Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | glucosylceramidase, putative | 0.0183 | 0.0702 | 0.6391 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0108 | 0.0396 | 0.1197 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0279 | 0.1091 | 1 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0108 | 0.0396 | 0.1197 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0054 | 0.0178 | 0.0178 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0054 | 0.0178 | 0.0485 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0043 | 0.0134 | 0.0048 |
Brugia malayi | Dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.0697 | 0.2786 | 1 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0037 | 0.0133 |
Echinococcus multilocularis | ferritin | 0.0017 | 0.0029 | 0.0029 |
Schistosoma mansoni | hypothetical protein | 0.0019 | 0.0037 | 0.0112 |
Onchocerca volvulus | 0.0024 | 0.0055 | 0.0787 | |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0054 | 0.0178 | 0.0178 |
Brugia malayi | Muscleblind-like protein | 0.0595 | 0.2371 | 0.851 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0115 | 0.0424 | 0.0424 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.014 | 0.0423 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0272 | 0.1063 | 0.9743 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0193 | 0.0742 | 0.6762 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0146 | 0.0553 | 0.0553 |
Echinococcus granulosus | RUN | 0.0019 | 0.0037 | 0.0101 |
Loa Loa (eye worm) | glutaminase | 0.0271 | 0.1058 | 0.4463 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0055 | 0.0198 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0065 | 0.0221 | 0.0795 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0019 | 0.0037 | 0.0022 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.014 | 0.0383 |
Loa Loa (eye worm) | histone methyltransferase | 0.0018 | 0.0032 | 0.0136 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0279 | 0.1091 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0109 | 0.04 | 0.3416 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0216 | 0.0834 | 0.228 |
Brugia malayi | Dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.0697 | 0.2786 | 1 |
Plasmodium vivax | dihydroorotate dehydrogenase, mitochondrial precursor, putative | 0.0697 | 0.2786 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0055 | 0.0095 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0024 | 0.0055 | 0.0102 |
Mycobacterium ulcerans | dihydroorotate dehydrogenase 2 | 0.0697 | 0.2786 | 1 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.0697 | 0.2786 | 1 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0142 | 0.0537 | 0.1466 |
Echinococcus granulosus | muscleblind protein | 0.0595 | 0.2371 | 0.648 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0913 | 0.3659 | 0.3659 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0146 | 0.0553 | 0.1985 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.014 | 0.014 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0029 | 0.0088 |
Schistosoma mansoni | hypothetical protein | 0.0826 | 0.331 | 1 |
Brugia malayi | Zinc finger, C2H2 type family protein | 0.0272 | 0.1063 | 0.3816 |
Echinococcus granulosus | ferritin | 0.0017 | 0.0029 | 0.0079 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0109 | 0.04 | 0.1092 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0279 | 0.1091 | 0.3915 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0018 | 0.0031 | 0.0014 |
Onchocerca volvulus | 0.0047 | 0.0151 | 0.2153 | |
Schistosoma mansoni | sex comb on midleg homolog | 0.0047 | 0.0151 | 0.0457 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0204 | 0.0788 | 0.3322 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0355 | 0.1401 | 0.5027 |
Leishmania major | hypothetical protein, conserved | 0.0108 | 0.0396 | 0.1248 |
Loa Loa (eye worm) | hypothetical protein | 0.0595 | 0.2371 | 1 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0108 | 0.0396 | 0.1331 |
Schistosoma mansoni | cpg binding protein | 0.0061 | 0.0208 | 0.0629 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0183 | 0.0702 | 0.6391 |
Brugia malayi | CHE-14 protein | 0.0042 | 0.013 | 0.0467 |
Brugia malayi | hypothetical protein | 0.0127 | 0.0474 | 0.1702 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0396 | 0.167 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.014 | 0.0423 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0014 | 0.0018 | 0.0049 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0043 | 0.0134 | 0.1125 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0279 | 0.1091 | 0.46 |
Mycobacterium tuberculosis | Probable dihydroorotate dehydrogenase PyrD | 0.0697 | 0.2786 | 1 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0121 | 0.0242 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0018 | 0.0031 | 0.0112 |
Treponema pallidum | bacterioferrin (TpF1) | 0.0017 | 0.0029 | 0.5 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.014 | 0.0528 | 0.0528 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0042 | 0.013 | 0.1089 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0183 | 0.0702 | 0.6391 |
Schistosoma mansoni | tar DNA-binding protein | 0.0134 | 0.0503 | 0.152 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0042 | 0.013 | 0.0356 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0183 | 0.0702 | 0.6391 |
Wolbachia endosymbiont of Brugia malayi | dihydroorotate dehydrogenase 2 | 0.0697 | 0.2786 | 1 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0037 | 0.0133 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0108 | 0.0396 | 0.1337 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0124 | 0.0375 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0329 | 0.1388 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.014 | 0.0383 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0186 | 0.0715 | 0.0715 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0123 | 0.0458 | 0.1385 |
Trypanosoma brucei | dihydroorotate dehydrogenase (fumarate) | 0.0697 | 0.2786 | 1 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0018 | 0.0031 | 0.5 |
Brugia malayi | beta-lactamase family protein | 0.0108 | 0.0396 | 0.1421 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0098 | 0.0357 | 0.2997 |
Echinococcus granulosus | dnaJ subfamily B | 0.0826 | 0.331 | 0.9046 |
Schistosoma mansoni | patched 1 | 0.0042 | 0.013 | 0.0393 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0018 | 0.0032 | 0.0088 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.0697 | 0.2786 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0221 | 0.0934 |
Echinococcus granulosus | GPCR family 2 | 0.0065 | 0.0221 | 0.0605 |
Echinococcus multilocularis | expressed protein | 0.0017 | 0.0029 | 0.0029 |
Schistosoma mansoni | rab6-interacting | 0.0019 | 0.0037 | 0.0112 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0055 | 0.0095 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0108 | 0.0396 | 0.1031 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0019 | 0.0037 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0355 | 0.1401 | 0.5906 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0019 | 0.0037 | 0.0101 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0065 | 0.0221 | 0.0221 |
Brugia malayi | hypothetical protein | 0.0109 | 0.04 | 0.1434 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0108 | 0.0396 | 0.167 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0031 | 0.0131 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0014 | 0.0018 | 0.0018 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0018 | 0.0032 | 0.0032 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0031 | 0.0131 |
Schistosoma mansoni | hypothetical protein | 0.0338 | 0.1331 | 0.402 |
Entamoeba histolytica | hypothetical protein | 0.0109 | 0.04 | 0.3416 |
Echinococcus multilocularis | protein patched | 0.0042 | 0.013 | 0.013 |
Toxoplasma gondii | ABC1 family protein | 0.0108 | 0.0396 | 0.1031 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0019 | 0.0037 | 0.0101 |
Mycobacterium tuberculosis | Conserved protein | 0.0108 | 0.0396 | 0.1337 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0108 | 0.0396 | 0.3556 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0183 | 0.0702 | 1 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0019 | 0.0037 | 0.0022 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0183 | 0.0702 | 0.6391 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0019 | 0.0037 | 0.0037 |
Brugia malayi | TAR-binding protein | 0.0134 | 0.0503 | 0.1806 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.004 | 0.0121 | 0.0334 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0279 | 0.1091 | 1 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0146 | 0.0553 | 0.1671 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0216 | 0.0834 | 0.0834 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0024 | 0.0055 | 0.0102 |
Onchocerca volvulus | Huntingtin homolog | 0.0127 | 0.0474 | 0.6756 |
Loa Loa (eye worm) | doublecortin family protein | 0.0019 | 0.0037 | 0.0156 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0108 | 0.0396 | 0.0396 |
Echinococcus granulosus | expressed conserved protein | 0.0092 | 0.0333 | 0.0911 |
Echinococcus granulosus | neuropeptide s receptor | 0.0913 | 0.3659 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0329 | 0.1388 |
Onchocerca volvulus | 0.0108 | 0.0396 | 0.5643 | |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0279 | 0.1091 | 1 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0054 | 0.0178 | 0.0537 |
Mycobacterium ulcerans | lipase LipD | 0.0108 | 0.0396 | 0.1331 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0055 | 0.0198 |
Schistosoma mansoni | tar DNA-binding protein | 0.0134 | 0.0503 | 0.152 |
Echinococcus multilocularis | tar DNA binding protein | 0.0134 | 0.0503 | 0.0503 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0024 | 0.0055 | 0.0095 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.014 | 0.0526 | 0.1886 |
Schistosoma mansoni | tar DNA-binding protein | 0.0134 | 0.0503 | 0.152 |
Brugia malayi | MH2 domain containing protein | 0.0118 | 0.0437 | 0.1567 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0039 | 0.0119 | 0.0637 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0042 | 0.013 | 0.0549 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.004 | 0.0121 | 0.0121 |
Leishmania major | dihydroorotate dehydrogenase | 0.0697 | 0.2786 | 1 |
Mycobacterium tuberculosis | Bacterioferritin BfrB | 0.0017 | 0.0029 | 0.0007 |
Schistosoma mansoni | inositol monophosphatase | 0.004 | 0.0121 | 0.0366 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0108 | 0.0396 | 0.1331 |
Schistosoma mansoni | dihydroorotate dehydrogenase | 0.0697 | 0.2786 | 0.8418 |
Loa Loa (eye worm) | acetyltransferase | 0.0146 | 0.0553 | 0.2333 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.004 | 0.0121 | 0.1007 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0014 | 0.0018 | 0.0018 |
Trichomonas vaginalis | esterase, putative | 0.0108 | 0.0396 | 0.3556 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.0474 | 0.1999 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0108 | 0.0396 | 0.3556 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.0055 | 0.0095 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0029 | 0.0088 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0108 | 0.0396 | 0.1337 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0043 | 0.0134 | 0.0048 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0018 | 0.0031 | 0.0007 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.014 | 0.0528 | 0.1443 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0151 | 0.0637 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0272 | 0.1063 | 0.9743 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0055 | 0.0233 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0108 | 0.0396 | 0.3556 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0043 | 0.0134 | 0.0374 |
Brugia malayi | AMP-binding enzyme family protein | 0.0024 | 0.0055 | 0.0198 |
Loa Loa (eye worm) | MBCTL1 | 0.0054 | 0.0178 | 0.0749 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0036 | 0.0104 | 0.028 |
Schistosoma mansoni | hypothetical protein | 0.0338 | 0.1331 | 0.402 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0396 | 0.167 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0065 | 0.0221 | 0.0934 |
Brugia malayi | Doublecortin family protein | 0.0019 | 0.0037 | 0.0133 |
Mycobacterium leprae | Probable dihydroorotate dehydrogenase PyrD | 0.0697 | 0.2786 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0108 | 0.0396 | 0.1031 |
Loa Loa (eye worm) | beta-lactamase | 0.0108 | 0.0396 | 0.167 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0272 | 0.1063 | 0.9743 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0039 | 0.0119 | 0.0321 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0108 | 0.0396 | 0.3556 |
Schistosoma mansoni | tar DNA-binding protein | 0.0134 | 0.0503 | 0.152 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0108 | 0.0396 | 0.1337 |
Mycobacterium ulcerans | hypothetical protein | 0.0108 | 0.0396 | 0.1331 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0047 | 0.0151 | 0.2153 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0124 | 0.0375 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0047 | 0.0151 | 0.0413 |
Echinococcus multilocularis | GPCR, family 2 | 0.0065 | 0.0221 | 0.0221 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0396 | 0.167 |
Trichomonas vaginalis | dihydropyrimidine dehydrogenase, putative | 0.0272 | 0.1063 | 0.9743 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0183 | 0.0702 | 0.6391 |
Plasmodium falciparum | dihydroorotate dehydrogenase | 0.0697 | 0.2786 | 1 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0098 | 0.0357 | 0.0357 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0272 | 0.1063 | 0.2906 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0193 | 0.0742 | 0.6762 |
Echinococcus multilocularis | expressed conserved protein | 0.0092 | 0.0333 | 0.0333 |
Mycobacterium leprae | Probable lipase LipE | 0.0108 | 0.0396 | 0.1331 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0047 | 0.0151 | 0.0457 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0029 | 0.0088 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0108 | 0.0396 | 0.1421 |
Echinococcus multilocularis | muscleblind protein | 0.0595 | 0.2371 | 0.2371 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0047 | 0.0151 | 0.0457 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0043 | 0.0134 | 0.0366 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0108 | 0.0396 | 0.1337 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0114 | 0.042 | 0.112 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0109 | 0.04 | 0.04 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0108 | 0.0396 | 0.1082 |
Trichomonas vaginalis | glutaminase, putative | 0.0271 | 0.1058 | 0.9697 |
Echinococcus multilocularis | tumor protein p63 | 0.0347 | 0.1365 | 0.1365 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.004 | 0.0121 | 0.1007 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0036 | 0.0104 | 0.0273 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0039 | 0.0119 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0288 | 0.1125 | 0.3399 |
Trypanosoma cruzi | dihydroorotate dehydrogenase, putative | 0.0272 | 0.1063 | 0.3535 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0124 | 0.0375 |
Schistosoma mansoni | polycystin 1-related | 0.0019 | 0.0037 | 0.0112 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0272 | 0.1063 | 0.9743 |
Mycobacterium ulcerans | beta-lactamase | 0.0108 | 0.0396 | 0.1331 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0031 | 0.0131 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0031 | 0.0131 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0396 | 0.167 |
Echinococcus granulosus | cpg binding protein | 0.0061 | 0.0208 | 0.0569 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0019 | 0.0037 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0169 | 0.0711 |
Onchocerca volvulus | 0.0058 | 0.0195 | 0.2773 | |
Schistosoma mansoni | eyes absent homolog | 0.0091 | 0.0329 | 0.0994 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0054 | 0.0178 | 0.0638 |
Echinococcus granulosus | expressed protein | 0.0017 | 0.0029 | 0.0079 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.004 | 0.0121 | 0.0334 |
Trypanosoma cruzi | dihydroorotate dehydrogenase (fumarate), putative | 0.0697 | 0.2786 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0396 | 0.167 |
Mycobacterium tuberculosis | Conserved protein | 0.0108 | 0.0396 | 0.1337 |
Schistosoma mansoni | inositol monophosphatase | 0.004 | 0.0121 | 0.0366 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0118 | 0.0437 | 0.1841 |
Schistosoma mansoni | glutaminase | 0.0271 | 0.1058 | 0.3197 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0042 | 0.013 | 0.0356 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.004 | 0.0121 | 0.1007 |
Entamoeba histolytica | hypothetical protein | 0.0109 | 0.04 | 0.3416 |
Schistosoma mansoni | hypothetical protein | 0.0109 | 0.04 | 0.1207 |
Echinococcus multilocularis | cpg binding protein | 0.0061 | 0.0208 | 0.0208 |
Schistosoma mansoni | ferritin light chain | 0.0017 | 0.0029 | 0.0088 |
Schistosoma mansoni | apoferritin-2 | 0.0017 | 0.0029 | 0.0088 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.01 | 0.0363 | 0.1098 |
Plasmodium vivax | hypothetical protein, conserved | 0.0108 | 0.0396 | 0.1325 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.014 | 0.0503 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0024 | 0.0055 | 0.0095 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0186 | 0.0715 | 0.1954 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.004 | 0.0121 | 0.0655 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.013 | 0.0549 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0054 | 0.0178 | 0.0485 |
Schistosoma mansoni | loxhd1 | 0.0019 | 0.0037 | 0.0112 |
Mycobacterium ulcerans | glutaminase | 0.0271 | 0.1058 | 0.3733 |
Brugia malayi | Inositol-1 | 0.004 | 0.0121 | 0.0435 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0134 | 0.0503 | 0.1806 |
Loa Loa (eye worm) | inositol-1 | 0.004 | 0.0121 | 0.0511 |
Schistosoma mansoni | ferritin | 0.0017 | 0.0029 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.0474 | 0.1999 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0109 | 0.04 | 0.1207 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0065 | 0.0221 | 0.0795 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0826 | 0.331 | 0.331 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0913 | 0.3659 | 0.3659 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0047 | 0.0151 | 0.0413 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0014 | 0.0018 | 0.0054 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0396 | 0.167 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0042 | 0.013 | 0.013 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0272 | 0.1063 | 0.1063 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0047 | 0.0151 | 0.0637 |
Brugia malayi | mbt repeat family protein | 0.0047 | 0.0151 | 0.0542 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0108 | 0.0396 | 0.1031 |
Echinococcus multilocularis | geminin | 0.0338 | 0.1331 | 0.1331 |
Onchocerca volvulus | 0.0051 | 0.0165 | 0.2352 | |
Trichomonas vaginalis | ferritin, putative | 0.0017 | 0.0029 | 0.0152 |
Onchocerca volvulus | 0.0019 | 0.0037 | 0.0527 | |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0108 | 0.0396 | 0.1337 |
Onchocerca volvulus | 0.0019 | 0.0037 | 0.0527 | |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0688 | 0.2749 | 0.9866 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0272 | 0.1063 | 0.2906 |
Mycobacterium tuberculosis | Probable bacterioferritin BfrA | 0.0017 | 0.0029 | 0.0007 |
Entamoeba histolytica | dihydropyrimidine dehydrogenase, putative | 0.0272 | 0.1063 | 1 |
Brugia malayi | mbt repeat family protein | 0.0047 | 0.0151 | 0.0542 |
Loa Loa (eye worm) | TAR-binding protein | 0.0134 | 0.0503 | 0.2122 |
Loa Loa (eye worm) | hypothetical protein | 0.0595 | 0.2371 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0221 | 0.0669 |
Toxoplasma gondii | dihydroorotate dehydrogenase reveal, putative | 0.0697 | 0.2786 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0221 | 0.0669 |
Brugia malayi | CXXC zinc finger family protein | 0.0058 | 0.0195 | 0.0699 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.0055 | 0.0095 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.014 | 0.014 |
Schistosoma mansoni | hypothetical protein | 0.014 | 0.0526 | 0.1588 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0221 | 0.0669 |
Brugia malayi | beta-lactamase | 0.0108 | 0.0396 | 0.1421 |
Onchocerca volvulus | 0.0108 | 0.0396 | 0.5643 | |
Entamoeba histolytica | hypothetical protein | 0.0109 | 0.04 | 0.3416 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0272 | 0.1063 | 0.1063 |
Echinococcus multilocularis | protein dispatched 1 | 0.0048 | 0.0154 | 0.0154 |
Schistosoma mansoni | ferritin light chain | 0.0017 | 0.0029 | 0.0088 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0124 | 0.0375 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0024 | 0.0055 | 0.0095 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0037 | 0.0156 |
Onchocerca volvulus | 0.0108 | 0.0396 | 0.5643 | |
Echinococcus multilocularis | muscleblind protein 1 | 0.0595 | 0.2371 | 0.2371 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0024 | 0.0055 | 0.0095 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0279 | 0.1091 | 1 |
Brugia malayi | RNA binding protein | 0.0134 | 0.0503 | 0.1806 |
Brugia malayi | hypothetical protein | 0.0091 | 0.0329 | 0.1181 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0014 | 0.0018 | 0.0049 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0037 | 0.0156 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0031 | 0.0131 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.004 | 0.0121 | 0.0331 |
Schistosoma mansoni | cpg binding protein | 0.0058 | 0.0195 | 0.0588 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0047 | 0.0151 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0357 | 0.1507 |
Echinococcus granulosus | tar DNA binding protein | 0.0134 | 0.0503 | 0.1375 |
Onchocerca volvulus | Huntingtin homolog | 0.0127 | 0.0474 | 0.6756 |
Loa Loa (eye worm) | glutaminase 2 | 0.0271 | 0.1058 | 0.4463 |
Mycobacterium tuberculosis | Conserved protein | 0.0108 | 0.0396 | 0.1337 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0051 | 0.0165 | 0.0499 |
Schistosoma mansoni | tar DNA-binding protein | 0.0134 | 0.0503 | 0.152 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0098 | 0.0357 | 0.1282 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.014 | 0.0591 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0115 | 0.0424 | 0.1158 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0019 | 0.0037 | 0.0101 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0047 | 0.0151 | 0.0151 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0134 | 0.0503 | 0.2122 |
Brugia malayi | glutaminase DH11.1 | 0.0271 | 0.1058 | 0.3798 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0204 | 0.0788 | 0.2827 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0098 | 0.0357 | 0.0976 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0183 | 0.0702 | 0.6391 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0108 | 0.0396 | 0.3556 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0065 | 0.0221 | 0.0605 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0913 | 0.3659 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.014 | 0.0423 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0279 | 0.1091 | 1 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0108 | 0.0396 | 0.1337 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0108 | 0.0396 | 0.1337 |
Echinococcus granulosus | geminin | 0.0338 | 0.1331 | 0.3637 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.0526 | 0.2217 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0118 | 0.0437 | 0.1841 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0055 | 0.0233 |
Echinococcus granulosus | tumor protein p63 | 0.0347 | 0.1365 | 0.3729 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.0055 | 0.0095 |
Schistosoma mansoni | rab6-interacting | 0.0019 | 0.0037 | 0.0112 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0178 | 0.0749 |
Schistosoma mansoni | cpg binding protein | 0.0061 | 0.0208 | 0.0629 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0043 | 0.0134 | 0.1125 |
Echinococcus multilocularis | RUN | 0.0019 | 0.0037 | 0.0037 |
Loa Loa (eye worm) | RNA binding protein | 0.0134 | 0.0503 | 0.2122 |
Mycobacterium ulcerans | hypothetical protein | 0.0024 | 0.0055 | 0.0095 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0272 | 0.1063 | 0.9743 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0055 | 0.0233 |
Schistosoma mansoni | hypothetical protein | 0.0065 | 0.0221 | 0.0669 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0058 | 0.0195 | 0.0821 |
Schistosoma mansoni | lipoxygenase | 0.008 | 0.0284 | 0.0858 |
Brugia malayi | beta-lactamase family protein | 0.0108 | 0.0396 | 0.1421 |
Schistosoma mansoni | lipoxygenase | 0.0115 | 0.0424 | 0.128 |
Mycobacterium leprae | conserved hypothetical protein | 0.0108 | 0.0396 | 0.1331 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0165 | 0.0696 |
Schistosoma mansoni | apoferritin-2 | 0.0017 | 0.0029 | 0.0088 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.