Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0047 | 0.2763 | 0.8031 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.016 | 1 | 1 |
Trypanosoma brucei | protein kinase, putative | 0.0058 | 0.3441 | 1 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0047 | 0.2763 | 0.8031 |
Loa Loa (eye worm) | acetyltransferase | 0.016 | 1 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0058 | 0.3441 | 0.3441 |
Brugia malayi | MAP kinase sur-1 | 0.0058 | 0.3441 | 0.3441 |
Trichomonas vaginalis | histone acetyltransferase gcn5, putative | 0.0004 | 0.0036 | 0.0106 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0047 | 0.2763 | 0.8031 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0043 | 0.2512 | 0.7302 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0058 | 0.3441 | 1 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0047 | 0.2763 | 0.8031 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0058 | 0.3441 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.2984 | 0.2984 |
Onchocerca volvulus | Brd8 homolog | 0.0004 | 0 | 0.5 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0058 | 0.3441 | 1 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0047 | 0.2763 | 1 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0058 | 0.3441 | 0.3441 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0043 | 0.2512 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0058 | 0.3441 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.2984 | 0.3072 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.2984 | 0.2984 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0047 | 0.2763 | 0.2845 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.2984 | 0.2984 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0058 | 0.3441 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0058 | 0.3441 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0058 | 0.3441 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.2984 | 0.2984 |
Onchocerca volvulus | 0.0004 | 0 | 0.5 | |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0058 | 0.3441 | 0.3543 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.2984 | 0.2984 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0058 | 0.3441 | 1 |
Onchocerca volvulus | Bromodomain adjacent to zinc finger domain protein 1A homolog | 0.0004 | 0 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0058 | 0.3441 | 1 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.016 | 1 | 1 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0058 | 0.3441 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0058 | 0.3441 | 0.3441 |
Trichomonas vaginalis | histone acetyltransferase gcn5, putative | 0.0004 | 0.0036 | 0.0106 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0155 | 0.9713 | 1 |
Onchocerca volvulus | 0.0004 | 0 | 0.5 | |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.2984 | 0.3072 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0058 | 0.3441 | 1 |
Onchocerca volvulus | 0.0004 | 0 | 0.5 | |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0058 | 0.3441 | 1 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0058 | 0.3441 | 1 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0058 | 0.3441 | 0.3543 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.2984 | 0.2984 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0043 | 0.2512 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0058 | 0.3441 | 0.3441 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.2984 | 0.2984 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.