Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.1844 | 0.1844 |
Brugia malayi | hypothetical protein | 0.0036 | 0.1844 | 0.1844 |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.1844 | 0.1844 |
Echinococcus granulosus | carboxylesterase 5A | 0.0111 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0111 | 1 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0111 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0019 | 0 | 0.5 |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.1844 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.1844 | 0.1844 |
Loa Loa (eye worm) | hypothetical protein | 0.0111 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0111 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0019 | 0 | 0.5 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0019 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.1844 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0111 | 1 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0019 | 0 | 0.5 |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.1844 | 0.1844 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.1844 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0111 | 1 | 1 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0019 | 0 | 0.5 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0019 | 0 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0111 | 1 | 1 |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Onchocerca volvulus | 0.0019 | 0 | 0.5 | |
Echinococcus multilocularis | carboxylesterase 5A | 0.0111 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0111 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0111 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.1844 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0111 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.