Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0896 | 0.0896 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 1 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0896 | 0.0873 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.8902 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 1 | 1 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.3828 | 0.3828 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.0896 | 0.0873 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0896 | 0.0896 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.3828 | 0.3828 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.0896 | 0.0873 |
Echinococcus multilocularis | lamin | 0.0028 | 0.3828 | 0.4215 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.5786 | 0.5786 |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 0.3828 | 0.4215 |
Brugia malayi | intermediate filament protein | 0.0028 | 0.3828 | 0.3496 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0896 | 0.0873 |
Onchocerca volvulus | 0.0028 | 0.3828 | 0.5 | |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.0896 | 0.0873 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.8902 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0896 | 0.0407 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.0896 | 0.0873 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.8902 | 0.8843 |
Echinococcus granulosus | lamin | 0.0028 | 0.3828 | 0.4215 |
Onchocerca volvulus | 0.0028 | 0.3828 | 0.5 | |
Schistosoma mansoni | lamin | 0.0028 | 0.3828 | 0.3662 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.3828 | 0.3828 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.3697 | 0.3697 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 0.3828 | 0.3496 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.8902 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.5786 | 0.6108 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.5786 | 0.556 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 1 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0896 | 0.0407 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.8902 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.8902 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.8902 | 0.8902 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0131 | 0.0131 |
Schistosoma mansoni | lamin | 0.0028 | 0.3828 | 0.3662 |
Echinococcus multilocularis | musashi | 0.0028 | 0.3828 | 0.4215 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.051 | 0.051 |
Echinococcus granulosus | lamin dm0 | 0.0028 | 0.3828 | 0.4215 |
Schistosoma mansoni | intermediate filament proteins | 0.0028 | 0.3828 | 0.3662 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.8902 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 0.3828 | 0.4215 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.8902 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.