Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | FAD linked sulfhydryl oxidase ALR | 0.0036 | 0.1331 | 0.1206 |
Schistosoma mansoni | lamin | 0.0026 | 0.0754 | 0.0621 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0754 | 0.2361 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.3193 | 0.3096 |
Echinococcus multilocularis | musashi | 0.0026 | 0.0754 | 0.0621 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.2328 | 0.7289 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0036 | 0.1331 | 0.5 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.0754 | 0.0621 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.3193 | 0.3096 |
Echinococcus granulosus | tar DNA binding protein | 0.0066 | 0.3193 | 0.3096 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.3193 | 0.3096 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.3193 | 0.3096 |
Brugia malayi | TAR-binding protein | 0.0066 | 0.3193 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.2064 | 0.195 |
Loa Loa (eye worm) | hepatopoietin HPO2 | 0.0036 | 0.1331 | 0.4166 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.2328 | 0.7289 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.0142 | 0.0444 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.2064 | 0.195 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.2328 | 0.7289 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.0142 | 0.0444 |
Brugia malayi | Augmenter of liver regeneration | 0.0036 | 0.1331 | 0.4166 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0048 | 0.2064 | 0.195 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.0754 | 0.0621 |
Toxoplasma gondii | Erv1 / Alr family protein | 0.0036 | 0.1331 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0177 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.2064 | 0.195 |
Brugia malayi | RNA binding protein | 0.0066 | 0.3193 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0066 | 0.3193 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0066 | 0.3193 | 0.3096 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.1316 | 0.4121 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.0754 | 0.2361 |
Echinococcus multilocularis | FAD linked sulfhydryl oxidase ALR | 0.0036 | 0.1331 | 0.1206 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.1316 | 0.1191 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0048 | 0.2064 | 0.195 |
Echinococcus multilocularis | geminin | 0.0177 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0066 | 0.3193 | 0.3096 |
Trypanosoma cruzi | Present in the outer mitochondrial membrane proteome 4 | 0.0036 | 0.1331 | 0.5 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.0754 | 0.2361 |
Loa Loa (eye worm) | TAR-binding protein | 0.0066 | 0.3193 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.0142 | 0.0444 |
Onchocerca volvulus | 0.0026 | 0.0754 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0724 | 0.2268 |
Trypanosoma brucei | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0036 | 0.1331 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0177 | 1 | 1 |
Schistosoma mansoni | lamin | 0.0026 | 0.0754 | 0.0621 |
Trypanosoma cruzi | ERV/ALR sulfhydryl oxidase domain-containing protein | 0.0036 | 0.1331 | 0.5 |
Loa Loa (eye worm) | RNA binding protein | 0.0066 | 0.3193 | 1 |
Toxoplasma gondii | Erv1 / Alr family protein | 0.0036 | 0.1331 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.1316 | 0.4121 |
Echinococcus multilocularis | lamin | 0.0026 | 0.0754 | 0.0621 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.1331 | 0.5 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0754 | 0.2361 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.2064 | 0.195 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0048 | 0.2064 | 0.6464 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0754 | 0.2361 |
Plasmodium falciparum | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0036 | 0.1331 | 0.5 |
Echinococcus granulosus | lamin | 0.0026 | 0.0754 | 0.0621 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.2328 | 0.7289 |
Onchocerca volvulus | 0.0026 | 0.0754 | 0.5 | |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.0754 | 0.0621 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0048 | 0.2064 | 0.6464 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.0754 | 0.0621 |
Plasmodium vivax | FAD-linked sulfhydryl oxidase ERV1, putative | 0.0036 | 0.1331 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0048 | 0.2064 | 0.195 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0066 | 0.3193 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0142 | 0.0444 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.