Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0051 | 0.5662 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0191 | 0.0242 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0051 | 0.5662 | 0.5 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0051 | 0.5662 | 0.6054 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.9228 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.5662 | 0.5 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.006 | 0.724 | 1 |
Brugia malayi | MAP kinase sur-1 | 0.0051 | 0.5662 | 0.52 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.2951 | 0.4076 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0023 | 0.0535 | 0.0739 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.5662 | 0.5 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0051 | 0.5662 | 0.782 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0051 | 0.5662 | 0.5 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0051 | 0.5662 | 0.5 |
Trypanosoma brucei | protein kinase, putative | 0.0051 | 0.5662 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.4163 | 0.4395 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.3391 | 0.3541 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.2951 | 0.4076 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0051 | 0.5662 | 0.5 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0051 | 0.5662 | 0.5 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0051 | 0.5662 | 0.5 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.0535 | 0.0679 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0051 | 0.5662 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0051 | 0.5662 | 0.718 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.5662 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.3818 | 0.4014 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.3378 | 0.2673 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0051 | 0.5662 | 0.782 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0051 | 0.5662 | 0.5 |
Schistosoma mansoni | bromodomain containing protein | 0.0063 | 0.7886 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0051 | 0.5662 | 0.782 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0023 | 0.0535 | 0.0739 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.006 | 0.724 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0051 | 0.5662 | 0.782 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.5662 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.