Detailed information for compound 647065

Basic information

Technical information
  • TDR Targets ID: 647065
  • Name: 2-[(2-methoxyphenyl)-phenylsulfonylamino]-N-[ 2-(4-methylphenyl)sulfanylethyl]acetamide
  • MW: 470.604 | Formula: C24H26N2O4S2
  • H donors: 1 H acceptors: 3 LogP: 4.52 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccccc1N(S(=O)(=O)c1ccccc1)CC(=O)NCCSc1ccc(cc1)C
  • InChi: 1S/C24H26N2O4S2/c1-19-12-14-20(15-13-19)31-17-16-25-24(27)18-26(22-10-6-7-11-23(22)30-2)32(28,29)21-8-4-3-5-9-21/h3-15H,16-18H2,1-2H3,(H,25,27)
  • InChiKey: GDDWCTZYXLKLHO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[(2-methoxyphenyl)-phenylsulfonyl-amino]-N-[2-(4-methylphenyl)sulfanylethyl]acetamide
  • 2-[(2-methoxyphenyl)-phenylsulfonylamino]-N-[2-[(4-methylphenyl)thio]ethyl]acetamide
  • 2-[(2-methoxyphenyl)-phenylsulfonyl-amino]-N-[2-[(4-methylphenyl)thio]ethyl]acetamide
  • 2-[(2-methoxyphenyl)-phenylsulfonyl-amino]-N-[2-(4-methylphenyl)sulfanylethyl]ethanamide
  • BAS 00754441
  • AG-690/12002100

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0059 0.0052
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.0032 0.005
Leishmania major hypothetical protein, conserved 0.0174 0.1922 0.364
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0044 0.0023
Brugia malayi hypothetical protein 0.0016 0.0063 0.0121
Trypanosoma cruzi NADPH-dependent FMN/FAD containing oxidoreductase, putative 0.0455 0.5223 1
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0059 0.0113
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0109 0.0209
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0014 0.0044 0.0084
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0109 0.0139
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0052 0.0484 0.0871
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0109 0.0109
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0049 0.0448 0.078
Schistosoma mansoni cathepsin F (C01 family) 0.0011 0.0006 0.0008
Echinococcus granulosus segment polarity protein dishevelled 0.0011 0.0003 0.0004
Brugia malayi Cathepsin L-like cysteine proteinase 0.0011 0.0006 0.0011
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0052 0.0484 0.0871
Echinococcus granulosus pdz domain containing protein 0.0011 0.0003 0.0004
Echinococcus multilocularis cell polarity protein leucine rich repeat 0.0011 0.0003 0.0003
Loa Loa (eye worm) 9ORF binding protein 1 0.0011 0.0003 0.0006
Brugia malayi microtubule-associated serine/threonine protein kinase 2 (MAST2) 0.0011 0.0003 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0032 0.005
Loa Loa (eye worm) histone methyltransferase 0.0018 0.0089 0.0171
Brugia malayi Cytochrome b5-like Heme/Steroid binding domain containing protein 0.0052 0.0484 0.0927
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0044 0.0503
Schistosoma mansoni acetyl-CoA synthetase 0.0014 0.0044 0.0056
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0044 0.0084
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0044 0.0084
Leishmania major cytochrome-b5 reductase, putative 0.0052 0.0484 0.0871
Plasmodium falciparum acyl-CoA synthetase 0.0036 0.0303 0.0581
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0109 0.0209
Brugia malayi C2 domain containing protein 0.0011 0.0003 0.0006
Schistosoma mansoni diflavin oxidoreductase 0.0226 0.2529 0.3219
Echinococcus multilocularis Na(+):H(+) exchange regulatory cofactor NHE RF2 0.0011 0.0003 0.0003
Echinococcus granulosus 55 kDa erythrocyte membrane protein 0.0011 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.002 0.0109 0.0209
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0032 0.005
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0109 0.1103
Schistosoma mansoni multiple pdz domain protein 0.0011 0.0003 0.0004
Schistosoma mansoni cell polarity protein 0.0011 0.0003 0.0004
Echinococcus granulosus cathepsin l1 0.0011 0.0006 0.0008
Entamoeba histolytica hypothetical protein 0.0038 0.0328 0.168
Echinococcus multilocularis cysteine protease 0.0016 0.007 0.007
Brugia malayi Cathepsin L-like precursor 0.0016 0.007 0.0134
Brugia malayi flavodoxin family protein 0.0174 0.1922 0.3679
Loa Loa (eye worm) ctsf protein 0.0016 0.007 0.0134
Schistosoma mansoni pdz domain containing protein 0.0011 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0455 0.5223 1
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0044 0.0084
Brugia malayi PDZ-domain protein scribble 0.0011 0.0003 0.0006
Brugia malayi Patj homolog 0.0011 0.0003 0.0006
Schistosoma mansoni MAGUK homolog 0.0011 0.0003 0.0004
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0455 0.5223 1
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0014 0.0044 0.0503
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0109 0.0209
Echinococcus granulosus SH3 and multiple ankyrin repeat domains protein 0.0011 0.0003 0.0004
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0018 0.0089 0.0113
Plasmodium vivax flavodoxin domain containing protein 0.0403 0.4615 0.8826
Schistosoma mansoni rab3 interacting molecule (rim)-related 0.0011 0.0003 0.0004
Trypanosoma brucei glucosidase, putative 0.0036 0.0294 0.0505
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0059 0.0029
Schistosoma mansoni hypothetical protein 0.0011 0.0003 0.0004
Toxoplasma gondii flavodoxin domain-containing protein 0.0226 0.2529 1
Echinococcus multilocularis PDZ and LIM domain protein Zasp 0.0011 0.0003 0.0003
Brugia malayi 9ORF binding protein 1 0.0011 0.0003 0.0006
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0014 0.0044 0.0174
Mycobacterium tuberculosis Possible electron transfer protein FdxB 0.0052 0.0484 1
Mycobacterium ulcerans flavodoxin reductase Hmp 0.0052 0.0484 0.085
Echinococcus granulosus 3'partial|membrane associated guanylate kinase ww and pdz 0.0011 0.0003 0.0004
Brugia malayi PDZ domain containing protein 0.0011 0.0003 0.0006
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0015 0.0047 0.006
Echinococcus multilocularis glutamate receptor interacting protein 1 0.0011 0.0003 0.0003
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0109 0.0209
Echinococcus multilocularis 0.0011 0.0003 0.0003
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.007 0.007
Trypanosoma cruzi reductase, putative 0.0052 0.0484 0.0871
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0036 0.0303 0.6099
Loa Loa (eye worm) X11 protein 0.0011 0.0003 0.0006
Echinococcus multilocularis cysteine protease 0.0016 0.007 0.007
Leishmania major cathepsin L-like protease 0.0016 0.007 0.0073
Schistosoma mansoni syntenin 0.0011 0.0003 0.0004
Leishmania major oxidoreductase-like protein 0.0052 0.0484 0.0871
Loa Loa (eye worm) diaphorase 0.0052 0.0484 0.0927
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0328 0.0328
Loa Loa (eye worm) FAD binding domain-containing protein 0.0281 0.3178 0.6084
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0109 0.0109
Echinococcus granulosus tumor protein p63 0.0332 0.3784 0.4816
Loa Loa (eye worm) fibroinase 0.0016 0.007 0.0134
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0109 0.0139
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0006 0.0006
Loa Loa (eye worm) oxidoreductase 0.0014 0.0044 0.0084
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0671 0.0854
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.007 0.0123
Echinococcus granulosus Partitioning defective 3 protein B 0.0011 0.0003 0.0004
Entamoeba histolytica hypothetical protein 0.0038 0.0328 0.168
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.007 0.0089
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0448 0.0801
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0011
Echinococcus granulosus disks large 1 0.0011 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0016 0.007 0.0134
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0052 0.0484 0.0871
Leishmania major cytochrome P450 reductase, putative 0.0403 0.4615 0.8829
Echinococcus multilocularis tight junction protein ZO 3 0.0011 0.0003 0.0003
Echinococcus multilocularis MAGUK p55 subfamily 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0025 0.0165 0.0317
Brugia malayi protein kinase C-binding protein PICK1 0.0011 0.0003 0.0006
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0165 0.0257
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0018 0.0089 0.0089
Entamoeba histolytica acyl-coA synthetase, putative 0.0049 0.0448 0.2307
Schistosoma mansoni cell polarity protein 0.0011 0.0003 0.0004
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.055 0.0998
Echinococcus granulosus PDZ and LIM domain protein Zasp 0.0011 0.0003 0.0004
Brugia malayi diaphorase 0.0052 0.0484 0.0927
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0671 0.0854
Toxoplasma gondii histone lysine methyltransferase SET1 0.0111 0.118 0.4664
Echinococcus granulosus cell polarity protein 0.0011 0.0003 0.0004
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0109 0.0139
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0011 0.0003 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.007 0.0123
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.028 0.5596
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.007 0.0123
Mycobacterium ulcerans flavodoxin oxidoreductase 0.0052 0.0484 0.085
Loa Loa (eye worm) hypothetical protein 0.0036 0.0303 0.0581
Echinococcus granulosus SH3 and multiple ankyrin repeat domains protein 0.0011 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Echinococcus multilocularis tumor protein p63 0.0332 0.3784 0.3784
Echinococcus multilocularis dnaJ subfamily B 0.0399 0.4569 0.4569
Leishmania major cathepsin L-like protease 0.0063 0.0614 0.1121
Brugia malayi RNA binding protein 0.0068 0.0671 0.1285
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0448 0.078
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0109 0.0109
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.176 0.176
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0294 0.0553
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0109 0.0139
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0294 0.1506
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0109 0.0139
Echinococcus granulosus multiple pdz domain protein 0.0011 0.0003 0.0004
Schistosoma mansoni hypothetical protein 0.0032 0.0257 0.0327
Giardia lamblia Hypothetical protein 0.0403 0.4615 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0614 0.1121
Echinococcus multilocularis peripheral plasma membrane protein CASK 0.0011 0.0003 0.0003
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0032 0.005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0614 0.1121
Trypanosoma cruzi cytochrome-b5 reductase, putative 0.0052 0.0484 0.0871
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0052 0.0484 0.0871
Echinococcus multilocularis NADH cytochrome b5 reductase 3 0.0052 0.0484 0.0484
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0011 0.0003 0.0004
Leishmania major cathepsin L-like protease 0.0016 0.007 0.0073
Onchocerca volvulus 0.0016 0.007 0.0696
Entamoeba histolytica type A flavoprotein, putative 0.0174 0.1922 1
Schistosoma mansoni leucine-rich repeat protein 0.0011 0.0003 0.0004
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0052 0.0484 0.0871
Loa Loa (eye worm) hypothetical protein 0.002 0.0109 0.0209
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0614 0.1121
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0044 0.0084
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0165 0.0234
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.007 0.0123
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0052 0.0484 0.0871
Echinococcus granulosus ligand of numb protein x 2 0.0011 0.0003 0.0004
Echinococcus granulosus tight junction protein ZO 3 0.0011 0.0003 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.007 0.0123
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0294 0.0564
Schistosoma mansoni afadin (af-6 protein) 0.0011 0.0003 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.007 0.0123
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Leishmania major NADH-dependent fumarate reductase, putative 0.0052 0.0484 0.0871
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0044 0.0023
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0257 0.0491
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0044 0.0023
Echinococcus granulosus partitioning defective 3 0.0011 0.0003 0.0004
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0044 0.0503
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0257 0.0327
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0174 0.1922 0.3672
Echinococcus granulosus partitioning defective 3 0.0011 0.0003 0.0004
Echinococcus multilocularis segment polarity protein dishevelled 0.0011 0.0003 0.0003
Echinococcus granulosus amyloid beta A4 protein 0.0011 0.0003 0.0004
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0036 0.0008
Schistosoma mansoni dishevelled 0.0011 0.0003 0.0004
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.007 0.0073
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0032 0.005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0614 0.1121
Onchocerca volvulus Cathepsin F homolog 0.0016 0.007 0.0696
Brugia malayi F/Y-rich N-terminus family protein 0.0018 0.0086 0.0165
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.007 0.0123
Leishmania major cathepsin L-like protease 0.0016 0.007 0.0073
Brugia malayi DIX domain containing protein 0.0011 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Echinococcus multilocularis partitioning defective protein 6 0.0011 0.0003 0.0003
Trypanosoma brucei NADH-dependent fumarate reductase 0.0052 0.0484 0.0871
Echinococcus multilocularis NADPH dependent diflavin oxidoreductase 1 0.0455 0.5223 0.5223
Echinococcus granulosus MAGUK p55 subfamily 0.0011 0.0003 0.0004
Trypanosoma cruzi cytochrome-b5 reductase, putative 0.0052 0.0484 0.0871
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0294 0.0294
Loa Loa (eye worm) PDZ-domain-containing protein scribble 0.0011 0.0003 0.0006
Brugia malayi RNA recognition motif domain containing protein 0.0068 0.0671 0.1285
Schistosoma mansoni cpg binding protein 0.0062 0.0604 0.0768
Toxoplasma gondii cathepsin CPL 0.0016 0.007 0.0276
Brugia malayi Cathepsin L-like precursor 0.0016 0.007 0.0134
Schistosoma mansoni tight junction protein 0.0011 0.0003 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.007 0.0123
Brugia malayi hypothetical protein 0.0038 0.0328 0.0627
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0011 0.000000000056343 0.00000000022275
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0032 0.005
Brugia malayi Syntrophin-1 0.0011 0.0003 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0109 0.0209
Mycobacterium ulcerans formate dehydrogenase H FdhF 0.0455 0.5223 1
Schistosoma mansoni hypothetical protein 0.0011 0.0003 0.0004
Echinococcus multilocularis glutamate receptor interacting protein 1 0.0011 0.0003 0.0003
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0059 0.0052
Schistosoma mansoni blooms syndrome DNA helicase 0.002 0.0113 0.0144
Loa Loa (eye worm) flavodoxin family protein 0.0174 0.1922 0.3679
Loa Loa (eye worm) hypothetical protein 0.0049 0.0448 0.0858
Schistosoma mansoni sap-97 0.0011 0.0003 0.0004
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0032 0.005
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.007 0.007
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.0011 0.0003 0.0004
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0032 0.005
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0052 0.0484 0.0871
Onchocerca volvulus 0.0052 0.0484 0.4997
Trypanosoma brucei nitrate reductase, putative 0.0052 0.0484 0.0871
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0059 0.0075
Schistosoma mansoni multiple pdz domain protein 0.0011 0.0003 0.0004
Echinococcus granulosus PDZ and LIM domain protein Zasp 0.0011 0.0003 0.0004
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0448 0.078
Echinococcus granulosus rho guanine nucleotide exchange factor 12 0.0011 0.0003 0.0004
Trichomonas vaginalis DNA helicase recq1, putative 0.0025 0.0176 0.0326
Brugia malayi nuclear hormone receptor 0.002 0.0109 0.0209
Loa Loa (eye worm) hypothetical protein 0.002 0.0109 0.0209
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0448 0.2307
Brugia malayi FAD binding domain containing protein 0.0455 0.5223 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0015 0.0047 0.0047
Trypanosoma brucei NADH-dependent fumarate reductase, putative 0.0052 0.0484 0.0871
Plasmodium vivax acyl-CoA synthetase, putative 0.0036 0.0303 0.0501
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0294 0.0553
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0109 0.0209
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0052 0.0484 0.0871
Brugia malayi Ferm domain 0.0011 0.0003 0.0006
Plasmodium falciparum cysteine proteinase falcipain 3 0.0016 0.007 0.0134
Onchocerca volvulus 0.0016 0.007 0.0696
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0032 0.005
Echinococcus granulosus GPCR family 2 0.0032 0.0257 0.0327
Loa Loa (eye worm) guanylate kinase 0.0011 0.0003 0.0006
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0068 0.0671 0.1285
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0455 0.5223 1
Schistosoma mansoni cpg binding protein 0.0062 0.0604 0.0768
Echinococcus granulosus cathepsin l cysteine peptidase 0.0016 0.007 0.0089
Echinococcus multilocularis neurabin 1 0.0011 0.0003 0.0003
Brugia malayi FAD binding domain containing protein 0.0281 0.3178 0.6084
Echinococcus multilocularis partitioning defective 3 0.0011 0.0003 0.0003
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0059 0.0052
Brugia malayi PDZ domain containing protein 0.0011 0.0003 0.0006
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0109 0.0209
Brugia malayi PDZ domain 0.0011 0.0003 0.0006
Echinococcus granulosus beta 1 syntrophin 0.0011 0.0003 0.0004
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0257 0.0257
Loa Loa (eye worm) hypothetical protein 0.007 0.0698 0.1336
Schistosoma mansoni hypothetical protein 0.0165 0.182 0.2317
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0448 0.0801
Loa Loa (eye worm) glutaminase 2 0.0267 0.3014 0.577
Schistosoma mansoni hypothetical protein 0.0011 0.0003 0.0004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0109 0.0209
Entamoeba histolytica hypothetical protein 0.0038 0.0328 0.168
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0448 0.0801
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0294 0.0505
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0294 0.1506
Brugia malayi gamma-syntrophin-like protein SYN2 0.0011 0.0003 0.0006
Schistosoma mansoni glutaminase 0.0267 0.3014 0.3836
Schistosoma mansoni hypothetical protein 0.0011 0.0006 0.0008
Echinococcus multilocularis membrane associated guanylate kinase, WW and PDZ 0.0011 0.0003 0.0003
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0102 0.1078 0.2064
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0044 0.0503
Brugia malayi nuclear receptor NHR-88 0.002 0.0109 0.0209
Trypanosoma brucei NADPH-dependent diflavin oxidoreductase 1 0.0455 0.5223 1
Giardia lamblia Flavohemoprotein lateral transfer candidate 0.0052 0.0484 0.1049
Mycobacterium ulcerans oxidoreductase 0.0052 0.0484 0.085
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0109 0.0139
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0044 0.0084
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0165 0.0317
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0059 0.0052
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0052 0.0484 0.0871
Loa Loa (eye worm) RecQ helicase 0.0025 0.0176 0.0337
Onchocerca volvulus 0.0016 0.007 0.0696
Echinococcus granulosus myeloid:lymphoid or mixed lineage leukemia 0.0011 0.0003 0.0004
Brugia malayi Peripheral plasma membrane protein CASK 0.0011 0.0003 0.0006
Mycobacterium ulcerans monooxygenase 0.0052 0.0484 0.085
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0013 0.0032 0.0302
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0109 0.0139
Schistosoma mansoni hypothetical protein 0.0011 0.0003 0.0004
Echinococcus multilocularis multiple pdz domain protein 0.0011 0.0003 0.0003
Brugia malayi CXXC zinc finger family protein 0.0059 0.0564 0.108
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0109 0.0139
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0671 0.0854
Schistosoma mansoni hypothetical protein 0.0038 0.0328 0.0417
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.007 0.0123
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0109 0.0209
Brugia malayi Abnormal embryonic partitioning of cytoplasm protein 3 0.0011 0.0003 0.0006
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0059 0.0059
Brugia malayi interleukin-16 0.0011 0.0003 0.0006
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0014 0.0044 0.0503
Schistosoma mansoni pdz domain containing protein 0.0011 0.0003 0.0004
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0044 0.0073
Echinococcus granulosus cathepsin l1 0.0016 0.007 0.0089
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0174 0.1922 0.3672
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.007 0.0123
Trypanosoma cruzi p450 reductase, putative 0.0455 0.5223 1
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0052 0.0484 0.0871
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.007 0.0123
Brugia malayi TAR-binding protein 0.0068 0.0671 0.1285
Loa Loa (eye worm) hypothetical protein 0.002 0.0109 0.0209
Onchocerca volvulus 0.0014 0.0044 0.0428
Plasmodium vivax ferredoxin--NADP reductase, putative 0.0052 0.0484 0.085
Echinococcus multilocularis partitioning defective 3 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0109 0.0209
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0448 0.0858
Brugia malayi Glycosyl hydrolases family 31 protein 0.0013 0.0032 0.0061
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0014 0.0044 0.0199
Brugia malayi hypothetical protein 0.0011 0.0003 0.0006
Trypanosoma cruzi NADPH--cytochrome P450 reductase, putative 0.0174 0.1922 0.364
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0109 0.0139
Leishmania major NADH-dependent fumarate reductase-like protein 0.0052 0.0484 0.0871
Brugia malayi isocitrate dehydrogenase 0.0016 0.0059 0.0113
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0294 0.0553
Leishmania major NADH-cytochrome b5 reductase, putative 0.0052 0.0484 0.0871
Echinococcus multilocularis segment polarity protein dishevelled 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Schistosoma mansoni maguk P55 subfamily member 35 0.0011 0.0003 0.0004
Trypanosoma cruzi p450 reductase, putative 0.0052 0.0484 0.0871
Loa Loa (eye worm) PDZ domain-containing protein 0.0011 0.0003 0.0006
Schistosoma mansoni regulator of G protein signaling 0.0011 0.0003 0.0004
Loa Loa (eye worm) AGC/MAST/MAST protein kinase 0.0011 0.0003 0.0006
Echinococcus granulosus dnaJ subfamily B 0.0399 0.4569 0.5815
Plasmodium vivax NADPH-cytochrome p450 reductase, putative 0.0455 0.5223 1
Echinococcus granulosus methionine synthase reductase 0.0281 0.3178 0.4045
Mycobacterium ulcerans electron transfer protein FdxB 0.0052 0.0484 0.085
Brugia malayi Shank2E 0.0011 0.0003 0.0006
Plasmodium falciparum NADH-cytochrome b5 reductase, putative 0.0052 0.0484 0.0927
Loa Loa (eye worm) hypothetical protein 0.0014 0.0044 0.0084
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0165 0.0257
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0013 0.0032 0.005
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0109 0.0209
Loa Loa (eye worm) hypothetical protein 0.0049 0.0448 0.0858
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.0174 0.1922 0.364
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0294 0.0553
Schistosoma mansoni hypothetical protein 0.0011 0.0003 0.0004
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0016 0.0059 0.0825
Brugia malayi PX domain containing protein 0.0011 0.0003 0.0006
Leishmania major cathepsin L-like protease 0.0063 0.0614 0.1121
Loa Loa (eye worm) PX domain-containing protein 0.0011 0.0003 0.0006
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0032 0.005
Schistosoma mansoni hypothetical protein 0.0011 0.0003 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0032 0.005
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0036 0.0008
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0294 0.0505
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0032 0.005
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0294 0.0553
Brugia malayi Guanylate kinase family protein 0.0011 0.0003 0.0006
Echinococcus granulosus neurabin 1 0.0011 0.0003 0.0004
Schistosoma mansoni PDZ domain protein 0.0011 0.0003 0.0004
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0109 0.0139
Trypanosoma cruzi Flavodoxin/Radical SAM superfamily/Wyosine base formation, putative 0.0174 0.1922 0.364
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0257 0.0491
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0011 0.0003 0.0003
Echinococcus granulosus syndecan binding protein syntenin 0.0011 0.0003 0.0004
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0165 0.0257
Brugia malayi latrophilin 2 splice variant baaae 0.007 0.0698 0.1336
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0049 0.0448 0.078
Schistosoma mansoni leucine-rich repeat protein 0.0011 0.0003 0.0004
Schistosoma mansoni hypothetical protein 0.0032 0.0257 0.0327
Echinococcus multilocularis rho guanine nucleotide exchange factor 12 0.0011 0.0003 0.0003
Echinococcus granulosus FTZ F1 alpha 0.002 0.0109 0.0139
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0032 0.005
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0165 0.0654
Loa Loa (eye worm) gopc protein 0.0011 0.0003 0.0006
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0109 0.0209
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0109 0.0139
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0448 0.0571
Brugia malayi cathepsin L-like precursor 0.0011 0.0006 0.0011
Loa Loa (eye worm) CXXC zinc finger family protein 0.0059 0.0564 0.108
Echinococcus multilocularis cpg binding protein 0.0062 0.0604 0.0604
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.007 0.0123
Brugia malayi hypothetical protein 0.0011 0.0003 0.0006
Echinococcus granulosus bloom syndrome protein 0.0025 0.0176 0.0224
Toxoplasma gondii NADH-cytochrome b5 reductase 1, putative 0.0052 0.0484 0.1914
Onchocerca volvulus 0.0011 0.0006 0.0031
Schistosoma mansoni multiple pdz domain protein 0.0011 0.0003 0.0004
Schistosoma mansoni protein kinase C alpha binding protein 0.0011 0.0003 0.0004
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.0032 0.005
Echinococcus granulosus peripheral plasma membrane protein CASK 0.0011 0.0003 0.0004
Brugia malayi cell junction protein LIN-7 0.0011 0.0003 0.0006
Schistosoma mansoni dishevelled 0.0011 0.0003 0.0004
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0294 0.0505
Onchocerca volvulus 0.0014 0.0044 0.0428
Trichomonas vaginalis glutaminase, putative 0.0267 0.3014 0.5765
Onchocerca volvulus 0.0049 0.0448 0.462
Brugia malayi Hypothetical 13.5 kDa protein C45G9.7 in chromosome III 0.0011 0.0003 0.0006
Onchocerca volvulus Cathepsin L homolog 0.0016 0.007 0.0696
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0671 0.0854
Leishmania major cathepsin L-like protease 0.0063 0.0614 0.1121
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0011 0.0003 0.0004
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0049 0.0448 0.9218
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0011 0.0003 0.0006
Schistosoma mansoni multiple pdz domain protein 0.0011 0.0003 0.0004
Schistosoma mansoni hypothetical protein 0.0011 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0036 0.0303 0.0581
Brugia malayi hypothetical protein 0.0011 0.0003 0.0006
Echinococcus multilocularis myeloid:lymphoid or mixed lineage leukemia 0.0011 0.0003 0.0003
Echinococcus multilocularis disks large 3 0.0011 0.0003 0.0003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.007 0.0123
Leishmania major p450 reductase, putative 0.0455 0.5223 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0052 0.0484 1
Echinococcus multilocularis pdz domain containing protein 0.0011 0.0003 0.0003
Schistosoma mansoni NADPH flavin oxidoreductase 0.0229 0.257 0.3271
Schistosoma mansoni NADH-cytochrome B5 reductase 0.0052 0.0484 0.0616
Echinococcus granulosus NADH cytochrome b5 reductase 3 0.0052 0.0484 0.0616
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.028 0.5596
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0059 0.0113
Loa Loa (eye worm) hypothetical protein 0.002 0.0109 0.0209
Trichomonas vaginalis sulfite reductase, putative 0.0455 0.5223 1
Schistosoma mansoni hypothetical protein 0.007 0.0698 0.0888
Plasmodium vivax vivapain-2 0.0016 0.007 0.005
Echinococcus multilocularis Rho GTPase activating protein 21 0.0011 0.0003 0.0003
Brugia malayi abnormal cell lineage protein 10 (Protein lin-10), putative 0.0011 0.0003 0.0006
Onchocerca volvulus 0.0059 0.0564 0.5829
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Mycobacterium tuberculosis Probable monooxygenase 0.0052 0.0484 1
Schistosoma mansoni hypothetical protein 0.0124 0.1332 0.1696
Onchocerca volvulus 0.0016 0.007 0.0696
Loa Loa (eye worm) hypothetical protein 0.0036 0.0303 0.0581
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.007 0.007
Schistosoma mansoni coup transcription factor 0.002 0.0109 0.0139
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.0011 0.0003 0.0004
Echinococcus granulosus NADPH dependent diflavin oxidoreductase 1 0.0455 0.5223 0.6648
Schistosoma mansoni hypothetical protein 0.0011 0.0003 0.0004
Schistosoma mansoni Patj homolog 0.0011 0.0003 0.0004
Echinococcus multilocularis protein lin 7 B 0.0011 0.0003 0.0003
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0032 0.005
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0448 0.0858
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0294 0.0553
Brugia malayi hypothetical protein 0.0011 0.0003 0.0006
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0614 0.1121
Mycobacterium ulcerans glutaminase 0.0267 0.3014 0.5734
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0052 0.0484 0.0871
Plasmodium vivax vivapain-2 0.0016 0.007 0.005
Brugia malayi syntenin 0.0011 0.0003 0.0006
Schistosoma mansoni thyroid hormone receptor 0.0144 0.1565 0.1992
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0109 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0032 0.005
Echinococcus granulosus cytochrome b5 reductase 4 0.0052 0.0484 0.0616
Loa Loa (eye worm) RasGEF domain-containing protein 0.0011 0.0003 0.0006
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0109 0.0109
Brugia malayi PDZ domain containing protein 0.0011 0.0003 0.0006
Trypanosoma brucei NADH-dependent fumarate reductase 0.0052 0.0484 0.0871
Leishmania major acetyl-CoA synthetase, putative 0.0014 0.0044 0.0023
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0052 0.0484 0.0871
Schistosoma mansoni hypothetical protein 0.0165 0.182 0.2317
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0014 0.0044 0.0056
Schistosoma mansoni alpha glucosidase 0.0036 0.0294 0.0375
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0011 0.0003 0.0004
Echinococcus multilocularis thyroid hormone receptor alpha 0.0144 0.1565 0.1565
Schistosoma mansoni hypothetical protein 0.0011 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0102 0.1078 0.2064
Loa Loa (eye worm) hypothetical protein 0.0036 0.0303 0.0581
Loa Loa (eye worm) DIX domain-containing protein 0.0011 0.0003 0.0006
Loa Loa (eye worm) glutaminase 0.0267 0.3014 0.577
Brugia malayi ecdysteroid receptor 0.002 0.0109 0.0209
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0174 0.1922 0.3672
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0059 0.0075
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0059 0.0059
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.0448 1
Loa Loa (eye worm) peripheral plasma membrane protein CASK 0.0011 0.0003 0.0006
Brugia malayi Partitioning defective-6 homolog alpha 0.0011 0.0003 0.0006
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0448 0.078
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0165 0.0317
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0124 0.1336 0.17
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0109 0.0209
Schistosoma mansoni nuclear hormone receptor 0.002 0.0109 0.0139
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0614 0.1121
Echinococcus multilocularis pdz domain containing protein 0.0011 0.0003 0.0003
Brugia malayi Neurabin protein 1 0.0011 0.0003 0.0006
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0016 0.007 0.0134
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0109 0.0209
Loa Loa (eye worm) hypothetical protein 0.0014 0.0044 0.0084
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.007 0.0123
Trichomonas vaginalis maltase-glucoamylase, putative 0.0013 0.0032 0.005
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0294 0.0553
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0044 0.0023
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0109 0.0209
Echinococcus multilocularis syndecan binding protein (syntenin) 0.0011 0.0003 0.0003
Echinococcus granulosus lysosomal alpha glucosidase 0.016 0.176 0.2241
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0294 0.0564
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0109 0.0209
Plasmodium falciparum NADPH--cytochrome P450 reductase, putative 0.0174 0.1922 0.3679
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0044 0.0084
Echinococcus multilocularis MAGUK p55 subfamily 0.0011 0.0003 0.0003
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0102 0.1078 0.2064
Schistosoma mansoni hypothetical protein 0.0032 0.0257 0.0327
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0015 0.0047 0.0047
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0014 0.0044 0.0084
Onchocerca volvulus 0.0016 0.007 0.0696
Onchocerca volvulus 0.0049 0.0448 0.4624
Echinococcus granulosus segment polarity protein dishevelled 0.0011 0.0003 0.0004
Loa Loa (eye worm) cytochrome b5 reductase 4 0.0052 0.0484 0.0927
Schistosoma mansoni alpha-glucosidase 0.0138 0.1498 0.1907
Mycobacterium tuberculosis Hypothetical oxidoreductase 0.0052 0.0484 1
Plasmodium falciparum nitric oxide synthase, putative 0.0455 0.5223 1
Toxoplasma gondii ferredoxin NADP+ oxidoreductase FNR 0.0052 0.0484 0.1914
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0016 0.007 0.0134
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0016 0.007 0.0134
Mycobacterium ulcerans oxygenase 0.0052 0.0484 0.085
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0006 0.0008
Echinococcus multilocularis geminin 0.0165 0.182 0.182
Schistosoma mansoni hypothetical protein 0.0011 0.0003 0.0004
Schistosoma mansoni hypothetical protein 0.0011 0.0003 0.0004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.007 0.0123
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Leishmania major NADPH-cytochrome p450 reductase-like protein 0.0455 0.5223 1
Schistosoma mansoni cytochrome P450 reductase 0.0455 0.5223 0.6648
Echinococcus granulosus Rho GTPase activating protein 21 0.0011 0.0003 0.0004
Trypanosoma cruzi NADH-dependent fumarate reductase, putative 0.0052 0.0484 0.0871
Echinococcus granulosus geminin 0.0165 0.182 0.2317
Echinococcus multilocularis NADPH cytochrome P450 reductase 0.0455 0.5223 0.5223
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Loa Loa (eye worm) guanylate kinase 0.0011 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0052 0.0484 0.0871
Toxoplasma gondii flavodoxin domain-containing protein 0.0226 0.2529 1
Onchocerca volvulus 0.0093 0.0966 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Echinococcus multilocularis PDZ and LIM domain protein Zasp 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.007 0.0123
Schistosoma mansoni discs large 0.0011 0.0003 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.007 0.0123
Plasmodium vivax oxidoreductase NAD-binding domain containing protein 0.0052 0.0484 0.085
Echinococcus multilocularis PDZ and LIM domain protein Zasp 0.0011 0.0003 0.0003
Echinococcus granulosus pdz domain containing protein 0.0011 0.0003 0.0004
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0014 0.0044 0.0023
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0448 0.2307
Onchocerca volvulus 0.0016 0.007 0.0696
Brugia malayi PDZ domain 0.0011 0.0003 0.0006
Echinococcus granulosus multiple pdz domain protein 0.0011 0.0003 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0614 0.1121
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0294 0.0553
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.176 0.176
Trypanosoma brucei S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.0174 0.1922 0.364
Schistosoma mansoni thyroid hormone receptor 0.0144 0.1565 0.1992
Schistosoma mansoni sh3 and multiple ankyrin repeat domains protein 12 (shank12) 0.0011 0.0003 0.0004
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.028 0.5596
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0052 0.0484 0.0871
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0014 0.0044 0.0503
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0017 0.0079 0.0067
Brugia malayi rho guanine nucleotide exchange factor 12 0.0011 0.0003 0.0006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.007 0.0123
Brugia malayi Calcitonin receptor-like protein seb-1 0.0102 0.1078 0.2064
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0059 0.0052
Schistosoma mansoni discs lost-related 0.0011 0.0003 0.0004
Leishmania major NADH-cytochrome b5 reductase, putative 0.0052 0.0484 0.0871
Brugia malayi Cathepsin L-like precursor 0.0016 0.007 0.0134
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0109 0.0109
Leishmania major cathepsin L-like protease 0.0016 0.007 0.0073
Schistosoma mansoni microtubule-associated protein tau 0.0679 0.7857 1
Leishmania major NADH-cytochrome b5 reductase, putative 0.0052 0.0484 0.0871
Loa Loa (eye worm) hypothetical protein 0.0049 0.0448 0.0858
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0294 0.0553
Trypanosoma cruzi nitrate reductase, putative 0.0052 0.0484 0.0871
Brugia malayi Cathepsin L-like precursor 0.0016 0.007 0.0134
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0059 0.0233
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0109 0.0209
Trichomonas vaginalis NADPH fad oxidoreductase, putative 0.0403 0.4615 0.8835
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0294 0.0375
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0614 0.1121
Echinococcus multilocularis 55 kDa erythrocyte membrane protein 0.0011 0.0003 0.0003
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0044 0.0023
Echinococcus granulosus SH3 and multiple ankyrin repeat domains protein 0.0011 0.0003 0.0004
Leishmania major cathepsin L-like protease 0.0016 0.007 0.0073
Schistosoma mansoni hypothetical protein 0.0399 0.4569 0.5815
Leishmania major cytochrome-b5 reductase, putative 0.0052 0.0484 0.0871
Echinococcus granulosus tar DNA binding protein 0.0068 0.0671 0.0854
Echinococcus multilocularis ligand of numb protein x 2 0.0011 0.0003 0.0003
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.007 0.0134
Echinococcus granulosus cpg binding protein 0.0062 0.0604 0.0768
Echinococcus multilocularis amyloid beta A4 protein 0.0011 0.0003 0.0003
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0109 0.0109
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0109 0.0209
Entamoeba histolytica type A flavoprotein, putative 0.0174 0.1922 1
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0614 0.1121
Schistosoma mansoni lin-7-like proteins 0.0011 0.0003 0.0004
Echinococcus multilocularis multiple pdz domain protein 0.0011 0.0003 0.0003
Loa Loa (eye worm) RNA binding protein 0.0068 0.0671 0.1285
Giardia lamblia Nitric oxide synthase, inducible 0.0403 0.4615 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0059 0.0059
Leishmania major cysteine peptidase A (CPA) 0.0016 0.007 0.0073
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0257 0.0491
Brugia malayi Cathepsin L-like precursor 0.0011 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Brugia malayi hypothetical protein 0.0011 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0049 0.0448 0.0858
Schistosoma mansoni MAGUK homolog 0.0011 0.0003 0.0004
Onchocerca volvulus 0.002 0.0109 0.1103
Echinococcus multilocularis bloom syndrome protein 0.0025 0.0176 0.0176
Echinococcus granulosus pdz domain containing protein 0.0011 0.0003 0.0004
Trypanosoma cruzi oxidoreductase-protein, putative 0.0052 0.0484 0.0871
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0257 0.0257
Schistosoma mansoni hypothetical protein 0.0011 0.0003 0.0004
Schistosoma mansoni cpg binding protein 0.0059 0.0564 0.0718
Echinococcus multilocularis GPCR, family 2 0.0032 0.0257 0.0257
Schistosoma mansoni syntrophin 0.0011 0.0003 0.0004
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0328 0.0417
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0109 0.0139
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0049 0.0448 0.078
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0044 0.0503
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0614 0.1121
Echinococcus multilocularis microtubule associated protein 2 0.0679 0.7857 0.7857
Trypanosoma brucei NADH-cytochrome b5 reductase, putative 0.0052 0.0484 0.0871
Loa Loa (eye worm) cysteine protease 0.0016 0.007 0.0134
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0032 0.005
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0022 0.014 0.0267
Echinococcus granulosus MAGUK p55 subfamily 0.0011 0.0003 0.0004
Entamoeba histolytica hypothetical protein 0.0038 0.0328 0.168
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.007 0.0089
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0109 0.0209
Leishmania major acetyl-CoA synthetase, putative 0.0014 0.0044 0.0023
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0059 0.0113
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0014 0.0044 0.0503
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.007 0.0123
Schistosoma mansoni amyloid beta A4 protein related 0.0011 0.0003 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.007 0.0123
Echinococcus granulosus microtubule associated protein 2 0.0679 0.7857 1
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0124 0.1332 0.1332
Echinococcus multilocularis cytochrome b5 reductase 4 0.0052 0.0484 0.0484
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.007 0.0134
Brugia malayi glutaminase DH11.1 0.0267 0.3014 0.577
Entamoeba histolytica type A flavoprotein, putative 0.0174 0.1922 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0109 0.0209
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0011
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0032 0.005
Echinococcus multilocularis microtubule associated serine:threonine protein 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Echinococcus granulosus NADPH cytochrome P450 reductase 0.0455 0.5223 0.6648
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0109 0.0209
Loa Loa (eye worm) hypothetical protein 0.002 0.0109 0.0209
Echinococcus multilocularis pdz domain containing protein 0.0011 0.0003 0.0003
Brugia malayi Glycosyl hydrolases family 31 protein 0.016 0.176 0.337
Echinococcus granulosus MAGUK p55 subfamily 0.0011 0.0003 0.0004
Onchocerca volvulus 0.0014 0.0044 0.0428
Echinococcus granulosus pdz domain containing protein 0.0011 0.0003 0.0004
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0109 0.0109
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0017 0.0077 0.0303
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0013 0.0032 0.0136
Echinococcus granulosus membrane associated guanylate kinase ww and pdz 0.0011 0.0003 0.0004
Toxoplasma gondii propionate-CoA ligase 0.0014 0.0044 0.0174
Entamoeba histolytica cysteine protease, putative 0.0016 0.007 0.0334
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0456 0.0817
Schistosoma mansoni cell polarity protein 0.0011 0.0003 0.0004
Schistosoma mansoni lim domain 0.0011 0.0003 0.0004
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0014 0.0044 0.0503
Brugia malayi Protein-tyrosine phosphatase 1 0.0011 0.0003 0.0006
Onchocerca volvulus 0.0016 0.007 0.0696
Echinococcus multilocularis PRKCA binding protein 0.0011 0.0003 0.0003
Trichomonas vaginalis DNA helicase recq, putative 0.0025 0.0176 0.0326
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Brugia malayi flavodoxin family protein 0.0455 0.5223 1
Echinococcus multilocularis MAGUK p55 subfamily 0.0011 0.0003 0.0003
Schistosoma mansoni ATP-dependent RNA Helicase 0.0011 0.0003 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0614 0.1121
Onchocerca volvulus 0.0014 0.0044 0.0428
Mycobacterium tuberculosis Possible oxygenase 0.0052 0.0484 1
Brugia malayi PDZ domain containing protein 0.0011 0.0003 0.0006
Schistosoma mansoni maguk P55 subfamily member 26 0.0011 0.0003 0.0004
Entamoeba histolytica type A flavoprotein, putative 0.0174 0.1922 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0257 0.0327
Echinococcus granulosus cathepsin L cysteine proteinase 0.0016 0.007 0.0089
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0032 0.005
Entamoeba histolytica type A flavoprotein, putative 0.0174 0.1922 1
Brugia malayi steroid hormone receptor 0.002 0.0109 0.0209
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.0011 0.0003 0.0004
Brugia malayi RasGEF domain containing protein 0.0011 0.0003 0.0006
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0109 0.0209
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.007 0.0334
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Loa Loa (eye worm) FAD binding domain-containing protein 0.0455 0.5223 1
Entamoeba histolytica recQ family helicase, putative 0.0014 0.0036 0.0159
Echinococcus multilocularis multiple pdz domain protein 0.0011 0.0003 0.0003
Plasmodium falciparum ferredoxin--NADP reductase 0.0052 0.0484 0.0927
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.007 0.0123
Echinococcus multilocularis membrane associated guanylate kinase ww and pdz 0.0011 0.0003 0.0003
Schistosoma mansoni pdz and lim domain protein 0.0011 0.0003 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.007 0.0123
Schistosoma mansoni hypothetical protein 0.0032 0.0257 0.0327
Echinococcus granulosus glutamate receptor interacting protein 1 0.0011 0.0003 0.0004
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0294 0.1164
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0052 0.0484 0.0871
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0614 0.1121
Brugia malayi gopc protein 0.0011 0.0003 0.0006
Trypanosoma brucei oxidoreductase-protein, putative 0.0052 0.0484 0.0871
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0032 0.005
Echinococcus multilocularis tar DNA binding protein 0.0068 0.0671 0.0671
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0011 0.0003 0.0003
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.0448 1
Echinococcus granulosus Na:H exchange regulatory cofactor NHE RF2 0.0011 0.0003 0.0004
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0671 0.0854
Echinococcus multilocularis Partitioning defective 3 protein B 0.0011 0.0003 0.0003
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0036 0.0303 0.0501
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.007 0.0123
Loa Loa (eye worm) hypothetical protein 0.0128 0.1385 0.2651
Echinococcus granulosus PDZ and LIM domain protein Zasp 0.0011 0.0003 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0614 0.1121
Trichomonas vaginalis DNA helicase recq, putative 0.0014 0.0036 0.0058
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.028 0.5596
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.016 0.176 0.337
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0014 0.0044 0.0174
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.007 0.0123
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Echinococcus multilocularis SH3 and multiple ankyrin repeat domains protein 0.0011 0.0003 0.0003
Plasmodium vivax hypothetical protein, conserved 0.0174 0.1922 0.3625
Leishmania major nitrate reductase, putative 0.0052 0.0484 0.0871
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0448 0.0858
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Brugia malayi Guanylate kinase family protein 0.0011 0.0003 0.0006
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0109 0.0139
Echinococcus granulosus multiple pdz domain protein 0.0011 0.0003 0.0004
Echinococcus granulosus disks large 3 0.0011 0.0003 0.0004
Brugia malayi hypothetical protein 0.0025 0.0165 0.0317
Echinococcus granulosus PRKCA binding protein 0.0011 0.0003 0.0004
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0328 0.0417
Schistosoma mansoni alpha-glucosidase 0.0138 0.1498 0.1907
Echinococcus multilocularis beta 1 syntrophin 0.0011 0.0003 0.0003
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.007 0.0334
Schistosoma mansoni cell polarity protein 0.0011 0.0003 0.0004
Echinococcus multilocularis disks large 1 0.0011 0.0003 0.0003
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0036 0.0303 0.0946
Echinococcus granulosus membrane associated guanylate kinase, WW and PDZ 0.0011 0.0003 0.0004
Loa Loa (eye worm) hypothetical protein 0.0036 0.0303 0.0581
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0032 0.005
Loa Loa (eye worm) hypothetical protein 0.0013 0.0032 0.0061
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0109 0.0139
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0014 0.0044 0.0503
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0044 0.0023
Trypanosoma cruzi cytochrome P450 reductase, putative 0.0455 0.5223 1
Trypanosoma brucei NADPH--cytochrome P450 reductase, putative 0.0455 0.5223 1
Trypanosoma brucei NADH-dependent fumarate reductase, putative 0.0052 0.0484 0.0871
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0109 0.1103
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.007 0.0123
Echinococcus multilocularis PDZ domain containing protein GIPC3 0.0011 0.0003 0.0003
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.007 0.007
Echinococcus multilocularis SH3 and multiple ankyrin repeat domains protein 0.0011 0.0003 0.0003
Schistosoma mansoni cytochrome B5 0.0052 0.0484 0.0616
Trichomonas vaginalis helicase, putative 0.0013 0.0032 0.005
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0059 0.0059
Echinococcus multilocularis methionine synthase reductase 0.0281 0.3178 0.3178
Echinococcus multilocularis pdz domain containing protein 0.0011 0.0003 0.0003
Trypanosoma brucei NADPH-cytochrome p450 reductase, putative 0.0455 0.5223 1
Echinococcus granulosus protein lin 7 B 0.0011 0.0003 0.0004
Leishmania major reductase, putative 0.0052 0.0484 0.0871
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0036 0.0008
Loa Loa (eye worm) syntrophin-1 0.0011 0.0003 0.0006
Echinococcus multilocularis protein piccolo 0.0011 0.0003 0.0003
Loa Loa (eye worm) TAR-binding protein 0.0068 0.0671 0.1285
Loa Loa (eye worm) hypothetical protein 0.0011 0.0006 0.0011
Onchocerca volvulus Cathepsin L homolog 0.0016 0.007 0.0696
Echinococcus granulosus cytochrome b5 reductase 4 0.0052 0.0484 0.0616
Loa Loa (eye worm) PAR-6 protein 0.0011 0.0003 0.0006
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0049 0.0448 0.078
Plasmodium falciparum S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, putative 0.0174 0.1922 0.3679
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0109 0.0139
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0044 0.0084
Trichomonas vaginalis NADPH cytochrome P450, putative 0.0174 0.1922 0.3672
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0124 0.1332 0.1696
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0044 0.0073
Loa Loa (eye worm) hypothetical protein 0.0032 0.0257 0.0491
Brugia malayi Cathepsin L-like precursor 0.0016 0.007 0.0134
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0109 0.0209
Echinococcus granulosus membrane associated guanylate kinase ww and pdz 0.0011 0.0003 0.0004
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0014 0.0044 0.0044
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0052 0.0484 0.0871
Trypanosoma cruzi cruzipain precursor, putative 0.0063 0.0614 0.1121
Chlamydia trachomatis Na(+)-translocating NADH-quinone reductase subunit F 0.0052 0.0484 0.1516
Echinococcus granulosus Microtubule-associated serine/threonine-protein kinase 0.0011 0.0003 0.0004
Mycobacterium ulcerans hypothetical protein 0.0049 0.0448 0.078
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0109 0.0209
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0059 0.0233
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Trypanosoma brucei NADH-cytochrome b5 reductase-like protein 0.0052 0.0484 0.0871
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0032 0.005
Echinococcus multilocularis SH3 and multiple ankyrin repeat domains protein 0.0011 0.0003 0.0003
Loa Loa (eye worm) cell junction protein LIN-7 0.0011 0.0003 0.0006
Treponema pallidum flavodoxin 0.0174 0.1922 1
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0014 0.0044 0.0503
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0448 0.9218
Brugia malayi hypothetical protein 0.0011 0.0003 0.0006
Trypanosoma cruzi NADH-cytochrome b5 reductase, putative 0.0052 0.0484 0.0871
Chlamydia trachomatis sulfite reductase 0.0281 0.3178 1
Brugia malayi Cathepsin L-like precursor 0.0011 0.0006 0.0011
Brugia malayi Bloom's syndrome protein homolog 0.0025 0.0176 0.0337
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0015 0.0047 0.006
Brugia malayi Synapse defective protein 1 0.0011 0.0003 0.0006
Brugia malayi Cathepsin L-like precursor 0.0016 0.007 0.0134
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0013 0.0032 0.005
Schistosoma mansoni multiple pdz domain protein 0.0011 0.0003 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0614 0.1121
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0109 0.1103
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.002 0.0109 0.0209
Leishmania major hypothetical protein, conserved 0.0025 0.0165 0.0257
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0109 0.0209
Echinococcus granulosus mixed lineage leukemia protein mll 0.0015 0.0047 0.006
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0109 0.0139
Schistosoma mansoni 5-methyl tetrahydrofolate-homocysteine methyltransferase reductase 0.0281 0.3178 0.4045

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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