Detailed information for compound 631263

Basic information

Technical information
  • TDR Targets ID: 631263
  • Name: N-(3,5-dimethylphenyl)-2-phenylbutanamide
  • MW: 267.365 | Formula: C18H21NO
  • H donors: 1 H acceptors: 1 LogP: 4.35 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCC(C(=O)Nc1cc(C)cc(c1)C)c1ccccc1
  • InChi: 1S/C18H21NO/c1-4-17(15-8-6-5-7-9-15)18(20)19-16-11-13(2)10-14(3)12-16/h5-12,17H,4H2,1-3H3,(H,19,20)
  • InChiKey: OUUUQAYAQHXCCV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(3,5-dimethylphenyl)-2-phenyl-butanamide
  • N-(3,5-dimethylphenyl)-2-phenyl-butyramide
  • AK-968/11369005

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0084 0.0424 0.3321
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0309 0.1725 1
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0064 0.0308 0.097
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0037 0.0154
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0037 0.094
Mycobacterium ulcerans esterase/lipase LipP 0.004 0.0166 0.1537
Echinococcus granulosus transcription factor btf3 0.0036 0.0144 0.0311
Toxoplasma gondii ABC1 family protein 0.004 0.0166 0.3919
Brugia malayi Carboxylesterase family protein 0.0095 0.0484 0.1521
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0011 0.000000000023893 0.000000000051474
Leishmania major mitochondrial DNA polymerase beta 0.0309 0.1725 1
Plasmodium falciparum glutathione reductase 0.0017 0.0037 0.094
Mycobacterium ulcerans hypothetical protein 0.004 0.0166 0.1537
Brugia malayi chromobox protein homolog 3 0.0038 0.0156 0.0491
Mycobacterium ulcerans beta-lactamase 0.004 0.0166 0.1537
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0035 0.0111
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0115 0.0603 0.4123
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0031 0.0777
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0753 0.1623
Loa Loa (eye worm) hypothetical protein 0.004 0.0166 0.0523
Trypanosoma brucei hypothetical protein, conserved 0.004 0.0166 0.0908
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0045 0.0355
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0187 0.103
Loa Loa (eye worm) hypothetical protein 0.0095 0.0484 0.1521
Loa Loa (eye worm) hypothetical protein 0.0095 0.0484 0.1521
Loa Loa (eye worm) hypothetical protein 0.0079 0.0393 0.1236
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0037 0.0289
Schistosoma mansoni tar DNA-binding protein 0.0202 0.1108 0.2386
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0013 0.001 0.0032
Echinococcus multilocularis chromobox protein 1 0.0068 0.0329 0.0329
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0045 0.0203
Loa Loa (eye worm) jmjC domain-containing protein 0.0059 0.0276 0.0867
Trypanosoma brucei transcription factor BTF3, putative 0.0036 0.0144 0.078
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0076 0.0595
Brugia malayi beta-lactamase family protein 0.004 0.0166 0.0523
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0075 0.0373 0.2449
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0559 0.3179 0.6849
Echinococcus multilocularis neuropeptide s receptor 0.0473 0.2675 0.2675
Brugia malayi SET domain containing protein 0.0013 0.001 0.0031
Schistosoma mansoni acetylcholinesterase 0.0095 0.0484 0.1042
Echinococcus multilocularis zinc finger protein 0.0021 0.0055 0.0055
Brugia malayi jmjC domain containing protein 0.0093 0.0475 0.1493
Brugia malayi Carboxylesterase family protein 0.0559 0.3179 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0254 0.1409 1
Plasmodium vivax SET domain protein, putative 0.003 0.0108 0.2741
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0141 0.0753 0.237
Loa Loa (eye worm) hypothetical protein 0.0056 0.026 0.0819
Schistosoma mansoni sex comb on midleg homolog 0.0094 0.0483 0.1041
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.01 0.2364
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.01 0.0515 0.111
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0032 0.0069
Mycobacterium tuberculosis Probable hydrolase 0.004 0.0166 0.0942
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0064 0.0308 0.0664
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0108 0.0232
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0052 0.0235 0.1446
Mycobacterium tuberculosis Probable dehydrogenase 0.0115 0.0603 0.4123
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0041 0.0172 0.0371
Onchocerca volvulus 0.004 0.0166 0.1302
Echinococcus granulosus Chromobox protein 3 0.0011 0.0000000070601 0.00000001521
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0223 0.0481
Loa Loa (eye worm) thioredoxin reductase 0.005 0.0228 0.0717
Trypanosoma cruzi ISWI complex protein 0.0015 0.0022 0.0066
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.004 0.0166 0.0942
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0011 0.000000000023893 0.00000000056348
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0064 0.0306 0.1964
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.000000000023893 0.00000000018715
Schistosoma mansoni hypothetical protein 0.01 0.0515 0.111
Brugia malayi Heterochromatin protein 1 0.0068 0.0329 0.1035
Schistosoma mansoni gliotactin 0.0095 0.0484 0.1042
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0115 0.0603 0.8725
Brugia malayi MAP kinase sur-1 0.005 0.0223 0.0702
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0092 0.0719
Echinococcus multilocularis para nitrobenzyl esterase 0.0095 0.0484 0.0484
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0076 0.0595
Echinococcus multilocularis thioredoxin glutathione reductase 0.005 0.0228 0.0228
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0037 0.008
Brugia malayi MH2 domain containing protein 0.0135 0.0719 0.2262
Echinococcus multilocularis BC026374 protein (S09 family) 0.0095 0.0484 0.0484
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0037 0.0154
Trichomonas vaginalis inositol monophosphatase, putative 0.0084 0.0424 0.3321
Loa Loa (eye worm) RNA binding protein 0.0202 0.1108 0.3484
Schistosoma mansoni transcription factor btf3 0.0036 0.0144 0.0311
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0155 0.0487
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.0753 0.0753
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0011 0.000000000023893 0.000000000023893
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0011 0.000000000023893 0.00000000060813
Echinococcus multilocularis acetylcholinesterase 0.0559 0.3179 0.3179
Schistosoma mansoni cpg binding protein 0.0028 0.0098 0.0211
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0045 0.0451
Brugia malayi Bromodomain containing protein 0.0075 0.0368 0.1159
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0079 0.0393 0.0393
Brugia malayi Thioredoxin reductase 0.005 0.0228 0.0717
Loa Loa (eye worm) hypothetical protein 0.0049 0.0218 0.0685
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0072 0.0155
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0029 0.0693
Plasmodium vivax hypothetical protein, conserved 0.0011 0.000000000023893 0.00000000060813
Echinococcus multilocularis cpg binding protein 0.0031 0.0118 0.0118
Mycobacterium tuberculosis Probable lipase LipE 0.004 0.0166 0.0942
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.000000000023893 0.00000000018715
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0173 0.1354
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0108 0.254
Brugia malayi CHD4 protein 0.0015 0.002 0.0063
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0064 0.0306 0.1725
Brugia malayi Pre-SET motif family protein 0.003 0.0108 0.0339
Schistosoma mansoni peptidase Clp (S14 family) 0.0079 0.0393 0.0846
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.002 0.0154
Trichomonas vaginalis spcc417.12 protein, putative 0.0095 0.0484 0.3789
Echinococcus granulosus dnaJ subfamily B 0.0398 0.2245 0.4837
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0187 0.103
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.01 0.01
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0753 0.1623
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0093 0.2371
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.01 0.0315
Schistosoma mansoni hypothetical protein 0.0015 0.0022 0.0047
Echinococcus granulosus cpg binding protein 0.0031 0.0118 0.0254
Trypanosoma brucei ISWI complex protein 0.0015 0.0022 0.0066
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0045 0.0203
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0155 0.0334
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0037 0.0154
Schistosoma mansoni jumonji domain containing protein 0.0074 0.0364 0.0784
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0115 0.0603 0.4123
Echinococcus multilocularis microtubule associated protein 2 0.0812 0.4642 0.4642
Plasmodium falciparum basic transcription factor 3b, putative 0.0036 0.0144 0.3671
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0146 0.0782 0.4502
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0203 0.1114 0.3505
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0128 0.0677 1
Loa Loa (eye worm) hypothetical protein 0.004 0.0166 0.0523
Brugia malayi jmjC domain containing protein 0.0038 0.0155 0.0487
Brugia malayi Carboxylesterase family protein 0.0559 0.3179 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0046 0.0204 0.0439
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0076 0.0076
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0045 0.0203
Schistosoma mansoni hypothetical protein 0.0357 0.2005 0.4319
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.01 0.0515 0.0515
Loa Loa (eye worm) hypothetical protein 0.0095 0.0484 0.1521
Loa Loa (eye worm) hypothetical protein 0.004 0.0166 0.0523
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0286 0.0616
Schistosoma mansoni cellular tumor antigen P53 0.0056 0.026 0.0561
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0046 0.0204 0.0204
Loa Loa (eye worm) carboxylesterase 0.0095 0.0484 0.1521
Plasmodium falciparum glutathione reductase 0.005 0.0228 0.5803
Schistosoma mansoni inositol monophosphatase 0.0084 0.0424 0.0914
Brugia malayi beta-lactamase family protein 0.004 0.0166 0.0523
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0166 0.1302
Onchocerca volvulus 0.0056 0.026 0.2039
Loa Loa (eye worm) hypothetical protein 0.003 0.0108 0.0341
Echinococcus granulosus microtubule associated protein 2 0.0812 0.4642 1
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0393 0.9266
Loa Loa (eye worm) hypothetical protein 0.0095 0.0484 0.1521
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.000000000023893 0.00000000056348
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.006 0.0282 0.0607
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0166 0.1302
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0376 0.2116 0.2116
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0144 0.113
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0223 0.1749
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0037 0.0154
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0037 0.0154
Schistosoma mansoni inositol monophosphatase 0.0084 0.0424 0.0914
Toxoplasma gondii thioredoxin reductase 0.005 0.0228 0.5377
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0064 0.0308 0.097
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0084 0.0424 0.2412
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0316 0.1768 0.556
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0045 0.0143
Entamoeba histolytica recQ family helicase, putative 0.0013 0.0011 0.025
Onchocerca volvulus 0.0095 0.0484 0.3789
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0056 0.0176
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.01 0.0515 0.1621
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0753 0.1623
Trypanosoma cruzi transcription factor btf3, putative 0.0036 0.0144 0.078
Brugia malayi Bromodomain containing protein 0.0037 0.0152 0.0478
Onchocerca volvulus 0.0095 0.0484 0.3789
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0098 0.0211
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0064 0.0308 0.7272
Brugia malayi Associated with TFs and helicases family protein 0.0011 0.000000000023893 0.000000000075153
Mycobacterium tuberculosis Probable oxidoreductase 0.0128 0.0677 0.4666
Plasmodium vivax glutathione reductase, putative 0.005 0.0228 0.5803
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0128 0.0677 0.4666
Mycobacterium ulcerans hypothetical protein 0.0163 0.0878 1
Echinococcus granulosus para nitrobenzyl esterase 0.0095 0.0484 0.1042
Brugia malayi Bromodomain containing protein 0.0031 0.0114 0.0357
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0015 0.002 0.002
Plasmodium falciparum thioredoxin reductase 0.005 0.0228 0.5803
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0084 0.0424 1
Schistosoma mansoni microtubule-associated protein tau 0.0812 0.4642 1
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0084 0.0424 1
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0037 0.0871
Mycobacterium tuberculosis Probable lipase LipD 0.004 0.0166 0.0942
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0084 0.0424 0.4602
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0037 0.094
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0037 0.0871
Echinococcus multilocularis histone acetyltransferase MYST2 0.0108 0.0559 0.0559
Schistosoma mansoni cpg binding protein 0.0031 0.0118 0.0254
Echinococcus multilocularis carboxylesterase 5A 0.0559 0.3179 0.3179
Schistosoma mansoni hypothetical protein 0.002 0.0052 0.0112
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0141 0.0753 0.237
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0094 0.0483 0.1041
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0036 0.0077
Loa Loa (eye worm) hypothetical protein 0.0094 0.0483 0.152
Echinococcus multilocularis dnaJ subfamily B 0.0398 0.2245 0.2245
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0037 0.0288
Schistosoma mansoni tar DNA-binding protein 0.0202 0.1108 0.2386
Brugia malayi Probable ClpP-like protease 0.0079 0.0393 0.1236
Echinococcus multilocularis acetylcholinesterase 0.0559 0.3179 0.3179
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.0753 0.1623
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0393 1
Loa Loa (eye worm) hypothetical protein 0.0559 0.3179 1
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0093 0.158
Echinococcus granulosus histone acetyltransferase MYST2 0.0108 0.0559 0.1204
Schistosoma mansoni sex comb on midleg homolog 0.0094 0.0483 0.1041
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0059 0.15
Loa Loa (eye worm) MH2 domain-containing protein 0.0135 0.0719 0.2262
Onchocerca volvulus 0.0011 0.0000000070601 0.000000055302
Echinococcus multilocularis transcription factor btf3 0.0036 0.0144 0.0144
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0032 0.0069
Mycobacterium tuberculosis Conserved hypothetical protein 0.0163 0.0878 0.6132
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0166 0.1302
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0223 0.1241
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0306 0.3203
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0098 0.0308
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0037 0.0288
Loa Loa (eye worm) hypothetical protein 0.0108 0.0559 0.1758
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0037 0.0154
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0046 0.0204 0.0439
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0079 0.0393 1
Mycobacterium tuberculosis Probable reductase 0.0115 0.0603 0.4123
Schistosoma mansoni BC026374 protein (S09 family) 0.0095 0.0484 0.1042
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0146 0.0782 0.4502
Leishmania major basic transcription factor 3a, putative 0.0036 0.0144 0.078
Onchocerca volvulus 0.0231 0.1277 1
Loa Loa (eye worm) glutathione reductase 0.005 0.0228 0.0717
Schistosoma mansoni myelin transcription factor 1 myt1 0.0108 0.0559 0.1204
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0115 0.0603 0.4123
Echinococcus granulosus thioredoxin glutathione reductase 0.005 0.0228 0.0491
Onchocerca volvulus 0.004 0.0166 0.1302
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0115 0.0603 0.4123
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0306 0.3203
Echinococcus multilocularis chromobox protein 1 0.0068 0.0329 0.0329
Plasmodium vivax hypothetical protein, conserved 0.0028 0.01 0.2551
Brugia malayi PHD-finger family protein 0.0028 0.01 0.0315
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0166 0.0908
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0108 0.0108
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0095 0.0484 0.1042
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0155 0.0334
Trichomonas vaginalis D-aminoacylase, putative 0.004 0.0166 0.1302
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0223 0.1749
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0076 0.0239
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0037 0.0288
Echinococcus granulosus tumor protein p63 0.0383 0.2154 0.464
Mycobacterium tuberculosis Probable conserved lipoprotein 0.004 0.0166 0.0942
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0045 0.1154
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0329 0.2577
Loa Loa (eye worm) hypothetical protein 0.0095 0.0484 0.1521
Loa Loa (eye worm) hypothetical protein 0.0216 0.1188 0.3737
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0223 0.0481
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0308 0.1737
Echinococcus multilocularis SAM and MBT domain containing protein 0.0094 0.0483 0.0483
Loa Loa (eye worm) hypothetical protein 0.0011 0.000000000023893 0.000000000075153
Mycobacterium leprae Probable lipase LipE 0.004 0.0166 0.1251
Loa Loa (eye worm) hypothetical protein 0.0122 0.0642 0.202
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0015 0.002 0.0043
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.0753 0.0753
Echinococcus granulosus inositol monophosphatase 1 0.0084 0.0424 0.0914
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0011 0.000000000023893 0.000000000075153
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0329 0.1035
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0144 0.113
Echinococcus granulosus acetylcholinesterase 0.0559 0.3179 0.6849
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0072 0.0072
Trypanosoma brucei trypanothione reductase 0.005 0.0228 0.1268
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0223 0.1241
Brugia malayi mbt repeat family protein 0.0094 0.0483 0.152
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0095 0.0484 0.3789
Schistosoma mansoni tar DNA-binding protein 0.0202 0.1108 0.2386
Loa Loa (eye worm) hypothetical protein 0.0069 0.0335 0.1054
Onchocerca volvulus 0.0095 0.0484 0.3789
Echinococcus granulosus carboxylesterase 5A 0.0559 0.3179 0.6849
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0046 0.01
Brugia malayi Latrophilin receptor protein 2 0.01 0.0515 0.1621
Loa Loa (eye worm) hypothetical protein 0.0037 0.0152 0.0479
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0037 0.0154
Echinococcus granulosus bloom syndrome protein 0.0024 0.0076 0.0164
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0223 0.0223
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0108 0.0559 0.1204
Plasmodium falciparum phd finger protein, putative 0.0028 0.01 0.2551
Echinococcus granulosus chromobox protein 1 0.0068 0.0329 0.0709
Loa Loa (eye worm) mbt repeat family protein 0.0094 0.0483 0.152
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.004 0.0166 0.0523
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0013 0.0009 0.0009
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0223 0.1241
Loa Loa (eye worm) latrophilin receptor protein 2 0.01 0.0515 0.1621
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.01 0.0216
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0064 0.0308 0.1737
Brugia malayi Pre-SET motif family protein 0.0203 0.1114 0.3505
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0064 0.0306 0.0306
Mycobacterium tuberculosis Carboxylesterase LipT 0.0095 0.0484 0.3257
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0223 0.0223
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0308 0.1737
Schistosoma mansoni hypothetical protein 0.01 0.0515 0.111
Echinococcus multilocularis beta LACTamase domain containing family member 0.004 0.0166 0.0166
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0166 0.0358
Entamoeba histolytica hypothetical protein 0.0036 0.0144 0.3402
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0064 0.0306 0.066
Loa Loa (eye worm) hypothetical protein 0.004 0.0166 0.0523
Trypanosoma cruzi hypothetical protein, conserved 0.004 0.0166 0.0908
Loa Loa (eye worm) hypothetical protein 0.0095 0.0484 0.1521
Loa Loa (eye worm) RecQ helicase 0.0024 0.0076 0.0239
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0095 0.0484 0.1042
Schistosoma mansoni chromobox protein 0.0068 0.0329 0.0709
Toxoplasma gondii NAC domain-containing protein 0.0036 0.0144 0.3402
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.000000000023893 0.00000000056348
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0173 0.1354
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0037 0.0154
Trichomonas vaginalis set domain proteins, putative 0.0231 0.1277 1
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.0393 0.9266
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0094 0.0483 0.3785
Loa Loa (eye worm) acetylcholinesterase 1 0.0559 0.3179 1
Loa Loa (eye worm) carboxylesterase 0.0095 0.0484 0.1521
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0037 0.0154
Loa Loa (eye worm) TAR-binding protein 0.0202 0.1108 0.3484
Trypanosoma brucei protein kinase, putative 0.005 0.0223 0.1241
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0223 0.1241
Entamoeba histolytica hypothetical protein 0.0011 0.000000000023893 0.00000000056348
Loa Loa (eye worm) hypothetical protein 0.0013 0.0009 0.003
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0223 0.1241
Loa Loa (eye worm) hypothetical protein 0.0043 0.0186 0.0584
Brugia malayi TAR-binding protein 0.0202 0.1108 0.3484
Echinococcus granulosus lysine specific demethylase 5A 0.0038 0.0155 0.0334
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.000000000023893 0.00000000018715
Echinococcus granulosus jumonji domain containing protein 0.004 0.0165 0.0355
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.01 0.0515 0.111
Toxoplasma gondii hypothetical protein 0.0027 0.0093 0.2197
Echinococcus multilocularis tumor protein p63 0.0383 0.2154 0.2154
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.0393 1
Brugia malayi RNA binding protein 0.0202 0.1108 0.3484
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0013 0.001 0.0032
Echinococcus granulosus chromobox protein 1 0.0068 0.0329 0.0709
Echinococcus granulosus Chromo domain 0.0011 0.000000000023893 0.000000000051474
Loa Loa (eye worm) beta-lactamase 0.004 0.0166 0.0523
Loa Loa (eye worm) hypothetical protein 0.0095 0.0484 0.1521
Toxoplasma gondii hypothetical protein 0.005 0.0224 0.5287
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0045 0.0217
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0093 0.0475 0.0475
Loa Loa (eye worm) hypothetical protein 0.004 0.0166 0.0521
Echinococcus multilocularis geminin 0.0357 0.2005 0.2005
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.0393 1
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0079 0.0393 0.9196
Schistosoma mansoni hypothetical protein 0.01 0.0515 0.111
Mycobacterium tuberculosis Probable esterase LipL 0.004 0.0166 0.0942
Brugia malayi Carboxylesterase family protein 0.0095 0.0484 0.1521
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0144 0.113
Echinococcus multilocularis Chromobox protein 3 0.0011 0.0000000070601 0.0000000070601
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0156 0.1223
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0092 0.0719
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0052 0.0235 0.1446
Toxoplasma gondii PHD-finger domain-containing protein 0.0028 0.01 0.2364
Onchocerca volvulus Alhambra homolog 0.0028 0.01 0.0785
Brugia malayi RNA recognition motif domain containing protein 0.0202 0.1108 0.3484
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0037 0.0288
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0037 0.0154
Leishmania major hypothetical protein, conserved 0.0015 0.0022 0.0066
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0306 0.066
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0262 0.6188
Loa Loa (eye worm) hypothetical protein 0.0038 0.0156 0.0491
Schistosoma mansoni hypothetical protein 0.0216 0.1188 0.2559
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0064 0.0308 0.0308
Loa Loa (eye worm) transcription factor SMAD2 0.0135 0.0719 0.2262
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0108 0.0559 0.1758
Brugia malayi latrophilin 2 splice variant baaae 0.0216 0.1188 0.3737
Leishmania major trypanothione reductase 0.005 0.0228 0.1268
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0223 0.5267
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0045 0.01
Loa Loa (eye worm) hypothetical protein 0.004 0.0166 0.0523
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0032 0.0032
Trichomonas vaginalis penicillin-binding protein, putative 0.004 0.0166 0.1302
Echinococcus granulosus polycomb protein SCMH1 0.0094 0.0483 0.1041
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0095 0.0484 0.3257
Loa Loa (eye worm) hypothetical protein 0.004 0.0166 0.0523
Loa Loa (eye worm) hypothetical protein 0.0559 0.3179 1
Trichomonas vaginalis DNA helicase recq, putative 0.0013 0.0011 0.0083
Loa Loa (eye worm) MBCTL1 0.0108 0.0559 0.1758
Brugia malayi hypothetical protein 0.0095 0.0484 0.1521
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.01 0.0216
Leishmania major hypothetical protein, conserved 0.004 0.0166 0.0908
Brugia malayi Inositol-1 0.0084 0.0424 0.1334
Plasmodium falciparum thioredoxin reductase 0.0017 0.0037 0.094
Schistosoma mansoni hypothetical protein 0.0398 0.2245 0.4837
Toxoplasma gondii aldehyde dehydrogenase 0.0064 0.0306 0.7225
Plasmodium vivax basic transcription factor 3b, putative 0.0036 0.0144 0.3671
Mycobacterium tuberculosis Conserved protein 0.004 0.0166 0.0942
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0329 0.2577
Trichomonas vaginalis esterase, putative 0.004 0.0166 0.1302
Onchocerca volvulus 0.0094 0.0483 0.3785
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0223 0.1749
Plasmodium vivax thioredoxin reductase, putative 0.005 0.0228 0.5803
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0095 0.0484 0.1042
Onchocerca volvulus 0.0028 0.0098 0.0766
Loa Loa (eye worm) carboxylesterase 0.0559 0.3179 1
Schistosoma mansoni hypothetical protein 0.01 0.0515 0.111
Loa Loa (eye worm) hypothetical protein 0.0046 0.0204 0.0642
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0037 0.0154
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0045 0.0061
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0187 0.103
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0165 0.0165
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0309 0.1725 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0045 0.0203
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0156 0.1223
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0045 0.0045
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0202 0.1108 0.3484
Mycobacterium ulcerans aldehyde dehydrogenase 0.0064 0.0306 0.3203
Brugia malayi Carboxylesterase family protein 0.0095 0.0484 0.1521
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0037 0.0116
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0075 0.0373 0.4791
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.000000000023893 0.00000000056348
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0079 0.0393 1
Onchocerca volvulus 0.003 0.0108 0.085
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0173 0.1354
Schistosoma mansoni bromodomain containing protein 0.0063 0.0302 0.0651
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0079 0.0393 0.0846
Echinococcus granulosus neuropeptide s receptor 0.0473 0.2675 0.5763
Echinococcus multilocularis lysine specific demethylase 5A 0.0034 0.0135 0.0135
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0045 0.0143
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0052 0.0164
Brugia malayi CXXC zinc finger family protein 0.0028 0.0098 0.0308
Echinococcus granulosus BC026374 protein S09 family 0.0095 0.0484 0.1042
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0011 0.000000000023893 0.000000000051474
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0037 0.0037
Brugia malayi PHD-finger family protein 0.0013 0.0009 0.003
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0223 0.1241
Schistosoma mansoni chromobox protein 0.0068 0.0329 0.0709
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0045 0.1069
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0037 0.094
Schistosoma mansoni ap endonuclease 0.0019 0.0045 0.0098
Brugia malayi Carboxylesterase family protein 0.0095 0.0484 0.1521
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.01 0.0515 0.0515
Echinococcus granulosus neuropeptide receptor A26 0.0473 0.2675 0.5763
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.0151 0.0151
Echinococcus granulosus peptidase Clp S14 family 0.0052 0.0235 0.0507
Schistosoma mansoni hypothetical protein 0.0011 0.000000000023893 0.000000000051474
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0084 0.0424 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0045 0.1154
Brugia malayi beta-lactamase 0.004 0.0166 0.0523
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0037 0.0288
Onchocerca volvulus 0.0041 0.0172 0.1348
Echinococcus multilocularis inositol monophosphatase 1 0.0084 0.0424 0.0424
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0037 0.008
Echinococcus granulosus zinc finger protein 0.0021 0.0055 0.0119
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0223 0.1749
Schistosoma mansoni zinc finger protein 0.0021 0.0055 0.0119
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0146 0.0782 0.4502
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0046 0.0204 0.0439
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0015 0.002 0.0043
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0037 0.0289
Mycobacterium leprae conserved hypothetical protein 0.004 0.0166 0.1251
Trypanosoma cruzi trypanothione reductase, putative 0.005 0.0228 0.1268
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0128 0.0677 0.4666
Plasmodium vivax hypothetical protein, conserved 0.004 0.0166 0.423
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0308 0.1737
Echinococcus granulosus GPCR family 2 0.01 0.0515 0.111
Brugia malayi Calcitonin receptor-like protein seb-1 0.0316 0.1768 0.556
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0095 0.0484 0.0484
Loa Loa (eye worm) hypothetical protein 0.0316 0.1768 0.556
Echinococcus granulosus neuroligin 0.0095 0.0484 0.1042
Onchocerca volvulus 0.0095 0.0484 0.3789
Echinococcus granulosus geminin 0.0357 0.2005 0.4319
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0187 0.103
Onchocerca volvulus 0.004 0.0166 0.1302
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0223 0.1241
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0084 0.0424 0.2412
Echinococcus multilocularis polycomb protein SCMH1 0.0094 0.0483 0.0483
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0393 0.4232
Schistosoma mansoni neuroligin 3 (S09 family) 0.0095 0.0484 0.1042
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0156 0.1223
Loa Loa (eye worm) inositol-1 0.0084 0.0424 0.1334
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.0753 0.1623
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0072 0.0155
Schistosoma mansoni ap endonuclease 0.0019 0.0045 0.0098
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0376 0.2116 0.4558
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.0393 0.4232
Schistosoma mansoni cpg binding protein 0.0031 0.0118 0.0254
Schistosoma mansoni hypothetical protein 0.0028 0.01 0.0216
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0064 0.0308 0.0664
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0079 0.0393 0.5134
Onchocerca volvulus 0.0095 0.0484 0.3789
Schistosoma mansoni aldehyde dehydrogenase 0.0064 0.0306 0.066
Mycobacterium ulcerans lipase LipD 0.004 0.0166 0.1537
Echinococcus multilocularis peregrin 0.0031 0.0114 0.0114
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.004 0.0166 0.1537
Brugia malayi PHD-finger family protein 0.0026 0.0086 0.0269
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0223 0.0481
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0045 0.0236
Mycobacterium tuberculosis Conserved protein 0.004 0.0166 0.0942
Loa Loa (eye worm) hypothetical protein 0.01 0.0515 0.1621
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0108 0.0559 0.0559
Giardia lamblia Kinase, CMGC MAPK 0.005 0.0223 1
Echinococcus multilocularis neuroligin 0.0095 0.0484 0.0484
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0037 0.0288
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0095 0.0484 0.3257
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0084 0.0424 0.2412
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0084 0.0424 0.3321
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0045 0.0355
Toxoplasma gondii exonuclease III APE 0.0019 0.0045 0.1069
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0223 0.0702
Brugia malayi beta-NAC-like protein 0.0036 0.0144 0.0454
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0032 0.0069
Echinococcus granulosus SAM and MBT domain containing protein 0.0094 0.0483 0.1041
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0316 0.1768 0.556
Echinococcus granulosus transcription factor Dp 1 0.0037 0.0151 0.0326
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0309 0.1725 1
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0052 0.0235 0.2436
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0095 0.0484 0.1042
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0037 0.094
Echinococcus multilocularis peptidase Clp (S14 family) 0.0052 0.0235 0.0235
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0093 0.2371
Echinococcus multilocularis GPCR, family 2 0.01 0.0515 0.0515
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0037 0.0288
Echinococcus granulosus beta LACTamase domain containing family member 0.004 0.0166 0.0358
Loa Loa (eye worm) hypothetical protein 0.0028 0.01 0.0315
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0037 0.0154
Entamoeba histolytica transcription factor BTF3, putative 0.0036 0.0144 0.3402
Schistosoma mansoni zinc finger protein 0.0015 0.0022 0.0047
Schistosoma mansoni hypothetical protein 0.0578 0.3287 0.7081
Schistosoma mansoni tar DNA-binding protein 0.0202 0.1108 0.2386
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0045 0.0098
Brugia malayi glutathione reductase 0.005 0.0228 0.0717
Schistosoma mansoni hypothetical protein 0.0357 0.2005 0.4319
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0138 0.0298
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.002 0.0154
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.004 0.0166 0.0358
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.005 0.0228 0.1393
Brugia malayi mbt repeat family protein 0.0094 0.0483 0.152
Trypanosoma cruzi ISWI complex protein 0.0015 0.0022 0.0066
Loa Loa (eye worm) CHromoDomain protein family member 0.0015 0.002 0.0063
Mycobacterium tuberculosis Conserved protein 0.004 0.0166 0.0942
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.004 0.0166 0.0523
Schistosoma mansoni tar DNA-binding protein 0.0202 0.1108 0.2386
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0037 0.0154
Echinococcus granulosus peregrin 0.0031 0.0114 0.0245
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0242 0.1351
Echinococcus granulosus acetylcholinesterase 0.0559 0.3179 0.6849
Giardia lamblia PHD finger protein 15 0.0028 0.01 0.3396
Echinococcus granulosus tar DNA binding protein 0.0202 0.1108 0.2386
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0017 0.0133
Loa Loa (eye worm) ICD-1 protein 0.0036 0.0144 0.0454
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0037 0.0154
Echinococcus multilocularis neuropeptide receptor A26 0.0473 0.2675 0.2675
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0037 0.0154
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0037 0.0154
Echinococcus multilocularis tar DNA binding protein 0.0202 0.1108 0.1108
Echinococcus multilocularis Chromo domain 0.0011 0.000000000023893 0.000000000023893
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0037 0.0154
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.004 0.0166 0.0942
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0084 0.0424 0.2412
Trypanosoma cruzi transcription factor btf3, putative 0.0036 0.0144 0.078
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.006 0.0282 0.0282
Mycobacterium ulcerans carboxylesterase, LipT 0.0095 0.0484 0.5311
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0037 0.0288
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0013 0.0009 0.0019
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0093 0.0475 0.1023
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0138 0.0138

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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