Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0016 | 0.0207 | 0.0424 | |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0403 | 0.0987 |
Leishmania major | cathepsin L-like protease | 0.0016 | 0.0207 | 0.1713 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0007 | 0.0019 | 0.0546 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.0346 | 1 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0188 | 0.0169 |
Echinococcus granulosus | lamin | 0.0026 | 0.0403 | 0.0385 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0017 | 0.0229 | 0.6617 |
Leishmania major | cathepsin L-like protease | 0.0016 | 0.0207 | 0.1713 |
Echinococcus multilocularis | geminin | 0.0511 | 1 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0346 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0471 | 0.0453 |
Echinococcus multilocularis | cysteine protease | 0.0016 | 0.0207 | 0.0189 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.112 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0229 | 0.054 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0346 | 0.0841 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.112 | 1 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0015 | 0.0188 | 0.1534 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0513 | 0.0495 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0207 | 0.0484 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0513 | 0.0495 |
Schistosoma mansoni | lamin | 0.0026 | 0.0403 | 0.0385 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0008 | 0.005 | 0.0112 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0016 | 0.0207 | 0.0681 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0013 | 0.0134 | 0.0115 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0061 | 0.1085 | 0.1068 |
Plasmodium vivax | unspecified product | 0.0008 | 0.005 | 0.0688 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0093 | 0.1727 | 0.1711 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0008 | 0.005 | 0.0031 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.0346 | 0.1184 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0438 | 0.042 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0016 | 0.0207 | 0.0681 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0007 | 0.0019 | 0.0546 |
Plasmodium vivax | vivapain-3 | 0.0008 | 0.005 | 0.0688 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0016 | 0.0207 | 0.8964 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.0346 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0207 | 0.0445 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0207 | 0.0445 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0008 | 0.005 | 0.0112 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0016 | 0.0207 | 0.0189 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0016 | 0.0207 | 0.0189 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0016 | 0.0207 | 0.0484 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0016 | 0.0207 | 0.8964 |
Entamoeba histolytica | cysteine protease, putative | 0.0008 | 0.005 | 0.0112 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0101 | 0.1874 | 0.4765 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.021 | 0.6071 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0008 | 0.005 | 0.008 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.01 | 0.0208 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.112 | 1 |
Onchocerca volvulus | 0.0016 | 0.0207 | 0.0424 | |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.1244 | 0.3147 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0229 | 0.054 |
Trypanosoma cruzi | isocitrate dehydrogenase, putative | 0.0015 | 0.0188 | 0.1534 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0015 | 0.0188 | 0.0434 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0207 | 0.0484 |
Trypanosoma cruzi | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0015 | 0.0188 | 0.1534 |
Entamoeba histolytica | cysteine protease, putative | 0.0008 | 0.005 | 0.0112 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0016 | 0.0207 | 0.0189 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0147 | 0.2786 | 0.2772 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0513 | 0.1269 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0229 | 0.054 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0346 | 0.0841 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0207 | 0.0445 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0346 | 0.0841 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.044 | 0.108 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.112 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0032 | 0.0513 | 0.1269 |
Schistosoma mansoni | lamin | 0.0026 | 0.0403 | 0.0385 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0207 | 0.0484 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0093 | 0.1727 | 0.1711 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0188 | 0.0169 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.0403 | 0.0385 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.112 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0042 | 0.0023 |
Leishmania major | cathepsin L-like protease | 0.0016 | 0.0207 | 0.1713 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.1727 | 0.1711 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.0019 | 0.0546 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.0346 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0011 | 0.01 | 0.0208 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0008 | 0.005 | 0.0112 |
Echinococcus multilocularis | cysteine protease | 0.0016 | 0.0207 | 0.0189 |
Plasmodium vivax | isocitrate dehydrogenase [NADP], mitochondrial, putative | 0.0015 | 0.0188 | 0.3734 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0032 | 0.0513 | 0.1269 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.0403 | 0.0987 |
Echinococcus multilocularis | lamin | 0.0026 | 0.0403 | 0.0385 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.0019 | 0.0546 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0207 | 0.0445 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0008 | 0.005 | 0.0283 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0016 | 0.0207 | 0.0189 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0207 | 0.0445 |
Toxoplasma gondii | cathepsin CPL | 0.0016 | 0.0207 | 0.2005 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0016 | 0.0207 | 0.0189 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0207 | 0.0445 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0007 | 0.0019 | 0.0546 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0007 | 0.0019 | 0.0546 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0207 | 0.0484 |
Leishmania major | cysteine peptidase A (CPA) | 0.0016 | 0.0207 | 0.1713 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0008 | 0.005 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.01 | 0.0208 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0207 | 0.0445 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.0346 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0008 | 0.005 | 0.0112 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0346 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0101 | 0.1874 | 0.4765 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0076 | 0.0057 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0513 | 0.0495 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0346 | 0.1184 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0229 | 0.054 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0011 | 0.01 | 0.0293 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0207 | 0.0445 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0076 | 0.0147 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0471 | 0.1162 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0188 | 0.0169 |
Echinococcus granulosus | cathepsin L | 0.0008 | 0.005 | 0.0031 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0513 | 0.0495 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0007 | 0.0019 | 0.0022 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0125 | 0.0271 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0016 | 0.0207 | 0.1713 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0207 | 0.0445 |
Loa Loa (eye worm) | ctsf protein | 0.0016 | 0.0207 | 0.0484 |
Echinococcus multilocularis | dnaJ subfamily B | 0.04 | 0.7813 | 0.7808 |
Echinococcus granulosus | dnaJ subfamily B | 0.04 | 0.7813 | 0.7808 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0015 | 0.0188 | 0.1534 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0008 | 0.005 | 0.0283 |
Echinococcus multilocularis | musashi | 0.0026 | 0.0403 | 0.0385 |
Brugia malayi | Cathepsin L-like precursor | 0.0011 | 0.01 | 0.0208 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0207 | 0.0484 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.0346 | 1 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.0403 | 0.0987 |
Plasmodium falciparum | isocitrate dehydrogenase [NADP], mitochondrial | 0.0015 | 0.0188 | 0.8031 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0011 | 0.01 | 0.0208 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.112 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0207 | 0.0445 |
Onchocerca volvulus | Cathepsin L homolog | 0.0016 | 0.0207 | 0.0424 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0017 | 0.0229 | 0.4649 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.044 | 0.0421 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0346 | 0.2975 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0015 | 0.0188 | 0.1797 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0207 | 0.0445 |
Onchocerca volvulus | 0.0016 | 0.0207 | 0.0424 | |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0015 | 0.0188 | 0.0169 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0207 | 0.0445 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0093 | 0.1727 | 0.4386 |
Schistosoma mansoni | hypothetical protein | 0.0147 | 0.2786 | 0.2772 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0049 | 0.0855 | 0.7595 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0471 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0016 | 0.0207 | 0.0484 |
Onchocerca volvulus | 0.0016 | 0.0207 | 0.0424 | |
Echinococcus multilocularis | GPCR, family 2 | 0.0032 | 0.0513 | 0.0495 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0207 | 0.0445 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0069 | 0.1244 | 0.3147 |
Echinococcus granulosus | GPCR family 2 | 0.0032 | 0.0513 | 0.0495 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.021 | 0.6071 |
Brugia malayi | Isocitrate dehydrogenase | 0.0015 | 0.0188 | 0.0434 |
Toxoplasma gondii | isocitrate dehydrogenase | 0.0015 | 0.0188 | 0.1797 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0346 | 0.2975 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.0346 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0011 | 0.01 | 0.0204 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0057 | 0.1012 | 0.9025 |
Entamoeba histolytica | cysteine protease, putative | 0.0008 | 0.005 | 0.0112 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.112 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0008 | 0.005 | 0.0112 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0207 | 0.0445 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.112 | 1 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.0019 | 0.0546 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0008 | 0.005 | 0.0283 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0394 | 0.0963 |
Onchocerca volvulus | 0.0026 | 0.0403 | 0.0864 | |
Plasmodium vivax | vivapain-1 | 0.0008 | 0.005 | 0.0688 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0008 | 0.005 | 0.0112 |
Onchocerca volvulus | 0.0028 | 0.044 | 0.0946 | |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.0403 | 0.0385 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0346 | 0.0841 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0008 | 0.0042 | 0.0023 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0207 | 0.0445 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0471 | 0.0453 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.001 | 0.0074 | 0.0142 |
Brugia malayi | hypothetical protein | 0.0147 | 0.2786 | 0.7105 |
Entamoeba histolytica | cysteine protease, putative | 0.0008 | 0.005 | 0.0112 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.0125 | 0.0271 |
Entamoeba histolytica | hypothetical protein | 0.0147 | 0.2786 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0207 | 0.0445 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0076 | 0.0057 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0471 | 0.0453 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.0162 | 0.0367 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0017 | 0.0229 | 0.5 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0008 | 0.005 | 0.0112 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.112 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0016 | 0.0207 | 0.8964 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0229 | 0.054 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.021 | 0.6071 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0008 | 0.005 | 0.1479 |
Onchocerca volvulus | 0.0026 | 0.0403 | 0.0864 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0207 | 0.0445 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0014 | 0.0162 | 0.0367 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.0346 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.0232 | 0.4468 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0008 | 0.005 | 0.0112 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0054 | 0.0959 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0207 | 0.0445 |
Entamoeba histolytica | cysteine protease, putative | 0.0008 | 0.005 | 0.0112 |
Entamoeba histolytica | cysteine protease, putative | 0.0008 | 0.005 | 0.0112 |
Plasmodium vivax | vivapain-2 | 0.0016 | 0.0207 | 0.4167 |
Entamoeba histolytica | cysteine protease, putative | 0.0008 | 0.005 | 0.0112 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0016 | 0.0207 | 0.0189 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0207 | 0.0445 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.112 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0016 | 0.0207 | 0.0445 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0346 | 0.0841 |
Trypanosoma cruzi | cysteine protease, putative | 0.0008 | 0.005 | 0.0283 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0008 | 0.005 | 0.0031 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0016 | 0.0207 | 0.0484 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0008 | 0.005 | 0.008 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0007 | 0.0019 | 0.0546 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0093 | 0.1727 | 0.1711 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0017 | 0.0229 | 0.6421 |
Echinococcus granulosus | cathepsin l1 | 0.0011 | 0.01 | 0.0081 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0008 | 0.005 | 0.0092 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0017 | 0.021 | 0.6071 |
Onchocerca volvulus | 0.0016 | 0.0207 | 0.0424 | |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.1244 | 0.1228 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0007 | 0.0019 | 0.0546 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.0346 | 1 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.0403 | 0.0385 |
Entamoeba histolytica | cysteine protease, putative | 0.0008 | 0.005 | 0.0112 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.112 | 1 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.003 | 0.0471 | 0.0453 |
Echinococcus multilocularis | cathepsin L | 0.0008 | 0.005 | 0.0031 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0016 | 0.0207 | 0.0484 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0008 | 0.005 | 0.0283 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0471 | 0.4812 |
Loa Loa (eye worm) | cysteine protease | 0.0016 | 0.0207 | 0.0484 |
Onchocerca volvulus | 0.0016 | 0.0207 | 0.0424 | |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0007 | 0.0019 | 0.0546 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.112 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0016 | 0.0207 | 0.0189 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.0346 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0207 | 0.0445 |
Schistosoma mansoni | hypothetical protein | 0.0511 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0008 | 0.005 | 0.0112 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0032 | 0.0513 | 0.1269 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0471 | 0.0453 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0403 | 0.0987 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0471 | 0.0453 |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0207 | 0.0484 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0207 | 0.0445 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0403 | 0.0987 |
Brugia malayi | Cathepsin L-like precursor | 0.0011 | 0.01 | 0.0208 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0513 | 0.0495 |
Leishmania major | cathepsin L-like protease | 0.0016 | 0.0207 | 0.1713 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0016 | 0.0207 | 0.0445 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0017 | 0.0229 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.1727 | 0.1711 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0093 | 0.1727 | 0.4386 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0134 | 0.0296 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0007 | 0.0019 | 0.0546 |
Entamoeba histolytica | cysteine protease, putative | 0.0008 | 0.005 | 0.0112 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.112 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.1874 | 0.4765 |
Brugia malayi | isocitrate dehydrogenase | 0.0015 | 0.0188 | 0.0434 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0011 | 0.01 | 0.0204 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.0471 | 0.0453 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.0403 | 0.0385 |
Onchocerca volvulus | 0.0016 | 0.0207 | 0.0424 | |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0008 | 0.0042 | 0.0023 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0016 | 0.0207 | 0.0445 |
Onchocerca volvulus | 0.0011 | 0.01 | 0.0182 | |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0147 | 0.2786 | 0.2772 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.01 | 0.0208 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.044 | 0.108 |
Onchocerca volvulus | 0.003 | 0.0471 | 0.1017 | |
Brugia malayi | Pre-SET motif family protein | 0.0203 | 0.3913 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0011 | 0.01 | 0.0081 |
Onchocerca volvulus | 0.0232 | 0.4468 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0016 | 0.0207 | 0.0484 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0016 | 0.0207 | 0.0189 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.0346 | 0.1184 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0471 | 0.0453 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0015 | 0.0188 | 0.0169 |
Onchocerca volvulus | Cathepsin F homolog | 0.0016 | 0.0207 | 0.0424 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0346 | 0.0841 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0101 | 0.1874 | 0.4765 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0008 | 0.0042 | 0.0023 |
Plasmodium vivax | vivapain-2 | 0.0016 | 0.0207 | 0.4167 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0008 | 0.005 | 0.0283 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0008 | 0.005 | 0.0092 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0016 | 0.0207 | 0.0445 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.112 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0016 | 0.0207 | 0.0424 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.0471 | 0.0453 |
Entamoeba histolytica | hypothetical protein | 0.0147 | 0.2786 | 1 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0013 | 0.0134 | 0.0115 |
Leishmania major | cathepsin L-like protease | 0.0016 | 0.0207 | 0.1713 |
Echinococcus granulosus | cathepsin l1 | 0.0016 | 0.0207 | 0.0189 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0008 | 0.005 | 0.0283 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0513 | 0.0495 |
Entamoeba histolytica | cysteine protease, putative | 0.0016 | 0.0207 | 0.0681 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0008 | 0.0042 | 0.0023 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0008 | 0.005 | 0.0031 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0062 | 0.112 | 1 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0007 | 0.0019 | 0.0022 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0015 | 0.0188 | 0.0169 |
Onchocerca volvulus | 0.0023 | 0.0346 | 0.0736 | |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0093 | 0.1727 | 0.1711 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.003 | 0.0471 | 0.0453 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0513 | 0.0495 |
Leishmania major | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0015 | 0.0188 | 0.1534 |
Leishmania major | cathepsin L-like protease | 0.0062 | 0.112 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0511 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0093 | 0.1727 | 0.1711 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0471 | 0.1162 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0203 | 0.3913 | 1 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0471 | 0.0453 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0015 | 0.0188 | 0.0169 |
Entamoeba histolytica | hypothetical protein | 0.0147 | 0.2786 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0032 | 0.0513 | 0.0495 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.0346 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0147 | 0.2786 | 0.2772 |
Entamoeba histolytica | cysteine protease, putative | 0.0008 | 0.005 | 0.0112 |
Entamoeba histolytica | hypothetical protein | 0.0147 | 0.2786 | 1 |
Echinococcus granulosus | cysteine protease | 0.0008 | 0.005 | 0.0031 |
Mycobacterium tuberculosis | Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) | 0.0015 | 0.0188 | 0.5422 |
Schistosoma mansoni | hypothetical protein | 0.04 | 0.7813 | 0.7808 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.112 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.0346 | 0.2975 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.112 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.