Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0243 | 0.0449 |
Onchocerca volvulus | 0.0043 | 0.0127 | 0.0673 | |
Brugia malayi | PHD-finger family protein | 0.0026 | 0.0017 | 0.0008 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0132 | 0.0721 | 0.0721 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0193 | 0.1126 | 0.1126 |
Giardia lamblia | PHD finger protein 15 | 0.0029 | 0.0034 | 0.0123 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0142 | 0.0786 | 0.5099 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0079 | 0.0196 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.006 | 0.024 | 0.0498 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0095 | 0.0241 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0095 | 0.0179 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0048 | 0.0159 | 0.0159 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0043 | 0.0127 | 0.025 |
Trichomonas vaginalis | set domain proteins, putative | 0.0236 | 0.1409 | 0.4113 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0141 | 0.0782 | 0.1688 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0091 | 0.0445 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0038 | 0.0095 | 0.0053 |
Onchocerca volvulus | 0.0043 | 0.0127 | 0.0673 | |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0038 | 0.0094 | 0.0094 |
Onchocerca volvulus | 0.0093 | 0.0462 | 0.3107 | |
Loa Loa (eye worm) | hypothetical protein | 0.0364 | 0.2259 | 0.4927 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0043 | 0.0127 | 0.0289 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0095 | 0.0179 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0036 | 0.0079 | 0.0196 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0043 | 0.0127 | 0.0127 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0048 | 0.0159 | 0.0159 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0038 | 0.0094 | 0.0094 |
Schistosoma mansoni | glutaminase | 0.0537 | 0.3408 | 0.3408 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0029 | 0.0034 | 0.0034 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0051 | 0.0181 | 0.0181 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0193 | 0.1126 | 0.1126 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0029 | 0.0034 | 0.0034 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0095 | 0.0473 | 0.0473 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0146 | 0.0814 | 1 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0051 | 0.0181 | 0.0681 |
Brugia malayi | Bromodomain containing protein | 0.0079 | 0.0369 | 0.0781 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.0568 | 0.1218 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0095 | 0.0179 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0207 | 0.1219 | 0.2646 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0039 | 0.0039 |
Loa Loa (eye worm) | hypothetical protein | 0.0193 | 0.1126 | 0.2442 |
Brugia malayi | Hydroxymethylglutaryl-coenzyme A reductase family protein | 0.0469 | 0.2961 | 0.6469 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0146 | 0.0814 | 0.2171 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.005 | 0.0171 | 0.0348 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0043 | 0.0127 | 0.025 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0038 | 0.0095 | 0.0053 |
Onchocerca volvulus | 0.0043 | 0.0127 | 0.0673 | |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0035 | 0.0075 | 0.0075 |
Loa Loa (eye worm) | hypothetical protein | 0.0469 | 0.2961 | 0.6469 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0091 | 0.0445 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0095 | 0.0179 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0039 | 0.0039 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.0359 | 0.0798 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0043 | 0.0127 | 0.3297 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0039 | 0.0039 |
Brugia malayi | Pre-SET motif family protein | 0.0207 | 0.1219 | 0.2646 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0261 | 0.0261 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0078 | 0.0359 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0043 | 0.0127 | 0.0098 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0291 | 0.1776 | 0.5193 |
Loa Loa (eye worm) | oxidoreductase | 0.0043 | 0.0127 | 0.025 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0063 | 0.0261 | 0.0261 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.0568 | 0.1218 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0043 | 0.0127 | 0.0098 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0079 | 0.0196 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.0243 | 0.1138 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0038 | 0.0095 | 0.0053 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0243 | 0.0449 |
Brugia malayi | TAR-binding protein | 0.0063 | 0.0261 | 0.0544 |
Toxoplasma gondii | hypothetical protein | 0.0048 | 0.0162 | 0.4308 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0095 | 0.0179 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0142 | 0.0786 | 0.2088 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.005 | 0.0171 | 0.0348 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0043 | 0.0127 | 0.025 |
Brugia malayi | Bromodomain containing protein | 0.0032 | 0.0051 | 0.0084 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0193 | 0.1126 | 0.1126 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0038 | 0.0094 | 0.0094 |
Onchocerca volvulus | 0.0146 | 0.0814 | 0.567 | |
Brugia malayi | MH2 domain containing protein | 0.0119 | 0.0632 | 0.1358 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0038 | 0.0091 | 0.0091 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0291 | 0.1776 | 0.5193 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0043 | 0.0127 | 0.0336 |
Mycobacterium leprae | Probable lipase LipE | 0.0038 | 0.0095 | 0.0942 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0095 | 0.0095 |
Schistosoma mansoni | microtubule-associated protein tau | 0.1528 | 1 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0103 | 0.0528 | 0.3217 |
Brugia malayi | AMP-binding enzyme family protein | 0.0146 | 0.0814 | 0.1758 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0052 | 0.0188 | 0.0384 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0078 | 0.0359 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0291 | 0.1776 | 0.5193 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0043 | 0.0127 | 0.025 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.022 | 0.1305 | 0.3806 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0095 | 0.0473 | 0.0473 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.0034 | 0.0047 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0161 | 0.0914 | 0.1976 |
Brugia malayi | RNA binding protein | 0.0063 | 0.0261 | 0.0544 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0161 | 0.0914 | 0.0914 |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 0.0261 | 0.0544 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0043 | 0.0127 | 0.0098 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0146 | 0.0814 | 0.5299 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0043 | 0.0127 | 0.3297 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0109 | 0.0568 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0095 | 0.0241 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0034 | 0.0624 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0078 | 0.0359 | 0.6235 |
Onchocerca volvulus | 0.0043 | 0.0127 | 0.0673 | |
Schistosoma mansoni | alpha-glucosidase | 0.0139 | 0.0764 | 0.0764 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0193 | 0.1126 | 0.1126 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0043 | 0.0127 | 0.025 |
Echinococcus granulosus | peregrin | 0.0032 | 0.0051 | 0.0051 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0043 | 0.0127 | 0.0289 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0042 | 0.0121 | 0.0237 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0291 | 0.1776 | 1 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0066 | 0.0278 | 0.0583 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0193 | 0.1126 | 0.2442 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0038 | 0.0091 | 0.0091 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0034 | 0.0034 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0043 | 0.0127 | 0.025 |
Schistosoma mansoni | jumonji domain containing protein | 0.0076 | 0.0344 | 0.0344 |
Echinococcus multilocularis | protein patched | 0.0193 | 0.1126 | 0.1126 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0291 | 0.1776 | 1 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0043 | 0.0127 | 0.025 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.0359 | 0.6235 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0043 | 0.0127 | 0.025 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0109 | 0.0568 | 0.3506 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.0568 | 0.1218 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0034 | 0.0047 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0079 | 0.0196 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 0.0261 | 0.0544 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0066 | 0.0278 | 0.0583 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtF | 0.0043 | 0.0127 | 0.0098 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0299 | 0.1829 | 0.3984 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0146 | 0.0814 | 0.2171 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.0243 | 0.0243 |
Mycobacterium ulcerans | hydroxymethylglutaryl-coenzyme a (HMG-CoA) reductase | 0.0469 | 0.2961 | 0.8652 |
Brugia malayi | CHE-14 protein | 0.0193 | 0.1126 | 0.2442 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.0243 | 0.0506 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0157 | 0.0888 | 0.5841 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0043 | 0.0127 | 0.0098 |
Mycobacterium leprae | POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0043 | 0.0127 | 0.135 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.022 | 0.1305 | 0.3806 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0034 | 0.0067 | 0.0119 |
Brugia malayi | Cytochrome P450 family protein | 0.0052 | 0.0188 | 0.0384 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0261 | 0.0261 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.0814 | 0.1758 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0078 | 0.0359 | 0.4272 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0103 | 0.0528 | 0.3217 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0043 | 0.0127 | 0.0127 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0066 | 0.0278 | 0.0583 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.0711 | 0.457 | 1 |
Echinococcus granulosus | tumor protein p63 | 0.0735 | 0.4727 | 0.4727 |
Schistosoma mansoni | alpha glucosidase | 0.0036 | 0.0079 | 0.0079 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0043 | 0.0127 | 0.0098 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0043 | 0.0127 | 0.0336 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0079 | 0.0196 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0043 | 0.0127 | 0.0289 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0146 | 0.0814 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0171 | 0.0348 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0067 | 0.0067 |
Schistosoma mansoni | hypothetical protein | 0.0122 | 0.0656 | 0.0656 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0108 | 0.0557 | 0.0557 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0095 | 0.0179 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0043 | 0.0127 | 0.0098 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0146 | 0.0814 | 0.2171 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0079 | 0.0146 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0043 | 0.0127 | 0.0289 |
Onchocerca volvulus | 0.0038 | 0.0095 | 0.0437 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0193 | 0.1126 | 0.3278 |
Brugia malayi | AMP-binding enzyme family protein | 0.0043 | 0.0127 | 0.025 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0043 | 0.0127 | 0.0289 |
Brugia malayi | jmjC domain containing protein | 0.0037 | 0.0089 | 0.0166 |
Trypanosoma brucei | glucosidase, putative | 0.0036 | 0.0079 | 0.0146 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0261 | 0.0261 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0066 | 0.0278 | 0.0278 |
Brugia malayi | AMP-binding enzyme family protein | 0.0043 | 0.0127 | 0.025 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0036 | 0.0079 | 0.0146 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.005 | 0.0171 | 0.0348 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0029 | 0.0032 | 0.0032 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0043 | 0.0127 | 0.025 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0109 | 0.0568 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0109 | 0.0568 | 0.1429 |
Plasmodium falciparum | acetyl-CoA synthetase, putative | 0.0043 | 0.0127 | 0.2056 |
Leishmania major | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0469 | 0.2961 | 0.6469 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0038 | 0.0095 | 0.0053 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0119 | 0.0632 | 0.1358 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0193 | 0.1126 | 0.1126 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0339 | 0.0715 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0043 | 0.0127 | 0.0289 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.0359 | 0.5 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0243 | 0.0449 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0141 | 0.0282 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0036 | 0.0079 | 0.0079 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0079 | 0.0146 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0048 | 0.0159 | 0.0159 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0095 | 0.0179 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 0.0261 | 0.0544 |
Onchocerca volvulus | 0.0038 | 0.0095 | 0.0437 | |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0048 | 0.0159 | 0.0159 |
Loa Loa (eye worm) | beta-lactamase | 0.0038 | 0.0095 | 0.0179 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtE | 0.0043 | 0.0127 | 0.0098 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0243 | 0.0243 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0038 | 0.0095 | 0.0241 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0261 | 0.0261 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0103 | 0.0528 | 0.3217 |
Onchocerca volvulus | 0.0236 | 0.1409 | 1 | |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0043 | 0.0127 | 0.0098 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.0243 | 0.0243 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.1528 | 1 | 1 |
Echinococcus multilocularis | jumonji domain containing protein | 0.004 | 0.011 | 0.011 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0079 | 0.0377 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0161 | 0.0914 | 0.1976 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0146 | 0.0814 | 0.1758 |
Schistosoma mansoni | thyroid hormone receptor | 0.0132 | 0.0721 | 0.0721 |
Echinococcus multilocularis | peregrin | 0.0032 | 0.0051 | 0.0051 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0067 | 0.0119 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0029 | 0.0034 | 0.0047 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0141 | 0.0782 | 0.1688 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0043 | 0.0127 | 0.0289 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0243 | 0.1458 | 1 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0036 | 0.0079 | 0.0146 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0063 | 0.0261 | 0.0261 |
Echinococcus multilocularis | flap endonuclease 1 | 0.0026 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.0814 | 0.1758 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0091 | 0.0445 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0146 | 0.0814 | 0.5299 |
Leishmania major | hypothetical protein, conserved | 0.0038 | 0.0095 | 0.0179 |
Mycobacterium leprae | POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) | 0.0043 | 0.0127 | 0.135 |
Brugia malayi | hypothetical protein | 0.0038 | 0.0091 | 0.0172 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0078 | 0.0359 | 0.0359 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0066 | 0.0278 | 0.0583 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0038 | 0.0091 | 0.0091 |
Toxoplasma gondii | ABC1 family protein | 0.0038 | 0.0095 | 0.2361 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0291 | 0.1776 | 0.5193 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0079 | 0.0196 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.0568 | 0.1218 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0036 | 0.0079 | 0.0146 |
Onchocerca volvulus | 0.0108 | 0.0557 | 0.3798 | |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0066 | 0.0278 | 0.0583 |
Onchocerca volvulus | 0.0038 | 0.0095 | 0.0437 | |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0038 | 0.0095 | 0.0179 |
Brugia malayi | beta-lactamase | 0.0038 | 0.0095 | 0.0179 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0038 | 0.0095 | 0.0179 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0051 | 0.0181 | 0.2027 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0091 | 0.0091 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.0359 | 0.1932 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0291 | 0.1776 | 0.5193 |
Loa Loa (eye worm) | hypothetical protein | 0.0711 | 0.457 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0103 | 0.0528 | 0.3217 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0042 | 0.0121 | 0.0237 |
Schistosoma mansoni | patched 1 | 0.0193 | 0.1126 | 0.1126 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0261 | 0.0261 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0042 | 0.0121 | 0.0237 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0095 | 0.0053 |
Mycobacterium ulcerans | peptide synthetase Nrp (peptide synthase) | 0.0043 | 0.0127 | 0.0098 |
Schistosoma mansoni | bromodomain containing protein | 0.0067 | 0.0286 | 0.0286 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0051 | 0.0182 | 0.0371 |
Trichomonas vaginalis | esterase, putative | 0.0038 | 0.0095 | 0.0241 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0291 | 0.1776 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0146 | 0.0814 | 0.1758 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0078 | 0.0359 | 0.0359 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0043 | 0.0127 | 0.025 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0127 | 0.025 |
Brugia malayi | Bromodomain containing protein | 0.0041 | 0.0111 | 0.0215 |
Giardia lamblia | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 0.022 | 0.1305 | 0.733 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0359 | 0.076 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0037 | 0.0089 | 0.0089 |
Schistosoma mansoni | thyroid hormone receptor | 0.0132 | 0.0721 | 0.0721 |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 0.0261 | 0.0261 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0078 | 0.0359 | 0.0359 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0034 | 0.0624 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0111 | 0.0216 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0038 | 0.0095 | 0.0179 |
Brugia malayi | AMP-binding enzyme family protein | 0.0043 | 0.0127 | 0.025 |
Brugia malayi | AMP-binding enzyme family protein | 0.0146 | 0.0814 | 0.1758 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0036 | 0.0079 | 0.0196 |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0043 | 0.0127 | 0.0289 |
Leishmania major | long-chain-fatty-acid-CoA ligase, putative | 0.0043 | 0.0127 | 0.025 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.0469 | 0.2961 | 0.6469 |
Plasmodium vivax | hypothetical protein, conserved | 0.0038 | 0.0095 | 0.1472 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0043 | 0.0127 | 0.025 |
Schistosoma mansoni | hydroxymethylglutaryl-CoA reductase (NADPH) | 0.0469 | 0.2961 | 0.2961 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0043 | 0.0127 | 0.0289 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 0.0261 | 0.0544 |
Schistosoma mansoni | alpha-glucosidase | 0.0139 | 0.0764 | 0.0764 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0038 | 0.0095 | 0.0053 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0142 | 0.0786 | 0.9654 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0036 | 0.0079 | 0.0079 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0146 | 0.0814 | 0.1758 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0146 | 0.0814 | 0.2171 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0119 | 0.0632 | 0.1358 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0042 | 0.0121 | 0.0237 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0095 | 0.0179 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0066 | 0.0278 | 0.0583 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0127 | 0.025 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0038 | 0.0095 | 0.0095 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0039 | 0.0757 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0037 | 0.0089 | 0.0089 |
Brugia malayi | ERG2 and Sigma1 receptor like protein | 0.0711 | 0.457 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0291 | 0.1776 | 0.5193 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0095 | 0.0241 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0193 | 0.1126 | 0.1126 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0109 | 0.0568 | 1 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0299 | 0.1829 | 0.3984 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0146 | 0.0814 | 0.2171 |
Echinococcus multilocularis | tumor protein p63 | 0.0735 | 0.4727 | 0.4727 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0027 | 0.002 | 0.0125 |
Trichomonas vaginalis | glutaminase, putative | 0.0537 | 0.3408 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0128 | 0.0252 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0146 | 0.0814 | 0.2171 |
Echinococcus granulosus | hydroxymethylglutaryl coenzyme A reductase | 0.0469 | 0.2961 | 0.2961 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0161 | 0.0914 | 0.0914 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0557 | 0.1193 |
Echinococcus granulosus | jumonji domain containing protein | 0.004 | 0.011 | 0.011 |
Brugia malayi | glutaminase DH11.1 | 0.0537 | 0.3408 | 0.745 |
Plasmodium vivax | hypothetical protein, conserved | 0.0029 | 0.0034 | 0.0389 |
Mycobacterium leprae | conserved hypothetical protein | 0.0038 | 0.0095 | 0.0942 |
Mycobacterium ulcerans | glutaminase | 0.0537 | 0.3408 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0038 | 0.0094 | 0.0094 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0038 | 0.0095 | 0.0053 |
Echinococcus multilocularis | protein dispatched 1 | 0.0193 | 0.1126 | 0.1126 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0051 | 0.0181 | 0.0681 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0091 | 0.0445 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0038 | 0.0095 | 0.0095 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0291 | 0.1776 | 0.5193 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0043 | 0.0127 | 0.0098 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.0568 | 0.1218 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0299 | 0.1829 | 0.3984 |
Mycobacterium ulcerans | hypothetical protein | 0.0157 | 0.0888 | 0.2395 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.0814 | 0.1758 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0043 | 0.0127 | 0.0098 |
Trichomonas vaginalis | 3-hydroxy-3-methylglutaryl-coenzyme A reductase, putative | 0.022 | 0.1305 | 0.3806 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0095 | 0.0179 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0037 | 0.0089 | 0.0166 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0079 | 0.1922 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0095 | 0.0053 |
Brugia malayi | beta-lactamase family protein | 0.0038 | 0.0095 | 0.0179 |
Mycobacterium ulcerans | phenyloxazoline synthase MbtB | 0.0043 | 0.0127 | 0.0098 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 0.0261 | 0.0261 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0291 | 0.1776 | 1 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0066 | 0.0278 | 0.0278 |
Mycobacterium ulcerans | hypothetical protein | 0.0146 | 0.0814 | 0.2171 |
Loa Loa (eye worm) | glutaminase | 0.0537 | 0.3408 | 0.745 |
Mycobacterium ulcerans | long-chain-acyl-CoA synthetase | 0.0043 | 0.0127 | 0.0098 |
Mycobacterium ulcerans | O-succinylbenzoic acid--CoA ligase | 0.0043 | 0.0127 | 0.0098 |
Entamoeba histolytica | long-chain-fatty-acid--CoA ligase, putative | 0.0043 | 0.0127 | 0.0648 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0038 | 0.0095 | 0.0053 |
Leishmania major | C-8 sterol isomerase-like protein | 0.0711 | 0.457 | 1 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.0711 | 0.457 | 1 |
Mycobacterium leprae | Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) | 0.0043 | 0.0127 | 0.135 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0172 | 0.035 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0036 | 0.0079 | 0.0196 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0051 | 0.0181 | 0.0181 |
Brugia malayi | AMP-binding enzyme family protein | 0.0146 | 0.0814 | 0.1758 |
Mycobacterium ulcerans | acetyl-CoA synthetase | 0.0043 | 0.0127 | 0.0098 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0122 | 0.0656 | 0.0656 |
Trypanosoma brucei | 3-hydroxy-3-methylglutaryl-CoA reductase, putative | 0.0469 | 0.2961 | 0.6469 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.0243 | 0.6658 |
Brugia malayi | jmjC domain containing protein | 0.0095 | 0.0473 | 0.1011 |
Mycobacterium tuberculosis | Conserved protein | 0.0038 | 0.0095 | 0.0053 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0146 | 0.0814 | 0.4544 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0043 | 0.0127 | 0.0127 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0039 | 0.0058 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0039 | 0.0472 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0141 | 0.0782 | 0.1688 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0029 | 0.0034 | 0.0034 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.0359 | 0.0798 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0038 | 0.0095 | 0.0095 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0043 | 0.0127 | 0.0289 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0243 | 0.0243 |
Loa Loa (eye worm) | glutaminase 2 | 0.0537 | 0.3408 | 0.745 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0146 | 0.0814 | 0.2171 |
Plasmodium vivax | acetyl-CoA synthetase, putative | 0.0043 | 0.0127 | 0.2056 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0146 | 0.0814 | 0.4544 |
Brugia malayi | AMP-binding enzyme family protein | 0.0043 | 0.0127 | 0.025 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0038 | 0.0095 | 0.0241 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0037 | 0.0089 | 0.0089 |
Trypanosoma cruzi | 3-hydroxy-3-methylglutaryl-CoA reductase | 0.0469 | 0.2961 | 0.6469 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0291 | 0.1776 | 0.5193 |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0043 | 0.0127 | 0.025 |
Onchocerca volvulus | 0.003 | 0.0039 | 0.0034 | |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0043 | 0.0127 | 0.0289 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0036 | 0.0079 | 0.0377 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0036 | 0.0079 | 0.0196 |
Echinococcus granulosus | flap endonuclease 1 | 0.0026 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0159 | 0.0321 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0146 | 0.0814 | 0.4544 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0027 | 0.002 | 0.0125 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0066 | 0.0278 | 0.1506 |
Toxoplasma gondii | propionate-CoA ligase | 0.0043 | 0.0127 | 0.3297 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0122 | 0.0656 | 0.0656 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0161 | 0.0914 | 0.0914 |
Toxoplasma gondii | hypothetical protein | 0.0027 | 0.002 | 0.0201 |
Mycobacterium ulcerans | bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase | 0.0043 | 0.0127 | 0.0098 |
Echinococcus multilocularis | hydroxymethylglutaryl coenzyme A reductase | 0.0469 | 0.2961 | 0.2961 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0066 | 0.0278 | 0.0278 |
Brugia malayi | Probable ClpP-like protease | 0.0078 | 0.0359 | 0.076 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0299 | 0.1829 | 0.3984 |
Plasmodium falciparum | phd finger protein, putative | 0.0029 | 0.0034 | 0.0389 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.