Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | histone deacetylase, putative | 0.0444 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase 8 | 0.0127 | 0.1999 | 0.1999 |
Toxoplasma gondii | histone deacetylase HDAC4 | 0.0127 | 0.1999 | 0.0909 |
Echinococcus multilocularis | endothelin converting enzyme 1 | 0.0095 | 0.1199 | 0.1199 |
Brugia malayi | Peptidase family M13 containing protein | 0.0095 | 0.1199 | 0.1199 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.1999 | 0.1999 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0127 | 0.1999 | 0.1999 |
Entamoeba histolytica | histone deacetylase, putative | 0.0444 | 1 | 0.5 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0444 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1199 | 0.1199 |
Plasmodium vivax | histone deacetylase 1, putative | 0.0444 | 1 | 1 |
Schistosoma mansoni | histone deacetylase | 0.0444 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.028 | 0.5871 | 0.5871 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0444 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.028 | 0.5871 | 0.5871 |
Echinococcus multilocularis | acetylcholinesterase | 0.028 | 0.5871 | 0.5871 |
Echinococcus granulosus | histone deacetylase 6 | 0.0127 | 0.1999 | 0.1999 |
Brugia malayi | Hypothetical zinc metalloproteinase T16A9.4 | 0.0095 | 0.1199 | 0.1199 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.0444 | 1 | 1 |
Echinococcus granulosus | histone deacetylase 1 | 0.0444 | 1 | 1 |
Echinococcus granulosus | histone deacetylase 8 | 0.0127 | 0.1999 | 0.1999 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.007 | 0.0575 | 0.0575 |
Echinococcus granulosus | histone deacetylase | 0.0127 | 0.1999 | 0.1999 |
Brugia malayi | Histone deacetylase family protein | 0.0127 | 0.1999 | 0.1999 |
Loa Loa (eye worm) | carboxylesterase | 0.028 | 0.5871 | 0.5871 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0127 | 0.1999 | 0.1999 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0444 | 1 | 1 |
Giardia lamblia | Histone deacetylase | 0.0444 | 1 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.028 | 0.5871 | 0.5871 |
Brugia malayi | Histone deacetylase 1 | 0.0444 | 1 | 1 |
Mycobacterium leprae | probable zinc metalloprotease | 0.0095 | 0.1199 | 0.5 |
Loa Loa (eye worm) | histone deacetylase | 0.0127 | 0.1999 | 0.1999 |
Loa Loa (eye worm) | histone deacetylase 11 | 0.0127 | 0.1999 | 0.1999 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.0127 | 0.1999 | 0.1999 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.007 | 0.0575 | 0.0575 |
Echinococcus granulosus | endothelin converting enzyme 1 | 0.0095 | 0.1199 | 0.1199 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0616 | 0.0616 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.0444 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0444 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0444 | 1 | 1 |
Brugia malayi | Histone deacetylase family protein | 0.0127 | 0.1999 | 0.1999 |
Leishmania major | histone deacetylase, putative | 0.0444 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0444 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase 1 | 0.0444 | 1 | 1 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0095 | 0.1199 | 0.1199 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0444 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase 7 | 0.0127 | 0.1999 | 0.1999 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.0444 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase 3 | 0.0444 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.028 | 0.5871 | 0.5871 |
Mycobacterium tuberculosis | Probable zinc metalloprotease Zmp1 | 0.0095 | 0.1199 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0575 | 0.0575 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0444 | 1 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0444 | 1 | 1 |
Schistosoma mansoni | family M13 non-peptidase homologue (M13 family) | 0.0048 | 0.0014 | 0.0014 |
Schistosoma mansoni | neprilysin-2 (M13 family) | 0.0048 | 0.0014 | 0.0014 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0127 | 0.1999 | 0.1999 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0575 | 0.0575 |
Schistosoma mansoni | histone deacetylase 1 2 3 | 0.0127 | 0.1999 | 0.1999 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0616 | 0.0616 |
Toxoplasma gondii | histone deacetylase HDAC5 | 0.0127 | 0.1999 | 0.0909 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1199 | 0.1199 |
Plasmodium falciparum | histone deacetylase 1 | 0.0444 | 1 | 1 |
Trypanosoma brucei | histone deacetylase 1 | 0.0444 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 0.5871 | 0.5871 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0127 | 0.1999 | 0.1999 |
Echinococcus granulosus | acetylcholinesterase | 0.028 | 0.5871 | 0.5871 |
Onchocerca volvulus | Histone deacetylase 10 homolog | 0.0127 | 0.1999 | 1 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.0444 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0616 | 0.0616 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0444 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.028 | 0.5871 | 0.5871 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0575 | 0.0575 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1199 | 0.1199 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.028 | 0.5871 | 0.5871 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0127 | 0.1999 | 0.1999 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 0.5871 | 0.5871 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0616 | 0.0616 |
Echinococcus granulosus | histone deacetylase 3 | 0.0444 | 1 | 1 |
Schistosoma mansoni | histone deacetylase | 0.0444 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase | 0.0127 | 0.1999 | 0.1999 |
Echinococcus multilocularis | carboxylesterase 5A | 0.028 | 0.5871 | 0.5871 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0444 | 1 | 1 |
Brugia malayi | histone deacetylase 11 | 0.0127 | 0.1999 | 0.1999 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0048 | 0.0014 | 0.0014 |
Schistosoma mansoni | Nep2 peptidase (M13 family) | 0.0048 | 0.0014 | 0.0014 |
Echinococcus granulosus | carboxylesterase 5A | 0.028 | 0.5871 | 0.5871 |
Echinococcus granulosus | histone deacetylase 6 | 0.0127 | 0.1999 | 0.1999 |
Echinococcus granulosus | histone deacetylase 6 | 0.0127 | 0.1999 | 0.1999 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0616 | 0.0616 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0048 | 0.0014 | 0.0014 |
Mycobacterium ulcerans | zinc metalloprotease | 0.0095 | 0.1199 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0616 | 0.0616 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0127 | 0.1999 | 0.1999 |
Echinococcus granulosus | histone deacetylase 7 | 0.0127 | 0.1999 | 0.1999 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.0127 | 0.1999 | 0.0909 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0127 | 0.1999 | 0.1999 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.0444 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0575 | 0.0575 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0444 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.