Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.0019 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.6198 | 0.5563 |
Echinococcus granulosus | roundabout 2 | 0.0015 | 0.6198 | 0.6198 |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.0019 | 1 | 0.5 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0019 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.1432 | 0.00000000841 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0019 | 1 | 1 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.001 | 0.1432 | 1 |
Schistosoma mansoni | Neurotrimin precursor (hNT) | 0.0015 | 0.6198 | 0.6198 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0019 | 1 | 1 |
Schistosoma mansoni | vesicular amine transporter | 0.0015 | 0.6198 | 0.6198 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.0019 | 1 | 1 |
Treponema pallidum | ATP-dependent DNA helicase | 0.001 | 0.1432 | 1 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0019 | 1 | 1 |
Schistosoma mansoni | DNA helicase recq5 | 0.0019 | 1 | 1 |
Echinococcus granulosus | defective proboscis extension response | 0.0015 | 0.6198 | 0.6198 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.0019 | 1 | 0.5 |
Echinococcus multilocularis | bloom syndrome protein | 0.0019 | 1 | 1 |
Entamoeba histolytica | recQ family DNA helicase | 0.001 | 0.1432 | 0.0381 |
Mycobacterium tuberculosis | Probable bacterioferritin BfrA | 0.0008 | 0 | 0.5 |
Echinococcus multilocularis | Immunoglobulin | 0.0015 | 0.6198 | 0.6198 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.0019 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.6198 | 0.5563 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0019 | 1 | 1 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.0019 | 1 | 1 |
Echinococcus granulosus | bloom syndrome protein | 0.0019 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | bacterioferritin/cytochrome b1 | 0.0008 | 0 | 0.5 |
Schistosoma mansoni | nephrin | 0.0015 | 0.6198 | 0.6198 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0009 | 0.1093 | 0.1093 |
Schistosoma mansoni | cell adhesion molecule | 0.0015 | 0.6198 | 0.6198 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.6198 | 0.5563 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.0019 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.6198 | 0.5563 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.6198 | 0.5563 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0019 | 1 | 0.5 |
Echinococcus multilocularis | roundabout 2 | 0.0015 | 0.6198 | 0.6198 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0019 | 1 | 1 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0019 | 1 | 1 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0016 | 0.7441 | 0.3268 |
Mycobacterium tuberculosis | Bacterioferritin BfrB | 0.0008 | 0 | 0.5 |
Mycobacterium leprae | PROBABLE BACTERIOFERRITIN BFRA | 0.0008 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.6198 | 0.5563 |
Entamoeba histolytica | recQ family helicase, putative | 0.0019 | 1 | 1 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0015 | 0.6198 | 0.6198 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.6198 | 0.5563 |
Loa Loa (eye worm) | RecQ helicase | 0.0019 | 1 | 1 |
Schistosoma mansoni | defective proboscis extension response (dpr)-related | 0.0015 | 0.6198 | 0.6198 |
Schistosoma mansoni | DNA helicase recq1 | 0.0019 | 1 | 1 |
Echinococcus granulosus | neuroglian | 0.0015 | 0.6198 | 0.6198 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0016 | 0.7441 | 0.7013 |
Mycobacterium ulcerans | bacterioferritin BfrA | 0.0008 | 0 | 0.5 |
Echinococcus granulosus | twitchin | 0.0015 | 0.6198 | 0.6198 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0019 | 1 | 0.5 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.1432 | 0.0381 |
Echinococcus multilocularis | neuroglian | 0.0015 | 0.6198 | 0.6198 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.001 | 0.1432 | 0.1432 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0019 | 1 | 0.5 |
Echinococcus granulosus | Immunoglobulin | 0.0015 | 0.6198 | 0.6198 |
Echinococcus multilocularis | basement membrane specific heparan sulfate | 0.0015 | 0.6198 | 0.6198 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.6198 | 0.5563 |
Mycobacterium ulcerans | bacterioferritin BfrB | 0.0008 | 0 | 0.5 |
Echinococcus multilocularis | Immunoglobulin | 0.0015 | 0.6198 | 0.6198 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.6198 | 0.5563 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0019 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.