Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0034 | 0.0864 | 0.0864 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0132 | 0.4612 | 0.4612 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0034 | 0.0864 | 0.0864 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0034 | 0.0864 | 0.0864 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.008 | 0.2608 | 0.2608 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0157 | 0.5561 | 0.5561 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0864 | 0.1554 |
Schistosoma mansoni | survival motor neuron protein | 0.0056 | 0.1684 | 0.3028 |
Schistosoma mansoni | hypothetical protein | 0.0074 | 0.2385 | 0.4288 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.008 | 0.2608 | 0.2608 |
Brugia malayi | hypothetical protein | 0.008 | 0.2608 | 0.2608 |
Echinococcus granulosus | GPCR family 2 | 0.0034 | 0.0864 | 0.0864 |
Onchocerca volvulus | 0.0056 | 0.1684 | 1 | |
Schistosoma mansoni | transcription factor LCR-F1 | 0.008 | 0.2608 | 0.4689 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0864 | 0.1554 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0864 | 0.1554 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0108 | 0.3695 | 0.3695 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0108 | 0.3695 | 0.3695 |
Echinococcus multilocularis | GPCR, family 2 | 0.0034 | 0.0864 | 0.0864 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0273 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0864 | 0.0864 |
Entamoeba histolytica | hypothetical protein | 0.008 | 0.2608 | 0.5 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0273 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0146 | 0.5115 | 0.9197 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0034 | 0.0864 | 0.0864 |
Entamoeba histolytica | hypothetical protein | 0.008 | 0.2608 | 0.5 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0034 | 0.0864 | 0.0864 |
Entamoeba histolytica | hypothetical protein | 0.008 | 0.2608 | 0.5 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0146 | 0.5115 | 0.5115 |
Schistosoma mansoni | hypothetical protein | 0.008 | 0.2608 | 0.4689 |
Brugia malayi | MH2 domain containing protein | 0.0132 | 0.4612 | 0.4612 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.2385 | 0.2385 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0074 | 0.2385 | 0.2385 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0864 | 0.1554 |
Loa Loa (eye worm) | hypothetical protein | 0.0273 | 1 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0108 | 0.3695 | 0.3695 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0034 | 0.0864 | 0.0864 |
Schistosoma mansoni | thyroid hormone receptor | 0.0157 | 0.5561 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0132 | 0.4612 | 0.4612 |
Schistosoma mansoni | thyroid hormone receptor | 0.0157 | 0.5561 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0034 | 0.0864 | 0.0864 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0146 | 0.5115 | 0.5115 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0056 | 0.1684 | 0.1684 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.3695 | 0.3695 |
Entamoeba histolytica | hypothetical protein | 0.008 | 0.2608 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0056 | 0.1684 | 0.3028 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.