Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.0198 | 0.7224 | 0.7224 |
Loa Loa (eye worm) | proteasome subunit beta type 2 | 0.0123 | 0.3546 | 0.3546 |
Trypanosoma brucei | proteasome subunit beta type-5, putative | 0.0255 | 1 | 1 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.0198 | 0.7224 | 0.7224 |
Toxoplasma gondii | proteasome subunit beta type 1, putative | 0.0198 | 0.7224 | 0.7224 |
Entamoeba histolytica | proteasome subunit beta type 5 precursor, putative | 0.0255 | 1 | 1 |
Leishmania major | proteasome beta 2 subunit, putative | 0.0123 | 0.3546 | 0.3546 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0123 | 0.3546 | 0.3546 |
Loa Loa (eye worm) | proteasome subunit beta type 1 | 0.0198 | 0.7224 | 0.7224 |
Plasmodium falciparum | proteasome subunit beta type-1, putative | 0.0198 | 0.7224 | 0.7224 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0123 | 0.3546 | 0.3546 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0123 | 0.3546 | 0.3546 |
Plasmodium vivax | proteasome subunit beta type-1, putative | 0.0198 | 0.7224 | 0.7224 |
Giardia lamblia | Proteasome subunit beta type 5 precursor | 0.0255 | 1 | 1 |
Echinococcus multilocularis | proteasome (prosome, macropain) | 0.0255 | 1 | 1 |
Brugia malayi | proteasome subunit beta type 2 | 0.0123 | 0.3546 | 0.3546 |
Giardia lamblia | Proteasome subunit beta type 2 | 0.0123 | 0.3546 | 0.3546 |
Schistosoma mansoni | proteasome subunit beta 1 (T01 family) | 0.0198 | 0.7224 | 0.7224 |
Trypanosoma cruzi | 20S proteasome subunit | 0.0123 | 0.3546 | 0.3546 |
Echinococcus granulosus | proteasome prosome macropain subunit beta | 0.0123 | 0.3546 | 0.3546 |
Mycobacterium leprae | proteasome (beta subunit) PrcB | 0.0255 | 1 | 1 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0255 | 1 | 1 |
Schistosoma mansoni | proteasome catalytic subunit 3 (T01 family) | 0.0255 | 1 | 1 |
Mycobacterium ulcerans | proteasome PrcB | 0.0255 | 1 | 1 |
Trypanosoma cruzi | proteasome subunit beta type-2, putative | 0.0123 | 0.3546 | 0.3546 |
Schistosoma mansoni | proteasome subunit beta 2 (T01 family) | 0.0123 | 0.3546 | 0.3546 |
Plasmodium vivax | proteasome subunit beta type-2, putative | 0.0123 | 0.3546 | 0.3546 |
Trypanosoma brucei | proteasome subunit beta type-2, putative | 0.0123 | 0.3546 | 0.3546 |
Loa Loa (eye worm) | proteasome A-type and B-type family protein | 0.0255 | 1 | 1 |
Plasmodium falciparum | proteasome subunit beta type-2, putative | 0.0123 | 0.3546 | 0.3546 |
Trypanosoma brucei | proteasome beta 6 subunit | 0.0198 | 0.7224 | 0.7224 |
Leishmania major | proteasome beta 5 subunit, putative | 0.0255 | 1 | 1 |
Brugia malayi | proteasome subunit beta type 1 | 0.0198 | 0.7224 | 0.7224 |
Echinococcus granulosus | proteasome prosome macropain | 0.0255 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent protease peptidase subunit | 0.005 | 0 | 0.5 |
Echinococcus multilocularis | proteasome (prosome, macropain) subunit, beta | 0.0123 | 0.3546 | 0.3546 |
Leishmania major | proteasome beta 6 subunit, putative,20S proteasome beta 6 subunit, putative | 0.0198 | 0.7224 | 0.7224 |
Toxoplasma gondii | proteasome subunit beta type, putative | 0.0255 | 1 | 1 |
Plasmodium vivax | proteasome subunit beta type-5, putative | 0.0255 | 1 | 1 |
Toxoplasma gondii | proteasome subunit beta type 2, putative | 0.0123 | 0.3546 | 0.3546 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0198 | 0.7224 | 0.7224 |
Trichomonas vaginalis | Family T1, proteasome beta subunit, threonine peptidase | 0.0198 | 0.7224 | 0.7224 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0255 | 1 | 1 |
Plasmodium falciparum | proteasome subunit beta type-5 | 0.0255 | 1 | 1 |
Giardia lamblia | Proteasome subunit beta type 1 | 0.0198 | 0.7224 | 0.7224 |
Entamoeba histolytica | proteasome subunit beta type 1, putative | 0.0198 | 0.7224 | 0.7224 |
Entamoeba histolytica | probable proteasome subunit beta type 2, putative | 0.0123 | 0.3546 | 0.3546 |
Onchocerca volvulus | Notchless protein homolog | 0.005 | 0 | 0.5 |
Mycobacterium tuberculosis | Proteasome beta subunit PrcB; assembles with alpha subunit PrcA. | 0.0255 | 1 | 1 |
Trypanosoma cruzi | proteasome beta 6 subunit, putative | 0.0198 | 0.7224 | 0.7224 |
Trypanosoma cruzi | proteasome subunit beta type-5, putative | 0.0255 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.