonas vaginalis conserved hypothetical protein 0.0196 0.0748 0.1462
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0005 0.0011
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0199 0.0758 0.0868
Schistosoma mansoni hypothetical protein 0.0114 0.0399 0.0457
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0003 0.0024
Loa Loa (eye worm) hypothetical protein 0.0111 0.0386 0.0864
Loa Loa (eye worm) hypothetical protein 0.0079 0.0251 0.0562
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0005 0.0043
Schistosoma mansoni lamin 0.008 0.0258 0.0295
Trypanosoma brucei metacaspase MCA3 0.0137 0.0498 0.396
Echinococcus multilocularis lysosomal alpha glucosidase 0.0344 0.137 0.137
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Brugia malayi nuclear hormone receptor 0.0084 0.0273 0.061
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0196 0.0748 0.0748
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0003 0.0003
Mycobacterium ulcerans ferredoxin reductase 0.0029 0.0043 0.0178
Leishmania major short chain dehydrogenase, putative 0.002 0.0005 0.0043
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0021 0.001 0.0011
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.002 0.0005 0.0043
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 23 0.0021 0.001 0.0011
Echinococcus granulosus neutral alpha glucosidase AB 0.0076 0.0241 0.0276
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.011 0.0384 0.3048
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0026 0.0031 0.0078
Onchocerca volvulus 0.008 0.0258 0.0495
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.002 0.0005 0.0043
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0029 0.0043 0.0339
Schistosoma mansoni nuclear receptor 0.0039 0.0086 0.0099
Echinococcus multilocularis caspase 0.0363 0.145 0.145
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0039 0.0083 0.0083
Mycobacterium tuberculosis Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1 0.002 0.0005 0.0007
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0005 0.0043
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0029 0.0043 0.0339
Echinococcus granulosus lamin 0.008 0.0258 0.0295
Brugia malayi jmjC domain containing protein 0.0075 0.0237 0.0531
Leishmania major dihydrolipoamide dehydrogenase, putative 0.011 0.0384 0.3048
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Trypanosoma cruzi 3-ketoacyl-CoA reductase, putative 0.002 0.0005 0.0043
Schistosoma mansoni short chain dehydrogenase 0.002 0.0005 0.0006
Mycobacterium ulcerans beta-lactamase 0.0111 0.0386 0.1721
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0031 0.0052 0.0096
Schistosoma mansoni ubiquitin-specific peptidase 7 (C19 family) 0.0021 0.001 0.0011
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0039 0.0086 0.0086
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0039 0.0086 0.0099
Echinococcus granulosus PHD finger protein rhinoceros 0.0059 0.0169 0.0193
Brugia malayi jmjC domain containing protein 0.0193 0.0736 0.1646
Entamoeba histolytica short chain dehydrogenase family protein 0.002 0.0005 0.0013
Schistosoma mansoni thyroid hormone receptor 0.0084 0.0273 0.0312
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0003 0.0024
Mycobacterium ulcerans ketoacyl reductase 0.002 0.0005 0.0011
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0099 0.0099
Brugia malayi PHD-finger family protein 0.0023 0.0017 0.0038
Brugia malayi mbt repeat family protein 0.0047 0.0116 0.0259
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0724 0.2974 0.8971
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0005 0.0011
Treponema pallidum DNA ligase (lig) 0.0031 0.0052 0.0589
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0003 0.0024
Echinococcus multilocularis dna polymerase eta 0.002 0.0003 0.0003
Schistosoma mansoni steroid dehydrogenase 0.002 0.0005 0.0006
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0805 0.3315 1
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.001 0.0077
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0244 0.5901
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0029 0.0043 0.0096
Echinococcus multilocularis musashi 0.008 0.0258 0.0258
Plasmodium falciparum ataxin-2 like protein, putative 0.0103 0.0352 0.2799
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0005 0.0043
Echinococcus granulosus dna polymerase kappa 0.002 0.0003 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C19, putative 0.0021 0.001 0.0077
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0244 0.5901
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0077 0.0244 0.1937
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0724 0.2974 0.8971
Treponema pallidum exodeoxyribonuclease (exoA) 0.0077 0.0244 0.6051
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0184 0.1464
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0084 0.0273 0.0312
Schistosoma mansoni myelin transcription factor 1 myt1 0.0053 0.0143 0.0164
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0005 0.0005
Echinococcus multilocularis Niemann Pick C1 protein 0.0141 0.0516 0.0516
Trichomonas vaginalis alpha-glucosidase, putative 0.0076 0.0241 0.0468
Schistosoma mansoni short chain dehydrogenase 0.002 0.0005 0.0006
Echinococcus granulosus hypothetical protein 0.002 0.0005 0.0006
Echinococcus granulosus glutamate synthase 0.0029 0.0043 0.0049
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0173 0.0649 0.0649
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0005 0.0005
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0005 0.0007
Schistosoma mansoni hypothetical protein 0.0041 0.0092 0.0105
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0044 0.0106 0.0106
Loa Loa (eye worm) hypothetical protein 0.0031 0.0052 0.0116
Onchocerca volvulus 0.005 0.0128 0.0242
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.044 0.1776 1
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0005 0.0005
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0039 0.0086 0.0086
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.0324 0.0324
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0051 0.0134 0.1066
Schistosoma mansoni disulfide oxidoreductase 0.0029 0.0043 0.0049
Giardia lamblia Thioredoxin reductase 0.0029 0.0043 0.0533
Echinococcus granulosus nuclear receptor nhr 48 0.0039 0.0086 0.0099
Loa Loa (eye worm) hypothetical protein 0.0073 0.0226 0.0505
Schistosoma mansoni short chain dehydrogenase 0.002 0.0005 0.0006
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.002 0.0005 0.0007
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0324 0.0371
Schistosoma mansoni steroid dehydrogenase 0.002 0.0005 0.0006
Mycobacterium tuberculosis Possible iron-regulated short-chain dehydrogenase/reductase 0.002 0.0005 0.0007
Brugia malayi Nuclear hormone receptor E75 0.0039 0.0086 0.0193
Schistosoma mansoni caspase-3 (C14 family) 0.0363 0.145 0.1659
Schistosoma mansoni ubiquitin-specific peptidase 48 (C19 family) 0.0021 0.001 0.0011
Echinococcus granulosus 3 ketodihydrosphingosine reductase 0.002 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0084 0.0273 0.061
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase family 2, putative 0.0021 0.001 0.0077
Brugia malayi tailless protein 0.0039 0.0086 0.0193
Echinococcus multilocularis geminin 0.1219 0.5065 0.5065
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0039 0.0086 0.0159
Schistosoma mansoni ubiquitin-specific peptidase 42 (C19 family) 0.0021 0.001 0.0011
Entamoeba histolytica hypothetical protein, conserved 0.002 0.0005 0.0013
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0005 0.0012
Mycobacterium tuberculosis Conserved protein 0.0111 0.0386 0.1158
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0128 0.1014
Schistosoma mansoni short chain dehydrogenase 0.002 0.0005 0.0006
Giardia lamblia Short-chain dehydrogenase, putative 0.002 0.0005 0.0032
Mycobacterium ulcerans short-chain dehydrogenase 0.002 0.0005 0.0011
Trichomonas vaginalis alpha-glucosidase, putative 0.0076 0.0241 0.0468
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 20 0.0021 0.001 0.001
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0129 0.0148
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0005 0.0043
Echinococcus granulosus Dehydrogenase:reductase SDR family 0.002 0.0005 0.0006
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.001 0.0077
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Echinococcus granulosus polycomb protein SCMH1 0.0047 0.0116 0.0133
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0021 0.001 0.0038
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.001 0.0038
Schistosoma mansoni retinoic acid receptor RXR 0.0084 0.0273 0.0312
Brugia malayi TAR-binding protein 0.0657 0.269 0.6017
Mycobacterium ulcerans hypothetical protein 0.0111 0.0386 0.1721
Loa Loa (eye worm) hypothetical protein 0.0039 0.0086 0.0193
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0077 0.0244 0.1942
Brugia malayi hypothetical protein 0.0039 0.0086 0.0193
Loa Loa (eye worm) hypothetical protein 0.0028 0.0039 0.0088
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0077 0.0244 0.1942
Echinococcus multilocularis muscleblind protein 1 0.015 0.0553 0.0553
Leishmania major hypothetical protein, conserved 0.0029 0.0043 0.0339
Brugia malayi beta-lactamase family protein 0.0111 0.0386 0.0864
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0244 0.1937
Loa Loa (eye worm) nuclear hormone receptor 0.0039 0.0086 0.0193
Plasmodium falciparum metacaspase-like protein 0.0137 0.0498 0.396
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.001 0.0013
Leishmania major hypothetical protein, conserved 0.002 0.0005 0.0043
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.001 0.0022
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0029 0.0043 0.0078
Loa Loa (eye worm) hypothetical protein 0.0039 0.0086 0.0193
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0044 0.0106 0.0122
Mycobacterium tuberculosis Probable dehydrogenase 0.002 0.0005 0.0007
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.011 0.0384 0.1708
Brugia malayi dehydrogenases, short chain protein 9 0.002 0.0005 0.0012
Loa Loa (eye worm) hypothetical protein 0.0233 0.0904 0.2022
Onchocerca volvulus 0.0032 0.0056 0.0099
Trypanosoma cruzi hypothetical protein, conserved 0.0111 0.0386 0.307
Trichomonas vaginalis ap endonuclease, putative 0.0077 0.0244 0.0474
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0005 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0084 0.0273 0.061
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.002 0.0005 0.0011
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Schistosoma mansoni tar DNA-binding protein 0.0657 0.269 0.3079
Schistosoma mansoni ubiquitin-specific peptidase 30 (C19 family) 0.0021 0.001 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0003 0.0024
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.0324 0.0371
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0059 0.0169 0.0193
Loa Loa (eye worm) hypothetical protein 0.044 0.1776 0.3972
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.001 0.0077
Toxoplasma gondii ubiquitin-specific protease USP4 0.0021 0.001 0.0077
Echinococcus multilocularis caspase 3 0.0225 0.0871 0.0871
Brugia malayi Dehydrogenases, short chain protein 2 0.002 0.0005 0.0012
Echinococcus granulosus caspase 8 0.0137 0.0498 0.057
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0003 0.0024
Loa Loa (eye worm) mbt repeat family protein 0.0047 0.0116 0.0259
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Leishmania major glycosyl hydrolase-like protein 0.0028 0.0039 0.0313
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0137 0.0498 0.057
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0132 0.0295
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0029 0.0043 0.0339
Schistosoma mansoni tar DNA-binding protein 0.0657 0.269 0.3079
Schistosoma mansoni calpain-7 (C02 family) 0.0021 0.001 0.0011
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.014 0.0512 0.407
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0077 0.0244 0.1942
Plasmodium falciparum steroid dehydrogenase, putative 0.002 0.0005 0.0043
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.0386 0.0752
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0005 0.0005
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0024 0.0094
Schistosoma mansoni caspase-7 (C14 family) 0.0363 0.145 0.1659
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.0021 0.001 0.0038
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0029 0.0043 0.0224
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0021 0.001 0.001
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0003 0.0024
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 36 0.0021 0.001 0.0011
Giardia lamblia Glutamate synthase 0.0029 0.0043 0.0533
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0009 0.0074
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0196 0.0748 0.0748
Echinococcus granulosus muscleblind protein 0.015 0.0553 0.0633
Trichomonas vaginalis conserved hypothetical protein 0.0137 0.0498 0.0972
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Trichomonas vaginalis sucrase-isomaltase, putative 0.0076 0.0241 0.0468
Trichomonas vaginalis steroid dehydrogenase, putative 0.002 0.0005 0.0005
Echinococcus granulosus hypothetical protein 0.002 0.0005 0.0006
Schistosoma mansoni nuclear hormone receptor 0.0039 0.0086 0.0099
Loa Loa (eye worm) hypothetical protein 0.0039 0.0086 0.0193
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.001 0.0013
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.011 0.0384 0.3048
Trichomonas vaginalis ubiquitin specific protease, putative 0.0021 0.001 0.0013
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.0021 0.001 0.001
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0075 0.0075
Loa Loa (eye worm) hypothetical protein 0.0052 0.0139 0.0311
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0005 0.0011
Mycobacterium ulcerans esterase/lipase LipP 0.0111 0.0386 0.1721
Plasmodium falciparum phd finger protein, putative 0.0059 0.0169 0.1341
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Leishmania major hypothetical protein, conserved 0.002 0.0005 0.0043
Trypanosoma cruzi PAB1-binding protein , putative 0.0103 0.0352 0.2799
Trypanosoma cruzi beta-ketoacyl-ACP reductase 2, putative 0.002 0.0005 0.0043
Echinococcus granulosus zinc finger protein 0.0022 0.0012 0.0014
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0029 0.0043 0.0339
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.011 0.0384 0.3048
Brugia malayi hypothetical protein 0.0233 0.0904 0.2022
Loa Loa (eye worm) hypothetical protein 0.0039 0.0086 0.0193
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.001 0.0077
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.019 0.0723 0.1617
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Toxoplasma gondii oxidoreductase, putative 0.002 0.0005 0.0043
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.005 0.0132 0.039
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.001 0.0022
Mycobacterium tuberculosis Decaprenylphosphoryl-D-2-keto erythro pentose reductase 0.002 0.0005 0.0007
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0003 0.0024
Toxoplasma gondii NADPH-glutathione reductase 0.011 0.0384 0.3048
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0096 0.0324 0.0726
Onchocerca volvulus Huntingtin homolog 0.0122 0.0434 0.0842
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0084 0.0273 0.061
Loa Loa (eye worm) hypothetical protein 0.0044 0.0106 0.0237
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0029 0.0043 0.0049
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0029 0.0043 0.0339
Leishmania major cathepsin L-like protease 0.0063 0.0184 0.1464
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.011 0.0384 0.3048
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.002 0.0005 0.0007
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.001 0.0077
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0129 0.0248
Schistosoma mansoni jumonji domain containing protein 0.0154 0.0568 0.065
Loa Loa (eye worm) nuclear receptor NHR-67 0.0039 0.0086 0.0193
Echinococcus granulosus Nuclear hormone receptor HR96 0.0039 0.0086 0.0099
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0005 0.0005
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0129 0.1026
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0129 0.1026
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0196 0.0748 1
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0029 0.0043 0.0339
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0029 0.0043 0.0339
Schistosoma mansoni hypothetical protein 0.0021 0.001 0.0011
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0505 0.2052 0.4591
Trichomonas vaginalis ubiquitin specific protease, putative 0.0021 0.001 0.0013
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0196 0.0748 0.5943
Mycobacterium ulcerans hypothetical protein 0.0029 0.0043 0.0178
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.001 0.0077
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.001 0.0022
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.001 0.0013
Schistosoma mansoni ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold 0.0021 0.001 0.0011
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.001 0.0077
Schistosoma mansoni cpg binding protein 0.0032 0.0056 0.0064
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.001 0.0077
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Mycobacterium tuberculosis Possible ketoacyl reductase 0.002 0.0005 0.0007
Giardia lamblia Reductase, putative 0.002 0.0005 0.0032
Echinococcus multilocularis retinol dehydrogenase 13 0.002 0.0005 0.0005
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Toxoplasma gondii PHD-finger domain-containing protein 0.0059 0.0169 0.1341
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Brugia malayi conserved hypotetical protein 0.0039 0.0086 0.0193
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0173 0.0649 0.0743
Brugia malayi Retinol dehydrogenase 12 0.002 0.0005 0.0012
Echinococcus granulosus dna polymerase eta 0.002 0.0003 0.0003
Schistosoma mansoni sulfide quinone reductase 0.0029 0.0043 0.0049
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0111 0.0386 0.0864
Loa Loa (eye worm) beta-lactamase 0.0111 0.0386 0.0864
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0155 0.0575 0.0658
Echinococcus granulosus apoptotic protease activating factor 1 0.0128 0.0459 0.0525
Brugia malayi Steroid receptor seven-up type 2 0.0084 0.0273 0.061
Echinococcus granulosus carbonyl reductase 1 0.002 0.0005 0.0006
Mycobacterium tuberculosis Probable reductase 0.0724 0.2974 0.8971
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0005 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0241 0.1917
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0657 0.269 0.6017
Schistosoma mansoni calpain-7 (C02 family) 0.0021 0.001 0.0011
Brugia malayi CHE-14 protein 0.0042 0.0099 0.0221
Plasmodium falciparum glutathione reductase 0.011 0.0384 0.3048
Schistosoma mansoni glutamate synthase 0.0029 0.0043 0.0049
Echinococcus granulosus retinol dehydrogenase 11 0.002 0.0005 0.0006
Trichomonas vaginalis ubiquitin specific protease, putative 0.0021 0.001 0.0013
Echinococcus multilocularis estradiol 17 beta dehydrogenase 12 0.002 0.0005 0.0005
Echinococcus multilocularis lamin dm0 0.008 0.0258 0.0258
Onchocerca volvulus 0.0111 0.0386 0.0748
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0005 0.0011
Schistosoma mansoni steroid dehydrogenase 0.002 0.0005 0.0006
Echinococcus granulosus neuropeptide receptor A26 0.0939 0.3881 0.4441
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.001 0.0077
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0096 0.076
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.0386 0.0752
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.001 0.0077
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0024 0.0063
Brugia malayi cytoplasmic intermediate filament protein 0.0043 0.0101 0.0225
Echinococcus multilocularis caspase 2 0.0265 0.1037 0.1037
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.001 0.0077
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.001 0.0077
Brugia malayi ecdysteroid receptor 0.0084 0.0273 0.061
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.001 0.0038
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0111 0.0386 0.1158
Brugia malayi hypothetical protein 0.0122 0.0434 0.0971
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.001 0.0022
Schistosoma mansoni short chain dehydrogenase 0.002 0.0005 0.0006
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0031 0.0052 0.0413
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0021 0.001 0.001
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0031 0.0052 0.0096
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0173 0.0649 0.0743
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0005 0.0011
Schistosoma mansoni alpha-glucosidase 0.0296 0.1168 0.1336
Schistosoma mansoni niemann-pick C1 (NPC1) 0.01 0.0343 0.0393
Plasmodium vivax SET domain protein, putative 0.0155 0.0575 0.4568
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.011 0.0384 0.1708
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0076 0.0241 0.0468
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.001 0.0077
Schistosoma mansoni DNA ligase IV 0.0031 0.0052 0.006
Mycobacterium ulcerans ketoacyl reductase 0.002 0.0005 0.0011
Trypanosoma cruzi short-chain dehydrogenase, putative 0.002 0.0005 0.0043
Trypanosoma brucei hypothetical protein, conserved 0.0111 0.0386 0.307
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.002 0.0005 0.0043
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0096 0.0324 0.0324
Echinococcus granulosus peptidase Clp S14 family 0.005 0.0132 0.0151
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0161 0.1282
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0012
Schistosoma mansoni chromosome transmission fidelity factor 0.0031 0.0052 0.006
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0084 0.0273 0.061
Onchocerca volvulus 0.0047 0.0116 0.0217
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0031 0.0052 0.022
Treponema pallidum NADH oxidase 0.011 0.0384 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0005 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0184 0.1464
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0029 0.0043 0.012
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.002 0.0005 0.0013
Schistosoma mansoni peptidase Clp (S14 family) 0.0077 0.0244 0.0279
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0024 0.0094
Mycobacterium tuberculosis Probable shortchain dehydrogenase 0.002 0.0005 0.0007
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.001 0.0013
Loa Loa (eye worm) hypothetical protein 0.0432 0.1742 0.3896
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0084 0.0273 0.0273
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0084 0.0273 0.0273
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Echinococcus granulosus steroid dehydrogenase 0.002 0.0005 0.0006
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0029 0.0043 0.0178
Treponema pallidum oxidoreductase 0.0029 0.0043 0.0325
Brugia malayi nuclear receptor NHR-67 0.0039 0.0086 0.0193
Echinococcus multilocularis neuropeptide s receptor 0.0939 0.3881 0.3881
Loa Loa (eye worm) hypothetical protein 0.0039 0.0086 0.0193
Plasmodium vivax metacaspase 1, putative 0.0137 0.0498 0.396
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0022
Echinococcus multilocularis thioredoxin glutathione reductase 0.0321 0.1274 0.1274
Schistosoma mansoni hypothetical protein 0.1219 0.5065 0.5797
Chlamydia trachomatis DNA ligase 0.0031 0.0052 0.0273
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0137 0.0498 0.0972
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Echinococcus multilocularis dnaJ subfamily B 0.0459 0.1858 0.1858
Brugia malayi Muscleblind-like protein 0.015 0.0553 0.1238
Mycobacterium tuberculosis Possible fatty acyl-CoA reductase 0.002 0.0005 0.0007
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 16 0.0021 0.001 0.0011
Schistosoma mansoni short chain dehydrogenase 0.002 0.0005 0.0006
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0244 0.6034
Loa Loa (eye worm) hypothetical protein 0.0039 0.0086 0.0192
Loa Loa (eye worm) hypothetical protein 0.015 0.0553 0.1238
Plasmodium falciparum thioredoxin reductase 0.0317 0.1259 1
Trypanosoma brucei NADH dehydrogenase 0.0029 0.0043 0.0339
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0028 0.0039 0.0313
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1078 0.4471 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0052 0.0116
Loa Loa (eye worm) hypothetical protein 0.008 0.0258 0.0576
Mycobacterium ulcerans short-chain dehydrogenase 0.002 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.015 0.0553 0.1238
Toxoplasma gondii PHD-finger domain-containing protein 0.0019 0.0001 0.0008
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0265 0.1037 0.2321
Echinococcus multilocularis glutamate synthase 0.0029 0.0043 0.0043
Trypanosoma brucei 3-ketoacyl-CoA reductase, putative 0.002 0.0005 0.0043
Onchocerca volvulus 0.0084 0.0273 0.0525
Brugia malayi oxidoreductase 0.002 0.0005 0.0012
Schistosoma mansoni nuclear receptor nhr-48 0.0039 0.0086 0.0099
Loa Loa (eye worm) hypothetical protein 0.0196 0.0748 0.1673
Echinococcus granulosus caspase 0.0363 0.145 0.1659
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0003 0.0007
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0029 0.0043 0.0339
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.002 0.0005 0.0013
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0005 0.0043
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.0447 0.0512
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0084 0.0273 0.061
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0005 0.0043
Giardia lamblia Kinase, CMGC MAPK 0.005 0.0129 0.1693
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0012
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0077 0.0244 0.0547
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.001 0.0013
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.014 0.0512 0.407
Echinococcus multilocularis retinol dehydrogenase 11 0.002 0.0005 0.0005
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0077 0.0244 0.1083
Loa Loa (eye worm) oxidoreductase 0.002 0.0005 0.0012
Trypanosoma brucei metacaspase 5, putative 0.0137 0.0498 0.396
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0005 0.0043
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0024 0.019
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0021 0.001 0.009
Trypanosoma cruzi metacaspase, putative 0.0137 0.0498 0.396
Mycobacterium tuberculosis Conserved protein 0.0111 0.0386 0.1158
Brugia malayi hypothetical protein 0.0021 0.001 0.0022
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0042 0.0096 0.076
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0184 0.1464
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.001 0.0077
Toxoplasma gondii hypothetical protein 0.0021 0.001 0.0077
Schistosoma mansoni tar DNA-binding protein 0.0657 0.269 0.3079
Brugia malayi exodeoxyribonuclease III family protein 0.0077 0.0244 0.0547
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.001 0.0038
Trypanosoma cruzi metacaspase, putative 0.0137 0.0498 0.396
Schistosoma mansoni ap endonuclease 0.0077 0.0244 0.028
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0077 0.0244 0.1362
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0707 0.2902 0.8755
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.001 0.0013
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.019 0.0723 0.2174
Loa Loa (eye worm) hypothetical protein 0.0044 0.0106 0.0237
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0022
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0084 0.0273 0.0312
Echinococcus granulosus thioredoxin glutathione reductase 0.0321 0.1274 0.1458
Schistosoma mansoni lamin 0.008 0.0258 0.0295
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.001 0.0077
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.001 0.0077
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0024 0.0054
Entamoeba histolytica thioredoxin reductase, putative 0.0029 0.0043 0.0224
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0029 0.0043 0.0987
Toxoplasma gondii LsmAD domain-containing protein 0.0103 0.0352 0.2799
Trichomonas vaginalis hydroxyacyl dehydrogenase, putative 0.002 0.0005 0.0005
Echinococcus granulosus ubiquitin specific protease 41 0.0196 0.0748 0.0856
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0203 0.0775 0.1511
Loa Loa (eye worm) hypothetical protein 0.0047 0.0116 0.0259
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.011 0.0384 0.1149
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0046 0.0114 0.013
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Entamoeba histolytica hypothetical protein 0.0114 0.0399 0.2235
Echinococcus multilocularis peregrin 0.0062 0.0179 0.0179
Schistosoma mansoni microtubule-associated protein tau 0.2089 0.8737 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0137 0.0498 0.0972
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0084 0.0273 0.0312
Echinococcus granulosus retinol dehydrogenase 11 0.002 0.0005 0.0006
Echinococcus multilocularis histone acetyltransferase MYST2 0.0053 0.0143 0.0143
Mycobacterium tuberculosis Probable lipase LipE 0.0111 0.0386 0.1158
Leishmania major ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.001 0.0077
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.011 0.0384 0.3048
Plasmodium falciparum replication factor C subunit 1, putative 0.0031 0.0052 0.0413
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0025 0.0029
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.011 0.0384 0.3048
Loa Loa (eye worm) hypothetical protein 0.0039 0.0086 0.0193
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.019 0.0723 0.3231
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.011 0.0384 0.3048
Loa Loa (eye worm) hypothetical protein 0.0039 0.0086 0.0193
Trypanosoma cruzi NAD(P)-dependent oxidoreductase, putative 0.002 0.0005 0.0043
Trypanosoma brucei beta-ketoacyl-ACP reductase 3, putative 0.002 0.0005 0.0043
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0137 0.0498 0.0972
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0003 0.0024
Schistosoma mansoni hypothetical protein 0.0459 0.1858 0.2126
Mycobacterium tuberculosis Probable short-chain type oxidoreductase 0.002 0.0005 0.0007
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.001 0.0013
Brugia malayi dehydrogenases, short chain protein 2 0.002 0.0005 0.0012
Mycobacterium tuberculosis Probable lipase LipD 0.0111 0.0386 0.1158
Schistosoma mansoni short chain dehydrogenase 0.002 0.0005 0.0006
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.0386 0.0752
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.001 0.0077
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0116 0.0133
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0047 0.0116 0.0133
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0005 0.0012
Leishmania major short chain dehydrogenase/reductase, putative 0.002 0.0005 0.0043
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.001 0.0038
Loa Loa (eye worm) hypothetical protein 0.0023 0.0017 0.0038
Leishmania major 3-keto-dihydrosphingosine reductase 0.002 0.0005 0.0043
Schistosoma mansoni short chain dehydrogenase 0.002 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0111 0.0386 0.0864
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0084 0.0273 0.061
Mycobacterium tuberculosis Probable short-chain dehydrogenase/reductase 0.002 0.0005 0.0007
Schistosoma mansoni steroid dehydrogenase 0.002 0.0005 0.0006
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.001 0.0022
Echinococcus multilocularis neuropeptide receptor A26 0.0939 0.3881 0.3881
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0077 0.0244 0.1942
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0116 0.0133
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0047 0.0116 0.0217
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.019 0.0723 0.0827
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0024 0.0094
Echinococcus granulosus 5'partial|Ubiquitin carboxyl terminal hydrolase 48 0.0021 0.001 0.0011
Toxoplasma gondii hypothetical protein 0.0026 0.0031 0.0248
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.001 0.0022
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0196 0.0748 0.0856
Trypanosoma brucei 3-keto-dihydrosphingosine reductase 0.002 0.0005 0.0043
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0021 0.001 0.0011
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0077 0.0244 0.1942
Plasmodium vivax ataxin-2 like protein, putative 0.0103 0.0352 0.2799
Brugia malayi Nuclear hormone receptor E75 0.0039 0.0086 0.0193
Mycobacterium ulcerans short-chain membrane-associated dehydrogenase 0.002 0.0005 0.0011
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0039 0.0086 0.0193
Echinococcus multilocularis steroid dehydrogenase 0.002 0.0005 0.0005
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0129 0.0148
Schistosoma mansoni thyroid hormone receptor 0.0084 0.0273 0.0312
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0029 0.0043 0.0339
Mycobacterium ulcerans dehydrogenase/reductase 0.002 0.0005 0.0011
Schistosoma mansoni hypothetical protein 0.0128 0.0459 0.0525
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.002 0.0005 0.0043
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0184 0.1464
Trypanosoma cruzi metacaspase 5, putative 0.0137 0.0498 0.396
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0184 0.1464
Toxoplasma gondii selenide, water dikinase 0.0029 0.0043 0.0339
Schistosoma mansoni oxidoreductase short chain dehydrogenase/reductase family 0.002 0.0005 0.0006
Echinococcus granulosus SAM and MBT domain containing protein 0.0047 0.0116 0.0133
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0022
Loa Loa (eye worm) PHD-finger family protein 0.0059 0.0169 0.0378
Entamoeba histolytica disulphide oxidoreductase, putative 0.0029 0.0043 0.0224
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0084 0.0273 0.061
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0005 0.0012
Plasmodium vivax replication factor C subunit 1, putative 0.0031 0.0052 0.0413
Onchocerca volvulus 0.0128 0.0459 0.089
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0003 0.0024
Brugia malayi hypothetical protein 0.0114 0.0399 0.0893
Toxoplasma gondii hypothetical protein 0.0048 0.0122 0.0966
Trypanosoma cruzi trypanothione reductase, putative 0.011 0.0384 0.3048
Leishmania major mitochondrial DNA polymerase beta 0.0297 0.1172 0.9312
Mycobacterium leprae Probable lipase LipE 0.0111 0.0386 0.1151
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0029 0.0043 0.0096
Plasmodium vivax thioredoxin reductase, putative 0.0317 0.1259 1
Echinococcus granulosus cpg binding protein 0.0036 0.0072 0.0082
Mycobacterium ulcerans carveol-like dehydrogenase 0.002 0.0005 0.0011
Schistosoma mansoni ubiquitin-specific peptidase 22 (C19 family) 0.0021 0.001 0.0011
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0029 0.0043 0.0178
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 0.0021 0.001 0.001
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0111 0.0386 0.0442
Trichomonas vaginalis glutaminase, putative 0.0548 0.2231 0.4373
Loa Loa (eye worm) hypothetical protein 0.0031 0.0052 0.0116
Brugia malayi Glycosyl hydrolases family 31 protein 0.0344 0.137 0.3064
Echinococcus multilocularis neutral alpha glucosidase AB 0.0076 0.0241 0.0241
Trypanosoma brucei protein kinase, putative 0.005 0.0129 0.1026
Mycobacterium leprae conserved hypothetical protein 0.0111 0.0386 0.1151
Mycobacterium ulcerans short-chain dehydrogenase 0.002 0.0005 0.0011
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.001 0.0077
Trichomonas vaginalis glutathione reductase, putative 0.011 0.0384 0.0747
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0084 0.0273 0.061
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 14 0.0021 0.001 0.001
Echinococcus multilocularis protein dispatched 1 0.0048 0.0124 0.0124
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 24 0.0021 0.001 0.0011
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.001 0.0077
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0021 0.001 0.0077
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.001 0.0022
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.011 0.0384 0.0439
Mycobacterium ulcerans lipase LipD 0.0111 0.0386 0.1721
Onchocerca volvulus 0.0021 0.001 0.0009
Giardia lamblia NADH oxidase lateral transfer candidate 0.011 0.0384 0.5108
Schistosoma mansoni alpha glucosidase 0.0076 0.0241 0.0276
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.001 0.0022
Loa Loa (eye worm) oxidoreductase 0.002 0.0005 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0084 0.0273 0.061
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0005 0.0011
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0099 0.0221
Trypanosoma brucei trypanothione reductase 0.0317 0.1259 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Loa Loa (eye worm) oxidoreductase 0.002 0.0005 0.0012
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0155 0.0575 0.4568
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0021 0.001 0.0011
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0025 0.0025
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0029 0.0043 0.0224
Schistosoma mansoni survival motor neuron protein 0.0048 0.012 0.0138
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0003 0.0024
Loa Loa (eye worm) hypothetical protein 0.0099 0.0337 0.0753
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.011 0.0384 0.3048
Onchocerca volvulus 0.0039 0.0086 0.0159
Mycobacterium tuberculosis Conserved protein 0.0111 0.0386 0.1158
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0044 0.0106 0.0122
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0084 0.0273 0.0312
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Brugia malayi glutamate synthase 0.0029 0.0043 0.0096
Echinococcus multilocularis polycomb protein SCMH1 0.0047 0.0116 0.0116
Entamoeba histolytica short chain dehydrogenase family protein 0.002 0.0005 0.0013
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0005 0.0043
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.002 0.0005 0.0043
Loa Loa (eye worm) oxidoreductase 0.002 0.0005 0.0012
Mycobacterium ulcerans oxidoreductase 0.002 0.0005 0.0011
Schistosoma mansoni glutamate synthase 0.0029 0.0043 0.0049
Schistosoma mansoni transcription factor LCR-F1 0.0114 0.0399 0.0457
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0029 0.0043 0.012
Echinococcus multilocularis epidermal retinal dehydrogenase 2 0.002 0.0005 0.0005
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.001 0.0022
Schistosoma mansoni ubiquitin-specific peptidase 45 (C19 family) 0.0021 0.001 0.0011
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0039 0.0086 0.0099
Trypanosoma cruzi short chain dehydrogenase/reductase, putative 0.002 0.0005 0.0043
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0111 0.0386 0.0442
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0005 0.0011
Toxoplasma gondii PHD-finger domain-containing protein 0.0059 0.0169 0.1341
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.001 0.0077
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0028 0.0039 0.0071
Loa Loa (eye worm) hypothetical protein 0.0039 0.0086 0.0193
Echinococcus granulosus lamin dm0 0.008 0.0258 0.0295
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Loa Loa (eye worm) hypothetical protein 0.0173 0.0649 0.1451
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0005 0.0011
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0805 0.3315 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0137 0.0498 0.0972
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Schistosoma mansoni steroid dehydrogenase 0.002 0.0005 0.0006
Echinococcus multilocularis jumonji domain containing protein 0.0082 0.0266 0.0266
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0003 0.0024
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0029 0.0043 0.0339
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0029 0.0043 0.0339
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0076 0.0241 0.1344
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0042 0.0096 0.076
Echinococcus granulosus caspase 3 0.0225 0.0871 0.0997
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0029 0.0043 0.0078
Brugia malayi ubiquitin carboxyl-terminal hydrolase 46 0.0021 0.001 0.0022
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0084 0.0273 0.0273
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.001 0.0077
Onchocerca volvulus 0.0155 0.0575 0.1118
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0005 0.0043
Echinococcus granulosus ecdysone induced protein 78C 0.0084 0.0273 0.0312
Brugia malayi glutaminase DH11.1 0.0548 0.2231 0.4991
Loa Loa (eye worm) hypothetical protein 0.0046 0.0112 0.0251
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.001 0.0013
Echinococcus multilocularis ubiquitin specific peptidase 42 (C19 family) 0.0021 0.001 0.001
Loa Loa (eye worm) DR-78 0.0039 0.0086 0.0193
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.014 0.0512 0.407
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.001 0.0077
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.011 0.0384 0.3048
Onchocerca volvulus 0.0028 0.0036 0.006
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0003 0.0024
Trypanosoma cruzi PAB1-binding protein , putative 0.0103 0.0352 0.2799
Schistosoma mansoni jumonji/arid domain-containing protein 0.0075 0.0237 0.0272
Echinococcus multilocularis tumor protein p63 0.0338 0.1347 0.1347
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.001 0.0022
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0053 0.0143 0.0164
Echinococcus multilocularis caspase 8 0.0137 0.0498 0.0498
Trypanosoma cruzi NADH dehydrogenase, putative 0.0029 0.0043 0.0339
Schistosoma mansoni patched 1 0.0042 0.0099 0.0113
Loa Loa (eye worm) oxidoreductase 0.002 0.0005 0.0012
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0184 0.1464
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0024 0.0063
Loa Loa (eye worm) hypothetical protein 0.0037 0.0077 0.0171
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.001 0.0022
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Schistosoma mansoni ap endonuclease 0.0077 0.0244 0.028
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase family 2 protein 0.0021 0.001 0.0077
Schistosoma mansoni topbp1 0.0031 0.0052 0.006
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0447 0.1993
Loa Loa (eye worm) RNA binding protein 0.0657 0.269 0.6017
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.001 0.0038
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0241 0.1917
Brugia malayi ubiquitin specific protease 14 0.0021 0.001 0.0022
Brugia malayi hypothetical protein 0.002 0.0005 0.0012
Plasmodium vivax hypothetical protein, conserved 0.0059 0.0169 0.1341
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0196 0.0748 0.0856
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0029 0.0043 0.0049
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0024 0.0094
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.011 0.0384 0.0384
Brugia malayi Pax transcription activation domain interacting protein 0.0031 0.0052 0.0116
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0005 0.0043
Echinococcus granulosus microtubule associated protein 2 0.2089 0.8737 1
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.001 0.0038
Schistosoma mansoni bromodomain containing protein 0.0067 0.0201 0.0231
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0129 0.0248
Schistosoma mansoni carbonyl reductase 0.002 0.0005 0.0006
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0084 0.0273 0.0273
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0005 0.0012
Loa Loa (eye worm) hypothetical protein 0.0039 0.0086 0.0193
Brugia malayi PHD-finger family protein 0.0027 0.0035 0.0079
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0084 0.0273 0.061
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.001 0.0077
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Trypanosoma cruzi trypanothione reductase, putative 0.0317 0.1259 1
Leishmania major hypothetical protein, conserved 0.0029 0.0043 0.0339
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.001 0.0013
Echinococcus granulosus histone acetyltransferase MYST2 0.0053 0.0143 0.0164
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0005 0.0007
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0125 0.0447 0.0447
Schistosoma mansoni ubiquitin-specific peptidase 24 (C19 family) 0.0021 0.001 0.0011
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0084 0.0273 0.0312
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.011 0.0384 0.3048
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0056 0.0124
Echinococcus granulosus peregrin 0.0062 0.0179 0.0205
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.0021 0.001 0.001
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0096 0.0324 0.0726
Loa Loa (eye worm) hypothetical protein 0.0039 0.0086 0.0193
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.001 0.0022
Plasmodium falciparum ubiquitin specific protease, putative 0.0021 0.001 0.0077
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0012
Echinococcus granulosus lysine specific demethylase 5A 0.0075 0.0237 0.0272
Echinococcus granulosus tumor protein p63 0.0338 0.1347 0.1542
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0024 0.0094
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0005 0.0012
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.011 0.0384 0.3048
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0084 0.0273 0.061
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0196 0.0748 0.0856
Brugia malayi nuclear hormone receptor 0.0039 0.0086 0.0193
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0023 0.0016 0.0018
Echinococcus multilocularis lysine specific demethylase 5A 0.0072 0.0221 0.0221
Trichomonas vaginalis conserved hypothetical protein 0.0137 0.0498 0.0972
Loa Loa (eye worm) hypothetical protein 0.0031 0.0052 0.0116
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Loa Loa (eye worm) hypothetical protein 0.0084 0.0273 0.061
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0005 0.0011
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.0001 0.0008
Brugia malayi hypothetical protein 0.0031 0.0052 0.0116
Echinococcus multilocularis dna polymerase kappa 0.002 0.0003 0.0003
Brugia malayi Pre-SET motif family protein 0.1078 0.4471 1
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0063 0.0186 0.0213
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0005 0.0043
Onchocerca volvulus Alhambra homolog 0.0059 0.0169 0.0321
Leishmania major hypothetical protein, conserved 0.0029 0.0043 0.0339
Plasmodium vivax hypothetical protein, conserved 0.002 0.0005 0.0043
Mycobacterium ulcerans glutamate synthase subunit beta 0.0029 0.0043 0.0178
Schistosoma mansoni steroid dehydrogenase 0.002 0.0005 0.0006
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0031 0.0052 0.0413
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0031 0.0052 0.0096
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0099 0.0113
Echinococcus multilocularis Dehydrogenase:reductase SDR family 0.002 0.0005 0.0005
Onchocerca volvulus 0.0111 0.0386 0.0748
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.001 0.0077
Plasmodium vivax hypothetical protein, conserved 0.0137 0.0498 0.396
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0111 0.0386 0.1721
Brugia malayi nuclear receptor RXR 0.0044 0.0106 0.0237
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 47 0.0021 0.001 0.001
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0137 0.0498 0.0972
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0029 0.0043 0.0078
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0005 0.0043
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0084 0.0273 0.0273
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0111 0.0386 0.0864
Schistosoma mansoni steroid dehydrogenase 0.002 0.0005 0.0006
Schistosoma mansoni hypothetical protein 0.0298 0.1178 0.1348
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0039 0.0086 0.0159
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.005 0.0132 0.039
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0005 0.0012
Toxoplasma gondii 3-ketoacyl-CoA reductase, putative 0.002 0.0005 0.0043
Loa Loa (eye worm) hypothetical protein 0.0128 0.0459 0.1026
Schistosoma mansoni lozenge 0.0054 0.0148 0.017
Echinococcus multilocularis survival motor neuron protein 1 0.0233 0.0904 0.0904
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0129 0.1026
Schistosoma mansoni carbonyl reductase 0.002 0.0005 0.0006
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0029 0.0043 0.0043
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0029 0.0043 0.0078
Toxoplasma gondii aldehyde dehydrogenase 0.0125 0.0447 0.3553
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Trypanosoma brucei Metacaspase-4 0.0137 0.0498 0.396
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0196 0.0748 0.1462
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 7 0.0021 0.001 0.0011
Trichomonas vaginalis maltase-glucoamylase, putative 0.0076 0.0241 0.0468
Leishmania major trypanothione reductase 0.0317 0.1259 1
Mycobacterium tuberculosis Probable hydrolase 0.0111 0.0386 0.1158
Brugia malayi Intermediate filament tail domain containing protein 0.008 0.0258 0.0576
Plasmodium falciparum oxidoreductase, short-chain dehydrogenase family, putative 0.002 0.0005 0.0043
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0005 0.0011
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.001 0.0022
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0005 0.0011
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0005 0.0043
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.011 0.0384 1
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0029 0.0043 0.0049
Echinococcus granulosus ubiquitin specific peptidase c family 0.0021 0.001 0.0011
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0029 0.0043 0.0339
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.019 0.0723 0.3231
Trichomonas vaginalis conserved hypothetical protein 0.0137 0.0498 0.0972
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0029 0.0043 0.0043
Trypanosoma cruzi hypothetical protein, conserved 0.002 0.0005 0.0043
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0005 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Brugia malayi RNA binding protein 0.0657 0.269 0.6017
Schistosoma mansoni hypothetical protein 0.0048 0.012 0.0138
Trypanosoma cruzi short chain dehydrogenase, putative 0.002 0.0005 0.0043
Schistosoma mansoni ubiquitin-specific peptidase 10 (C19 family) 0.0021 0.001 0.0011
Mycobacterium ulcerans hypothetical protein 0.0156 0.0579 0.2586
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.001 0.0077
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0052 0.0096
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0029 0.0043 0.0178
Trichomonas vaginalis glutamate synthase, putative 0.0029 0.0043 0.0078
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Onchocerca volvulus 0.0199 0.0758 0.1478
Schistosoma mansoni alpha-glucosidase 0.0296 0.1168 0.1336
Toxoplasma gondii oxidoreductase, putative 0.002 0.0005 0.0043
Trypanosoma cruzi FHA domain containing protein, putative 0.0031 0.0052 0.0413
Loa Loa (eye worm) oxidoreductase 0.002 0.0005 0.0012
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.011 0.0384 0.0439
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.001 0.0038
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.001 0.0077
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Echinococcus multilocularis beta LACTamase domain containing family member 0.0111 0.0386 0.0386
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.001 0.0077
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Leishmania major acetoin dehydrogenase e3 component-like protein 0.011 0.0384 0.3048
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0196 0.0748 0.0856
Echinococcus granulosus tar DNA binding protein 0.0657 0.269 0.3079
Brugia malayi glutathione reductase 0.0317 0.1259 0.2815
Trypanosoma brucei PAB1-binding protein , putative 0.0103 0.0352 0.2799
Brugia malayi Niemann-Pick C1 protein precursor 0.0099 0.0337 0.0753
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0039 0.0071
Schistosoma mansoni nuclear hormone receptor 0.0039 0.0086 0.0099
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0024 0.0118
Leishmania major short chain dehydrogenase-like protein 0.002 0.0005 0.0043
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0039 0.0086 0.0193
Schistosoma mansoni ubiquitin-specific peptidase 16 (C19 family) 0.0021 0.001 0.0011
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.0021 0.001 0.0077
Echinococcus multilocularis retinol dehydrogenase 11 0.002 0.0005 0.0005
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0137 0.0498 0.396
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0149 0.0548 0.0627
Leishmania major metacaspase, putative 0.0137 0.0498 0.396
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0052 0.0413
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0005 0.0012
Schistosoma mansoni carbonyl reductase 0.002 0.0005 0.0006
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0005 0.0043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.001 0.0077
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.0021 0.001 0.001
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0137 0.0498 0.1115
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.001 0.0077
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Entamoeba histolytica oxidoreductase, short chain dehydrogenase/reductase family 0.002 0.0005 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0003 0.0024
Trichomonas vaginalis alpha-glucosidase, putative 0.0076 0.0241 0.0468
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0184 0.1464
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0003 0.0007
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0003 0.0024
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.011 0.0384 0.3048
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0005 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0003 0.0024
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0033 0.0059 0.0067
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 14 0.0021 0.001 0.0077
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0005 0.0011
Trypanosoma cruzi short-chain dehydrogenase, putative 0.002 0.0005 0.0043
Schistosoma mansoni hypothetical protein 0.0041 0.0092 0.0105
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0005 0.0007
Trypanosoma cruzi hypothetical protein, conserved 0.0111 0.0386 0.307
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0022
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Mycobacterium ulcerans hypothetical protein 0.0025 0.0024 0.0094
Echinococcus granulosus intermediate filament protein 0.008 0.0258 0.0295
Plasmodium vivax ubiquitin specific protease, putative 0.0021 0.001 0.0077
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.0021 0.001 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0052 0.0096
Trichomonas vaginalis estradiol 17 beta-dehydrogenase, putative 0.002 0.0005 0.0005
Plasmodium falciparum metacaspase 1 0.0137 0.0498 0.396
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0029 0.0043 0.0224
Echinococcus multilocularis nuclear receptor nhr 48 0.0039 0.0086 0.0086
Echinococcus multilocularis apoptotic protease activating factor 1 0.0128 0.0459 0.0459
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.001 0.0013
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.001 0.0022
Leishmania major cathepsin L-like protease 0.0063 0.0184 0.1464
Leishmania major DNA polymerase kappa, putative 0.002 0.0003 0.0024
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.001 0.0077
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0077 0.0244 0.0244
Loa Loa (eye worm) intermediate filament protein 0.008 0.0258 0.0576
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0128 0.0147
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0244 0.1937
Loa Loa (eye worm) hypothetical protein 0.0084 0.0273 0.061
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 1, putative 0.0021 0.001 0.0077
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0137 0.0498 0.0972
Giardia lamblia PHD finger protein 15 0.0059 0.0169 0.2226
Leishmania major hypothetical protein, conserved 0.0111 0.0386 0.307
Trypanosoma cruzi hypothetical protein, conserved 0.0031 0.0052 0.0413
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0084 0.0273 0.061
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.0021 0.001 0.0077
Brugia malayi orphan nuclear receptor NR2E1 0.0039 0.0086 0.0193
Brugia malayi mbt repeat family protein 0.0047 0.0116 0.0259
Entamoeba histolytica hypothetical protein 0.002 0.0005 0.0013
Loa Loa (eye worm) hypothetical protein 0.0203 0.0775 0.1733
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0077 0.0244 0.1942
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.001 0.0038
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0193 0.0736 0.0842
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0005 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0043 0.0339
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0039 0.0071
Schistosoma mansoni hypothetical protein 0.0059 0.0169 0.0193
Brugia malayi hypothetical protein 0.0432 0.1742 0.3896
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0076 0.0241 0.0468
Schistosoma mansoni sulfide quinone reductase 0.0029 0.0043 0.0049
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.001 0.0013
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0024 0.0056
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0039 0.0071
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0029 0.0043 0.0178
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0084 0.0273 0.0312
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0005 0.0012
Mycobacterium ulcerans short-chain type oxidoreductase 0.002 0.0005 0.0011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0184 0.1464
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0005 0.0005
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 12 0.0021 0.001 0.0011
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0005 0.0005
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0029 0.0043 0.0078
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0084 0.0273 0.061
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0029 0.0043 0.0339
Entamoeba histolytica hypothetical protein 0.0114 0.0399 0.2235
Loa Loa (eye worm) hypothetical protein 0.005 0.0132 0.0295
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0065 0.0145
Trypanosoma cruzi metacaspase 5, putative 0.0137 0.0498 0.396
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.001 0.0077
Trypanosoma brucei beta-ketoacyl-ACP reductase 2 0.002 0.0005 0.0043
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Schistosoma mansoni steroid dehydrogenase 0.002 0.0005 0.0006
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0129 0.1026
Leishmania major hypothetical protein, conserved 0.002 0.0005 0.0043
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.001 0.0077
Loa Loa (eye worm) hypothetical protein 0.0101 0.0347 0.0776
Loa Loa (eye worm) jmjC domain-containing protein 0.0075 0.0237 0.0531
Echinococcus granulosus Niemann Pick C1 protein 0.0141 0.0516 0.059
Loa Loa (eye worm) hypothetical protein 0.0111 0.0386 0.0864
Echinococcus granulosus carbonyl reductase 1 0.002 0.0005 0.0006
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0024 0.0054
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0005 0.0043
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0022
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0029 0.0043 0.0078
Onchocerca volvulus 0.0021 0.001 0.0009
Schistosoma mansoni zinc finger protein 0.0039 0.0086 0.0099
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0005 0.0007
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0084 0.0273 0.0312
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0244 0.1081
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0039 0.0083 0.0095
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0021 0.001 0.001
Schistosoma mansoni ubiquitin-specific peptidase 4 (C19 family) 0.0021 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0022
Leishmania major dehydrogenase-like protein 0.002 0.0005 0.0043
Trichomonas vaginalis set domain proteins, putative 0.1227 0.5099 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0184 0.1464
Brugia malayi steroid hormone receptor 0.0084 0.0273 0.061
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.001 0.0077
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.001 0.0038
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0005 0.0012
Schistosoma mansoni peptidase 0.0022 0.0012 0.0013
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Loa Loa (eye worm) hypothetical protein 0.0042 0.0096 0.0215
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0023 0.0016 0.0016
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.001 0.0077
Trichomonas vaginalis glutamate synthase, putative 0.0029 0.0043 0.0078
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0074 0.0232 0.0266
Loa Loa (eye worm) oxidoreductase 0.002 0.0005 0.0012
Onchocerca volvulus 0.0039 0.0086 0.0159
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0012
Echinococcus granulosus dnaJ subfamily B 0.0459 0.1858 0.2126
Loa Loa (eye worm) hypothetical protein 0.0042 0.0099 0.0221
Schistosoma mansoni nuclear hormone receptor 0.0084 0.0273 0.0312
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0099 0.0113
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0005 0.0007
Trypanosoma brucei short-chain dehydrogenase, putative 0.002 0.0005 0.0043
Leishmania major hypothetical protein, conserved 0.002 0.0005 0.0043
Onchocerca volvulus 0.008 0.0258 0.0495
Trypanosoma brucei metacaspase MCA2 0.0137 0.0498 0.396
Trichomonas vaginalis short-chain dehydrogenases/reductase, putative 0.002 0.0005 0.0005
Echinococcus granulosus histone lysine methyltransferase setb 0.0173 0.0649 0.0743
Brugia malayi Glycosyl hydrolases family 31 protein 0.0076 0.0241 0.054
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0029 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0084 0.0273 0.061
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.0021 0.001 0.0011
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.0021 0.001 0.0011
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0076 0.0241 0.1917
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0099 0.0188
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0084 0.0273 0.0273
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0029 0.0043 0.0096
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0111 0.0386 0.1158
Schistosoma mansoni hypothetical protein 0.0019 0.0001 0.0001
Echinococcus multilocularis tar DNA binding protein 0.0657 0.269 0.269
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.019 0.0723 0.0723
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0005 0.0011
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Brugia malayi Pre-SET motif family protein 0.0155 0.0575 0.1286
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0044 0.0106 0.0237
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0029 0.0043 0.0096
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0184 0.1464
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0125 0.0447 0.1341
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Brugia malayi nuclear receptor NHR-88 0.0039 0.0086 0.0193
Schistosoma mansoni hypothetical protein 0.0029 0.0043 0.0049
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0005 0.0005
Schistosoma mansoni short chain dehydrogenase 0.002 0.0005 0.0006
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0137 0.0498 0.0972
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0724 0.2974 0.897
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0084 0.0273 0.0525
Toxoplasma gondii sterol carrier protein-2 HAD-2SCP-2 0.002 0.0005 0.0043
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0324 0.0371
Brugia malayi Bromodomain containing protein 0.0062 0.0179 0.0401
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0005 0.0043
Giardia lamblia Replication factor C, subunit 1 0.0031 0.0052 0.0658
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0005 0.0043
Trypanosoma brucei hypothetical protein, conserved 0.0029 0.0043 0.0339
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 46 0.0021 0.001 0.0022
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0029 0.0043 0.012
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0021 0.001 0.0013
Plasmodium falciparum ataxin-2 like protein, putative 0.0103 0.0352 0.2799
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0005 0.0012
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0005 0.0007
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.001 0.0077
Echinococcus granulosus beta LACTamase domain containing family member 0.0111 0.0386 0.0442
Loa Loa (eye worm) hypothetical protein 0.0039 0.0086 0.0193
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Brugia malayi MAP kinase sur-1 0.005 0.0129 0.0289
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0244 0.1081
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 12 0.0021 0.001 0.001
Plasmodium vivax hypothetical protein, conserved 0.0021 0.001 0.0077
Loa Loa (eye worm) hypothetical protein 0.0031 0.0052 0.0116
Leishmania major DNA polymerase eta, putative 0.002 0.0003 0.0024
Onchocerca volvulus 0.1227 0.5099 1
Onchocerca volvulus 0.0048 0.012 0.0226
Schistosoma mansoni glutaminase 0.0548 0.2231 0.2554
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.001 0.0022
Leishmania major dihydrolipoamide dehydrogenase, putative 0.011 0.0384 0.3048
Brugia malayi PHD-finger family protein 0.0059 0.0169 0.0378
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0084 0.0273 0.0312
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0029 0.0043 0.0113
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.002 0.0005 0.0007
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0125 0.0447 0.3553
Echinococcus multilocularis transient receptor potential cation channel 0.002 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.001 0.0013
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 5 0.0021 0.001 0.0011
Loa Loa (eye worm) hypothetical protein 0.0432 0.1742 0.3896
Echinococcus granulosus expressed conserved protein 0.0093 0.0311 0.0356
Brugia malayi hypothetical protein 0.0044 0.0106 0.0237
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0053 0.0143 0.032
Brugia malayi nuclear receptor RXR 0.0039 0.0086 0.0193
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0005 0.0011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0184 0.1464
Loa Loa (eye worm) hypothetical protein 0.0111 0.0386 0.0864
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.001 0.0077
Loa Loa (eye worm) hypothetical protein 0.005 0.0128 0.0287
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0005 0.0043
Mycobacterium ulcerans dehydrogenase/decarboxylase protein 0.002 0.0005 0.0011
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0029 0.0043 0.0049
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0005 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.001 0.0013
Onchocerca volvulus Huntingtin homolog 0.0122 0.0434 0.0842
Plasmodium vivax ferrodoxin reductase, putative 0.0029 0.0043 0.0339
Onchocerca volvulus 0.0111 0.0386 0.0748
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0046 0.0114 0.0114
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0081 0.026 0.0582
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0193 0.0736 0.0736
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.001 0.0077
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 14 0.0021 0.001 0.0011
Schistosoma mansoni retinal dehydrogenase 0.002 0.0005 0.0006
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0028 0.0039 0.0313
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.001 0.0077
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0029 0.0043 0.0987
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.0021 0.001 0.0011
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0129 0.1026
Echinococcus granulosus nibrin 0.0031 0.0052 0.006
Brugia malayi AF-10 protein 0.0019 0.0001 0.0002
Entamoeba histolytica 3-ketodihydrosphingosine reductase protein, putative 0.002 0.0005 0.0013
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0021 0.0009 0.0074
Trichomonas vaginalis penicillin-binding protein, putative 0.0111 0.0386 0.0752
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Trypanosoma cruzi Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.001 0.0077
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0039 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0022
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Loa Loa (eye worm) hypothetical protein 0.0122 0.0434 0.0971
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0031 0.0052 0.0413
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0031 0.0052 0.0116
Onchocerca volvulus 0.0021 0.001 0.0009
Loa Loa (eye worm) jmjC domain-containing protein 0.0122 0.0434 0.0971
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.001 0.0022
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0129 0.0248
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0084 0.0273 0.061
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.001 0.0022
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.001 0.0038
Onchocerca volvulus 0.0432 0.1742 0.3409
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Schistosoma mansoni aldehyde dehydrogenase 0.0125 0.0447 0.0512
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0029 0.0043 0.0987
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0029 0.0043 0.0078
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0053 0.0143 0.0143
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0029 0.0043 0.012
Brugia malayi Probable ClpP-like protease 0.0077 0.0244 0.0545
Brugia malayi photoreceptor-specific nuclear receptor 0.0084 0.0273 0.061
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0024 0.019
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0019 0.0001 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.001 0.0013
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.0021 0.001 0.0011
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0114 0.0399 0.0457
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0005 0.0007
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0029 0.0043 0.0339
Brugia malayi CXXC zinc finger family protein 0.0032 0.0056 0.0124
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.011 0.0384 0.3048
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0026 0.0031 0.0248
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0084 0.0273 0.061
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0137 0.0498 0.396
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0137 0.0498 0.0972
Loa Loa (eye worm) hypothetical protein 0.0077 0.0244 0.0545
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0024 0.019
Trypanosoma cruzi hypothetical protein, conserved 0.0029 0.0043 0.0339
Schistosoma mansoni ubiquitin-specific peptidase 46 (C19 family) 0.0021 0.001 0.0011
Trypanosoma cruzi short chain dehydrogenase, putative 0.002 0.0005 0.0043
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 2, putative 0.0021 0.001 0.0077
Mycobacterium ulcerans flavoprotein disulfide reductase 0.011 0.0384 0.1708
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.001 0.0013
Echinococcus multilocularis 3 ketodihydrosphingosine reductase 0.002 0.0005 0.0005
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0052 0.0096
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0029 0.0043 0.0113
Brugia malayi hypothetical protein 0.0103 0.0352 0.0788
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0003 0.0003
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.0021 0.001 0.0022
Entamoeba histolytica estradiol 17-beta-dehydrogenase, putative 0.002 0.0005 0.0013
Loa Loa (eye worm) hypothetical protein 0.0122 0.0434 0.0971
Brugia malayi nuclear hormone receptor family member odr-7 0.0039 0.0086 0.0193
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0077 0.0244 0.6305
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.0021 0.001 0.0022
Echinococcus granulosus epidermal retinal dehydrogenase 2 0.002 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0012
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.0001 0.0008
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0005 0.0012
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0129 0.1026
Schistosoma mansoni hypothetical protein 0.0034 0.0065 0.0074
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.011 0.0384 0.3048
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0077 0.0244 0.028
Toxoplasma gondii UBA/TS-N domain-containing protein 0.0021 0.001 0.0077
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0129 0.0289
Loa Loa (eye worm) runx1 0.0054 0.0148 0.0331
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 36 0.0021 0.001 0.001
Brugia malayi N-terminal motif family protein 0.0203 0.0775 0.1733
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.001 0.0077
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.019 0.0723 0.5744
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0084 0.0273 0.061
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.001 0.0077
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.001 0.0077
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.001 0.0077
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0029 0.0043 0.0339
Loa Loa (eye worm) hypothetical protein 0.0111 0.0386 0.0864
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0022
Loa Loa (eye worm) glutaminase 0.0548 0.2231 0.4991
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0029 0.0043 0.0339
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.001 0.0077
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0317 0.1259 0.3791
Mycobacterium ulcerans aldehyde dehydrogenase 0.0125 0.0447 0.1993
Loa Loa (eye worm) glutaminase 2 0.0548 0.2231 0.4991
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0029 0.0043 0.012
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0029 0.0043 0.0078
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0003 0.0024
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0021 0.001 0.0013
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0029 0.0043 0.0224
Trypanosoma cruzi metacaspase, putative 0.0137 0.0498 0.396
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.011 0.0384 0.3048
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.001 0.0077
Loa Loa (eye worm) hypothetical protein 0.0084 0.0273 0.061
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0021 0.001 0.0013
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0025 0.0024 0.0056
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0044 0.0106 0.0122
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0022
Giardia lamblia Hypothetical protein 0.002 0.0005 0.0032
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0184 0.1464
Echinococcus granulosus geminin 0.1219 0.5065 0.5797
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0155 0.0575 0.0658
Loa Loa (eye worm) dehydrogenase 0.002 0.0005 0.0012
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0021 0.001 0.009
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 24 0.0021 0.001 0.001
Schistosoma mansoni short chain dehydrogenase 0.002 0.0005 0.0006
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.011 0.0384 1
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0077 0.0244 0.072
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0024 0.0054
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Echinococcus multilocularis thyroid hormone receptor alpha 0.0084 0.0273 0.0273
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.001 0.0077
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.001 0.0077
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0029 0.0043 0.0049
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0029 0.0043 0.0224
Leishmania major hypothetical protein, conserved 0.002 0.0005 0.0043
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0028 0.0039 0.0071
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.019 0.0723 0.0827
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 16 0.0021 0.001 0.001
Echinococcus granulosus survival motor neuron protein 1 0.0233 0.0904 0.1034
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.001 0.0022
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.001 0.0077
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.001 0.0077
Mycobacterium ulcerans oxidoreductase 0.002 0.0005 0.0011
Trichomonas vaginalis alpha-glucosidase, putative 0.0076 0.0241 0.0468
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0024 0.0118
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0029 0.0043 0.0043
Giardia lamblia Oxidoreductase, short chain dehydrogenase/reductase family 0.002 0.0005 0.0032
Echinococcus multilocularis oxidoreductase 0.002 0.0005 0.0005
Trypanosoma brucei Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.001 0.0077
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0031 0.0052 0.1233
Echinococcus granulosus replication factor c subunit 1 0.0031 0.0052 0.006
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.001 0.0038
Brugia malayi hypothetical protein 0.002 0.0005 0.0012
Brugia malayi Dehydrogenases, short chain protein 30 0.002 0.0005 0.0012
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0077 0.0244 0.0244
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0724 0.2974 0.8971
Brugia malayi ecdysone receptor 0.0039 0.0086 0.0193
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.008 0.0258 0.0576
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0005 0.0011
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0005 0.0011
Brugia malayi Nuclear hormone receptor-like 1 0.0044 0.0106 0.0237
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0039 0.0086 0.0086
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0021 0.001 0.0077
Brugia malayi hypothetical protein 0.0031 0.0052 0.0116
Schistosoma mansoni hypothetical protein 0.0046 0.0114 0.013
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.001 0.0077
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0031 0.0052 0.0141
Schistosoma mansoni short chain dehydrogenase 0.002 0.0005 0.0006
Echinococcus granulosus Nuclear hormone receptor HR96 0.0039 0.0086 0.0099
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0039 0.0071
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0029 0.0043 0.0339
Toxoplasma gondii oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0005 0.0043
Brugia malayi Thioredoxin reductase 0.0317 0.1259 0.2815
Trichomonas vaginalis esterase, putative 0.0111 0.0386 0.0752
Toxoplasma gondii thioredoxin reductase 0.0317 0.1259 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.0028 0.0039 0.0088
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0029 0.0043 0.0339
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0063 0.0186 0.0186
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0005 0.0011
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0022
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0003 0.0003
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0029 0.0043 0.0049
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0129 0.0129
Echinococcus granulosus FTZ F1 alpha 0.0084 0.0273 0.0312
Brugia malayi Cell death protein 3 precursor 0.0265 0.1037 0.2321
Trichomonas vaginalis ap endonuclease, putative 0.0077 0.0244 0.0474
Schistosoma mansoni topbp1 0.0031 0.0052 0.006
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0025 0.0029
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.011 0.0384 1
Echinococcus multilocularis microtubule associated protein 2 0.2089 0.8737 0.8737
Trypanosoma cruzi cysteine peptidase, Clan CA, family C19, putative 0.0021 0.001 0.0077
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0184 0.1464
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.001 0.0077
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0084 0.0273 0.0312
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0196 0.0748 0.5943
Loa Loa (eye worm) hypothetical protein 0.0037 0.0077 0.0171
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 0.0021 0.001 0.0011
Trypanosoma brucei metacaspase 0.0137 0.0498 0.396
Loa Loa (eye worm) programmed cell death 8 0.0029 0.0043 0.0096
Loa Loa (eye worm) MH2 domain-containing protein 0.0125 0.0445 0.0996
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Trichomonas vaginalis penicillin-binding protein, putative 0.0111 0.0386 0.0752
Schistosoma mansoni RAR-like nuclear receptor 0.0084 0.0273 0.0312
Brugia malayi beta-lactamase family protein 0.0111 0.0386 0.0864
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.001 0.0038
Brugia malayi nuclear receptor NHR-88 0.0084 0.0273 0.061
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0199 0.0758 0.0758
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0005 0.0007
Echinococcus granulosus carbonyl reductase 1 0.002 0.0005 0.0006
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0003 0.0024
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0129 0.1026
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0005 0.0011
Schistosoma mansoni steroid dehydrogenase 0.002 0.0005 0.0006
Plasmodium vivax steroid dehydrogenase, putative 0.002 0.0005 0.0043
Onchocerca volvulus 0.0031 0.0052 0.0092
Toxoplasma gondii carbonyl reductase 1, putative 0.002 0.0005 0.0043
Echinococcus multilocularis SAM and MBT domain containing protein 0.0047 0.0116 0.0116
Entamoeba histolytica hypothetical protein 0.0114 0.0399 0.2235
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0012
Toxoplasma gondii ATPase, AAA family protein 0.0031 0.0052 0.0413
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Schistosoma mansoni tar DNA-binding protein 0.0657 0.269 0.3079
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Echinococcus granulosus jumonji domain containing protein 0.0082 0.0266 0.0305
Toxoplasma gondii exonuclease III APE 0.0077 0.0244 0.1942
Echinococcus multilocularis nibrin 0.0031 0.0052 0.0052
Trichomonas vaginalis mercuric reductase, putative 0.011 0.0384 0.0747
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0196 0.0748 0.1673
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0137 0.0498 0.396
Schistosoma mansoni cpg binding protein 0.0036 0.0072 0.0082
Mycobacterium tuberculosis Probable esterase LipL 0.0111 0.0386 0.1158
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Brugia malayi D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor 0.002 0.0005 0.0012
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0111 0.0386 0.1158
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Brugia malayi Nuclear hormone receptor-like 1 0.0044 0.0106 0.0237
Mycobacterium tuberculosis Conserved hypothetical protein 0.0156 0.0579 0.174
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0005 0.0012
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.001 0.0038
Echinococcus multilocularis muscleblind protein 0.015 0.0553 0.0553
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0005 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.001 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0052 0.0096
Leishmania major short chain dehydrogenase, putative 0.002 0.0005 0.0043
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 20 0.0021 0.001 0.0011
Onchocerca volvulus Bile acid receptor homolog 0.0084 0.0273 0.0525
Schistosoma mansoni hypothetical protein 0.1219 0.5065 0.5797
Leishmania major pteridine reductase 1 0.002 0.0005 0.0043
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.001 0.0077
Mycobacterium tuberculosis Possible oxidoreductase 0.002 0.0005 0.0007
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0024 0.0094
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0029 0.0043 0.0339
Brugia malayi hypothetical protein 0.0128 0.0459 0.1026
Trypanosoma brucei glycosyl hydrolase-like protein 0.0028 0.0039 0.0313
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0297 0.1172 0.9312
Loa Loa (eye worm) hypothetical protein 0.0084 0.0273 0.061
Schistosoma mansoni intermediate filament proteins 0.008 0.0258 0.0295
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0003 0.0024
Mycobacterium ulcerans ketoacyl reductase 0.002 0.0005 0.0011
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0005 0.0043
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.0021 0.001 0.009
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0077 0.0244 0.3241
Mycobacterium tuberculosis Probable short chain alcohol dehydrogenase/reductase 0.002 0.0005 0.0007
Echinococcus multilocularis ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase 0.0021 0.001 0.001
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0003 0.0024
Onchocerca volvulus Cell death protein 3 homolog 0.0265 0.1037 0.2026
Schistosoma mansoni short-chain dehydrogenase/reductase 0.002 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0003 0.0007
Brugia malayi MH2 domain containing protein 0.0125 0.0445 0.0996
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0028 0.0039 0.0205
Loa Loa (eye worm) MBCTL1 0.0053 0.0143 0.032
Toxoplasma gondii ABC1 family protein 0.0111 0.0386 0.307
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0031 0.0052 0.0096
Mycobacterium ulcerans glutaminase 0.0548 0.2231 1
Loa Loa (eye worm) hypothetical protein 0.0137 0.0498 0.1115
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0054
Mycobacterium tuberculosis Probable dehydrogenase 0.0724 0.2974 0.8971
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.001 0.0022
Echinococcus multilocularis replication factor c subunit 1 0.0031 0.0052 0.0052
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0012
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0042 0.0096 0.076
Loa Loa (eye worm) hypothetical protein 0.0029 0.0043 0.0096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Plasmodium falciparum glutathione reductase 0.0317 0.1259 1
Leishmania major quinonoid dihydropteridine reductase 0.002 0.0005 0.0043
Mycobacterium tuberculosis Possible oxidoreductase 0.002 0.0005 0.0007
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.001 0.0038
Schistosoma mansoni short chain dehydrogenase 0.002 0.0005 0.0006
Plasmodium vivax glutathione reductase, putative 0.0317 0.1259 1
Leishmania major hypothetical protein, conserved 0.0103 0.0352 0.2799
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0012
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0024 0.0094
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0155 0.0575 0.0575
Loa Loa (eye worm) hypothetical protein 0.0084 0.0273 0.061
Trichomonas vaginalis alpha-glucosidase, putative 0.0028 0.0039 0.0071
Schistosoma mansoni ubiquitin-specific peptidase 9X (C19 family) 0.0021 0.001 0.0011
Echinococcus multilocularis conserved hypothetical protein 0.002 0.0005 0.0005
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.001 0.0038
Schistosoma mansoni short chain dehydrogenase 0.002 0.0005 0.0006
Echinococcus granulosus oxidoreductase 0.002 0.0005 0.0006
Trypanosoma cruzi quinonoid dihydropteridine reductase, putative 0.002 0.0005 0.0043
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0005 0.0012
Brugia malayi nuclear hormone receptor family member nhr-6 0.0039 0.0086 0.0193
Echinococcus granulosus caspase 2 0.0265 0.1037 0.1187
Treponema pallidum thioredoxin reductase (trxB) 0.0029 0.0043 0.0325
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0084 0.0273 0.061
Schistosoma mansoni short chain dehydrogenase 0.002 0.0005 0.0006
Echinococcus granulosus ubiquitin specific peptidase 30 (C19 family) 0.0021 0.001 0.0011
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Brugia malayi intermediate filament protein 0.008 0.0258 0.0576
Schistosoma mansoni 3-keto-dihydrosphingosine reductase 0.002 0.0005 0.0006
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.0021 0.001 0.0077
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.001 0.0038
Loa Loa (eye worm) hypothetical protein 0.0031 0.0052 0.0116
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0129 0.0129
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0196 0.0748 0.1462
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0084 0.0273 0.061
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0031 0.0248
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.002 0.0005 0.0011
Echinococcus granulosus carbonyl reductase 1 0.002 0.0005 0.0006
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0363 0.145 0.145
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0029 0.0043 0.0078
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.001 0.0022
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 2, putative 0.0021 0.001 0.0077
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0005 0.0011
Trypanosoma cruzi cruzipain precursor, putative 0.0063 0.0184 0.1464
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0005 0.0011
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.001 0.0077
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0029 0.0043 0.0078
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Entamoeba histolytica hypothetical protein, conserved 0.002 0.0005 0.0013
Loa Loa (eye worm) glutathione reductase 0.0317 0.1259 0.2815
Trichomonas vaginalis conserved hypothetical protein 0.0137 0.0498 0.0972
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.011 0.0384 0.3048
Trypanosoma brucei glucosidase, putative 0.0076 0.0241 0.1917
Schistosoma mansoni caspase-7 (C14 family) 0.0265 0.1037 0.1187
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0076 0.0241 0.1344
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0125 0.0447 0.0512
Schistosoma mansoni cpg binding protein 0.0036 0.0072 0.0082
Loa Loa (eye worm) steroid hormone receptor 0.0084 0.0273 0.061
Brugia malayi hypothetical protein 0.0039 0.0086 0.0193
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.001 0.0077
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0039 0.0086 0.0086
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0005 0.0011
Loa Loa (eye worm) thioredoxin reductase 0.0317 0.1259 0.2815
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.001 0.0077
Plasmodium falciparum thioredoxin reductase 0.011 0.0384 0.3048
Loa Loa (eye worm) hypothetical protein 0.002 0.0005 0.0012
Schistosoma mansoni hypothetical protein 0.0041 0.0092 0.0105
Echinococcus multilocularis PHD finger protein rhinoceros 0.0059 0.0169 0.0169
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0096 0.0324 0.0371
Toxoplasma gondii histone lysine methyltransferase SET1 0.0069 0.0212 0.1681
Brugia malayi beta-lactamase 0.0111 0.0386 0.0864
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0003 0.0007
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0029 0.0043 0.0043
Onchocerca volvulus 0.0025 0.0024 0.0036
Brugia malayi hypothetical protein 0.0044 0.0106 0.0237
Leishmania major cathepsin L-like protease 0.0063 0.0184 0.1464
Echinococcus granulosus neuropeptide s receptor 0.0939 0.3881 0.4441
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.001 0.0077
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Echinococcus granulosus Niemann Pick C1 protein 0.0099 0.0337 0.0385
Loa Loa (eye worm) dehydrogenase 0.002 0.0005 0.0012
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0129 0.0248
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0021 0.001 0.0077
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.012 0.0269
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0114 0.0399 0.0399
Mycobacterium ulcerans monoxygenase 0.0029 0.0043 0.0178
Onchocerca volvulus 0.0029 0.0043 0.0073
Echinococcus multilocularis lysosomal alpha glucosidase 0.0344 0.137 0.137
Schistosoma mansoni family C19 unassigned peptidase (C19 family) 0.0021 0.001 0.0011
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0029 0.0043 0.0178
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.001 0.0013
Echinococcus multilocularis Protein lozenge 0.0054 0.0148 0.0148
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0028 0.0039 0.0067
Mycobacterium tuberculosis Probable oxidoreductase 0.0805 0.3315 1
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0005 0.0011
Echinococcus multilocularis carbonyl reductase 1 0.002 0.0005 0.0005
Plasmodium falciparum ubiquitin specific protease, putative 0.0021 0.001 0.0077
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0039 0.0086 0.0099
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0096 0.0324 0.0371
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0077 0.0244 0.6322
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0021 0.001 0.0077
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.002 0.0005 0.0043
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 4 0.0021 0.001 0.001
Echinococcus granulosus WW domain containing oxidoreductase 0.002 0.0005 0.0006
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0297 0.1172 0.9312
Trichomonas vaginalis alpha-glucosidase, putative 0.0076 0.0241 0.0468
Schistosoma mansoni DNA polymerase eta 0.002 0.0003 0.0003
Entamoeba histolytica hypothetical protein 0.0114 0.0399 0.2235
Brugia malayi Nuclear hormone receptor-like 1 0.0084 0.0273 0.061
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0077 0.0244 0.0729
Brugia malayi DKFZp564C0469 protein 0.0031 0.0052 0.0116
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0005 0.0007
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0029 0.0043 0.0178
Trypanosoma brucei beta-D-hydroxybutyrate dehydrogenase 0.002 0.0005 0.0043
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0363 0.145 0.1659
Giardia lamblia DUB-1 0.0021 0.001 0.009
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0076 0.0241 0.054
Trichomonas vaginalis Harbinger-1_Harbinger/PIFA2 transposable element protein 0.0021 0.001 0.0013
Trichomonas vaginalis conserved hypothetical protein 0.0137 0.0498 0.0972
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 47 0.0021 0.001 0.0011
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0196 0.0748 0.5943
Echinococcus multilocularis steroid dehydrogenase 0.002 0.0005 0.0005
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.017 0.0637 0.1425
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0031 0.0052 0.0276
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.002 0.0005 0.0011
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.011 0.0384 0.3048
Schistosoma mansoni hypothetical protein 0.0021 0.0009 0.001
Leishmania major alpha glucosidase II subunit, putative 0.0076 0.0241 0.1917
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.005 0.0132 0.0383
Trichomonas vaginalis apoptosis inducing factor, putative 0.0029 0.0043 0.0078
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0129 0.1026
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0029 0.0043 0.0533
Trypanosoma cruzi metacaspase, putative 0.0137 0.0498 0.396
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.011 0.0384 0.3048
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Trichomonas vaginalis short-chain dehydrogenase, putative 0.002 0.0005 0.0005
Echinococcus multilocularis expressed conserved protein 0.0093 0.0311 0.0311
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0099 0.0337 0.1882
Loa Loa (eye worm) TAR-binding protein 0.0657 0.269 0.6017
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Echinococcus granulosus thyroid hormone receptor alpha 0.0039 0.0086 0.0099
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0009 0.002
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0084 0.0273 0.0312
Trypanosoma cruzi oxidoreductase-like protein, putative 0.002 0.0005 0.0043
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0003 0.0024
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.001 0.0077
Trypanosoma brucei unspecified product 0.002 0.0003 0.0024
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0137 0.0498 0.0972
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.001 0.0013
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0297 0.1172 0.9312
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0077 0.0244 0.0279
Mycobacterium ulcerans NADH dehydrogenase 0.0029 0.0043 0.0178
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0084 0.0273 0.061
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0244 0.1937
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 4 0.0021 0.001 0.0011
Loa Loa (eye worm) oxidoreductase 0.002 0.0005 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0184 0.1464
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0084 0.0273 0.0312
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.001 0.0022
Echinococcus multilocularis FTZ F1 alpha 0.0084 0.0273 0.0273
Trypanosoma cruzi NADH dehydrogenase, putative 0.0029 0.0043 0.0339
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0805 0.3315 1
Schistosoma mansoni short chain dehydrogenase 0.002 0.0005 0.0006
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Echinococcus multilocularis Niemann Pick C1 protein 0.0099 0.0337 0.0337
Loa Loa (eye worm) hypothetical protein 0.0044 0.0106 0.0237
Mycobacterium tuberculosis Probable oxidoreductase 0.002 0.0005 0.0007
Brugia malayi follicle stimulating hormone receptor 0.0505 0.2052 0.4591
Echinococcus multilocularis Ubiquitin carboxyl terminal hydrolase 48 0.0021 0.001 0.001
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0084 0.0273 0.061
Echinococcus granulosus lysosomal alpha glucosidase 0.0344 0.137 0.1568
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.001 0.0038
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0029 0.0043 0.0339
Mycobacterium tuberculosis Possible short-chain dehydrogenase EphD 0.002 0.0005 0.0007
Trypanosoma cruzi 3-keto-dihydrosphingosine reductase 0.002 0.0005 0.0043
Loa Loa (eye worm) hypothetical protein 0.0044 0.0106 0.0237
Giardia lamblia Hypothetical protein 0.0021 0.001 0.009
Loa Loa (eye worm) hypothetical protein 0.0084 0.0273 0.061
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0052 0.0096
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0029 0.0043 0.012
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0039 0.0086 0.0099
Brugia malayi hypothetical protein 0.0066 0.0199 0.0445
Echinococcus multilocularis protein patched 0.0042 0.0099 0.0099
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0132 0.0295
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Leishmania major NADH dehydrogenase, putative 0.0029 0.0043 0.0339
Plasmodium falciparum ferrodoxin reductase-like protein 0.0029 0.0043 0.0339
Brugia malayi Hypothetical oxidoreductase F56D1.5 0.002 0.0005 0.0012
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0029 0.0043 0.0113
Loa Loa (eye worm) hypothetical protein 0.0059 0.0169 0.0378
Schistosoma mansoni coup transcription factor 0.0084 0.0273 0.0312
Schistosoma mansoni glutamate synthase 0.0029 0.0043 0.0049
Brugia malayi F/Y-rich N-terminus family protein 0.0037 0.0075 0.0167
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.0021 0.001 0.0077
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0005 0.0012
Leishmania major oxidoreductase-like protein 0.002 0.0005 0.0043
Brugia malayi Bromodomain containing protein 0.0039 0.0085 0.0191
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0724 0.2974 0.8971
Loa Loa (eye worm) hypothetical protein 0.0021 0.001 0.0022
Loa Loa (eye worm) oxidoreductase 0.002 0.0005 0.0012
Schistosoma mansoni ubiquitin-specific peptidase 14 (C19 family) 0.0021 0.001 0.0011
Trichomonas vaginalis replication factor C large subunit, putative 0.0031 0.0052 0.0096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Toxoplasma gondii ubiquitin carboxyl-terminal hydrolase 0.0021 0.001 0.0077
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Schistosoma mansoni zinc finger protein 0.0022 0.0012 0.0014
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0054
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.001 0.0038
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0344 0.137 0.3064
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 7 0.0021 0.001 0.001
Mycobacterium ulcerans short chain dehydrogenase 0.002 0.0005 0.0011
Loa Loa (eye worm) short chain dehydrogenase/reductase family oxidoreductase 0.002 0.0005 0.0012
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0084 0.0273 0.061
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0021 0.001 0.0038
Mycobacterium ulcerans dehydrogenase 0.002 0.0005 0.0011
Schistosoma mansoni steroid hormone receptor ad4bp 0.0084 0.0273 0.0312
Loa Loa (eye worm) hypothetical protein 0.0039 0.0083 0.0185
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0081 0.026 0.0582
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0029 0.0043 0.0178
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0029 0.0043 0.0113
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0039 0.0086 0.0193
Echinococcus granulosus Ubiquitin carboxyl terminal hydrolase 48 0.0021 0.001 0.0011
Echinococcus multilocularis lamin 0.008 0.0258 0.0258
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0196 0.0748 0.5943
Schistosoma mansoni nuclear receptor 0.0039 0.0086 0.0099
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Schistosoma mansoni hypothetical protein 0.0041 0.0092 0.0105
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0196 0.0748 0.4202
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Leishmania major short chain dehydrogenase/reductase, putative 0.002 0.0005 0.0043
Echinococcus multilocularis zinc finger protein 0.0022 0.0012 0.0012
Trypanosoma cruzi ubiquitin hydrolase, putative 0.0021 0.001 0.0077
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0005 0.0012
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0021 0.001 0.0022
Loa Loa (eye worm) hypothetical protein 0.0044 0.0106 0.0237
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.044 0.1776 1
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0021 0.001 0.0013
Schistosoma mansoni jumonji/arid domain-containing protein 0.0075 0.0237 0.0272
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.002 0.0005 0.0012
Entamoeba histolytica hypothetical protein 0.0031 0.0052 0.0276
Schistosoma mansoni steroid dehydrogenase 0.002 0.0005 0.0006
Loa Loa (eye worm) hypothetical protein 0.0025 0.0024 0.0054

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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