Detailed information for compound 64542

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 310.473 | Formula: C22H30O
  • H donors: 1 H acceptors: 1 LogP: 6.42 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCC/C=C/1\CCC2C1(C)CCC1C2CCc2c1ccc(c2)O
  • InChi: 1S/C22H30O/c1-3-4-5-16-7-11-21-20-9-6-15-14-17(23)8-10-18(15)19(20)12-13-22(16,21)2/h5,8,10,14,19-21,23H,3-4,6-7,9,11-13H2,1-2H3/b16-5+
  • InChiKey: LIFOFJDYOCSIIT-FZSIALSZSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0053 0.0493 0.0493
Brugia malayi Hypothetical subtilase-type proteinase F21H12.6 in chromosome II 0.0015 0.0015 0.0036
Schistosoma mansoni potassium channel beta 0.0031 0.0217 0.0449
Loa Loa (eye worm) hypothetical protein 0.0045 0.0399 0.0938
Plasmodium falciparum cysteine repeat modular protein 1 0.0113 0.1251 1
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0045 0.0399 0.0826
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0281 0.0581
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0045 0.0399 0.0826
Brugia malayi Trypsin family protein 0.0019 0.0065 0.0152
Brugia malayi Kringle domain containing protein 0.0113 0.1251 0.2937
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0053 0.0493 0.1018
Loa Loa (eye worm) abnormal epIthelia family member 0.0024 0.013 0.0306
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0053 0.0493 0.1157
Schistosoma mansoni hypothetical protein 0.0031 0.0221 0.0457
Loa Loa (eye worm) nuclear receptor NHR-67 0.0021 0.0099 0.0231
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.051 0.4001
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0669 0.24
Loa Loa (eye worm) hypothetical protein 0.0344 0.4165 0.9783
Trichomonas vaginalis set domain proteins, putative 0.0231 0.2738 1
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0669 0.24
Trypanosoma brucei prostaglandin f synthase 0.0053 0.0493 1
Trypanosoma cruzi hypothetical protein, conserved 0.0113 0.1251 1
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.0675 0.1584
Onchocerca volvulus 0.0053 0.0493 0.1799
Trypanosoma cruzi aldo/keto reductase, putative 0.0031 0.0217 0.1634
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0081 0.0854 0.308
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0045 0.0399 0.0399
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0045 0.0399 0.0938
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0053 0.0493 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0045 0.0399 0.0938
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0182 0.0426
Brugia malayi nuclear receptor NHR-67 0.0021 0.0099 0.0231
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0053 0.0493 0.1018
Onchocerca volvulus Arrow homolog 0.0016 0.0029 0.0105
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0045 0.0399 0.1459
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0351 0.4258 0.4258
Echinococcus multilocularis ecdysone induced protein 78C 0.0045 0.0399 0.0399
Echinococcus multilocularis ubiquitin specific protease 41 0.0039 0.0319 0.0319
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0028 0.0028
Echinococcus granulosus geminin 0.0165 0.1905 0.3937
Mycobacterium leprae Possible oxidoreductase 0.0031 0.0217 0.4228
Loa Loa (eye worm) hypothetical protein 0.0019 0.0065 0.0152
Loa Loa (eye worm) hypothetical protein 0.0021 0.0099 0.0231
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0053 0.0493 0.1753
Brugia malayi steroid hormone receptor 0.0045 0.0399 0.0938
Echinococcus granulosus membrane bound transcription factor site 1 0.0015 0.0015 0.0031
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0039 0.0319 0.066
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0045 0.0399 0.0938
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0065 0.0134
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0045 0.0399 0.0826
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0347 0.0815
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0053 0.0493 0.1018
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0319 0.2461
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.0209 0.2465 0.5095
Brugia malayi Trypsin family protein 0.0019 0.0065 0.0152
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0053 0.0493 0.0493
Loa Loa (eye worm) hypothetical protein 0.0024 0.0131 0.0307
Echinococcus multilocularis FTZ F1 alpha 0.0045 0.0399 0.0399
Echinococcus granulosus neurogenic locus notch protein 0.0024 0.013 0.0269
Brugia malayi NADH-dependent xylose reductase 0.0031 0.0217 0.051
Echinococcus granulosus chaperonin containing TCP1 subunit 2 beta 0.0023 0.0125 0.0258
Echinococcus multilocularis dnaJ subfamily B 0.0397 0.4838 0.4838
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0028 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0669 0.24
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0019 0.0065 0.0065
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0021 0.0099 0.036
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0045 0.0399 0.0826
Schistosoma mansoni cpg binding protein 0.0028 0.0182 0.0375
Toxoplasma gondii kringle domain-containing protein 0.0113 0.1251 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0028 0.0028
Brugia malayi hypothetical protein 0.0024 0.0131 0.0307
Brugia malayi Thrombospondin N-terminal -like domain containing protein 0.0024 0.013 0.0306
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0081 0.0854 0.308
Trichomonas vaginalis chaperonin, putative 0.0023 0.0125 0.0403
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0065 0.0134
Entamoeba histolytica aldose reductase, putative 0.0053 0.0493 0.4039
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0669 0.24
Trichomonas vaginalis aldo/keto reductase, putative 0.0053 0.0493 0.1753
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0669 0.24
Loa Loa (eye worm) hypothetical protein 0.0021 0.0099 0.0231
Schistosoma mansoni furin-1 (S08 family) 0.015 0.1716 0.3547
Onchocerca volvulus 0.0113 0.1251 0.4568
Brugia malayi Fibulin-1 precursor 0.0016 0.0029 0.0067
Echinococcus granulosus voltage gated potassium channel subunit 0.0031 0.0217 0.0449
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0019 0.0065 0.0152
Schistosoma mansoni nuclear hormone receptor 0.0045 0.0399 0.0826
Brugia malayi hypothetical protein 0.0019 0.0065 0.0152
Echinococcus granulosus peptidase s8 s53 subtilisin kexin sedolisin 0.0015 0.0015 0.0031
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0024 0.0131 0.0131
Brugia malayi Nuclear hormone receptor-like 1 0.0024 0.0131 0.0307
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0039 0.0319 0.2461
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0319 0.1117
Echinococcus multilocularis neurogenic locus notch protein 0.0024 0.013 0.013
Schistosoma mansoni cpg binding protein 0.0029 0.0202 0.0417
Schistosoma mansoni laminin gamma-3 chain 0.003 0.0206 0.0426
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0028 0.0104
Toxoplasma gondii calcium binding egf domain-containing protein 0.0016 0.0029 0.0109
Schistosoma mansoni egf-like domain protein 0.0016 0.0029 0.0059
Loa Loa (eye worm) hypothetical protein 0.0019 0.0065 0.0152
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0028 0.0028
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0045 0.0399 0.0399
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0016 0.0029 0.0067
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0028 0.0269
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0281 0.0581
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0045 0.0399 0.0826
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0028 0.0104
Echinococcus granulosus hypothetical protein 0.0053 0.0493 0.1018
Schistosoma mansoni pol-related 0.0053 0.0493 0.1018
Schistosoma mansoni slit 0.003 0.0206 0.0426
Brugia malayi Nuclear hormone receptor-like 1 0.0024 0.0131 0.0307
Entamoeba histolytica hypothetical protein 0.0036 0.0281 0.1717
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0031 0.0221 0.0221
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0319 0.066
Onchocerca volvulus 0.0019 0.0065 0.0236
Brugia malayi proprotein convertase 2 0.0216 0.2554 0.5999
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0053 0.0493 0.1018
Loa Loa (eye worm) TK/ROR protein kinase 0.0113 0.1251 0.2937
Echinococcus multilocularis protein patched 0.0041 0.0347 0.0347
Brugia malayi celfurPC protein 0.0277 0.3327 0.7813
Brugia malayi conserved hypotetical protein 0.0021 0.0099 0.0231
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0065 0.0134
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0021 0.0099 0.0099
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0045 0.0399 0.0399
Schistosoma mansoni thyroid hormone receptor 0.0045 0.0399 0.0826
Echinococcus multilocularis cpg binding protein 0.0029 0.0202 0.0202
Echinococcus granulosus ecdysone induced protein 78C 0.0045 0.0399 0.0826
Echinococcus multilocularis 0.0277 0.3327 0.3327
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0021 0.0099 0.036
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0217 0.0741
Brugia malayi isocitrate dehydrogenase 0.0016 0.0028 0.0066
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0039 0.0319 0.075
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0347 0.0718
Loa Loa (eye worm) hypothetical protein 0.0098 0.1065 0.2502
Loa Loa (eye worm) hypothetical protein 0.0024 0.0131 0.0307
Schistosoma mansoni hypothetical protein 0.0397 0.4838 1
Loa Loa (eye worm) hypothetical protein 0.0067 0.0675 0.1584
Loa Loa (eye worm) hypothetical protein 0.0021 0.0099 0.0231
Onchocerca volvulus 0.0019 0.0065 0.0236
Leishmania major aldo/keto reductase, putative,aldo/keto reductase family-like protein 0.0031 0.0217 0.1634
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0045 0.0399 0.0826
Brugia malayi Trypsin family protein 0.0019 0.0065 0.0152
Trypanosoma cruzi aldo-keto reductase 0.0053 0.0493 0.3864
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0045 0.0399 0.0399
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0021 0.0099 0.0231
Loa Loa (eye worm) hypothetical protein 0.0021 0.0099 0.0231
Giardia lamblia Furin precursor putative serine protease 0.0066 0.0669 0.4131
Brugia malayi laminin-like protein K08C7.3 precursor 0.0024 0.013 0.0306
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0053 0.0493 0.1157
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0045 0.0399 0.0938
Loa Loa (eye worm) hypothetical protein 0.0041 0.0347 0.0815
Echinococcus multilocularis geminin 0.0165 0.1905 0.1905
Loa Loa (eye worm) subtilase 0.0015 0.0015 0.0036
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0098 0.1065 0.2502
Loa Loa (eye worm) hypothetical protein 0.0024 0.0131 0.0307
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0065 0.0134
Echinococcus granulosus thyroid hormone receptor alpha 0.0021 0.0099 0.0204
Schistosoma mansoni site-1 peptidase (S08 family) 0.0015 0.0015 0.0031
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0081 0.0854 0.308
Brugia malayi Pre-SET motif family protein 0.0203 0.2386 0.5603
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0281 0.0281
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0039 0.0319 0.066
Brugia malayi Calcium binding EGF domain containing protein 0.0016 0.0029 0.0067
Onchocerca volvulus 0.0053 0.0493 0.1799
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0019 0.0065 0.0134
Echinococcus multilocularis chaperonin containing TCP1, subunit 2 (beta) 0.0023 0.0125 0.0125
Echinococcus granulosus enteropeptidase 0.0019 0.0065 0.0134
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0045 0.0399 0.0938
Echinococcus granulosus glycoprotein Antigen 5 0.0019 0.0065 0.0134
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0028 0.0104
Onchocerca volvulus 0.0231 0.2738 1
Schistosoma mansoni cpg binding protein 0.0029 0.0202 0.0417
Brugia malayi EGF-like domain containing protein 0.003 0.0206 0.0484
Brugia malayi nuclear hormone receptor family member nhr-6 0.0021 0.0099 0.0231
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.0067
Loa Loa (eye worm) glutamate-cysteine ligase modifier subunit 0.0031 0.0217 0.051
Echinococcus multilocularis pikachurin 0.0024 0.013 0.013
Echinococcus granulosus transmembrane protease serine 3 0.0019 0.0065 0.0134
Echinococcus granulosus cpg binding protein 0.0029 0.0202 0.0417
Echinococcus granulosus Niemann Pick C1 protein 0.0096 0.1035 0.214
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0053 0.0493 0.1018
Schistosoma mansoni hypothetical protein 0.0031 0.0221 0.0457
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0081 0.0854 0.308
Brugia malayi tailless protein 0.0021 0.0099 0.0231
Entamoeba histolytica hypothetical protein 0.0036 0.0281 0.1717
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0053 0.0493 0.1018
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.0209 0.2465 0.2465
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0209 0.2465 0.8998
Leishmania major aldo-keto reductase-like protein 0.0053 0.0493 0.3864
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0021 0.0099 0.0204
Echinococcus granulosus Niemann Pick C1 protein 0.0137 0.1553 0.3209
Echinococcus multilocularis Mastin 0.0019 0.0065 0.0065
Loa Loa (eye worm) DR-78 0.0021 0.0099 0.0231
Brugia malayi Niemann-Pick C1 protein precursor 0.0096 0.1035 0.2431
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0182 0.0376
Entamoeba histolytica alcohol dehydrogenase, putative 0.0031 0.0217 0.1013
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0053 0.0493 0.0493
Loa Loa (eye worm) hypothetical protein 0.0021 0.0099 0.0231
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0053 0.0493 0.1753
Brugia malayi Membrane-bound transcription factor site-1 protease precursor 0.0015 0.0015 0.0036
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0351 0.4258 1
Schistosoma mansoni zinc finger protein 0.0021 0.0099 0.0204
Brugia malayi Steroid receptor seven-up type 2 0.0045 0.0399 0.0938
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0351 0.4258 0.8802
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0065 0.0134
Toxoplasma gondii aldo/keto reductase family oxidoreductase 0.0031 0.0217 0.1634
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0065 0.0134
Trypanosoma brucei aldo-keto reductase, putative 0.0053 0.0493 1
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0028 0.0058
Trichomonas vaginalis aldo-keto reductase, putative 0.0053 0.0493 0.1753
Echinococcus multilocularis transmembrane protease serine 3 0.0019 0.0065 0.0065
Schistosoma mansoni chondroitin sulfate proteoglycan-related 0.0024 0.013 0.0269
Loa Loa (eye worm) hypothetical protein 0.0024 0.0131 0.0307
Echinococcus multilocularis nuclear receptor nhr 48 0.0021 0.0099 0.0099
Trichomonas vaginalis aldo/keto reductase, putative 0.0053 0.0493 0.1753
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.0067
Brugia malayi hypothetical protein 0.0021 0.0099 0.0231
Echinococcus multilocularis Peptidase S8 S53, subtilisin kexin sedolisin 0.0015 0.0015 0.0015
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0096 0.1035 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0053 0.0493 0.0493
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0081 0.0854 0.308
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0028 0.0104
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0028 0.0058
Trichomonas vaginalis aldo-keto reductase, putative 0.0053 0.0493 0.1753
Loa Loa (eye worm) endoprotease bli-4 0.0344 0.4165 0.9783
Echinococcus granulosus Mastin 0.0019 0.0065 0.0134
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0024 0.0131 0.027
Brugia malayi orphan nuclear receptor NR2E1 0.0021 0.0099 0.0231
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0045 0.0399 0.0938
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0023 0.0125 0.0258
Schistosoma mansoni hypothetical protein 0.0019 0.0065 0.0134
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0065 0.0134
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0351 0.4258 1
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0669 0.24
Echinococcus granulosus Nuclear hormone receptor HR96 0.0021 0.0099 0.0204
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0347 0.1219
Plasmodium falciparum aldehyde reductase, putative 0.0031 0.0217 0.1634
Schistosoma mansoni aldo-keto reductase 0.0053 0.0493 0.1018
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0031 0.0221 0.0519
Trichomonas vaginalis aldo-keto reductase, putative 0.0053 0.0493 0.1753
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0028 0.0104
Schistosoma mansoni hypothetical protein 0.004 0.0329 0.0679
Mycobacterium ulcerans oxidoreductase 0.0053 0.0493 1
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0669 0.24
Onchocerca volvulus 0.0053 0.0493 0.1799
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0053 0.0493 0.3864
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0045 0.0399 0.0826
Echinococcus multilocularis Tolloid protein 1 0.0016 0.0029 0.0029
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0045 0.0399 0.0938
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0217 0.0741
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0045 0.0399 0.0826
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0045 0.0399 0.0938
Trichomonas vaginalis aldo-keto reductase, putative 0.0053 0.0493 0.1753
Loa Loa (eye worm) hypothetical protein 0.0031 0.0221 0.0519
Brugia malayi hypothetical protein 0.0024 0.0131 0.0307
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0045 0.0399 0.0938
Trichomonas vaginalis hypothetical protein 0.0066 0.0669 0.24
Leishmania major hypothetical protein, conserved 0.0113 0.1251 1
Onchocerca volvulus 0.0053 0.0493 0.1799
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.0066 0.0669 0.24
Brugia malayi nuclear hormone receptor 0.0021 0.0099 0.0231
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0053 0.0493 0.3864
Schistosoma mansoni patched 1 0.0041 0.0347 0.0718
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0053 0.0493 0.0493
Echinococcus multilocularis GPCR, family 2 0.0031 0.0221 0.0221
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0203 0.0203
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.0066 0.0669 0.24
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0319 0.066
Brugia malayi endoprotease bli-4 precursor 0.0344 0.4165 0.9783
Echinococcus granulosus slit 2 protein 0.003 0.0206 0.0426
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0209 0.2465 0.8998
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0669 0.24
Schistosoma mansoni hypothetical protein 0.0067 0.0675 0.1394
Plasmodium falciparum aldo-keto reductase, putative 0.0031 0.0217 0.1634
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0045 0.0399 0.0938
Schistosoma mansoni retinoic acid receptor RXR 0.0045 0.0399 0.0826
Echinococcus granulosus aldo keto reductase family 1, member B4 0.0031 0.0217 0.0449
Brugia malayi nuclear hormone receptor family member odr-7 0.0021 0.0099 0.0231
Echinococcus multilocularis neuroendocrine convertase 2 0.0216 0.2554 0.2554
Loa Loa (eye worm) hypothetical protein 0.0019 0.0065 0.0152
Loa Loa (eye worm) hypothetical protein 0.0024 0.013 0.0306
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0024 0.0131 0.0307
Loa Loa (eye worm) hypothetical protein 0.0021 0.0099 0.0231
Loa Loa (eye worm) hypothetical protein 0.005 0.0464 0.1089
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0053 0.0493 0.1018
Schistosoma mansoni nuclear receptor nhr-48 0.0021 0.0099 0.0204
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0019 0.0065 0.0134
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0045 0.0399 0.0826
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0016 0.0029 0.0067
Brugia malayi laminin alpha chain 0.0024 0.013 0.0306
Loa Loa (eye worm) T-complex protein 1 0.0023 0.0125 0.0293
Trichomonas vaginalis aldo/keto reductase, putative 0.0053 0.0493 0.1753
Echinococcus multilocularis Furin 1 0.0081 0.0854 0.0854
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0065 0.0134
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0045 0.0399 0.0938
Mycobacterium ulcerans hypothetical protein 0.0031 0.0217 0.4228
Brugia malayi Nuclear hormone receptor-like 1 0.0045 0.0399 0.0938
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0045 0.0399 0.0938
Brugia malayi nuclear hormone receptor 0.0045 0.0399 0.0938
Echinococcus granulosus aldo keto reductase 0.0053 0.0493 0.1018
Loa Loa (eye worm) oxidoreductase 0.0053 0.0493 0.1157
Brugia malayi nuclear receptor RXR 0.0024 0.0131 0.0307
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0065 0.0134
Echinococcus granulosus neuroendocrine convertase 2 0.0216 0.2554 0.528
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0045 0.0399 0.0826
Brugia malayi nuclear receptor RXR 0.0021 0.0099 0.0231
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0065 0.0134
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0016 0.0029 0.0059
Echinococcus multilocularis aldo keto reductase 0.0053 0.0493 0.0493
Echinococcus granulosus aldehyde reductase 0.0022 0.0105 0.0218
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0065 0.0134
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0065 0.0134
Schistosoma mansoni thyroid hormone receptor 0.0045 0.0399 0.0826
Onchocerca volvulus 0.0019 0.0065 0.0236
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0113 0.1251 1
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0016 0.0029 0.0067
Schistosoma mansoni hypothetical protein 0.0066 0.0669 0.1382
Loa Loa (eye worm) hypothetical protein 0.003 0.0203 0.0477
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0021 0.0099 0.0204
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0039 0.0319 0.2135
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0217 0.0741
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0053 0.0493 0.1157
Loa Loa (eye worm) trypsin family protein 0.0019 0.0065 0.0152
Mycobacterium ulcerans hypothetical protein 0.0019 0.0065 0.1035
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0203 0.0203
Brugia malayi Trypsin-like protease protein 5 0.0019 0.0065 0.0152
Plasmodium vivax oxidoreductase, aldo/keto reductase domain containing protein 0.0031 0.0217 0.1634
Loa Loa (eye worm) hypothetical protein 0.0045 0.0399 0.0938
Entamoeba histolytica hypothetical protein 0.0036 0.0281 0.1717
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0053 0.0493 0.1018
Trichomonas vaginalis aldo-keto reductase, putative 0.0053 0.0493 0.1753
Schistosoma mansoni hypothetical protein 0.004 0.0329 0.0679
Schistosoma mansoni aldo-keto reductase 0.0053 0.0493 0.1018
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0065 0.0134
Brugia malayi nuclear receptor NHR-88 0.0045 0.0399 0.0938
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0347 0.0718
Trichomonas vaginalis aldo-keto reductase, putative 0.0053 0.0493 0.1753
Echinococcus multilocularis glycoprotein Antigen 5 0.0019 0.0065 0.0065
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0045 0.0399 0.0938
Loa Loa (eye worm) hypothetical protein 0.0113 0.1251 0.2937
Onchocerca volvulus 0.0053 0.0493 0.1799
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0045 0.0399 0.0938
Echinococcus multilocularis aldo keto reductase 0.0053 0.0493 0.0493
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0016 0.0029 0.0067
Giardia lamblia Aldose reductase 0.0053 0.0493 0.2794
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0045 0.0399 0.0826
Trypanosoma brucei T-complex protein 1, beta subunit, putative 0.0023 0.0125 0.2296
Trypanosoma cruzi T-complex protein 1, beta subunit, putative 0.0023 0.0125 0.0887
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0045 0.0399 0.0826
Echinococcus granulosus laminin 0.0016 0.0029 0.0059
Trichomonas vaginalis aldo-keto reductase, putative 0.0053 0.0493 0.1753
Echinococcus granulosus FTZ F1 alpha 0.0045 0.0399 0.0826
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0065 0.0134
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0024 0.0131 0.027
Loa Loa (eye worm) hypothetical protein 0.0021 0.0099 0.0231
Mycobacterium leprae Conserved hypothetical protein 0.0022 0.0105 0.189
Brugia malayi nuclear receptor NHR-88 0.0021 0.0099 0.0231
Loa Loa (eye worm) nuclear hormone receptor 0.0021 0.0099 0.0231
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0031 0.0221 0.0457
Loa Loa (eye worm) hypothetical protein 0.0019 0.0065 0.0152
Schistosoma mansoni hypothetical protein 0.0019 0.0065 0.0134
Loa Loa (eye worm) oxidoreductase 0.0053 0.0493 0.1157
Echinococcus granulosus furin 0.0344 0.4165 0.861
Loa Loa (eye worm) hypothetical protein 0.0021 0.0099 0.0231
Toxoplasma gondii oxidoreductase, aldo/keto reductase family protein 0.0031 0.0217 0.1634
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0081 0.0854 0.1765
Schistosoma mansoni steroid hormone receptor ad4bp 0.0045 0.0399 0.0826
Mycobacterium tuberculosis Conserved protein 0.0031 0.0217 0.4228
Loa Loa (eye worm) hypothetical protein 0.0039 0.0319 0.075
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0319 0.6369
Giardia lamblia High cysteine membrane protein Group 2 0.0128 0.1441 1
Brugia malayi Protein kinase domain containing protein 0.0113 0.1251 0.2937
Echinococcus multilocularis expressed conserved protein 0.009 0.0962 0.0962
Echinococcus granulosus ubiquitin specific protease 41 0.0039 0.0319 0.066
Echinococcus granulosus dnaJ subfamily B 0.0397 0.4838 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0045 0.0399 0.0826
Echinococcus multilocularis Niemann Pick C1 protein 0.0137 0.1553 0.1553
Onchocerca volvulus 0.0019 0.0065 0.0236
Onchocerca volvulus 0.0019 0.0065 0.0236
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0019 0.0065 0.0134
Echinococcus multilocularis fibrillin 1 0.0016 0.0029 0.0029
Toxoplasma gondii calcium binding egf domain-containing protein 0.0016 0.0029 0.0109
Schistosoma mansoni nuclear receptor 0.0021 0.0099 0.0204
Echinococcus granulosus aldo keto reductase 0.0053 0.0493 0.1018
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0028 0.0269
Echinococcus multilocularis aldehyde reductase 0.0022 0.0105 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0669 0.24
Schistosoma mansoni RAR-like nuclear receptor 0.0045 0.0399 0.0826
Plasmodium vivax SET domain protein, putative 0.003 0.0203 0.1521
Plasmodium vivax aldehyde reductase, putative 0.0031 0.0217 0.1634
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0099 0.0204
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.0067
Trichomonas vaginalis aldo-keto reductase, putative 0.0053 0.0493 0.1753
Echinococcus multilocularis enteropeptidase 0.0019 0.0065 0.0065
Echinococcus multilocularis membrane bound transcription factor site 1 0.0015 0.0015 0.0015
Toxoplasma gondii aldose reductase, putative 0.0053 0.0493 0.3864
Echinococcus granulosus expressed conserved protein 0.009 0.0962 0.1989
Loa Loa (eye worm) hypothetical protein 0.0024 0.0131 0.0307
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0097 0.1054 0.2179
Echinococcus multilocularis Niemann Pick C1 protein 0.0096 0.1035 0.1035
Loa Loa (eye worm) hypothetical protein 0.0045 0.0399 0.0938
Giardia lamblia Aldose reductase 0.0053 0.0493 0.2794
Trichomonas vaginalis aldo-keto reductase, putative 0.0053 0.0493 0.1753
Brugia malayi glutamate-cysteine ligase modifier subunit 0.0031 0.0217 0.051
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0065 0.0065
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0053 0.0493 0.0493
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0045 0.0399 0.0938
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0028 0.0028
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0589 0.1218
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0028 0.0066
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0021 0.0099 0.0099
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0351 0.4258 0.8802
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0203 0.042
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0028 0.0028
Entamoeba histolytica alcohol dehydrogenase, putative 0.0031 0.0217 0.1013
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0053 0.0493 0.0493
Schistosoma mansoni hypothetical protein 0.0036 0.0281 0.0581
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0028 0.0269
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0081 0.0854 0.308
Loa Loa (eye worm) hypothetical protein 0.0019 0.0065 0.0152
Brugia malayi hypothetical protein 0.0036 0.0281 0.066
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0045 0.0399 0.0938
Loa Loa (eye worm) hypothetical protein 0.0045 0.0399 0.0938
Brugia malayi CXXC zinc finger family protein 0.0028 0.0182 0.0426
Loa Loa (eye worm) proprotein convertase 2 0.0081 0.0854 0.2005
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0045 0.0399 0.0399
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0039 0.0319 0.1477
Schistosoma mansoni hypothetical protein 0.004 0.0329 0.0679
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0053 0.0493 0.0493
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0021 0.0099 0.0204
Brugia malayi Nuclear hormone receptor E75 0.0021 0.0099 0.0231
Trichomonas vaginalis alcohol dehydrogenase, putative 0.0031 0.0217 0.0741
Echinococcus granulosus tissue type plasminogen activator 0.0113 0.1251 0.2585
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.0067
Trypanosoma cruzi aldo/keto reductase, putative 0.0053 0.0493 0.3864
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0053 0.0493 0.1157
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0039 0.0319 0.1117
Loa Loa (eye worm) hypothetical protein 0.0096 0.1035 0.2431
Loa Loa (eye worm) hypothetical protein 0.0021 0.0099 0.0231
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0023 0.0125 0.0258
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0045 0.0399 0.0399
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0039 0.0319 0.0319
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0203 0.2386 0.5603
Echinococcus granulosus Furin 1 0.0081 0.0854 0.1765
Brugia malayi hypothetical protein 0.0021 0.0099 0.0231
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0053 0.0493 0.1753
Schistosoma mansoni tripeptidyl-peptidase II (S08 family) 0.0015 0.0015 0.0031
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0099 0.0204
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0669 0.24
Brugia malayi CHE-14 protein 0.0041 0.0347 0.0815
Brugia malayi Trypsin family protein 0.0019 0.0065 0.0152
Leishmania major prostaglandin f synthase, putative 0.0053 0.0493 0.3864
Loa Loa (eye worm) hypothetical protein 0.0045 0.0399 0.0938
Loa Loa (eye worm) hypothetical protein 0.0053 0.0493 0.1157
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0203 0.1521
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0347 0.0347
Brugia malayi Latrophilin receptor protein 2 0.0031 0.0221 0.0519
Schistosoma mansoni cell polarity protein 0.0024 0.013 0.0269
Echinococcus multilocularis tissue type plasminogen activator 0.0113 0.1251 0.1251
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0203 0.042
Loa Loa (eye worm) latrophilin receptor protein 2 0.0031 0.0221 0.0519
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0028 0.0104
Loa Loa (eye worm) hypothetical protein 0.0045 0.0399 0.0938
Brugia malayi neuroendocrine convertase 1 precursor 0.0216 0.2554 0.5999
Brugia malayi Subtilase family protein 0.0015 0.0015 0.0036
Loa Loa (eye worm) hypothetical protein 0.0019 0.0065 0.0152
Brugia malayi ecdysteroid receptor 0.0045 0.0399 0.0938
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0053 0.0493 0.1018
Schistosoma mansoni coup transcription factor 0.0045 0.0399 0.0826
Loa Loa (eye worm) hypothetical protein 0.0021 0.0099 0.0231
Onchocerca volvulus 0.0053 0.0493 0.1799
Echinococcus granulosus Tolloid protein 1 0.0016 0.0029 0.0059
Loa Loa (eye worm) hypothetical protein 0.0021 0.0099 0.0231
Mycobacterium tuberculosis Probable oxidoreductase 0.0053 0.0493 1
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0039 0.0319 0.2461
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0028 0.0104
Brugia malayi T-complex protein 1, beta subunit 0.0023 0.0125 0.0293
Echinococcus granulosus Nuclear hormone receptor HR96 0.0021 0.0099 0.0204
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0203 0.042
Trichomonas vaginalis aldo-keto reductase, putative 0.0053 0.0493 0.1753
Brugia malayi Pre-SET motif family protein 0.003 0.0203 0.0477
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0344 0.4165 0.861
Onchocerca volvulus 0.0015 0.0015 0.0056
Echinococcus multilocularis thyroid hormone receptor alpha 0.0045 0.0399 0.0399
Onchocerca volvulus 0.0031 0.0217 0.0793
Loa Loa (eye worm) hypothetical protein 0.0024 0.013 0.0306
Loa Loa (eye worm) hypothetical protein 0.003 0.0206 0.0484
Echinococcus granulosus nuclear receptor nhr 48 0.0021 0.0099 0.0204
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0065 0.0134
Loa Loa (eye worm) oxidoreductase 0.0053 0.0493 0.1157
Onchocerca volvulus Bile acid receptor homolog 0.0045 0.0399 0.1459
Loa Loa (eye worm) hypothetical protein 0.0021 0.0099 0.0231
Entamoeba histolytica aldose reductase, putative 0.0053 0.0493 0.4039
Onchocerca volvulus 0.0021 0.0099 0.036
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0203 0.042
Trichomonas vaginalis aldo-keto reductase, putative 0.0053 0.0493 0.1753
Schistosoma mansoni nuclear receptor 0.0021 0.0099 0.0204
Loa Loa (eye worm) oxidoreductase 0.0053 0.0493 0.1157
Entamoeba histolytica hypothetical protein 0.0036 0.0281 0.1717
Echinococcus multilocularis laminin 0.0016 0.0029 0.0029
Schistosoma mansoni hypothetical protein 0.0165 0.1905 0.3937
Trichomonas vaginalis chaperonin-60kD, ch60, putative 0.0023 0.0125 0.0403
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0024 0.0131 0.027
Leishmania major T-complex protein 1, beta subunit, putative 0.0023 0.0125 0.0887
Toxoplasma gondii aldo-keto reductase 0.0031 0.0217 0.1634
Onchocerca volvulus 0.0028 0.0182 0.0663
Onchocerca volvulus 0.0021 0.0099 0.036
Echinococcus granulosus aldo keto reductase 0.0053 0.0493 0.1018
Echinococcus granulosus GPCR family 2 0.0031 0.0221 0.0457
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0021 0.0099 0.0099
Loa Loa (eye worm) hypothetical protein 0.0045 0.0399 0.0938
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0045 0.0399 0.0938
Trypanosoma brucei aldo/keto reductase, putative 0.0031 0.0217 0.4228
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0021 0.0099 0.0099
Schistosoma mansoni hypothetical protein 0.0165 0.1905 0.3937
Onchocerca volvulus 0.0019 0.0065 0.0236
Trichomonas vaginalis aldo-keto reductase, putative 0.0053 0.0493 0.1753
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0053 0.0493 0.0493
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0045 0.0399 0.0938
Echinococcus multilocularis slit 2 protein 0.003 0.0206 0.0206
Echinococcus multilocularis protein dispatched 1 0.0047 0.042 0.042
Onchocerca volvulus 0.003 0.0203 0.0742
Schistosoma mansoni site-1 peptidase (S08 family) 0.0015 0.0015 0.0031
Plasmodium vivax T-complex protein 1 subunit beta, putative 0.0023 0.0125 0.0887
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0053 0.0493 0.0493
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0319 0.1117
Schistosoma mansoni hypothetical protein 0.004 0.0329 0.0679
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0099 0.0099
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0031 0.0221 0.0457
Loa Loa (eye worm) oxidoreductase 0.0053 0.0493 0.1157
Loa Loa (eye worm) steroid hormone receptor 0.0045 0.0399 0.0938
Brugia malayi Nuclear hormone receptor E75 0.0021 0.0099 0.0231
Loa Loa (eye worm) hypothetical protein 0.0045 0.0399 0.0938
Loa Loa (eye worm) hypothetical protein 0.0021 0.0099 0.0231
Onchocerca volvulus Protein ultraspiracle homolog 0.0045 0.0399 0.1459
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0021 0.0099 0.0231
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0203 0.042
Onchocerca volvulus 0.0045 0.0399 0.1459
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0099 0.0204
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0065 0.0134
Plasmodium falciparum T-complex protein 1 subunit beta 0.0023 0.0125 0.0887
Loa Loa (eye worm) hypothetical protein 0.0019 0.0065 0.0152
Echinococcus granulosus pikachurin 0.0024 0.013 0.0269
Loa Loa (eye worm) hypothetical protein 0.0015 0.0015 0.0036
Trichomonas vaginalis aldo-keto reductase, putative 0.0031 0.0217 0.0741
Schistosoma mansoni chaperonin containing t-complex protein 1 beta subunit tcpb 0.0023 0.0125 0.0258
Brugia malayi T-complex protein 1, beta subunit 0.0023 0.0125 0.0293
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0019 0.0065 0.0134
Schistosoma mansoni hypothetical protein 0.0031 0.0221 0.0457
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.0066 0.0669 0.24
Brugia malayi photoreceptor-specific nuclear receptor 0.0045 0.0399 0.0938
Echinococcus multilocularis voltage gated potassium channel subunit 0.0031 0.0217 0.0217
Schistosoma mansoni hypothetical protein 0.0031 0.0221 0.0457
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0045 0.0399 0.0938
Loa Loa (eye worm) hypothetical protein 0.0016 0.0029 0.0067
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0031 0.0221 0.0221
Brugia malayi ecdysone receptor 0.0021 0.0099 0.0231
Brugia malayi Calcitonin receptor-like protein seb-1 0.0098 0.1065 0.2502
Trichomonas vaginalis conserved hypothetical protein 0.0066 0.0669 0.24
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0039 0.0319 0.0319
Schistosoma mansoni cercarial elastase (S01 family) 0.0019 0.0065 0.0134
Echinococcus multilocularis aldo keto reductase 0.0053 0.0493 0.0493
Toxoplasma gondii t-complex protein beta subunit 0.0023 0.0125 0.0887
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0098 0.1065 0.2502
Loa Loa (eye worm) hypothetical protein 0.0135 0.153 0.3594
Entamoeba histolytica aldose reductase, putative 0.0053 0.0493 0.4039
Echinococcus multilocularis aldo keto reductase 0.0053 0.0493 0.0493
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0015 0.0015 0.0031
Schistosoma mansoni hypothetical protein 0.0113 0.1251 0.2585
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0053 0.0493 0.0493
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0045 0.0399 0.0938

Activities

Activity type Activity value Assay description Source Reference
Antifertility potency (functional) < 20 In vivo for antifertility potency in rat at 200 microg/Kg/day ChEMBL. 2738897
Estrogenic potency (functional) = 0.2 Compound was evaluated in vivo for estrogenic receptor potency relative to ethynylestradiol in rat . ChEMBL. 2738897

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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